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Literature summary for 4.4.1.20 extracted from

  • Schroder, O.; Sjostrom, M.; Qiu, H.; Jakobsson, P.J.; Haeggstrom, J.Z.
    Microsomal glutathione S-transferases: selective up-regulation of leukotriene C4 synthase during lipopolysaccharide-induced pyresis (2005), Cell. Mol. Life Sci., 62, 87-94.
    View publication on PubMed
Search for more literature for 4.4.1.20

Activating Compound

Activating Compound Comment Organism Structure
lipopolysaccharide from Escherichia coli serotype O26:B26, increases mRNA expression in heart, brain, liver and adrenal gland Rattus norvegicus

Cloned(Commentary)

Cloned (Comment) Organism
-
 Rattus norvegicus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
18000
-
 x * 18000, SDS-PAGE Rattus norvegicus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
leukotriene C4 Rattus norvegicus
-
 leukotriene A4 + glutathione
-
 r

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
adrenal gland
-
 Rattus norvegicus
-
brain
-
 Rattus norvegicus
-
colon
-
 Rattus norvegicus
-
heart
-
 Rattus norvegicus
-
ileum
-
 Rattus norvegicus
-
liver
-
 Rattus norvegicus
-
lung
-
 Rattus norvegicus
-
skeletal muscle
-
 Rattus norvegicus
-
spleen
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
leukotriene A4 + glutathione pH 7.4, room temperature Rattus norvegicus leukotriene C4
-
 r
leukotriene C4
-
 Rattus norvegicus leukotriene A4 + glutathione
-
 r

Subunits

Subunits Comment Organism
? x * 18000, SDS-PAGE Rattus norvegicus

Synonyms

Synonyms Comment Organism
leukotriene C4 synthase
-
 Rattus norvegicus
LTC4S
-
 Rattus norvegicus