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Literature summary for 4.4.1.20 extracted from

  • Abe, M.; Shibata, K.; Urata, H.; Sakata, N.; Katsuragi, T.
    Induction of leukotriene C4 synthase after the differentiation of rat basophilic leukemia cells with retinoic acid and a low dose of actinomycin D and its suppression with methylprednisolone (2003), J. Cell. Physiol., 196, 154-164.
    View publication on PubMed
Search for more literature for 4.4.1.20

Activating Compound

Activating Compound Comment Organism Structure
actinomycin D in addition to retinoic acid Rattus norvegicus
daunorubicin
-
 Rattus norvegicus
mitomycin C
-
 Rattus norvegicus
retinoic acid
-
 Rattus norvegicus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
18000
-
 x * 18000, SDS-PAGE Rattus norvegicus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
leukotriene C4 Rattus norvegicus
-
 leukotriene A4 + glutathione
-
 r

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
RBL-1 cell
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
leukotriene A4 free acid + glutathione pH 7.4, 37°C Rattus norvegicus leukotriene C4
-
 r
leukotriene A4 methylester + glutathione pH 7.4, 37°C Rattus norvegicus leukotriene C4 methylester
-
 r
leukotriene C4
-
 Rattus norvegicus leukotriene A4 + glutathione
-
 r

Subunits

Subunits Comment Organism
? x * 18000, SDS-PAGE Rattus norvegicus

Synonyms

Synonyms Comment Organism
leukotriene C4 synthase
-
 Rattus norvegicus
LTC4S
-
 Rattus norvegicus