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Literature summary for 3.1.1.5 extracted from
- The manifold phospholipases A of Legionella pneumophila - identification, export, regulation, and their link to bacterial virulence (2008), Int. J. Med. Microbiol., 298, 169-181.
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | the cytotoxic potential and signalling properties enable Legionella pneumophila PLA, LPLA enzymes to act as bacterial virulence factors, involved in severe lung disease | Legionella pneumophila |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| cell associated | - |
Legionella pneumophila | - |
- |
| extracellular | - |
Legionella pneumophila | - |
- |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| lysophosphatidylcholine + H2O | Legionella pneumophila | lysophospholipase A activity | glycerophosphorylcholine + a carboxylate | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Legionella pneumophila | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| lysophosphatidylcholine + H2O | lysophospholipase A activity | Legionella pneumophila | glycerophosphorylcholine + a carboxylate | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| LPLA | - |
Legionella pneumophila |
| lysophospholipase A | - |
Legionella pneumophila |
| phospholipase A | - |
Legionella pneumophila |
| Pla | - |
Legionella pneumophila |
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Release 2023.1 (January 2023)
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