EC Number |
Recommended Name |
Localization |
GeneOntology No. |
Reference |
---|
1.1.1.170 | 3beta-hydroxysteroid-4alpha-carboxylate 3-dehydrogenase (decarboxylating) |
lipid droplet |
surface of |
GO:0005811 AmiGO QuickGO |
722377 |
1.1.1.265 | 3-methylbutanal reductase |
lipid droplet |
- |
GO:0005811 AmiGO QuickGO |
-, 763285 |
1.1.1.300 | NADP-retinol dehydrogenase |
lipid droplet |
- |
GO:0005811 AmiGO QuickGO |
740719 |
1.17.1.4 | xanthine dehydrogenase |
lipid droplet |
fat-globule, milk |
GO:0005811 AmiGO QuickGO |
644618 |
1.17.3.2 | xanthine oxidase |
lipid droplet |
- |
GO:0005811 AmiGO QuickGO |
644640 |
1.17.3.2 | xanthine oxidase |
lipid droplet |
enzyme is associated with bovine milk-fat-globule membrane |
GO:0005811 AmiGO QuickGO |
644622, 644657 |
1.17.3.2 | xanthine oxidase |
lipid droplet |
membrane-bound |
GO:0005811 AmiGO QuickGO |
644640 |
1.17.3.2 | xanthine oxidase |
lipid droplet |
milk lipid globule membrane possesses enzyme activity capable of catalyzing the conversion of xanthine dehydrogenase to xanthine oxidase, kinetic of this process is consistent with the rapid appearence of xanthine oxidase in milk |
GO:0005811 AmiGO QuickGO |
644565 |
1.2.1.48 | long-chain-aldehyde dehydrogenase |
lipid droplet |
- |
GO:0005811 AmiGO QuickGO |
741853 |
1.2.1.84 | alcohol-forming fatty acyl-CoA reductase |
lipid droplet |
- |
GO:0005811 AmiGO QuickGO |
763306 |
2.3.1.135 | phosphatidylcholine-retinol O-acyltransferase |
lipid droplet |
upon initiating retinyl ester biosynthesis in cells, Crpb1 remains with MAM, and both Crbp1 and MAM re-localize with LRAT. LRAT formed rings around the growing lipid droplets. LRAT-containing rings colocalize with the lipid-droplet surface proteins, desnutrin/adipose triglyceride lipase and perilipin 2. Colocalization with lipid droplets requires the 38 N-terminal amino acid residues of LRAT, and specifically K36 and R38. Formation of rings around the growing lipid droplets does not require functional microtubules |
GO:0005811 AmiGO QuickGO |
718992 |
2.3.1.158 | phospholipid:diacylglycerol acyltransferase |
lipid droplet |
- |
GO:0005811 AmiGO QuickGO |
758030 |
2.3.1.20 | diacylglycerol O-acyltransferase |
lipid droplet |
- |
GO:0005811 AmiGO QuickGO |
-, 735702, 736458, 737144, 756745, 758011, 758030, 758179 |
2.3.1.20 | diacylglycerol O-acyltransferase |
lipid droplet |
the interaction of isoform DGAT2 with lipid droplets is dependent on the C-terminus. Mutants, in which regions of the C-terminus are either truncated or specific regions are deleted, failed to co-localize with lipid droplets when cells are oleate loaded to stimulate triacylglycerol synthesis |
GO:0005811 AmiGO QuickGO |
719951 |
2.3.1.22 | 2-acylglycerol O-acyltransferase |
lipid droplet |
MGAT1 localizes to the endoplasmic reticulum under normal conditions, and colocalizes to lipid droplets under conditions of enriching fatty acids, contributing to TAG synthesis and LD expansion |
GO:0005811 AmiGO QuickGO |
756283 |
2.3.1.23 | 1-acylglycerophosphocholine O-acyltransferase |
lipid droplet |
in addition to endoplasmic reticulum, both isoforms LCAT1 and LCAT2 localize to lipid droplets, which consist of a core of neutral lipids surrounded by a monolayer of phospholipid, mainly phosphatidylcholine. This dual localization is enabled by the monotopic topology of the enzymes with both termini facing the cytoplasm, irrespective of supplementation with oleic acid. Lipid droplets have the ability to locally synthesize phosphatidylcholine and this activity correlates with the LPCAT1 and -2 expression levels |
GO:0005811 AmiGO QuickGO |
719936 |
2.3.1.48 | histone acetyltransferase |
lipid droplet |
- |
GO:0005811 AmiGO QuickGO |
-, 756854 |
2.3.1.51 | 1-acylglycerol-3-phosphate O-acyltransferase |
lipid droplet |
- |
GO:0005811 AmiGO QuickGO |
756108 |
2.3.1.51 | 1-acylglycerol-3-phosphate O-acyltransferase |
lipid droplet |
and endoplasmic reticulum |
GO:0005811 AmiGO QuickGO |
720417 |
2.3.1.51 | 1-acylglycerol-3-phosphate O-acyltransferase |
lipid droplet |
white adipose tissue of mice |
GO:0005811 AmiGO QuickGO |
687752 |
2.3.1.75 | long-chain-alcohol O-fatty-acyltransferase |
lipid droplet |
- |
GO:0005811 AmiGO QuickGO |
659060 |
2.3.1.84 | alcohol O-acetyltransferase |
lipid droplet |
isoform Atf1 |
GO:0005811 AmiGO QuickGO |
-, 737129 |
2.7.7.15 | choline-phosphate cytidylyltransferase |
lipid droplet |
CTP:phosphocholine cytidylyltransferase binds stably and via its amphipatic alpha helix to lipid droplet surface during surface expansion, which is essential for the lipid droplet. It is the only enzyme of the phosphatidylecholine synthesis Kennedy pathway that localizes in the lipid droplets |
GO:0005811 AmiGO QuickGO |
721989 |
3.1.1.13 | sterol esterase |
lipid droplet |
redistribution of enzyme from cytosol to lipid droplets upon lipid loading of THP-1 macrophages. Enzyme associates with mixed as well as triacylglycerol depleted droplets, enzyme activity is 2.5fold higher with mixed droplets |
GO:0005811 AmiGO QuickGO |
665963 |
3.1.1.23 | acylglycerol lipase |
lipid droplet |
- |
GO:0005811 AmiGO QuickGO |
714314 |
3.1.1.3 | triacylglycerol lipase |
lipid droplet |
- |
GO:0005811 AmiGO QuickGO |
-, 664561, 730046 |
3.1.1.3 | triacylglycerol lipase |
lipid droplet |
colocalization of isozymes Tgl4p and Tgl5p |
GO:0005811 AmiGO QuickGO |
-, 665672 |
3.1.1.3 | triacylglycerol lipase |
lipid droplet |
the enzyme activity is restricted to lipid droplets |
GO:0005811 AmiGO QuickGO |
730017 |
3.1.1.5 | lysophospholipase |
lipid droplet |
- |
GO:0005811 AmiGO QuickGO |
693213 |
3.1.3.4 | phosphatidate phosphatase |
lipid droplet |
lipin 2 |
GO:0005811 AmiGO QuickGO |
709098 |
3.1.3.4 | phosphatidate phosphatase |
lipid droplet |
lipin-1gamma partially translocates from subcellular membranes to lipid droplets upon fatty acid loading |
GO:0005811 AmiGO QuickGO |
715035 |
3.2.1.21 | beta-glucosidase |
lipid droplet |
two different oleuropein-degradative-beta-glucosidases are present |
GO:0005811 AmiGO QuickGO |
682453 |
3.5.1.99 | fatty acid amide hydrolase |
lipid droplet |
FAAH-2, localization of FAAH-2 on the cytoplasmic face of lipid droplets, lipid droplet localization is essential for FAAH-2 |
GO:0005811 AmiGO QuickGO |
712466 |