Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
1,2,3-trioleoyl-sn-glycerol + H2O
?
1,2-didecanoyl-sn-glycero-3-phosphocholine + H2O
?
-
-
-
-
?
1,2-didecanoylphosphatidylcholine + H2O
?
-
-
-
?
1,2-didodecanoyl-sn-glycero-3-phosphocholine + H2O
?
-
-
-
?
1,2-dioctanoyl-sn-glycero-3-phosphocholine + H2O
?
1,2-dioleoylglycerol + H2O
?
-
-
-
-
?
1,2-dioleoylphosphatidylcholine + H2O
monooleoyl-lysophosphatidylcholine + oleic acid
-
129% of activity with 1,2-dipalmitoylphosphatidylcholine
-
?
1,2-dioleoylphosphatidylethanolamine + H2O
monooleoyl-lysophosphatidylethanolamine + oleic acid
-
-
33.5% of activity with 1,2-dipalmitoylphosphatidylcholine
?
1,2-dioleoylphosphatidylserine + H2O
monooleoyl-lysophosphatidylserine + oleic acid
-
-
22.5% of activity with 1,2-dipalmitoylphosphatidylcholine
?
1,2-dipalmitoyl-sn-glycero-3-phosphocholine + H2O
1-palmitoyl-sn-glycero-3-phosphocholine + palmitate
-
-
-
?
1,2-dipalmitoyl-sn-glycero-3-phosphocholine + H2O
?
1,2-dipalmitoylphosphatidylcholine + H2O
?
1,2-palmitylphosphatidylcholine + H2O
1-palmityl-lysophosphatidylcholine + palmitic acid
-
low activity after activating of ExoU with an unknown eukaryotic cell factor
-
?
1-acyl-2-lysophosphatidylcholine + H2O
fatty acid + glycerophosphocholine
-
-
-
?
1-acyl-2-oleoyl-phosphatidylcholine + H2O
?
-
-
-
-
?
1-acyl-glycerophosphoglycerol + H2O
fatty acid + glcyerophosphoglycerol
-
-
-
-
?
1-acyl-lysophosphatidylcholine + 1-alkyllysophosphatidylcholine
1-alkyl-2-acyl-phosphatidylcholine + glycerylphosphocholine
-
-
-
?
1-acyl-sn-glycero-3-phosphate + H2O
fatty acid + glyceryl phosphate
-
-
-
-
?
1-acyl-sn-glycero-3-phospho-myo-inositol
fatty acid + glycero-3-phospho-myo-inositol
1-acyl-sn-glycero-3-phosphocholine + H2O
fatty acid + glycero-3-phosphocholine
1-acyl-sn-glycero-3-phosphoserine + H2O
fatty acid + glycerophosphoserine
1-acylglycerophosphoethanolamine + H2O
fatty acid + glycerylphosphoethanolamine
1-arachidonoyl-2-lysophosphatidylcholine + H2O
?
-
-
-
-
?
1-arachidonoyl-2-lysophosphatidylcholine + H2O
lysophosphatidylcholine + arachidonic acid
-
-
-
-
?
1-docosahexaenoyl-2-lysophosphatidylcholine + H2O
?
-
-
-
-
?
1-dodecanoyl-sn-glycero-3-phosphocholine + H2O
?
-
-
-
?
1-hexanoyl-2-lysophosphatidylcholine + H2O
?
-
-
-
-
?
1-hexanoyl-2-lysophosphatidylcholine + H2O
glycerophosphocholine + hexanoate
-
-
-
?
1-hexyl-glycerophosphocholine + H2O
hexanoate + glycerophosphocholine
-
-
-
-
?
1-lauroyl lysophosphatidylcholine + H2O
?
-
-
-
-
?
1-lauroyl-2-lysophosphatidylcholine + H2O
?
-
-
-
-
?
1-lauroyl-sn-glycero-3-phosphocholine + H2O
lauric acid + sn-glycero-3-phosphocholine
-
-
-
-
?
1-lauryl-glycerophosphocholine + H2O
laurate + glycerophosphocholine
-
-
-
-
?
1-linoleoyl-2-lysophosphatidylcholine + H2O
?
-
-
-
-
?
1-linoleoyl-2-lysophosphatidylcholine + H2O
lysophosphatidylcholine + linoleic acid
-
-
-
-
?
1-linoleoyl-sn-glycero-3-phosphocholine + H2O
linoleic acid + glycerophosphorylcholine
-
-
-
-
?
1-monopalmitoylglycerol + H2O
glycerol + palmitic acid
-
-
lipase activity of LPLA
?
1-monopalmitoyllysophosphatidylglycerol + H2O
glycerophosphoglycerol + palmitic acid
-
-
?
1-myristoyl-2-(4-nitrophenylsuccinyl) phosphatidylcholine + H2O
?
-
substrate for Lp-PLA2
-
-
?
1-myristoyl-2-lysophosphatidylcholine + H2O
?
-
-
-
-
?
1-myristoyl-2-lysophosphatidylcholine + H2O
lysophosphatidylcholine + myristic acid
-
-
-
-
?
1-myristoyl-sn-glycero-3-phosphocholine + H2O
myristic acid + sn-glycero-3-phosphocholine
-
-
-
-
?
1-O-hexadecyl-2-acetyl-rac-glycero-3-phosphocholine + H2O
1-O-hexadecyl-2-hydroxy-sn-glycero-3-phosphocholine + ?
-
substrate for Lp-PLA2
-
-
?
1-O-hexadecyl-2-hydroxy-sn-glycero-3-phosphocholine + H2O
1-(1-hexadecyl)-sn-glycero-3-phosphate + choline
-
substrate for LysoPLD
-
-
?
1-octanoyl-sn-glycero-3-phosphocholine + H2O
octanoic acid + sn-glycero-3-phosphocholine
-
-
-
-
?
1-oleoyl lysophosphatidylcholine + H2O
?
-
-
-
-
?
1-oleoyl lysophosphatidylcholine + H2O
glycerophosphocholine + oleate
-
30% of the activity with 1-palmitoyl lysophosphatidylcholine, LPL1
-
-
?
1-oleoyl-2-acetyl-sn-glycero-3-phosphocholine + H2O
?
-
-
-
-
?
1-oleoyl-2-lysophosphatidylcholine + H2O
?
-
-
-
-
?
1-oleoyl-2-lysophosphatidylcholine + H2O
glycerophosphocholine + oleate
-
-
-
?
1-oleoyl-2-lysophosphatidylcholine + H2O
glycerophosphocholine + oleic acid
-
-
-
-
?
1-oleoyl-2-lysophosphatidylcholine + H2O
glycerophosphorylcholine + oleic acid
-
30% of the activity with 1-palmitoyl lysophosphatidylcholine at pH 5.0, 667% of the activity with 1-palmitoyl lysophosphatidylcholine at pH 7.0
-
-
?
1-oleoyl-glycerophosphocholine + H2O
oleate + glycerophosphocholine
-
-
-
-
?
1-oleoyl-lysophosphatidylcholine + H2O
glycerophosphorylcholine + oleic acid
-
194% of activity with 1-palmitoyl-lysophosphatidylcholine
-
?
1-oleoyl-sn-glycero-3-phosphocholine + H2O
oleic acid + glycerophosphorylcholine
1-oleoyl-sn-glycero-3-phosphoethanolamine + H2O
oleic acid + glycero-3-phosphoethanolamine
1-palmitoyl lysophosphatidylcholine + H2O
?
-
-
-
-
?
1-palmitoyl lysophosphatidylcholine + H2O
glycerophosphocholine + palmitate
1-palmitoyl lysophosphatidylcholine + H2O
glycerophosphocholine + palmitic acid
-
-
-
-
?
1-palmitoyl-2-acetyl-sn-glycero-3-phosphocholine + H2O
?
1-palmitoyl-2-lyso-sn-phosphatidylcholine + H2O
glycerophosphocholine + palmitic acid
-
-
-
?
1-palmitoyl-2-lysophosphatidylcholine + H2O
?
1-palmitoyl-2-lysophosphatidylcholine + H2O
glycerophosphocholine + palmitate
-
-
-
?
1-palmitoyl-2-lysophosphatidylcholine + H2O
glycerophosphocholine + palmitic acid
1-palmitoyl-2-lysophosphatidylcholine + H2O
palmitate + glycerophosphocholine
-
-
-
-
?
1-palmitoyl-2-oleoylphosphatidylcholine + H2O
lysophosphatidylcholine + ?
-
36% of activity with 1,2-dipalmitoylphosphatidylcholine
-
?
1-palmitoyl-glycerophosphocholine + H2O
palmitate + glycerophosphocholine
-
-
-
-
?
1-palmitoyl-lysophosphatidylcholine + H2O
glycerophosphocholine + palmitic acid
1-palmitoyl-lysophosphatidylethanolamine + H2O
glycerophosphatidylethanolamine + palmitic acid
1-palmitoyl-lysophosphatidylethanolamine + H2O
glycerophosphoethanolamine + palmitate
-
20% of the activity with 1-palmitoyl lysophosphatidylcholine, LPL1
-
-
?
1-palmitoyl-sn-glycero-3-phosphocholine + H2O
?
-
-
-
?
1-palmitoyl-sn-glycero-3-phosphocholine + H2O
glycerophosphocholine + palmitate
-
-
?
1-palmitoyl-sn-glycero-3-phosphocholine + H2O
palmitic acid + glycero-3-phosphocholine
1-palmitoyl-sn-glycero-3-phosphoethanolamine + H2O
palmitic acid + glycero-3-phosphoethanolamine
1-palmitoyl-sn-glycero-3-phosphoserine + H2O
glycerophosphoserine + palmitic acid
1-palmitoyl-sn-glycerol + H2O
palmitic acid + glycerol
-
-
-
-
?
1-stearoyl-2-arachidonoyl-sn-glycerol
?
-
-
-
-
?
1-stearoyl-glycerophosphocholine + H2O
stearate + glycerophosphocholine
-
-
-
-
?
1-stearoyl-sn-glycero-3-phosphocholine + H2O
stearic acid + glycerophosphorylcholine
1-stearoyl-sn-glycero-3-phosphoethanolamine + H2O
stearic acid + glycero-3-phosphoethanolamine
2,3-dioleoylglycerol + H2O
?
-
-
-
-
?
2,3-dipalmitoyl-sn-glycero-1-phosphocholine + H2O
monopalmitoyl-sn-glycero-1-phosphocholine + palmitic acid
2-acylglycerophosphocholine + H2O
fatty acid + glycerylphosphocholine
2-acylglycerophosphoethanolamine + H2O
fatty acid + glycerylphosphoethanolamine
-
-
-
-
?
2-acylglycerophosphoglycerol + H2O
fatty acid + glcyerophosphoglycerol
-
-
-
-
?
2-lysophosphatidylcholine + H2O
glycerophosphocholine + a carboxylate
2-lysophosphatidylcholine + H2O
glycerophosphocholine + a fatty acid
-
-
-
?
2-lysophosphatidylcholine + H2O
glycerophosphorylcholine + a carboxylate
-
-
-
-
?
2-palmitoyl-sn-glycero-3-phosphocholine + H2O
palmitic acid + glycero-3-phosphocholine
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
4-nitrophenyl benzoate + H2O
4-nitrophenol + benzoate
-
-
-
-
?
4-nitrophenyl butyrate + H2O
4-nitrophenol + butyrate
4-nitrophenyl caprylate + H2O
4-nitrophenol + caprylate
-
-
-
?
4-nitrophenyl decanoate + H2O
4-nitrophenol + decanoate
-
-
-
-
?
4-nitrophenyl formate + H2O
4-nitrophenol + formate
-
worst substrate
-
-
?
4-nitrophenyl hexanoate + H2O
4-nitrophenol + hexanoate
-
-
-
-
?
4-nitrophenyl laurate + H2O
4-nitrophenol + laurate
4-nitrophenyl myristate + H2O
4-nitrophenol + myristate
4-nitrophenyl palmitate + H2O
4-nitrophenol + palmitate
4-nitrophenyl stearate + H2O
4-nitrophenol + stearate
C10:0-glycero-3-phosphocholine + H2O
?
-
rank order for lysophospholipase activity C12:0-GPC higher than C14:0-GPC, C10:0-GPC higher than C18:0-GPC, C18:1-GPC, and C18:2-GPC higher than C8:0-GPC
-
-
?
C12:0-glycero-3-phosphocholine + H2O
?
-
rank order for lysophospholipase activity C12:0-GPC higher than C14:0-GPC, C10:0-GPC higher than C18:0-GPC, C18:1-GPC, and C18:2-GPC higher than C8:0-GPC
-
-
?
C14:0-glycero-3-phosphocholine + H2O
?
-
rank order for lysophospholipase activity C12:0-GPC higher than C14:0-GPC, C10:0-GPC higher than C18:0-GPC, C18:1-GPC, and C18:2-GPC higher than C8:0-GPC
-
-
?
C18:0-glycero-3-phosphocholine + H2O
?
-
rank order for lysophospholipase activity C12:0-GPC higher than C14:0-GPC, C10:0-GPC higher than C18:0-GPC, C18:1-GPC, and C18:2-GPC higher than C8:0-GPC
-
-
?
C18:1-glycero-3-phosphocholine + H2O
?
-
rank order for lysophospholipase activity C12:0-GPC higher than C14:0-GPC, C10:0-GPC higher than C18:0-GPC, C18:1-GPC, and C18:2-GPC higher than C8:0-GPC
-
-
?
C18:2-glycero-3-phosphocholine + H2O
?
-
rank order for lysophospholipase activity C12:0-GPC higher than C14:0-GPC, C10:0-GPC higher than C18:0-GPC, C18:1-GPC, and C18:2-GPC higher than C8:0-GPC
-
-
?
C8:0-glycero-3-phosphocholine + H2O
?
-
rank order for lysophospholipase activity C12:0-GPC higher than C14:0-GPC, C10:0-GPC higher than C18:0-GPC, C18:1-GPC, and C18:2-GPC higher than C8:0-GPC
-
-
?
dioleoylphosphatidylcholine + H2O
?
-
2% of the activity with dipalmitoylphosphatidylcholine
-
-
?
dioleoylphosphatidylethanolamine + H2O
?
-
11% of the activity with dipalmitoylphosphatidylcholine
-
-
?
dipalmitoylphosphatidylcholine + H2O
?
-
-
-
-
?
egg yolk + H2O
?
W8R447
-
-
-
?
ghrelin + H2O
des-acyl ghrelin + n-octanoic acid
-
-
-
-
?
lysophosphatidylcholine + H2O
glycerophosphorylcholine + a carboxylate
-
lysophospholipase A activity
-
-
?
lysophosphatidylcholine + H2O
glycerophosphorylcholine + unesterified fatty acid
lysophosphatidylcholine + lysophosphatidylcholine
glycerophosphocholine + phosphatidylcholine
lysophosphatidylethanolamine + H2O
?
-
-
-
-
?
lysophosphatidylethanolamine + H2O
fatty acid + glycerylphosphoethanolamine
lysophosphatidylglycerol + H2O
fatty acid + glycerol
-
-
-
-
?
lysophosphatidylinositol + H2O
glycerophosphatidylinositol + a carboxylate
-
78% of activity with 1-palmitoyl-lysophosphatidylcholine
-
?
monooleoylglycerol + H2O
oleic acid + glycerol
-
-
-
-
?
monopalmitoylglycerol + H2O
palmitic acid + glycerol
-
-
-
-
?
p-nitrophenyl acetate + H2O
p-nitrophenol + acetate
p-nitrophenyl butyrate
p-nitrophenol + butyrate
substrate activity assay
-
-
?
p-nitrophenyl palmitate
p-nitrophenol + palmitate
substrate activity assay
-
-
?
palmitoyl-Gialpha1 + H2O
palmitic acid + Gialpha1
-
thioesterase activity
-
?
palmitoyl-glycero-3-phosphocholine + H2O
glycerophosphocholine + palmitic acid
-
-
-
-
?
palmitoyl-peptide + H2O
palmitate + peptide
residue 3 to 14 of RGS4 protein with palmitoyl group attached at Cys12 of RGS4 protein
-
-
?
palmitoyl-SCoA + H2O
HS-CoA + palmitic acid
-
-
-
?
palmitoyllysophosphatidylglycerol + H2O
glycerophosphoglycerol + palmitic acid
-
-
-
-
?
phosphatidic acid + H2O
?
phosphatidylcholine + H2O
lysophosphatidylcholine + a carboxylate
phosphatidylcholine + H2O
lysophosphatidylcholine + glycerophosphorylcholine + a carboxylate
phosphatidylcholine + H2O
lysophosphatidylcholine + glycerophosphorylcholine + a fatty acid
-
-
-
?
phosphatidylethanolamine + H2O
lysophosphatidylethanolamine + glycerophosphorylethanolamine + a carboxylate
phosphatidylethanolamine + H2O
lysophosphatidylethanolamine + glycerophosphorylethanolamine + a fatty acid
-
-
-
?
phosphatidylglycerol + H2O
lysophosphatidylglycerol + a carboxylate
-
94.2% of activity with 1,2-dipalmitoylphosphatidylcholine
-
?
phosphatidylinositol + H2O
lysophophatidylinositol + a carboxylate
phosphatidylinositol + H2O
lysophosphatidylinositol + glycerophosphorylinositol + a carboxylate
phosphatidylserine + H2O
lysophosphatidylserine + glycerophosphorylserine + a carboxylate
phosphatidylserine + H2O
lysophosphatidylserine + glycerophosphorylserine + a fatty acid
-
-
-
?
platelet activating factor + H2O
platelet activating factor + a carboxylate
-
8.9% of activity with 1,2-dipalmitoylphosphatidylcholine
-
?
sphingomyelin + H2O
?
-
3% of the activity with dipalmitoylphosphatidylcholine
-
-
?
triacetin + H2O
?
-
weak activity
-
-
?
tributyrin + H2O
?
-
-
-
-
?
additional information
?
-
1,2,3-trioleoyl-sn-glycerol + H2O
?
-
weak
-
-
?
1,2,3-trioleoyl-sn-glycerol + H2O
?
-
-
-
-
?
1,2-dioctanoyl-sn-glycero-3-phosphocholine + H2O
?
-
-
-
-
?
1,2-dioctanoyl-sn-glycero-3-phosphocholine + H2O
?
-
-
-
-
?
1,2-dipalmitoyl-sn-glycero-3-phosphocholine + H2O
?
-
-
-
-
?
1,2-dipalmitoyl-sn-glycero-3-phosphocholine + H2O
?
-
-
-
-
?
1,2-dipalmitoyl-sn-glycero-3-phosphocholine + H2O
?
-
-
-
?
1,2-dipalmitoylphosphatidylcholine + H2O
?
-
-
-
-
?
1,2-dipalmitoylphosphatidylcholine + H2O
?
-
-
-
?
1-acyl-sn-glycero-3-phospho-myo-inositol
fatty acid + glycero-3-phospho-myo-inositol
-
weak
-
-
?
1-acyl-sn-glycero-3-phospho-myo-inositol
fatty acid + glycero-3-phospho-myo-inositol
-
-
-
-
?
1-acyl-sn-glycero-3-phosphocholine + H2O
fatty acid + glycero-3-phosphocholine
-
-
-
?
1-acyl-sn-glycero-3-phosphocholine + H2O
fatty acid + glycero-3-phosphocholine
-
-
-
-
?
1-acyl-sn-glycero-3-phosphocholine + H2O
fatty acid + glycero-3-phosphocholine
-
-
-
-
?
1-acyl-sn-glycero-3-phosphocholine + H2O
fatty acid + glycero-3-phosphocholine
-
-
-
-
?
1-acyl-sn-glycero-3-phosphoserine + H2O
fatty acid + glycerophosphoserine
-
-
-
-
?
1-acyl-sn-glycero-3-phosphoserine + H2O
fatty acid + glycerophosphoserine
-
-
-
-
?
1-acyl-sn-glycero-3-phosphoserine + H2O
fatty acid + glycerophosphoserine
-
-
-
-
?
1-acylglycerophosphoethanolamine + H2O
fatty acid + glycerylphosphoethanolamine
-
-
-
-
?
1-acylglycerophosphoethanolamine + H2O
fatty acid + glycerylphosphoethanolamine
-
-
-
-
?
1-oleoyl-sn-glycero-3-phosphocholine + H2O
oleic acid + glycerophosphorylcholine
-
-
-
-
?
1-oleoyl-sn-glycero-3-phosphocholine + H2O
oleic acid + glycerophosphorylcholine
-
-
-
-
?
1-oleoyl-sn-glycero-3-phosphocholine + H2O
oleic acid + glycerophosphorylcholine
-
-
-
-
?
1-oleoyl-sn-glycero-3-phosphoethanolamine + H2O
oleic acid + glycero-3-phosphoethanolamine
-
-
-
-
?
1-oleoyl-sn-glycero-3-phosphoethanolamine + H2O
oleic acid + glycero-3-phosphoethanolamine
-
-
-
-
?
1-oleoyl-sn-glycero-3-phosphoethanolamine + H2O
oleic acid + glycero-3-phosphoethanolamine
-
weak
-
-
?
1-oleoyl-sn-glycero-3-phosphoethanolamine + H2O
oleic acid + glycero-3-phosphoethanolamine
-
-
-
-
?
1-palmitoyl lysophosphatidylcholine + H2O
glycerophosphocholine + palmitate
-
preferred substrate, LPL1
-
-
?
1-palmitoyl lysophosphatidylcholine + H2O
glycerophosphocholine + palmitate
-
-
-
?
1-palmitoyl-2-acetyl-sn-glycero-3-phosphocholine + H2O
?
-
-
-
-
?
1-palmitoyl-2-acetyl-sn-glycero-3-phosphocholine + H2O
?
-
-
-
-
?
1-palmitoyl-2-lysophosphatidylcholine + H2O
?
-
-
-
?
1-palmitoyl-2-lysophosphatidylcholine + H2O
?
-
-
-
-
?
1-palmitoyl-2-lysophosphatidylcholine + H2O
glycerophosphocholine + palmitic acid
-
-
-
-
?
1-palmitoyl-2-lysophosphatidylcholine + H2O
glycerophosphocholine + palmitic acid
-
-
-
?
1-palmitoyl-lysophosphatidylcholine + H2O
glycerophosphocholine + palmitic acid
-
-
-
?
1-palmitoyl-lysophosphatidylcholine + H2O
glycerophosphocholine + palmitic acid
-
-
-
-
?
1-palmitoyl-lysophosphatidylcholine + H2O
glycerophosphocholine + palmitic acid
-
-
-
?
1-palmitoyl-lysophosphatidylethanolamine + H2O
glycerophosphatidylethanolamine + palmitic acid
-
as active as 1-palmitoyl lysophosphatidylcholine at pH 7.0
-
-
?
1-palmitoyl-lysophosphatidylethanolamine + H2O
glycerophosphatidylethanolamine + palmitic acid
-
29% of activity with 1-palmitoyl-lysophosphatidylcholine
-
?
1-palmitoyl-sn-glycero-3-phosphocholine + H2O
palmitic acid + glycero-3-phosphocholine
-
-
-
?
1-palmitoyl-sn-glycero-3-phosphocholine + H2O
palmitic acid + glycero-3-phosphocholine
-
-
-
-
?
1-palmitoyl-sn-glycero-3-phosphocholine + H2O
palmitic acid + glycero-3-phosphocholine
-
-
-
-
?
1-palmitoyl-sn-glycero-3-phosphocholine + H2O
palmitic acid + glycero-3-phosphocholine
-
-
-
-
?
1-palmitoyl-sn-glycero-3-phosphocholine + H2O
palmitic acid + glycero-3-phosphocholine
-
-
-
-
?
1-palmitoyl-sn-glycero-3-phosphocholine + H2O
palmitic acid + glycero-3-phosphocholine
-
-
-
-
?
1-palmitoyl-sn-glycero-3-phosphocholine + H2O
palmitic acid + glycero-3-phosphocholine
-
-
-
-
?
1-palmitoyl-sn-glycero-3-phosphocholine + H2O
palmitic acid + glycero-3-phosphocholine
-
-
-
?
1-palmitoyl-sn-glycero-3-phosphoethanolamine + H2O
palmitic acid + glycero-3-phosphoethanolamine
-
-
-
-
?
1-palmitoyl-sn-glycero-3-phosphoethanolamine + H2O
palmitic acid + glycero-3-phosphoethanolamine
-
-
-
-
?
1-palmitoyl-sn-glycero-3-phosphoethanolamine + H2O
palmitic acid + glycero-3-phosphoethanolamine
-
-
-
-
?
1-palmitoyl-sn-glycero-3-phosphoethanolamine + H2O
palmitic acid + glycero-3-phosphoethanolamine
-
weak
-
-
?
1-palmitoyl-sn-glycero-3-phosphoethanolamine + H2O
palmitic acid + glycero-3-phosphoethanolamine
-
-
-
-
?
1-palmitoyl-sn-glycero-3-phosphoserine + H2O
glycerophosphoserine + palmitic acid
-
as active as 1-palmitoyl lysophosphatidylcholine at pH 7.0, 70% of the activity with 1-palmitoyl lysophosphatidylcholine at pH 5.0
-
-
?
1-palmitoyl-sn-glycero-3-phosphoserine + H2O
glycerophosphoserine + palmitic acid
-
3.8% of activity with 1-palmitoyl-lysophosphatidylcholine
-
?
1-stearoyl-sn-glycero-3-phosphocholine + H2O
stearic acid + glycerophosphorylcholine
-
-
-
-
?
1-stearoyl-sn-glycero-3-phosphocholine + H2O
stearic acid + glycerophosphorylcholine
-
-
-
-
?
1-stearoyl-sn-glycero-3-phosphoethanolamine + H2O
stearic acid + glycero-3-phosphoethanolamine
-
-
-
-
?
1-stearoyl-sn-glycero-3-phosphoethanolamine + H2O
stearic acid + glycero-3-phosphoethanolamine
-
-
-
-
?
1-stearoyl-sn-glycero-3-phosphoethanolamine + H2O
stearic acid + glycero-3-phosphoethanolamine
-
-
-
-
?
2,3-dipalmitoyl-sn-glycero-1-phosphocholine + H2O
monopalmitoyl-sn-glycero-1-phosphocholine + palmitic acid
-
-
-
?
2,3-dipalmitoyl-sn-glycero-1-phosphocholine + H2O
monopalmitoyl-sn-glycero-1-phosphocholine + palmitic acid
-
-
-
-
?
2-acylglycerophosphocholine + H2O
fatty acid + glycerylphosphocholine
-
-
-
-
?
2-acylglycerophosphocholine + H2O
fatty acid + glycerylphosphocholine
-
2-acyl-sn-glycero-3-phosphocholine
-
-
?
2-lysophosphatidylcholine + H2O
glycerophosphocholine + a carboxylate
-
-
-
-
?
2-lysophosphatidylcholine + H2O
glycerophosphocholine + a carboxylate
-
-
-
-
?
2-lysophosphatidylcholine + H2O
glycerophosphocholine + a carboxylate
-
-
-
?
2-lysophosphatidylcholine + H2O
glycerophosphocholine + a carboxylate
-
-
?
2-lysophosphatidylcholine + H2O
glycerophosphocholine + a carboxylate
enzyme has also lysophospholipase transcylase activity
-
?
2-lysophosphatidylcholine + H2O
glycerophosphocholine + a carboxylate
-
-
-
?
2-lysophosphatidylcholine + H2O
glycerophosphocholine + a carboxylate
-
-
-
-
?
2-lysophosphatidylcholine + H2O
glycerophosphocholine + a carboxylate
-
-
-
?
2-lysophosphatidylcholine + H2O
glycerophosphocholine + a carboxylate
-
-
-
?
2-lysophosphatidylcholine + H2O
glycerophosphocholine + a carboxylate
-
-
?
2-lysophosphatidylcholine + H2O
glycerophosphocholine + a carboxylate
-
-
?
2-lysophosphatidylcholine + H2O
glycerophosphocholine + a carboxylate
-
-
-
?
2-lysophosphatidylcholine + H2O
glycerophosphocholine + a carboxylate
-
-
-
?
2-lysophosphatidylcholine + H2O
glycerophosphocholine + a carboxylate
-
-
-
?
2-lysophosphatidylcholine + H2O
glycerophosphocholine + a carboxylate
W8R447
-
-
-
?
2-lysophosphatidylcholine + H2O
glycerophosphocholine + a carboxylate
-
-
-
?
2-lysophosphatidylcholine + H2O
glycerophosphocholine + a carboxylate
-
-
-
?
2-lysophosphatidylcholine + H2O
glycerophosphocholine + a carboxylate
-
-
-
-
?
2-lysophosphatidylcholine + H2O
glycerophosphocholine + a carboxylate
-
-
-
-
?
2-lysophosphatidylcholine + H2O
glycerophosphocholine + a carboxylate
-
-
-
-
?
2-lysophosphatidylcholine + H2O
glycerophosphocholine + a carboxylate
-
-
-
?
2-palmitoyl-sn-glycero-3-phosphocholine + H2O
palmitic acid + glycero-3-phosphocholine
-
-
-
-
?
2-palmitoyl-sn-glycero-3-phosphocholine + H2O
palmitic acid + glycero-3-phosphocholine
-
-
-
-
?
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
-
-
-
-
?
4-nitrophenyl acetate + H2O
4-nitrophenol + acetate
-
-
-
-
?
4-nitrophenyl butyrate + H2O
4-nitrophenol + butyrate
-
-
-
-
?
4-nitrophenyl butyrate + H2O
4-nitrophenol + butyrate
-
-
-
-
?
4-nitrophenyl butyrate + H2O
4-nitrophenol + butyrate
-
-
-
-
?
4-nitrophenyl butyrate + H2O
4-nitrophenol + butyrate
-
6.84% activity compared to 4-nitrophenyl palmitate
-
-
?
4-nitrophenyl butyrate + H2O
4-nitrophenol + butyrate
relative activity: 0.45%
-
-
?
4-nitrophenyl butyrate + H2O
4-nitrophenol + butyrate
best substrate
-
-
?
4-nitrophenyl laurate + H2O
4-nitrophenol + laurate
-
23.21% activity compared to 4-nitrophenyl palmitate
-
-
?
4-nitrophenyl laurate + H2O
4-nitrophenol + laurate
relative activity: 7.56%
-
-
?
4-nitrophenyl myristate + H2O
4-nitrophenol + myristate
-
best substrate
-
-
?
4-nitrophenyl myristate + H2O
4-nitrophenol + myristate
-
-
-
-
?
4-nitrophenyl myristate + H2O
4-nitrophenol + myristate
-
-
-
-
?
4-nitrophenyl myristate + H2O
4-nitrophenol + myristate
-
58.61% activity compared to 4-nitrophenyl palmitate
-
-
?
4-nitrophenyl myristate + H2O
4-nitrophenol + myristate
relative activity: 12.77%
-
-
?
4-nitrophenyl palmitate + H2O
4-nitrophenol + palmitate
-
-
-
-
?
4-nitrophenyl palmitate + H2O
4-nitrophenol + palmitate
-
best substrate
-
-
?
4-nitrophenyl palmitate + H2O
4-nitrophenol + palmitate
-
best substrate
-
-
?
4-nitrophenyl palmitate + H2O
4-nitrophenol + palmitate
-
100% activity
-
-
?
4-nitrophenyl palmitate + H2O
4-nitrophenol + palmitate
relative activity: 100%
-
-
?
4-nitrophenyl palmitate + H2O
4-nitrophenol + palmitate
worst substrate
-
-
?
4-nitrophenyl stearate + H2O
4-nitrophenol + stearate
-
worst substrate
-
-
?
4-nitrophenyl stearate + H2O
4-nitrophenol + stearate
-
second best substrate
-
-
?
4-nitrophenyl stearate + H2O
4-nitrophenol + stearate
-
second best substrate
-
-
?
4-nitrophenyl stearate + H2O
4-nitrophenol + stearate
relative activity: 56.69%
-
-
?
lysophosphatidylcholine + H2O
glycerophosphorylcholine + unesterified fatty acid
-
-
-
-
?
lysophosphatidylcholine + H2O
glycerophosphorylcholine + unesterified fatty acid
-
-
-
-
?
lysophosphatidylcholine + H2O
glycerophosphorylcholine + unesterified fatty acid
-
-
-
-
?
lysophosphatidylcholine + H2O
glycerophosphorylcholine + unesterified fatty acid
-
myristoyllysophosphatidylcholine is hydrolyzed 50% better than the longer chain palmitoyllysophosphatidylcholine
-
-
?
lysophosphatidylcholine + H2O
glycerophosphorylcholine + unesterified fatty acid
-
-
-
?
lysophosphatidylcholine + H2O
glycerophosphorylcholine + unesterified fatty acid
-
-
-
-
?
lysophosphatidylcholine + H2O
glycerophosphorylcholine + unesterified fatty acid
-
-
-
-
?
lysophosphatidylcholine + H2O
glycerophosphorylcholine + unesterified fatty acid
-
-
glycerophosphocholine + fatty acid
?
lysophosphatidylcholine + H2O
glycerophosphorylcholine + unesterified fatty acid
-
-
-
?
lysophosphatidylcholine + H2O
glycerophosphorylcholine + unesterified fatty acid
-
-
-
-
?
lysophosphatidylcholine + H2O
glycerophosphorylcholine + unesterified fatty acid
-
249% of the activity with phosphatidylcholine
-
?
lysophosphatidylcholine + lysophosphatidylcholine
glycerophosphocholine + phosphatidylcholine
-
-
-
?
lysophosphatidylcholine + lysophosphatidylcholine
glycerophosphocholine + phosphatidylcholine
-
-
-
?
lysophosphatidylcholine + lysophosphatidylcholine
glycerophosphocholine + phosphatidylcholine
-
slight preference for palmitate over stearate and laurate to be incorporated into phosphatidylcholine. No preference for palmitate over myristate
-
?
lysophosphatidylethanolamine + H2O
fatty acid + glycerylphosphoethanolamine
-
-
-
?
lysophosphatidylethanolamine + H2O
fatty acid + glycerylphosphoethanolamine
-
27% of the activity with phosphatidylcholine
-
-
?
p-nitrophenyl acetate + H2O
p-nitrophenol + acetate
-
-
-
-
?
p-nitrophenyl acetate + H2O
p-nitrophenol + acetate
substrate activity assay
-
-
?
p-nitrophenyl acetate + H2O
p-nitrophenol + acetate
-
no activity detectable
-
-
?
phosphatidic acid + H2O
?
-
-
-
?
phosphatidic acid + H2O
?
-
62% of the activity with phosphatidylcholine
-
-
?
phosphatidylcholine + H2O
lysophosphatidylcholine + a carboxylate
-
-
-
?
phosphatidylcholine + H2O
lysophosphatidylcholine + a carboxylate
-
-
?
phosphatidylcholine + H2O
lysophosphatidylcholine + glycerophosphorylcholine + a carboxylate
-
-
-
-
?
phosphatidylcholine + H2O
lysophosphatidylcholine + glycerophosphorylcholine + a carboxylate
-
-
-
?
phosphatidylcholine + H2O
lysophosphatidylcholine + glycerophosphorylcholine + a carboxylate
-
-
-
-
?
phosphatidylcholine + H2O
lysophosphatidylcholine + glycerophosphorylcholine + a carboxylate
-
hydrolysis of the 1-acly ester bond and the 2-acyl ester bond, phospholipase B activity
-
-
?
phosphatidylcholine + H2O
lysophosphatidylcholine + glycerophosphorylcholine + a carboxylate
-
-
-
-
?
phosphatidylcholine + H2O
lysophosphatidylcholine + glycerophosphorylcholine + a carboxylate
-
phospholipase B activity, hydrolyzes the acyl ester bonds sequentially, first the 2-acyl group and then the 1-acyl group
-
-
?
phosphatidylcholine + H2O
lysophosphatidylcholine + glycerophosphorylcholine + a carboxylate
-
-
-
-
?
phosphatidylethanolamine + H2O
lysophosphatidylethanolamine + glycerophosphorylethanolamine + a carboxylate
-
-
-
-
?
phosphatidylethanolamine + H2O
lysophosphatidylethanolamine + glycerophosphorylethanolamine + a carboxylate
-
hydrolysis and acyl transfer
-
-
?
phosphatidylethanolamine + H2O
lysophosphatidylethanolamine + glycerophosphorylethanolamine + a carboxylate
-
-
-
-
?
phosphatidylinositol + H2O
lysophophatidylinositol + a carboxylate
-
15.6% of activity with 1,2-dipalmitoylphosphatidylcholine
-
?
phosphatidylinositol + H2O
lysophophatidylinositol + a carboxylate
-
-
-
?
phosphatidylinositol + H2O
lysophosphatidylinositol + glycerophosphorylinositol + a carboxylate
-
-
-
-
?
phosphatidylinositol + H2O
lysophosphatidylinositol + glycerophosphorylinositol + a carboxylate
-
-
-
-
?
phosphatidylinositol + H2O
lysophosphatidylinositol + glycerophosphorylinositol + a carboxylate
-
819% of the activity with phosphatidylcholine
-
-
?
phosphatidylserine + H2O
lysophosphatidylserine + glycerophosphorylserine + a carboxylate
-
-
-
-
?
phosphatidylserine + H2O
lysophosphatidylserine + glycerophosphorylserine + a carboxylate
-
-
-
-
?
phosphatidylserine + H2O
lysophosphatidylserine + glycerophosphorylserine + a carboxylate
-
22% of the activity with phosphatidylcholine
-
-
?
additional information
?
-
-
acyl-CoA-binding protein 2 can bind both lysophosphatidylcholine and lysophospholipase 2 to promote the degradation of lysophosphatidylcholine in response to Cd2+-induced oxidative stress
-
-
?
additional information
?
-
-
LipC cleaves both ester linkages of the sn-1 and sn-2 positions of phospholipids (phospholipase B activity)
-
-
?
additional information
?
-
-
no activity with tributyrin, tricaprilin or triolein
-
-
?
additional information
?
-
-
PLB1 shows phospholipase B activity, lysophospholipase activity and transacylase activity
-
-
?
additional information
?
-
-
the LPL1 protein only possesses lysophospholipase and transacylase activity
-
-
?
additional information
?
-
-
the LPL1 protein only possesses lysophospholipase and transacylase activity
-
-
?
additional information
?
-
phospholipase B is necessary for the initiation of pulmonary infection by Cryptpococcus neoformans and for dissemination from the lung via the lymphatics. PLB1 plays a role in the binding of Cryptpococcus neoformans to host lung epithelial cells, possibly due to production of fatty acids from plasma memrane and/or surfactant by PLB activity
-
-
?
additional information
?
-
-
phospholipase B is necessary for the initiation of pulmonary infection by Cryptpococcus neoformans and for dissemination from the lung via the lymphatics. PLB1 plays a role in the binding of Cryptpococcus neoformans to host lung epithelial cells, possibly due to production of fatty acids from plasma memrane and/or surfactant by PLB activity
-
-
?
additional information
?
-
-
phospholipase B1 is implicated in transcellular metabolism of macrophage-derived lipids. During both logarithmic and stationary phases of growth, the physiologically relevant phospholipids, dipalmitoyl phosphatidylcholine (DPPC) and dioleoyl phosphatidylcholine, are taken up and metabolized via PLB1
-
-
?
additional information
?
-
substrate specificities of Escherichia coli thioesterase I/protease I/lysophospholipase L1 are governed by its switch loop movement
-
-
?
additional information
?
-
-
substrate specificities of Escherichia coli thioesterase I/protease I/lysophospholipase L1 are governed by its switch loop movement
-
-
?
additional information
?
-
combined activities of secretory phospholipases and eosinophil lysophospholipases induce pulmonary surfactant dysfunction by phospholipid hydrolysis
-
-
?
additional information
?
-
-
human 60-kDa lysophospholipase contains an N-terminal L-asparaginase domain that is allosterically regulated by L-asparagine
-
-
?
additional information
?
-
-
the function of the enzyme is directed to the disposal of the starch inclusion lipids during their release from the starch matrix during germination
-
-
?
additional information
?
-
-
lysophospholipase activity of lysophosphatidylcholine/transacylase is smaller than the transacylase activity
-
-
?
additional information
?
-
-
global regulatory proteins LetA and RpoS control lysophospholipase A
-
-
?
additional information
?
-
-
enzyme encoded by the gene plaB is a phospholipase A and a lysophospholipase A
-
-
?
additional information
?
-
-
global regulatory proteins LetA and RpoS control lysophospholipase A
-
-
?
additional information
?
-
-
loss of lysophospholipase 3 increases atherosclerosis in apolipoprotein E-deficient mice. Even in a severe model of atherosclerosis, LCAT-like lysophospholipase exhibits a protective effect on atheroma formation at all stages and throughout the aortic tree in mice fed on normal diet
-
-
?
additional information
?
-
-
combined activities of secretory phospholipases and eosinophil lysophospholipases induce pulmonary surfactant dysfunction by phospholipid hydrolysis
-
-
?
additional information
?
-
-
hydrolyzes sn-1 esters in lysophosphatidylcholine and lysophosphatidic acid
-
-
?
additional information
?
-
-
no transacylase activity
-
-
?
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
1,12-bis(tributylammonium)dodecane
-
-
1,12-bis(trihexylammonium)dodecane
-
-
1,12-bis(triisopentylammonium)dodecane
-
-
1,12-bis(tripentylammonium)dodecane
-
-
1,12-bis(tripropylammonium)dodecane
-
-
1-palmitoyl lysophosphatidylcholine
competitive inhibitor for acylprotein thioesterase activity
1-stearoyl-2-arachidonoyl-sn-glycero-3-phosphate
2-Hydroxy-5-nitrobenzyl bromide
-
-
3(cis,cis-7,10)hexadecadienyl-4-hydroxy-2-butenolide
-
-
AACOCF3
-
a trifluoromethyl ketone analog of arachidonic acid, uncompetitive
alexidine
-
specific inhibitor, 66% inhibition at 0.00025 mM
arachidonyl trifluoromethyl ketone
-
0.025 mM, approx. 50% inhibition
bis(p-nitrophenyl)phosphate
-
0.01 mM, 8% inhibition of lysophospholipase I and 61% inhibition of lysophospholipase II
bromoenol lactone
-
0.025 mM, approx. 30% inhibition
CaCl2
-
10 mM, 22% inhibition of phospholipase B activity, slight activation of lysophospholipase activity
calcium dipicolinate
-
71% residual activity at 1 mM
carnitine
-
10 mM, 38% inhibition of phospholipase B activity; 10 mM, 9% inhibition at pH 7.0, LPL1
cetyltrimethylammonium bromide
-
-
chlorpromazine
-
at low concentrations significantly stimulates phospholipase B activity of native enzyme, strong stimulation at high concentrations
chlorpyrifos pentyl oxon
-
0.000076 mM, 50% inhibition
D-alanine
-
94% residual activity at 1 mM
dichlorvos
-
0.000028 mM, 50% inhibition
diisopropylfluorophosphate
dipalmitoyl phosphatidylcholine
-
0.5 mM, 84% inhibition at pH 5.0, 50% inhibition at pH 7.0, LPL 1
dipalmitoylphosphatidylcholine
-
0.5 mM, 89% inhibition of lysophospholipase at pH 5.0, 82% inhibition of lysophospholipase at pH 7.0
diphenyl fluorophosphinate
-
2 mM, 52% inhibition
dipicolinate
-
82% residual activity at 1 mM
DNA containing thymine glycol
-
EGTA
-
10 mM, 15% inhibition at pH 7.0, LPL1
EPTC sulfoxide
-
0.2 mM, 51% inhibition
ethyl octylphosphonofluoridate
FeCl3
-
10 mM, 39% inhibition at pH 5.0, 38% inhibition at pH 7.0, LPL1; 10 mM, 80% inhibiotion of phospholipase B activity, 17% inhibition of lysophospholipase activity at pH 5.0, 29% in inhibition of lysophospholipase activity at pH 7.0
glutathione
-
membrane-bound enzyme, no inhibition of the soluble enzyme
Insulin
-
insulin reduces NRE mRNA levels in a dose-dependent manner in 3T3-L1 adipocytes
-
isopropyl dodecylphosphonofluoridate
L-alanine
-
93% residual activity at 1 mM
methyl (5Z,8Z,11Z,14Z)-icosa-5,8,11,14- tetraenylphosphonofluoridate
-
-
n-dodecyl-benzodioxaphosphorine 2-oxide
n-octadecyl-benzodioxaphosphorine 2-oxide
-
0.000067 mM, 50% inhibition
p-hydroxymercuribenzoate
-
-
palmitoyl carnitine
-
0.5 mM, 90% inhibition at pH 5.0, LPL1; 1 mM, 64% inhibition of phospholipase B activity, 65% inhibition of lysophospholipase activity at pH 5.0
palmitoyl-peptide
competitive inhibitor for lysophospholipase activity
phenyl N-benzylcarbamate
-
0.2 mM, 47% inhibition
phenylmethylsulfonyl fluoride
S-n-octyl-benzodioxaphosphorine 2-oxide
-
0.000005 mM, 50% inhibition
sphingomyelin
-
0.5 MM, 21% inhibition at pH 5.0, 29% inhibition at pH 7.0, LPL1; 0.5 mM, 35% inhibition of phospholipase B activity, 45% inhibition of lysophospholipase at pH 5.0, 28% inhibition of lysophospholipase at pH 7.0
sulfite
-
enzymatic activity: 1.6%
tellurate
-
enzymatic activity: 19.8%
tellurite
-
enzymatic activity: 0%
tri-o-cresyl phosphate
TOCP
tricyclodecan-9-yl-xanthogenate potassium
-
-
trifluoromethyl ketone
-
0.025 mM, approx. 40% inhibition
1-stearoyl-2-arachidonoyl-sn-glycero-3-phosphate
-
-
1-stearoyl-2-arachidonoyl-sn-glycero-3-phosphate
-
-
Al3+
-
-
Ca2+
-
40% residual activity at 1 mM
Ca2+
-
CaCl2, reversed by EDTA
Ca2+
-
about 90% residual activity at 10 mM
Cu2+
-
little effect
Cu2+
-
less than 5% residual activity at 10 mM
Cu2+
the enzyme is inhibited by 5 mM Cu2+
deoxycholate
-
soluble enzyme
deoxycholate
-
0.1% sodium deoxycholate, complete inhibition of lysophospholipase activity
diisopropylfluorophosphate
-
-
diisopropylfluorophosphate
-
-
diisopropylfluorophosphate
-
-
dithiothreitol
-
78% residual activity at 5 mM
dithiothreitol
-
10 mM, 9% inhibition at pH 7.0, LPL1
dithiothreitol
-
10 mM, 50% inhibition of phospholipase activity
DNA containing thymine glycol
-
-
-
DNA containing thymine glycol
-
inhibits activity with ghrelin and with palmitoyllysophosphatidylglycerol
-
EDTA
-
81% residual activity at 5 mM
ethyl octylphosphonofluoridate
-
0.0000018 mM, 50% inhibition
ethyl octylphosphonofluoridate
-
0.00009 mM, 50% inhibition
Fe2+
-
-
Fe2+
-
about 30% residual activity at 10 mM
Fe3+
-
1 mM, 95% inhibition of phospholipase activity, 80% inhibition of lysophospholipase activity
Hg2+
-
-
Hg2+
-
61% residual activity at 1 mM
Hg2+
-
5 mM, inhibits phospholipase B activity by 67%, no inhibition of lysophospholipase activity
Hg2+
-
less than 2% residual activity at 10 mM
iodoacetamide
-
-
isopropyl dodecylphosphonofluoridate
-
0.000002 mM, 50% inhibition
isopropyl dodecylphosphonofluoridate
-
0.0000067 mM, 50% inhibition
L-palmitoylcarnitine
-
inhibits phosphatidylcholine formation
lysophosphatidic acid
-
inhibition in a dose-dependent manner
lysophosphatidic acid
-
-
lysophosphatidic acid
-
-
Mg2+
-
-
Mg2+
-
MgCl2, reversed by EDTA
Mg2+
-
about 75% residual activity at 10 mM
Mn2+
-
67% residual activity at 1 mM
Mn2+
-
about 95% residual activity at 10 mM
n-dodecyl-benzodioxaphosphorine 2-oxide
-
0.000008 mM, 50% inhibition
n-dodecyl-benzodioxaphosphorine 2-oxide
-
0.000034 mM, 50% inhibition
NEM
-
soluble enzyme, no inhibition of the membrane-bound enzyme
NEM
-
transacylase activity
palmitoylcarnitine
-
transacylase activity
palmitoylcarnitine
-
10 mM, 70% inhibition of phospholipase activity
phenylmethylsulfonyl fluoride
-
72% residual activity at 1 mM
phenylmethylsulfonyl fluoride
PMSF
phenylmethylsulfonyl fluoride
PMSF
phosphatidic acid
-
0.5 mM, 24% inhibition at pH 5.0, 66% inhibition at pH 7.0, LPL1; 0.5 mM, 58% inhibition of phospholipase B activity, 92% inhibition of lysophospholipase at pH 5.0, 87% inhibition of lysophospholipase at pH 7.0
SDS
-
soluble and membrane-bound enzyme
SDS
-
0.05%, complete inhibition of phospholipase activity
Triton X-100
-
soluble enzyme
Triton X-100
-
0.1 w/v, 48% inhibition at pH 5.0, LPL1; 0.1% w/v, 85% inhibition of phospholipase B activity, 91% inhibition of lysophospholipase B activity at pH 5.0, 95% inhibition of lysophospholipase B activity at pH 7.0
Triton X-100
-
50% inhibition of lysophospholipase activity
Triton X-100
-
monomolecular and micellar form of Triton X-100
Zn2+
-
-
Zn2+
-
84% residual activity at 1 mM
Zn2+
-
about 25% residual activity at 10 mM
Zn2+
the enzyme is inhibited by 5 mM Zn2+
additional information
the enzyme cannot be inhibited by 5 mM EDTA
-
additional information
-
the addition of EDTA alone had no effect on the lipase activity
-
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Oishi, H.; Tsuda, S.; Watanabe, Y.; Tamai, Y.
Purification and some properties of phospholipase B from Schizosaccharomyces pombe
Biosci. Biotechnol. Biochem.
60
1087-1092
1996
Schizosaccharomyces pombe
brenda
Witt, W.; Schweingruber, M.E.; Mertsching, A.
Phospholipase B from the plasma membrane of Saccharomyces cerevisiae
Biochim. Biophys. Acta
795
108-116
1984
Saccharomyces cerevisiae
brenda
Takeuchi, Y.
Interaction of Penicillium notatum phospholipase B with divalent cations
Biochim. Biophys. Acta
960
157-163
1988
Penicillium chrysogenum
brenda
Oishi, H.; Morimoto, T.; Watanabe, Y.; Tamai, Y.
Purification and characterization of phospholipase B from Kluyveromyces lactis, and cloning of phospholipase B gene
Biosci. Biotechnol. Biochem.
63
83-90
1999
Kluyveromyces lactis (O59863), Kluyveromyces lactis
brenda
Takeuchi, Y.; Okumura, T.; Sugatani, J.; Saito, K.
Molecular relationship between two types of phospholipase B from Penicillium notatum and reconstitution of active enzyme from its peptide fragments
Arch. Biochem. Biophys.
252
206-217
1987
Penicillium chrysogenum
brenda
Fujikura, Y.; Baisted, D.
Purification and characterization of a basic lysophospholipase in germinating barley
Arch. Biochem. Biophys.
243
570-578
1985
Hordeum vulgare
brenda
Karasawa, K.; Kudo, I.; Kobayashi, T.; Sa-Eki, T.; Inoue, K.; Nojima, S.
Purification and characterization of lysophospholipase L2 of Escherichia coli K-12
J. Biochem.
98
1117-1125
1985
Escherichia coli
brenda
Ichimasa, M.; Shiobara, M.
Purification and some properties of soluble phospholipase B from baker's yeast (Saccharomyces cerevisiae)
Agric. Biol. Chem.
49
1083-1089
1985
Saccharomyces cerevisiae
-
brenda
Jarvis, A.A.; Cain, C.; Dennis, E.A.
Purification and characterization of a lysophospholipase from human amniotic membranes
J. Biol. Chem.
259
15188-15195
1984
Homo sapiens
brenda
Ichimasa, M.; Morooka, T.; Niimura, T.
Purification and properties of a membrane-bound phospholipase B from baker's yeast (Saccharomyces cerevisiae)
J. Biochem.
95
137-145
1984
Saccharomyces cerevisiae
brenda
Gross, R.W.; Sobel, B.E.
Rabbit myocardial cytosolic lysophospholipase. Purification, characterization, and competitive inhibition by L-palmitoyl carnitine
J. Biol. Chem.
258
5221-5226
1983
Oryctolagus cuniculus
brenda
Baisted, D.J.; Stroud, F.
Soluble and particulate lysophospholipase in the aleurone and endosperm of germinating barley
Phytochemistry
21
29-31
1982
Hordeum vulgare
-
brenda
Van den Bosch, H.; Vianen, G.M.; van Heusden, G.P.H.
Lysophospholipase-transacylase from rat lung
Methods Enzymol.
71
513-521
1981
Rattus norvegicus
brenda
Sugatani, J.; Okumura, T.; Saito, K.
Studies of a phospholipase B from Penicillium notatum. Substrate specificity and properties of active site
Biochim. Biophys. Acta
620
372-386
1980
Penicillium chrysogenum
brenda
Sugatani, J.; Kawasaki, N.; Saito, K.
Studies on a phospholipase B from Penicillium notatum. Substrate specificity
Biochim. Biophys. Acta
529
29-37
1978
Penicillium chrysogenum
brenda
Victoria, E.J.; Korn, E.D.
Plasma membrane and soluble lysophospholipases of Acanthamoeba castellanii
Arch. Biochem. Biophys.
171
255-258
1975
Acanthamoeba castellanii
brenda
Doi, O.; Nojima, S.
Lysophospholipase of Escherichia coli
J. Biol. Chem.
250
5208-5214
1975
Escherichia coli
brenda
Van den Bosch, H.; Aarsman, A.J.; de Jong, J.G.; van Deenen, L.L.M.
Studies on lysophospholipases. I. Purification and some properties of a lysophospholipase from beef pancreas
Biochim. Biophys. Acta
296
94-104
1973
Bos taurus
brenda
De Jong, J.G.N.; van den Bosch, H.; Aarsman, A.J.; van Deenen, L.L.M.
Studies on lysophospholipases. II. Substrate specificity of a lysolecithin hydrolyzing carboxylesterase from beef pancreas
Biochim. Biophys. Acta
296
105-115
1973
Bos taurus
brenda
Kawasaki, N.; Saito, K.
Purification and some properties of lysophospholipase from Penicillium notatum
Biochim. Biophys. Acta
296
426-430
1973
Penicillium chrysogenum
brenda
Maeda, S
Kashiwabara, Y.: Purification and properties of a membrane-bound phospholipase B from Mycobacterium lepraemurium
Biochim. Biophys. Acta
1303
31-38
1996
Mycobacterium lepraemurium
brenda
Tojo, H.; Ichida, T.; Okamoto, M.
Purification and characterization of a catalytic domain of rat intestinal phospholipase B/lipase associated with brush border membranes
J. Biol. Chem.
273
2214-2221
1998
Rattus norvegicus
brenda
De Jong, J.G.N.; van den Bosch, H.; Rijken, D.; van Deenen, L.L.M.
Studies on lysophospholipases. III. The complete purification of two proteins with lysophospholipase activity from beef liver
Biochim. Biophys. Acta
369
50-63
1974
Bos taurus
brenda
Sugimoto, H.; Hayashi, H.; Yamashita, S.
Purification, cDNA cloning, and regulation of lysophospholipase from rat liver
J. Biol. Chem.
271
7705-7711
1996
Rattus norvegicus
brenda
Mirbod, F.; Banno, Y.; Ghannoum, M.A.; Ibrahim, A.S.; Nakashima, S.; Kitajima, Y.; Cole, G.T.; Nozawa, Y.
Purification and characterization of lysophospholipase-transacylase (h-LPTA) from a highly virulant strain of Candida albicans
Biochim. Biophys. Acta
1257
181-188
1995
Candida albicans
brenda
Wang, A.; Hsiu-Chiung, Y.; Friedman, P.; Johnson, C.A.; Dennis, E.A.
A specific human lysophospholipase: cDNA cloning, tissue distribution and kinetic characterization
Biochim. Biophys. Acta
1437
157-169
1999
Homo sapiens
brenda
Toyoda, T.; Sugimoto, H.; Yamashita, S.
Sequence, expression in Escherichia coli, and characterizatiom of lysophospholipase II
Biochim. Biophys. Acta
1437
182-193
1999
Mus musculus
brenda
Ackerman, S.J.; Corrette, S.E.; Rosenberg, H.F.; Bennett, J.C.; Mastrianni, D.M.; Nicholson-Weller, A.; Weller, P.F.; Chin, D.T.; Tenen, D.G.
Molecular cloning and characterization of human eosinophil Charcot-Leyden crystal protein (lysophospholipase)
J. Immunol.
150
456-468
1993
Homo sapiens
brenda
Delagebeaudeuf, C.; Gassama-Diagne, A.; Nauze, M.; Ragab, A.; Li, R.Y.; Capdevielle, J.; Ferrara, P.; Fauvel, J.; Chap, H.
Biochemical characterization and cloning of guinea pig intestinal phospholipase B
Ann. N. Y. Acad. Sci.
859
192-193
1998
Cavia porcellus
brenda
Gross, R.W.
Purification of lysophospholipase and lysophospholipase-transacylase from rabbit myocardium
Methods Enzymol.
197
475-482
1991
Oryctolagus cuniculus
brenda
Sugimoto, H.; Yamashita, S.
Purification, characterization, and inhibition by phosphatidic acid of lysophospholipase transacylase from rat liver
J. Biol. Chem.
269
6252-6258
1994
Rattus norvegicus
brenda
Sunaga, H.; Sugimoto, H.; Nagamachi, Y.; Yamashita, S.
Purification and properties of lysophospholipase isoenzymes from pig gastric mucosa
Biochem. J.
308
551-557
1995
Sus scrofa
brenda
Prabhakaran, K.; Harris, E.B.; Randhawa, B.
Properties of lysophospholipase in Mycobacterium leprae
J. Basic Microbiol.
36
341-349
1996
Mycobacterium leprae
brenda
Pind, S.; Kuksis, A.
Further characterization of a novel phospholipase B (phospholipase A2 - lysophospholipase) from intestinal brush-border membranes
Biochem. Cell Biol.
69
346-357
1991
Cavia porcellus, Rattus norvegicus
brenda
Takahashi, M.; Banno, Y.; Shikano, Y.; Mori, S.; Nozawa, Y.
Purification and characterization of lysophospholipase-transacylase of pathogenic fungus Candida albicans
Biochim. Biophys. Acta
1082
161-169
1991
Candida albicans
brenda
Zhang, Y.; Dennis, E.A.
Purification and characterization of a lysophospholipase from a macrophage-like cell line P388D1
J. Biol. Chem.
263
9965-9972
1988
Mus musculus
brenda
Ottolenghi, A.; Rowland, J.T.
Phospholipase and lysophospholipase activity of rat eosinophil leukocytes
Arch. Biochem. Biophys.
406
190-202
2002
Rattus norvegicus
brenda
Tamura, M.; Ajayi, T.; Allmond, L.R.; Moriyama, K.; Wiener-Kronish, J.P.; Sawa, T.
Lysophospholipase A activity of Pseudomonas aeruginosa type III secretory toxin ExoU
Biochem. Biophys. Res. Commun.
316
323-331
2004
Pseudomonas aeruginosa
brenda
Chen, S.C.; Wright, L.C.; Golding, J.C.; Sorrell, T.C.
Purification and characterization of secretory phospholipase B, lysophospholipase and lysophospholipase/transacylase from a virulent strain of the pathogenic fungus Cryptococcus neoformans
Biochem. J.
347
431-439
2000
Cryptococcus neoformans
brenda
Baker, R.R.; Chang, H.y.
A metabolic path for the degradation of lysophosphatidic acid, an inhibitor of lysophosphatidylcholine lysophospholipase, in neuronal nuclei of cerebral cortex
Biochim. Biophys. Acta
1483
58-68
2000
Oryctolagus cuniculus
brenda
Wang, A.; Johnson, C.A.; Jones, Y.; Ellisman, M.H.; Dennis, E.A.
Subcellular localization and PKC-dependent regulation of the human lysophospholipase A/acyl-protein thioesterase in WISH cells
Biochim. Biophys. Acta
1484
207-214
2000
Homo sapiens
brenda
Coe, J.G.S.; Wilson, C.F.; Sorrell, T.C.; Latouche, N.G.; Wright, L.C.
Cloning of CnLYSO1, a novel extracellular lysophospholipase of the pathogenic fungus Cryptococcus neoformans
Gene
316
67-78
2003
Cryptococcus neoformans (Q8NKD2), Cryptococcus neoformans
brenda
Flieger, A.; Neumeister, B.; Cianciotto, N.P.
Characterization of the gene encoding the major secreted lysophospholipase A of Legionella pneumophila and its role in detoxification of lysophosphatidylcholine
Infect. Immun.
70
6094-6106
2002
Legionella pneumophila (Q8GNM7), Legionella pneumophila
brenda
Flieger, A.; Gong, S.; Faigle, M.; Stevanovic, S.; Cianciotto, N.P.; Neumeister, B.
Novel lysophospholipase A secreted by Legionella pneumophila
J. Bacteriol.
183
2121-2124
2001
Legionella pneumophila
brenda
Farn, J.L.; Strugnell, R.A.; Hoyne, P.A.; Michalski, W.P.; Tennent, J.M.
Molecular characterization of a secreted enzyme with phospholipase B activity from Moraxella bovis
J. Bacteriol.
183
6717-6720
2001
Moraxella bovis (Q939K7), Moraxella bovis
brenda
Alasnier, C.; Gandemer, G.
Activities of phospholipases A and lysophospholipases in glycolytic and oxidative skeletal muscles in the rabbit
J. SCI. FOOD AGRIC.
80
698-704
2000
Oryctolagus cuniculus
brenda
Quistad, G.B.; Casida, J.E.
Lysophospholipase inhibition by organophosphorus toxicants
Toxicol. Appl. Pharmacol.
196
319-326
2004
Mus musculus, Vibrio sp.
brenda
Shanado, Y.; Kometani, M.; Uchiyama, H.; Koizumi, S.; Teno, N.
Lysophospholipase I identified as a ghrelin deacylation enzyme in rat stomach
Biochem. Biophys. Res. Commun.
325
1487-1494
2004
Rattus norvegicus
brenda
Taniyama, Y.; Fuse, H.; Satomi, T.; Tozawa, R.; Yasuhara, Y.; Shimakawa, K.; Shibata, S.; Hattori, M.; Nakata, M.; Taketomi, S.
Loss of lysophospholipase 3 increases atherosclerosis in apolipoprotein E-deficient mice
Biochem. Biophys. Res. Commun.
330
104-110
2005
Mus musculus
brenda
Wright, L.C.; Payne, J.; Santangelo, R.T.; Simpanya, M.F.; Chen, S.C.; Widmer, F.; Sorrell, T.C.
Cryptococcal phospholipases: a novel lysophospholipase discovered in the pathogenic fungus Cryptococcus gattii
Biochem. J.
384
377-384
2004
Cryptococcus gattii VGIII, Cryptococcus neoformans
brenda
Lo, Y.C.; Lin, S.C.; Shaw, J.F.; Liaw, Y.C.
Substrate specificities of Escherichia coli thioesterase I/protease I/lysophospholipase L1 are governed by its switch loop movement
Biochemistry
44
1971-1979
2005
Escherichia coli (P0ADA1), Escherichia coli
brenda
Flieger, A.; Rydzewski, K.; Banerji, S.; Broich, M.; Heuner, K.
Cloning and characterization of the gene encoding the major cell-associated phospholipase A of Legionella pneumophila, plaB, exhibiting hemolytic activity
Infect. Immun.
72
2648-2658
2004
Legionella pneumophila
brenda
Broich, M.; Rydzewski, K.; McNealy, T.L.; Marre, R.; Flieger, A.
The global regulatory proteins LetA and RpoS control phospholipase A, lysophospholipase A, acyltransferase, and other hydrolytic activities of Legionella pneumophila JR32
J. Bacteriol.
188
1218-1226
2006
Legionella pneumophila, Legionella pneumophila JR32
brenda
Hirano, K.; Matsui, H.; Tanaka, T.; Matsuura, F.; Satouchi, K.; Koike, T.
Production of 1,2-didocosahexaenoyl phosphatidylcholine by bonito muscle lysophosphatidylcholine/transacylase
J. Biochem.
136
477-483
2004
Katsuwonus pelamis
brenda
Gauster, M.; Rechberger, G.; Sovic, A.; Horl, G.; Steyrer, E.; Sattler, W.; Frank, S.
Endothelial lipase releases saturated and unsaturated fatty acids of high density lipoprotein phosphatidylcholine
J. Lipid Res.
46
1517-1525
2005
Homo sapiens
brenda
Douard, V.; Gassama-Diagne, A.; Hermier, D.; Blesbois, E.
Activity of phospholipases A and lysophospholipase in turkey semen and oviducal fluid
Poult. Sci.
83
1385-1393
2004
Meleagris gallopavo
brenda
Jones, P.M.; Turner, K.M.; Djordjevic, J.T.; Sorrell, T.C.; Wright, L.C.; George, A.M.
Role of conserved active site residues in catalysis by phospholipase B1 from Cryptococcus neoformans
Biochemistry
46
10024-10032
2007
Cryptococcus neoformans
brenda
Koehler, G.A.; Brenot, A.; Haas-Stapleton, E.; Agabian, N.; Deva, R.; Nigam, S.
Phospholipase A2 and phospholipase B activities in fungi
Biochim. Biophys. Acta
1761
1391-1399
2006
Saccharomyces cerevisiae, Candida albicans, Cryptococcus neoformans, Aspergillus fumigatus (B0XZV8), Aspergillus fumigatus (B0Y665), Aspergillus fumigatus (Q9P8P4), Cryptococcus gattii VGIII (Q96WX0)
brenda
Lee, L.; Liaw, Y.; Lee, Y.; Shaw, J.
Enhanced preference for pi-bond containing substrates is correlated to Pro110 in the substrate-binding tunnel of Escherichia coli thioesterase I/protease I/lysophospholipase L1
Biochim. Biophys. Acta
1774
959-967
2007
Escherichia coli (P0ADA1), Escherichia coli
brenda
Fujino, S.; Akiyama, D.; Akaboshi, S.; Fujita, T.; Watanabe, Y.; Tamai, Y.
Purification and characterization of phospholipase B from Candida utilis
Biosci. Biotechnol. Biochem.
70
377-386
2006
Cyberlindnera jadinii (Q7Z8L3), Cyberlindnera jadinii
brenda
Wright, L.C.; Santangelo, R.M.; Ganendren, R.; Payne, J.; Djordjevic, J.T.; Sorrell, T.C.
Cryptococcal lipid metabolism: phospholipase B1 is implicated in transcellular metabolism of macrophage-derived lipids
Eukaryot. Cell
6
37-47
2007
Cryptococcus neoformans
brenda
Fan, J.; Yang, W.; Brindley, P.J.
Lysophospholipase from the human blood fluke, Schistosoma japonicum
Int. J. Infect. Dis.
12
143-151
2007
Schistosoma japonicum, Schistosoma japonicum (Q9U8F2)
brenda
Kwatia, M.A.; Doyle, C.B.; Cho, W.; Enhorning, G.; Ackerman, S.J.
Combined activities of secretory phospholipases and eosinophil lysophospholipases induce pulmonary surfactant dysfunction by phospholipid hydrolysis
J. Allergy Clin. Immunol.
119
838-847
2007
Mus musculus, Homo sapiens (Q05315)
brenda
Ng, C.K.; Obando, D.; Widmer, F.; Wright, L.C.; Sorrell, T.C.; Jolliffe, K.A.
Correlation of antifungal activity with fungal phospholipase inhibition using a series of bisquaternary ammonium salts
J. Med. Chem.
49
811-816
2006
Cryptococcus neoformans
brenda
Ganendren, R.; Carter, E.; Sorrell, T.; Widmer, F.; Wright, L.
Phospholipase B activity enhances adhesion of Cryptococcus neoformans to a human lung epithelial cell line
Microbes Infect.
8
1006-1015
2006
Cryptococcus neoformans (Q9P8P2), Cryptococcus neoformans
brenda
Shiell, B.J.; Tachedjian, M.; Bruce, K.; Beddome, G.; Farn, J.L.; Hoyne, P.A.; Michalski, W.P.
Expression, purification and characterization of recombinant phospholipase B from Moraxella bovis with anomalous electrophoretic behavior
Protein Expr. Purif.
55
262-272
2007
Moraxella bovis (Q939K7), Moraxella bovis
brenda
Read, D.J.; Langford, L.; Barbour, H.R.; Forshaw, P.J.; Glynn, P.
Phospholipase B activity and organophosphorus compound toxicity in cultured neural cells
Toxicol. Appl. Pharmacol.
219
190-195
2007
Mus musculus (Q3TTY0), Mus musculus
brenda
Xu, S.; Zhao, L.; Larsson, A.; Venge, P.
The identification of a phospholipase B precursor in human neutrophils
FEBS J.
276
175-186
2009
Homo sapiens (Q6P4A8), Homo sapiens
brenda
Banerji, S.; Aurass, P.; Flieger, A.
The manifold phospholipases A of Legionella pneumophila - identification, export, regulation, and their link to bacterial virulence
Int. J. Med. Microbiol.
298
169-181
2008
Legionella pneumophila
brenda
Kienesberger, P.C.; Lass, A.; Preiss-Landl, K.; Wolinski, H.; Kohlwein, S.D.; Zimmermann, R.; Zechner, R.
Identification of an Insulin-regulated Lysophospholipase with homology to neuropathy target esterase
J. Biol. Chem.
283
5908-5917
2008
Mus musculus
brenda
Chandrayan, S.K.; Dhaunta, N.; Guptasarma, P.
Expression, purification, refolding and characterization of a putative lysophospholipase from Pyrococcus furiosus: retention of structure and lipase/esterase activity in the presence of water-miscible organic solvents at high temperatures
Protein Expr. Purif.
59
327-333
2008
Pyrococcus furiosus (Q8TZI9)
brenda
Hou, W.Y.; Long, D.X.; Wang, H.P.; Wang, Q.; Wu, Y.J.
The homeostasis of phosphatidylcholine and lysophosphatidylcholine was not disrupted during tri-o-cresyl phosphate-induced delayed neurotoxicity in hens
Toxicology
252
56-63
2008
Gallus gallus (B0FLU6)
brenda
Yamashita, A.; Tanaka, K.; Kamata, R.; Kumazawa, T.; Suzuki, N.; Koga, H.; Waku, K.; Sugiura, T.
Subcellular localization and lysophospholipase/transacylation activities of human group IVC phospholipase A2 (cPLA2gamma)
Biochim. Biophys. Acta
1791
1011-1022
2009
Homo sapiens
brenda
Hsu, K.H.; Wang, S.Y.; Chu, F.H.; Shaw, J.F.
Characterization and heterologous expression of a novel lysophospholipase gene from Antrodia cinnamomea
J. Appl. Microbiol.
108
1712-1722
2009
Taiwanofungus camphoratus (D2T083), Taiwanofungus camphoratus
brenda
Hung, N.D.; Kim, M.R.; Sok, D.E.
Purification and characterization of lysophospholipase C from pig brain
Neurochem. Res.
35
50-59
2010
Sus scrofa
brenda
Hirano, T.; Kishi, M.; Sugimoto, H.; Taguchi, R.; Obinata, H.; Ohshima, N.; Tatei, K.; Izumi, T.
Thioesterase activity and subcellular localization of acylprotein thioesterase 1/lysophospholipase 1
Biochim. Biophys. Acta
1791
797-805
2009
Homo sapiens (Q6IAQ1), Homo sapiens
brenda
Masayama, A.; Kato, S.; Terashima, T.; M?lgaard, A.; Hemmi, H.; Yoshimura, T.; Moriyama, R.
Bacillus subtilis spore coat protein LipC is a phospholipase B
Biosci. Biotechnol. Biochem.
74
24-30
2010
Bacillus subtilis
brenda
Soares, D.A.; de Andrade, R.V.; Silva, S.S.; Bocca, A.L.; Soares Felipe, S.M.; Petrofeza, S.
Extracellular Paracoccidioides brasiliensis phospholipase B involvement in alveolar macrophage interaction
BMC Microbiol.
10
241
2010
Paracoccidioides brasiliensis
brenda
Satou, M.; Nishi, Y.; Yoh, J.; Hattori, Y.; Sugimoto, H.
Identification and characterization of acyl-protein thioesterase 1/lysophospholipase I as a ghrelin deacylation/lysophospholipid hydrolyzing enzyme in fetal bovine serum and conditioned medium
Endocrinology
151
4765-4775
2010
Bos taurus, Homo sapiens, Rattus norvegicus, Mus musculus (Q9WTL7)
brenda
Gao, W.; Li, H.Y.; Xiao, S.; Chye, M.L.
Acyl-CoA-binding protein 2 binds lysophospholipase 2 and lysoPC to promote tolerance to cadmium-induced oxidative stress in transgenic Arabidopsis
Plant J.
62
989-1003
2010
Arabidopsis thaliana
brenda
Cui, Z.; Wang, Y.; Pham, B.P.; Ping, F.; Pan, H.; Cheong, G.W.; Zhang, S.; Jia, B.
High level expression and characterization of a thermostable lysophospholipase from Thermococcus kodakarensis KOD1
Extremophiles
16
619-625
2012
Thermococcus kodakarensis (Q5JIE9)
brenda
Pride, A.C.; Guan, Z.; Trent, M.S.
Characterization of the Vibrio cholerae VolA surface-exposed lipoprotein lysophospholipase
J. Bacteriol.
196
1619-1626
2014
Vibrio cholerae serotype O1
brenda
Karamitros, C.S.; Konrad, M.
Human 60-kDa lysophospholipase contains an N-terminal L-asparaginase domain that is allosterically regulated by L-asparagine
J. Biol. Chem.
289
12962-12975
2014
Homo sapiens
brenda
Zhang, F.; Liang, P.; Chen, W.; Wang, X.; Hu, Y.; Liang, C.; Sun, J.; Huang, Y.; Li, R.; Li, X.; Xu, J.; Yu, X.
Stage-specific expression, immunolocalization of Clonorchis sinensis lysophospholipase and its potential role in hepatic fibrosis
Parasitol. Res.
112
737-749
2013
Clonorchis sinensis
brenda
Kovacic, F.; Granzin, J.; Wilhelm, S.; Kojic-Prodic, B.; Batra-Safferling, R.; Jaeger, K.E.
Structural and functional characterisation of TesA - a novel lysophospholipase A from Pseudomonas aeruginosa
PLoS ONE
8
e69125
2013
Pseudomonas aeruginosa
brenda
Yamaura, S.; Sakasegawa, S.; Koguma, E.; Ueda, S.; Kayamori, Y.; Sugimori, D.; Karasawa, K.
Novel enzymatic method for assaying Lp-PLA2 in serum
Clin. Chim. Acta
481
184-188
2018
Thermocrispum sp. RD004668
brenda
Sharma, A.; Meena, K.; Kanwar, S.
Molecular characterization and bioinformatics studies of a lipase from Bacillus thermoamylovorans BHK67
Int. J. Biol. Macromol.
107
2131-2140
2018
Caldibacillus thermoamylovorans, Caldibacillus thermoamylovorans BHK67
brenda
Liu, N.N.; Liu, Z.S.; Hu, P.; Zhang, Y.; Lu, S.Y.; Li, Y.S.; Yang, Y.J.; Zhang, D.S.; Zhou, Y.; Ren, H.L.
Full-length cDNA cloning, molecular characterization and differential expression analysis of lysophospholipase I from Ovis aries
Int. J. Mol. Sci.
17
E1206
2016
Ovis aries (W8R447), Ovis aries
brenda
Zhu, H.; Liu, P.; Du, J.; Wang, J.; Jing, Y.; Zhang, J.; Gu, W.; Wang, W.; Meng, Q.
Identification of lysophospholipase protein from Spiroplasma eriocheiris and verification of its function
Microbiology
163
175-184
2017
Spiroplasma eriocheiris
brenda
Zhou, L.; Shi, M.; Zhao, L.; Lin, Z.; Tang, Z.; Sun, H.; Chen, T.; Lv, Z.; Xu, J.; Huang, Y.; Yu, X.
Clonorchis sinensis lysophospholipase A upregulates IL-25 expression in macrophages as a potential pathway to liver fibrosis
Parasit. Vectors
10
295
2017
Clonorchis sinensis
brenda
Zhou, L.; Shang, M.; Shi, M.; Zhao, L.; Lin, Z.; Chen, T.; Wu, Y.; Tang, Z.; Sun, H.; Yu, J.; Huang, Y.; Yu, X.
Clonorchis sinensis lysophospholipase inhibits TGF-beta1-induced expression of pro-fibrogenic genes through attenuating the activations of Smad3, JNK2, and ERK1/2 in hepatic stellate cell line LX-2
Parasitol. Res.
115
643-650
2016
Clonorchis sinensis
brenda