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BRENDA support

Ligand glycerophosphocholine

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Basic Ligand Information

Molecular Structure
Picture of glycerophosphocholine (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C8H20NO6P
glycerophosphocholine
SUHOQUVVVLNYQR-MRVPVSSYSA-O
Synonyms:
glycero-3-phosphocholine, glycerolphosphocholine, glycerophospho-choline, Glycerophosphorylcholine, L-alpha-glycerophosphorylcholine, sn-3-glycerophosphocholine, sn-glycero-3-phosphocholine, sn-glycero 3-phosphocholine, sn-glycero 3-phosphorylcholine, sn-glycerol-3-phosphocholine, sn-glycerophosphocholine

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (10 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE

In Vivo Product in Enzyme-catalyzed Reactions (8 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
1-O-alkyl-2-lyso-sn-glycero-3-phosphocholine + tetrahydrobiopterin + O2 = glycerophosphocholine + alkylaldehyde + dihydrobiopterin + H2O
show the reaction diagram
-

Substrate in Enzyme-catalyzed Reactions (29 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
glycerophosphorylcholine + H2O = glycerol + phosphorylcholine
show the reaction diagram
-
glycerophosphocholine + H2O = choline + glycerolphosphate
show the reaction diagram
-

Product in Enzyme-catalyzed Reactions (51 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
1-O-alkyl-2-lyso-sn-glycero-3-phosphocholine + tetrahydrobiopterin + O2 = glycerophosphocholine + alkylaldehyde + dihydrobiopterin + H2O
show the reaction diagram
-
sn-2-acyl-phosphatidylcholine + 1,2-diacylglycerol = triacylglycerol + glycerophosphocholine
show the reaction diagram
-
1-oleoyl-sn-glycero-3-phosphocholine + glycerophosphocholine = glycero-3-phosphocholine + 1-oleoyl-sn-glycero-3-phosphocholine
show the reaction diagram
-
1-oleoyl-2-lyso-phosphatidylcholine + H2O = glycerophosphocholine + oleate
show the reaction diagram
-
1-palmitoyl lysophosphatidylcholine + H2O = glycerophosphocholine + palmitate
show the reaction diagram
-

Activator in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
activates below 0.03 mM
-

Inhibitor in Enzyme-catalyzed Reactions (4 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
above 0.03 mM, competitive
-
competitive inhibition
-

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (5 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
220
-
-

KM Value (23 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.344
-
Vmax 484 nmol/min mg

References & Links

Links to other databases for glycerophosphocholine

ChEBI
PubChem
-
PubChem