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Novel phosphoserine phosphatase inhibitors
1997
Hawkinson, J.E.; Acosta-Burruel, M.; Ta, N.D.; Wood, P.L.
Eur. J. Pharmacol.
337
315-324
Enzymic formation of glycerol 1:2-cyclic phosphate
1976
Clarke, N.; Dawson, R.M.C.
Biochem. J.
153
745-747
Purification and some properties of phospholipase B from Schizosaccharomyces pombe
1996
Oishi, H.; Tsuda, S.; Watanabe, Y.; Tamai, Y.
Biosci. Biotechnol. Biochem.
60
1087-1092
Phospholipase B from the plasma membrane of Saccharomyces cerevisiae
1984
Witt, W.; Schweingruber, M.E.; Mertsching, A.
Biochim. Biophys. Acta
795
108-116
Lysophospholipase-transacylase from rat lung
1981
Van den Bosch, H.; Vianen, G.M.; van Heusden, G.P.H.
Methods Enzymol.
71
513-521
Studies on lysophospholipases. I. Purification and some properties of a lysophospholipase from beef pancreas
1973
Van den Bosch, H.; Aarsman, A.J.; de Jong, J.G.; van Deenen, L.L.M.
Biochim. Biophys. Acta
296
94-104
Purification and characterization of lysophospholipase-transacylase (h-LPTA) from a highly virulant strain of Candida albicans
1995
Mirbod, F.; Banno, Y.; Ghannoum, M.A.; Ibrahim, A.S.; Nakashima, S.; Kitajima, Y.; Cole, G.T.; Nozawa, Y.
Biochim. Biophys. Acta
1257
181-188
Purification and properties of lysophospholipase isoenzymes from pig gastric mucosa
1995
Sunaga, H.; Sugimoto, H.; Nagamachi, Y.; Yamashita, S.
Biochem. J.
308
551-557
Purification and characterization of lysophospholipase-transacylase of pathogenic fungus Candida albicans
1991
Takahashi, M.; Banno, Y.; Shikano, Y.; Mori, S.; Nozawa, Y.
Biochim. Biophys. Acta
1082
161-169
-
Purification and mode of action of phytase from Phaseolus aureus
1974
Maiti, I.B.; Majumder, A.L.; Biswas, B.B.
Phytochemistry
13
1047-1051
Multiple forms of the enzyme glycerophosphodiesterase are present in human brain
1995
Ross, B.M.; Sherwin, A.L.; Kish, S.J.
Lipids
30
1075-1081
Evolutionary comparison of enzyme activities of phosphatidylcholine metabolism in the nervous system of an invertebrate (Loligo pealei), lower vertebrate (Mustelus canis) and the rat
1995
Anfuso, C.D.; Sipione S.; Lupo, G.; Alberghina, M.
Comp. Biochem. Physiol. B
112
493-501
Ca2+ dependent activation of rat uterine glycerylphosphorylcholine diesterase: Presence of a positive modulator protein in uterine secretion
1994
Mitra, Y.; Chowdhury, M.
Mol. Cell. Biochem.
139
101-108
Osmoregulation of GPC:choline phosphodiesterase in MDCK cells: different effects of urea and NaCl
1995
Kwon, E.D.; Zablocki, K.; Jung, K.Y.; Peters, E.M.; Gaarcia-perez, A.; Burg, M.B.
Am. J. Physiol.
269
C35-C41
Purification and properties of a glycerophosphocholine phosphodiesterase from bovine brain myelin
1994
Yuan, J.; Kanfer, J.N.
Neurochem. Res.
19
43-48
Glycerylphosphorylcholine (GPC) diesterase related alterations in the oxygen consumption profile of rat spermatozoa in differing functional states
1992
Mitra, J.; Chowdhury, M.
Int. J. Androl.
15
345-354
Purification and characterization of rat uterine glycerylphosphorylcholine diesterase and its tissue-specific induction by 17-beta-estradiol
1991
Mitra, J.; Chowdhury, M
Endocrinology
129
1147-1154
Accumulation of glycerophosphocholine (GPC) by renal cells: Osmotic regulation of GPC:choline phosphodiesterase
1991
Zablocki, K.; Miller, S.P.F.; Garcia-Perez, A.; Burg, M.B.
Proc. Natl. Acad. Sci. USA
88
7820-7824
GPC phosphodiesterase and phosphomonoesterase activities of renal cortex and medulla of control, antdiuresis and diuresis rats
1989
Kanfer, J.N.; McCartney, D.G.
FEBS Lett.
257
348-350
Purification and characterization of glpQ-encoded glycerophosphodiester phosphodiesterase from Escherichia coli K-12
1988
Larson, T.J.; van Loo-Bhattacharya, A.T.
Arch. Biochem. Biophys.
260
577-584
Utilization of exogenous glycerophosphodiesters and glycerol 3-phosphate by inositol-starved yeast, Saccharomyces uvarum
1985
Paltauf, F.; Zinser, E.; Daum, G.
Biochim. Biophys. Acta
835
322-330
Activation of glycerophosphocholine phosphodiesterase in rat forebrain by Ca2+
1982
Spanner, S.; Ansell, G.B.
Biochem. J.
208
845-850
Lipid catabolism of cultivated treponemes
1982
Trevathan, C.A.; Smibert, R.M.; George, H.A.
Can. J. Microbiol.
28
672-678
Some characteristics of sn-glycero 3-phosphocholine diesterases from rat brain
1976
Abra, R.M.; Quinn, P.J.
Biochim. Biophys. Acta
431
631-639
A novel pathway for phosphatidylcholine catabolism in rat brain homogenates
1975
Abra, R.M.; Quinn, P.J.
Biochim. Biophys. Acta
380
436-441
-
Glycerylphosphorylcholine phosphodiesterase in rat liver plasma membranes
1972
Lloyd-Davies, K.A.; Michell, R.H.; Coleman, R.
Biochem. J.
127
36
Glycerylphosphorylcholine phosphodiesterase in rat liver
1972
Lloyd-Davies, K.A.; Michell, R.H.; Coleman, R.
Biochem. J.
127
357-368
Glycerylphosphorylcholine diesterase: Effects of metal-binding agents
1969
Baldwin, J.J.; Lanes, P.; Cornatzer, W.E.
Arch. Biochem. Biophys.
133
224-232
Glycerylphosphorylcholine diesterase: Effects of dietary choline deficiency
1969
Baldwin, J.J.; Cornatzer, W.E.
Biochim. Biophys. Acta
176
193-195
Rat kidney glycerylphosphorylcholine diesterase
1968
Baldwin, J.J.; Cornatzer, W.E.
Biochim. Biophys. Acta
164
195-204
Metabolism of phospholipides by bacterial enzymes
1954
Hayaishi, O.; Kornberg, A.
J. Biol. Chem.
206
647-663
Glycerylphosphocholine phosphocholine phosphodiesterase activity is reduced in multiple sclerosis plaques
1990
Janzen, L.; Tourtellotte, W.W.; Kanfer J.N.
Exp. Neurol.
109
243-246
Characterization of a Zn(2+)-requiring glycerophosphocholine cholinephosphodiesterase possessing p-nitrophenylphosphocholine phosphodiesterase activity
1992
Sok D.E.; Kim, M.R.
Biochem. J.
286
435-440
Glycerophosphorylcholine phosphocholine phosphodiesterase activity of rat brain myelin
1989
Kanfer, J.N; McCartney, D.G.
J. Neurosci. Res.
24
231-240
Continuous spectrophotometric assay of phospholipase A2 activity hydrolyzing plasmalogens using coupling enzymes
1989
Hirashima, Y.; Jurkowitz-Alexander, M.S.; Farooqui, A.A.; Horrocks, L.A.
Anal. Biochem.
176
180-184
The catabolism of plasmenylcholine in the guinea pig heart
1986
Arthur, G.; Page, L.; Mock, T.; Choy, P.C.
Biochem. J.
236
475-480
The metabolism of plasmalogen: enzymatic hydrolysis of the vinyl ether
1961
Warner, H.R.; Lands, W.E.M.
J. Biol. Chem.
236
2404-2409
dentification and characterization of alkenyl hydrolase (lysoplasmalogenase) in microsomes and identification of a plasmalogen-active phospholipase A2 in cytosol of small intestinal epithelium
1999
Jurkowitz, M.S.; Horrocks, L.A.; Litsky, M.L.
Biochim. Biophys. Acta
1437
142-156
Solubilization, purification and characterization of lysoplasmalogen alkenylhydrolase (lysoplasmalogenase) from rat liver microsomes
1989
Jurkowitz-Alexander, M.; Ebata, H.; Mills, J.S.; Murphy, E.J.; Horrocks, L.A.
Biochim. Biophys. Acta
1002
203-212
Fluorimetric coupled enzyme assay for lysoplasmalogenase activity in liver
1989
Hirashima, Y.; Farooqui, A.A.; Horrocks, L.A.
Biochem. J.
260
605-608
-
Assay procedures and properties of plasmalogenase, lysoplasmalogenase and plasmalogen specific phospholipase A2
1989
Hirashima, Y.; Farooqui, A.A.; Horrocks, L.A.
Front. Chem.
1
91-102
Evidence for an oleoyl phosphatidylcholine desaturase in microsomal preparations from cotyledons of safflower (Carthamus tinctorius) seed
1979
Slack, C.R.; Grattan Roughan, P.; Browse, J.
Biochem. J.
179
649-656
The involvement of phospholipid:diacylglycerol acyltransferases in triacylglycerol production
2000
Banas, A.; Dahlqvist, A.; Stahl, U.; Lenman, M.; Stymne, S.
Biochem. Soc. Trans.
28
703-705
Phospholipid:diacylglycerol acyltransferase: an enzyme that catalyzes the acyl-CoA-independent formation of triacylglycerol in yeast and plants
2000
Dahlqvist, A.; Stahl, U.; Lenman, M.; Banas, A.; Lee, M.; Sandager, L.; Ronne, H.; Stymne, S.
Proc. Natl. Acad. Sci. USA
97
6487-6492
Periplasmic glycerophosphodiester phosphodiesterase of Escherichia coli, a new enzyme of the glp regulon
1983
Larson, T.J.; Ehrmann, M.; Boos, W.
J. Biol. Chem.
258
5428-5432
Glycerol-3-phosphate acquisition in spirochetes: distribution and biological activity of glycerophosphodiester phosphodiesterase (GlpQ) among Borrelia species
2003
Schwan, T.G.; Battisti, J.M.; Porcella, S.F.; Raffel, S.J.; Schrumpf, M.E.; Fischer, E.R.; Carroll, J.A.; Stewart, P.E.; Rosa, P.; Somerville, G.A.
J. Bacteriol.
185
1346-1356
Identification and characterisation of plant glycerophosphodiester phosphodiesterase
2004
Van Der Rest, B.; Rolland, N.; Boisson, A.M.; Ferro, M.; Bligny, R.; Douce, R.
Biochem. J.
379
601-607
Glycerophosphocholine metabolism in higher plant cells. Evidence of a new glyceryl-phosphodiester phosphodiesterase
2002
Van der Rest, B.; Boisson, A.M.; Gout, E.; Bligny, R.; Douce, R.
Plant Physiol.
130
244-255
Phospholipase and lysophospholipase activity of rat eosinophil leukocytes
2002
Ottolenghi, A.; Rowland, J.T.
Arch. Biochem. Biophys.
406
190-202
Lysophospholipase A activity of Pseudomonas aeruginosa type III secretory toxin ExoU
2004
Tamura, M.; Ajayi, T.; Allmond, L.R.; Moriyama, K.; Wiener-Kronish, J.P.; Sawa, T.
Biochem. Biophys. Res. Commun.
316
323-331
Purification and characterization of secretory phospholipase B, lysophospholipase and lysophospholipase/transacylase from a virulent strain of the pathogenic fungus Cryptococcus neoformans
2000
Chen, S.C.; Wright, L.C.; Golding, J.C.; Sorrell, T.C.
Biochem. J.
347
431-439
A metabolic path for the degradation of lysophosphatidic acid, an inhibitor of lysophosphatidylcholine lysophospholipase, in neuronal nuclei of cerebral cortex
2000
Baker, R.R.; Chang, H.y.
Biochim. Biophys. Acta
1483
58-68
Subcellular localization and PKC-dependent regulation of the human lysophospholipase A/acyl-protein thioesterase in WISH cells
2000
Wang, A.; Johnson, C.A.; Jones, Y.; Ellisman, M.H.; Dennis, E.A.
Biochim. Biophys. Acta
1484
207-214
Cloning of CnLYSO1, a novel extracellular lysophospholipase of the pathogenic fungus Cryptococcus neoformans
2003
Coe, J.G.S.; Wilson, C.F.; Sorrell, T.C.; Latouche, N.G.; Wright, L.C.
Gene
316
67-78
Characterization of the gene encoding the major secreted lysophospholipase A of Legionella pneumophila and its role in detoxification of lysophosphatidylcholine
2002
Flieger, A.; Neumeister, B.; Cianciotto, N.P.
Infect. Immun.
70
6094-6106
Novel lysophospholipase A secreted by Legionella pneumophila
2001
Flieger, A.; Gong, S.; Faigle, M.; Stevanovic, S.; Cianciotto, N.P.; Neumeister, B.
J. Bacteriol.
183
2121-2124
Molecular characterization of a secreted enzyme with phospholipase B activity from Moraxella bovis
2001
Farn, J.L.; Strugnell, R.A.; Hoyne, P.A.; Michalski, W.P.; Tennent, J.M.
J. Bacteriol.
183
6717-6720
Activities of phospholipases A and lysophospholipases in glycolytic and oxidative skeletal muscles in the rabbit
2000
Alasnier, C.; Gandemer, G.
J. SCI. FOOD AGRIC.
80
698-704
Characterization of glycerophosphocholine phosphodiesterase activity and phosphatidylcholine biosynthesis in cultured retinal microcapillary pericytes. Effect of adenosine and endothelin-1
2003
Anfuso, C.D.; Sipione, S.; Lupo, G.; Ragusa, N.; Alberghina, M.
Lipids
38
45-52
GDE1/MIR16 is a glycerophosphoinositol phosphodiesterase regulated by stimulation of G protein-coupled receptors
2003
Zheng, B.; Berrie, C.P.; Corda, D.; Farquhar, M.G.
Proc. Natl. Acad. Sci. USA
100
1745-1750
Lysophospholipase inhibition by organophosphorus toxicants
2004
Quistad, G.B.; Casida, J.E.
Toxicol. Appl. Pharmacol.
196
319-326
-
Selective inhibition of Zn2+-glycerophosphocholine cholinephosphodiesterase by tellurium tetrachloride
1992
Sok, D.E.; Kim, M.R.
Biochem. J.
284
641-643
Biochemical and molecular characterization of a novel choline-specific glycerophosphodiester phosphodiesterase belonging to the nucleotide pyrophosphatase/phosphodiesterase family
2005
Sakagami, H.; Aoki, J.; Natori, Y.; Nishikawa, K.; Kakehi, Y.; Arai, H.
J. Biol. Chem.
280
23084-23093
Glycerophosphocholine catabolism as a new route for choline formation for phosphatidylcholine synthesis by the Kennedy pathway
2005
Fernandez-Murray, J.P.; McMaster, C.R.
J. Biol. Chem.
280
38290-38296
The purification, crystallization and preliminary diffraction of a glycerophosphodiesterase from Enterobacter aerogenes
2006
Jackson, C.J.; Carr, P.D.; Kim, H.K.; Liu, J.W.; Ollis, D.L.
Acta Crystallogr. Sect. F
62
659-661
Transport and metabolism of glycerophosphodiesters produced through phospholipid deacylation
2007
Patton-Vogt, J.
Biochim. Biophys. Acta
1771
337-342
Mammalian glycerophosphodiester phosphodiesterases
2007
Yanaka, N.
Biosci. Biotechnol. Biochem.
71
1811-1818
Escherichia coli cytosolic glycerophosphodiester phosphodiesterase (UgpQ) requires Mg2+, Co2+, or Mn2+ for its enzyme activity
2008
Ohshima, N.; Yamashita, S.; Takahashi, N.; Kuroishi, C.; Shiro, Y.; Takio, K.
J. Bacteriol.
190
1219-1223
Pneumococcal Haemophilus influenzae protein D conjugate vaccine induces antibodies that inhibit glycerophosphodiester phosphodiesterase activity of protein D
2008
Toropainen, M.; Raitolehto, A.; Henckaerts, I.; Wauters, D.; Poolman, J.; Lestrate, P.; Kaeyhty, H.
Infect. Immun.
76
4546-4553
Crystal structure of glycerophosphodiester phosphodiesterase (GDPD) from Thermoanaerobacter tengcongensis, a metal ion-dependent enzyme: insight into the catalytic mechanism
2008
Shi, L.; Liu, J.F.; An, X.M.; Liang, D.C.
Proteins
72
280-288
Protein D of Haemophilus influenzae: a protective nontypeable H. influenzae antigen and a carrier for pneumococcal conjugate vaccines
2008
Forsgren, A.; Riesbeck, K.; Janson, H.
Clin. Infect. Dis.
46
726-731
A novel glycerophosphodiester phosphodiesterase, GDE5, controls skeletal muscle development via a non-enzymatic mechanism
2010
Okazaki, Y.; Ohshima, N.; Yoshizawa, I.; Kamei, Y.; Mariggio, S.; Okamoto, K.; Maeda, M.; Nogusa, Y.; Fujioka, Y.; Izumi, T.; Ogawa, Y.; Shiro, Y.; Wada, M.; Kato, N.; Corda, D.; Yanaka, N.
J. Biol. Chem.
285
27652-27663
White lupin cluster root acclimation to phosphorus deficiency and root hair development involve unique glycerophosphodiester phosphodiesterases
2011
Cheng, L.; Bucciarelli, B.; Liu, J.; Zinn, K.; Miller, S.; Patton-Vogt, J.; Allan, D.; Shen, J.; Vance, C.P.
Plant Physiol.
156
1131-1148
A trigger enzyme in Mycoplasma pneumoniae: impact of the glycerophosphodiesterase GlpQ on virulence and gene expression
2011
Schmidl, S.R.; Otto, A.; Lluch-Senar, M.; Pinol, J.; Busse, J.; Becher, D.; Stuelke, J.
PLoS Pathog.
7
e1002263
The emerging physiological roles of the glycerophosphodiesterase family
2014
Corda, D.; Mosca, M.; Ohshima, N.; Grauso, L.; Yanaka, N.; Mariggio, S.
FEBS J.
281
998-1016
Purification, characterization, molecular cloning, and extracellular production of a novel bacterial glycerophosphocholine cholinephosphodiesterase from Streptomyces sanglieri
2014
Sugimori, D.; Ogasawara, J.; Okuda, K.; Murayama, K.
J. Biosci. Bioeng.
117
422-430
Bovine brain myelin glycerophosphocholine choline phosphodiesterase is an alkaline lysosphingomyelinase of the eNPP-family, regulated by lysosomal sorting
2013
Greiner-Tollersrud, L.; Berg, T.; Stensland, H.M.; Evjen, G.; Greiner-Tollersrud, O.K.
Neurochem. Res.
38
300-310
Glycerophosphodiester phosphodiesterase domain containing 5 (GDPD5) expression correlates with malignant choline phospholipid metabolite profiles in human breast cancer
2012
Cao, M.D.; Doepkens, M.; Krishnamachary, B.; Vesuna, F.; Gadiya, M.M.; Loenning, P.E.; Bhujwalla, Z.M.; Gribbestad, I.S.; Glunde, K.
NMR Biomed.
25
1033-1042
Novel reactions in acyl editing of phosphatidylcholine by lysophosphatidylcholine transacylase (LPCT) and acyl-CoA:glycerophosphocholine acyltransferase (GPCAT) activities in microsomal preparations of plant tissues
2015
Lager, I.; Glab, B.; Eriksson, L.; Chen, G.; Banas, A.; Stymne, S.
Planta
241
347-358
GDPD5, a choline-generating enzyme and its novel role in tumor cell migration
2016
Marchan, R.
Arch. Toxicol.
90
3143-3144
Expression and characterization of a novel glycerophosphodiester phosphodiesterase from Pyrococcus furiosus DSM 3638 that possesses lysophospholipase D activity
2016
Wang, F.; Lai, L.; Liu, Y.; Yang, B.; Wang, Y.
Int. J. Mol. Sci.
17
831
The baseplate of Lactobacillus delbrueckii bacteriophage Ld17 harbors a glycerophosphodiesterase
2016
Cornelissen, A.; Sadovskaya, I.; Vinogradov, E.; Blangy, S.; Spinelli, S.; Casey, E.; Mahony, J.; Noben, J.P.; Dal Bello, F.; Cambillau, C.; van Sinderen, D.
J. Biol. Chem.
291
16816-16827
A novel glycerophosphodiester phosphodiesterase improves phosphate deficiency tolerance in rice
2018
Mehra, P.; Pandey, B.K.; Verma, L.; Giri, J.
Plant Cell Environ.
42
1167-1179
Rice and chickpea GDPDs are preferentially influenced by low phosphate and CaGDPD1 encodes an active glycerophosphodiester phosphodiesterase enzyme
2016
Mehra, P.; Giri, J.
Plant Cell Rep.
35
1699-1717
Structure and biological function of ENPP6, a choline-specific glycerophosphodiester-phosphodiesterase
2016
Morita, J.; Kano, K.; Kato, K.; Takita, H.; Sakagami, H.; Yamamoto, Y.; Mihara, E.; Ueda, H.; Sato, T.; Tokuyama, H.; Arai, H.; Asou, H.; Takagi, J.; Ishitani, R.; Nishimasu, H.; Nureki, O.; Aoki, J.
Sci. Rep.
6
20995
Cloning of glycerophosphocholine acyltransferase (GPCAT) from fungi and plants a novel enzyme phosphatidylcholine synthesis
2016
Glab, B.; Beganovic, M.; Anaokar, S.; Hao, M.S.; Rasmusson, A.G.; Patton-Vogt, J.; Banas, A.; Stymne, S.; Lager, I.
J. Biol. Chem.
291
25066-25076
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