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Literature summary for 4.4.1.20 extracted from
- Leukotriene synthesis is increased by transcriptional up-regulation of 5-lipoxygenase, leukotriene A4 hydrolase, and leukotriene C4 synthase in asthmatic children (2003), J. Asthma, 40, 147-154.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| A23187 | a calcium ionophore | Homo sapiens |  |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| leukotriene C4 | Homo sapiens | - |
leukotriene A4 + glutathione | - |
r | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | Q16873 | - |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| polymorphonuclear leukocyte | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| leukotriene C4 | - |
Homo sapiens | leukotriene A4 + glutathione | - |
r | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| leukotriene C4 synthase | - |
Homo sapiens |
| LTC4 synthase | - |
Homo sapiens |
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