Cloned (Comment) | Organism |
---|---|
expressed in Escherichia coli BL21(DE3) cells | Clonorchis sinensis |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
2-lysophosphatidylcholine + H2O | Clonorchis sinensis | - |
glycerophosphocholine + a carboxylate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Clonorchis sinensis | - |
- |
- |
Purification (Comment) | Organism |
---|---|
His Bind Purification Kit | Clonorchis sinensis |
Source Tissue | Comment | Organism | Textmining |
---|
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
2-lysophosphatidylcholine + H2O | - |
Clonorchis sinensis | glycerophosphocholine + a carboxylate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
lysophospholipase A | - |
Clonorchis sinensis |
lysoPLA | - |
Clonorchis sinensis |
General Information | Comment | Organism |
---|---|---|
physiological function | treating RAW264.7 cells with the enzyme significantly induces interleukin-25 expression. The enzyme activates hepatic stellate cells by upregulating interleukin-25 in macrophages through the protein kinase A-dependent B-Raf/ERK1/2 pathway and potentially promotes hepatic fibrosis during Clonorchis sinensis infection | Clonorchis sinensis |