4.4.1.20: leukotriene-C4 synthase
This is an abbreviated version!
For detailed information about leukotriene-C4 synthase, go to the full flat file.
Word Map on EC 4.4.1.20
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4.4.1.20
-
asthma
-
lta4
-
cysteinyl
-
5-lipoxygenase
-
arachidonic
-
eosinophil
-
asthmatic
-
flap
-
bronchial
-
eicosanoids
-
aspirin
-
cysteinyl-leukotrienes
-
cys-lts
-
cysltr1
-
aspirin-induced
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bronchoconstriction
-
5-lipoxygenase-activating
-
aspirin-intolerant
-
alox5ap
-
montelukast
-
1-chloro-2,4-dinitrobenzene
-
mapeg
-
aspirin-exacerbated
-
rbl-1
-
medicine
-
bronchoconstrictors
-
a23187-stimulated
-
molecular biology
-
drug development
-
analysis
- 4.4.1.20
- asthma
- lta4
-
cysteinyl
-
5-lipoxygenase
-
arachidonic
-
eosinophil
-
asthmatic
- flap
- bronchial
-
eicosanoids
- aspirin
- cysteinyl-leukotrienes
-
cys-lts
-
cysltr1
-
aspirin-induced
-
bronchoconstriction
-
5-lipoxygenase-activating
-
aspirin-intolerant
-
alox5ap
- montelukast
- 1-chloro-2,4-dinitrobenzene
-
mapeg
-
aspirin-exacerbated
- rbl-1
- medicine
-
bronchoconstrictors
-
a23187-stimulated
- molecular biology
- drug development
- analysis
Reaction
Synonyms
(7E,9E,11Z,14Z)-(5S,6S)-5,6-epoxyicosa-7,9,11,14-tetraenoate:glutathione leukotriene-transferase (epoxide-ring-opening), EC 2.5.1.37, leukotriene A4:glutathione S-leukotrienyltransferase, leukotriene C4 synthase, leukotriene C4 synthetase, LT C4 synthase, LTC4 synthase, LTC4 synthetase, LTC4S, LTCS, synthase, leukotriene C4
ECTree
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Turnover Number
Turnover Number on EC 4.4.1.20 - leukotriene-C4 synthase
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26
glutathione
pH 7.8, temperature not specified in the publication, recombinant wild-type enzyme
32
glutathione
pH 7.8, temperature not specified in the publication, recombinant mutant W116A
74.3
glutathione
pH 7.8, temperature not specified in the publication, recombinant mutant W116F
84
glutathione
pH 7.8, temperature not specified in the publication, recombinant enzyme
0.5
mutant R104S, 22°C, pH not specified in the publication
0.66
leukotriene A4
mutant R104A, 22°C, pH not specified in the publication
1.4
leukotriene A4
mutant R31A, 22°C, pH not specified in the publication
1.8
leukotriene A4
mutant R31Q, 22°C, pH not specified in the publication
12
leukotriene A4
pH 7.8, temperature not specified in the publication, recombinant wild-type enzyme
16.8
leukotriene A4
pH 7.8, temperature not specified in the publication, recombinant mutant W116A
17.7
leukotriene A4
pH 7.8, temperature not specified in the publication, recombinant mutant W116F
81
leukotriene A4
pH 7.8, temperature not specified in the publication, recombinant enzyme