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1,2-hexadecandiol + palmitoyl-CoA
?
1,8-octanedithiol + palmitoyl-CoA
1-S-monopalmitoyloctanedithiol + CoA
59.3% the rate of hexadecanol, plus minor amounts of 1,8-dipalmitoyloctanedithiol
-
-
?
1-decanol + palmitoyl-CoA
decyl palmitate + CoA
48% the rate of hexacedanol
-
-
?
1-hexadecanethiol + palmitoyl-CoA
palmitic acid hexadecane thio ester
10.4% the rate of hexanol
-
-
?
1-hexadecanethiol + palmitoyl-CoA
palmitic acid hexadecyl thio ester + CoA
1-hexadecanol + palmitoyl-CoA
CoA + hexadecylpalmitate
1-hexadecanol + palmitoyl-CoA
palmitic acid hexadecyl ester + CoA
1-hexanol + palmitoyl-CoA
hexyl palmitate + CoA
-
-
-
?
1-S-monopalmitoyloctanedithiol + palmitoyl-CoA
1,8-dipalmitoyloctanedithiol + CoA
13.4% the rate of hexanol
-
-
?
1-S-monopalmitoyloctanedithiol + palmitoyl-CoA
1,8-S-dipalmitoyloctanedithiol + CoA
2 1,8-octanedithiol + 3 palmitoyl-CoA
1-S-monopalmitoyloctanedithiol + 1,8-S-dipalmitoyloctanedithiol + 3 CoA
2-cyclohexylethanol + palmitoyl-CoA
2-cyclohexylethyl palmitate + CoA
44.8% the rate of hexacedanol
-
-
?
2-decanol + palmitoyl-CoA
dec-2-yl palmitate + CoA
38.8% the rate of hexacedanol
-
-
?
2-phenylethanol + palmitoyl-CoA
2-phenylethyl palmitate + CoA
4-decanol + palmitoyl-CoA
4-decyl palmitate + CoA
15.6% the rate of hexacedanol
-
-
?
acyl-CoA + a long-chain alcohol
CoA + a long-chain ester
acyl-CoA + decanol
CoA + decanyl acylester
-
-
-
?
acyl-CoA + dodecanol
CoA + dodecanyl acylester
-
-
-
?
acyl-CoA + hexadecanol
CoA + hexadecanyl acylester
-
-
-
?
acyl-CoA + long-chain diacylglycerol
CoA + long-chain triacylglycerol
acyl-CoA + long-chain fatty alcohol
CoA + long-chain fatty ester
acyl-CoA + octadecanol
CoA + octadecanyl acylester
-
-
-
?
arachidonoyl-CoA + hexadecan-1-ol
CoA + hexadecyl arachidonoate
-
-
-
?
arachidonoyl-CoA + hexadecanol
CoA + hexadecyl arachidonoate
-
-
-
?
arachidoyl-CoA + decanol
decyl arachidonate + CoA
-
-
-
?
arachidoyl-CoA + docosanol
docosyl arachidonate + CoA
-
-
-
?
arachidoyl-CoA + docosenol
docosenyl arachidonate + CoA
-
-
-
?
arachidoyl-CoA + dodecanol
dodecyl arachidonate + CoA
-
-
-
?
arachidoyl-CoA + eicosanol
eicosanyl arachidonate + CoA
-
-
-
?
arachidoyl-CoA + eicosenol
eicosenyl arachidonate + CoA
-
-
-
?
arachidoyl-CoA + hexadecanol
hexadecyl arachidonate + CoA
-
-
-
?
arachidoyl-CoA + hexadecenol
hexadecenyl arachidonate + CoA
-
-
-
?
arachidoyl-CoA + linolenyl alcohol
linolenyl arachidonate + CoA
-
-
-
?
arachidoyl-CoA + linoleyl alcohol
linoleyl arachidonate + CoA
-
-
-
?
arachidoyl-CoA + octadecanol
octadecyl arachidonate + CoA
-
-
-
?
arachidoyl-CoA + octadecenol
octadecenyl arachidonate + CoA
-
-
-
?
arachidoyl-CoA + phytol
phytyl arachidonate + CoA
-
-
-
?
arachidoyl-CoA + ricinoleyl alcohol
ricinoleyl arachidonate + CoA
-
-
-
?
arachidoyl-CoA + tetracosanol
tetracosyl arachidonate + CoA
-
-
-
?
arachidoyl-CoA + tetracosenol
tetracosenyl arachidonate + CoA
-
-
-
?
arachidoyl-CoA + tetradecanol
tetradecyl arachidonate + CoA
-
-
-
?
cetyl alcohol + oleoyl-CoA
CoA + cetyloleate
-
-
-
?
cis-11-eicosenol + acetyl-CoA
cis-11-eicosenyl acetate + CoA
-
-
-
-
?
cyclododecanol + palmitoyl-CoA
cyclododecyl palmitate + CoA
79.7% the rate of hexacedanol
-
-
?
cyclohexandiol + palmitoyl-CoA
? + CoA
4.1% the rate of hexacedanol
-
-
?
cyclohexanol + palmitoyl-CoA
cyclohexyl palmitate + CoA
32% the rate of hexacedanol
-
-
?
cyclohexanone oxime + palmitoyl-CoA
? + CoA
5.2% the rate of hexacedanol
-
-
?
decanol + palmitoyl-CoA
decanyl palmitate + CoA
-
and undecanol, best substrates
-
-
?
decanoyl-CoA + decanol
decyl decanoate + CoA
low activity
-
-
?
decanoyl-CoA + docosanol
docosyl decanoate + CoA
low activity
-
-
?
decanoyl-CoA + docosenol
docosenyl decanoate + CoA
low activity
-
-
?
decanoyl-CoA + dodecanol
dodecyl decanoate + CoA
low activity
-
-
?
decanoyl-CoA + eicosanol
eicosanyl decanoate + CoA
low activity
-
-
?
decanoyl-CoA + eicosenol
eicosenyl decanoate + CoA
low activity
-
-
?
decanoyl-CoA + hexadecan-1-ol
?
-
-
-
?
decanoyl-CoA + hexadecanol
CoA + hexadecyl decanoate
-
-
-
?
decanoyl-CoA + hexadecanol
hexadecyl decanoate + CoA
low activity
-
-
?
decanoyl-CoA + hexadecenol
hexadecenyl decanoate + CoA
low activity
-
-
?
decanoyl-CoA + linolenyl alcohol
linolenyl decanoate + CoA
low activity
-
-
?
decanoyl-CoA + linoleyl alcohol
linoleyl decanoate + CoA
low activity
-
-
?
decanoyl-CoA + octadecanol
octadecyl decanoate + CoA
low activity
-
-
?
decanoyl-CoA + octadecenol
octadecenyl decanoate + CoA
low activity
-
-
?
decanoyl-CoA + phytol
phytyl decanoate + CoA
very low activity
-
-
?
decanoyl-CoA + ricinoleyl alcohol
ricinoleyl decanoate + CoA
low activity
-
-
?
decanoyl-CoA + tetracosanol
tetracosyl decanoate + CoA
low activity
-
-
?
decanoyl-CoA + tetracosenol
tetracosenyl decanoate + CoA
low activity
-
-
?
decanoyl-CoA + tetradecanol
tetradecyl decanoate + CoA
low activity
-
-
?
dodecan-1-ol + palmitoyl-CoA
CoA + dodecanyl palmitate
dodecanol + palmitoyl-CoA
dodecanyl palmitate + CoA
eicosanoyl-CoA + cis-11-eicosenol
cis-11-eicosenyl eicosanoate + CoA
-
cis-11-eicosenol is the best acceptor
-
-
?
eicosanoyl-CoA + cis-13-eicosenol
cis-13-eicosenyl eicosanoate + CoA
-
-
-
-
?
eicosanoyl-CoA + cis-9-octadecenol
cis-9-octadecenyl eicosanoate + CoA
-
-
-
-
?
eicosanoyl-CoA + decanol
decanyl eicosanoate + CoA
-
low activity
-
-
?
eicosanoyl-CoA + docosanol
docosanyl eicosanoate + CoA
-
low activity
-
-
?
eicosanoyl-CoA + dodecanol
dodecanyl eicosanoate + CoA
-
-
-
-
?
eicosanoyl-CoA + eicosanol
eicosanyl eicosanoate + CoA
-
low activity
-
-
?
eicosanoyl-CoA + hexadecanol
hexadecanyl eicosanoate + CoA
-
-
-
-
?
eicosanoyl-CoA + octadecanol
octadecanyl eicosanoate + CoA
-
low activity
-
-
?
eicosanoyl-CoA + tetradecanol
tetradecanyl eicosanoate + CoA
-
-
-
-
?
eicosapentaenoyl-CoA + hexadecan-1-ol
?
-
-
-
?
eicosapentaenoyl-CoA + hexadecanol
CoA + hexadecyl eicosapentaenoate
-
-
-
?
eicosenoyl-CoA + decanol
decyl eicosenoate + CoA
-
-
-
?
eicosenoyl-CoA + docosanol
docosyl eicosenoate + CoA
-
-
-
?
eicosenoyl-CoA + docosenol
docosenyl eicosenoate + CoA
eicosenoyl-CoA + dodecanol
dodecyl eicosenoate + CoA
eicosenoyl-CoA + eicosanol
eicosanyl eicosenoate + CoA
-
-
-
?
eicosenoyl-CoA + eicosenol
eicosenyl eicosenoate + CoA
-
-
-
?
eicosenoyl-CoA + hexadecanol
hexadecanyl eicosenate + CoA
-
high activity
-
-
?
eicosenoyl-CoA + hexadecanol
hexadecyl eicosenoate + CoA
-
-
-
?
eicosenoyl-CoA + hexadecenol
hexadecenyl eicosenoate + CoA
-
-
-
?
eicosenoyl-CoA + linolenyl alcohol
linolenyl eicosenoate + CoA
-
-
-
?
eicosenoyl-CoA + linoleyl alcohol
linoleyl eicosenoate + CoA
-
-
-
?
eicosenoyl-CoA + octadecanol
octadecyl eicosenoate + CoA
-
-
-
?
eicosenoyl-CoA + octadecenol
octadecenyl eicosenoate + CoA
eicosenoyl-CoA + phytol
phytyl eicosenoate + CoA
-
-
-
?
eicosenoyl-CoA + ricinoleyl alcohol
ricinoleyl eicosenoate + CoA
-
-
-
?
eicosenoyl-CoA + tetracosanol
tetracosyl eicosenoate + CoA
-
-
-
?
eicosenoyl-CoA + tetracosenol
tetracosenyl eicosenoate + CoA
-
-
-
?
eicosenoyl-CoA + tetradecanol
tetradecyl eicosenate + CoA
-
high activity
-
-
?
eicosenoyl-CoA + tetradecanol
tetradecyl eicosenoate + CoA
-
-
-
?
erucyl-CoA + decanol
decyl erucoate + CoA
-
-
-
?
erucyl-CoA + docosanol
docosyl erucoate + CoA
-
-
-
?
erucyl-CoA + docosenol
docosenyl erucoate + CoA
-
-
-
?
erucyl-CoA + dodecanol
dodecyl erucoate + CoA
-
-
-
?
erucyl-CoA + eicosanol
eicosanyl erucoate + CoA
-
-
-
?
erucyl-CoA + eicosenol
eicosenyl erucoate + CoA
-
-
-
?
erucyl-CoA + hexadecanol
hexadecyl erucoate + CoA
-
-
-
?
erucyl-CoA + hexadecenol
hexadecenyl erucoate + CoA
-
-
-
?
erucyl-CoA + linolenyl alcohol
linolenyl erucoate + CoA
-
-
-
?
erucyl-CoA + linoleyl alcohol
linoleyl erucoate + CoA
-
-
-
?
erucyl-CoA + octadecanol
octadecyl erucoate + CoA
-
-
-
?
erucyl-CoA + octadecenol
octadecenyl erucoate + CoA
-
-
-
?
erucyl-CoA + phytol
phytyl erucoate + CoA
-
-
-
?
erucyl-CoA + ricinoleyl alcohol
ricinoleyl erucoate + CoA
-
-
-
?
erucyl-CoA + tetracosanol
tetracosyl erucoate + CoA
-
-
-
?
erucyl-CoA + tetradecanol
tetradecyl erucoate + CoA
-
-
-
?
ethanol + palmitoyl-CoA
ethyl palmitate + CoA
hexadecan-1-ol + palmitoyl-CoA
CoA + hexadecyl palmitate
hexadecanol + palmitoyl-CoA
hexadecanyl palmitate + CoA
hexadecanol + palmitoyl-CoA
hexadecyl palmitate + CoA
-
-
-
?
hexan-1-ol + palmitoyl-CoA
hexyl palmitate + CoA
isoamyl alcohol + palmitoyl-CoA
isoamyl palmitate + CoA
lauroyl-CoA + decanol
decyl laurate + CoA
-
-
-
?
lauroyl-CoA + docosanol
docosyl laurate + CoA
-
-
-
?
lauroyl-CoA + docosenol
docosenyl laurate + CoA
-
-
-
?
lauroyl-CoA + dodecanol
dodecyl laurate + CoA
-
-
-
?
lauroyl-CoA + eicosanol
eicosanyl laurate + CoA
-
-
-
?
lauroyl-CoA + eicosenol
eicosenyl laurate + CoA
-
-
-
?
lauroyl-CoA + hexadecan-1-ol
?
-
-
-
?
lauroyl-CoA + hexadecanol
CoA + hexadecyl laurate
lauroyl-CoA + hexadecanol
hexadecyl laurate + CoA
-
-
-
?
lauroyl-CoA + hexadecenol
hexadecenyl laurate + CoA
-
-
-
?
lauroyl-CoA + linolenyl alcohol
linolenyl laurate + CoA
-
-
-
?
lauroyl-CoA + linoleyl alcohol
linoleyl laurate + CoA
-
-
-
?
lauroyl-CoA + octadecanol
octadecyl laurate + CoA
-
-
-
?
lauroyl-CoA + octadecenol
octadecenyl laurate + CoA
-
-
-
?
lauroyl-CoA + phytol
phytyl laurate + CoA
-
-
-
?
lauroyl-CoA + ricinoleyl alcohol
ricinoleyl laurate + CoA
high activity
-
-
?
lauroyl-CoA + tetracosanol
tetracosyl laurate + CoA
-
-
-
?
lauroyl-CoA + tetracosenol
tetracosenyl laurate + CoA
-
-
-
?
lauroyl-CoA + tetradecanol
tetradecyl laurate + CoA
lauryl-CoA + 1,2-dipalmitoyl-sn-glycerol
?
-
-
-
-
?
lauryl-CoA + tetradecanol
tetradecanyl laurate + CoA
-
-
-
?
lauryol-CoA + hexadecanol
hexadecanyl laurate + CoA
-
high activity
-
-
?
linear long-chain alcohol + oleoyl-CoA
?
-
-
-
?
linear long-chain alcohol + palmitoleoyl-CoA
?
-
-
-
?
linear long-chain alcohol + palmitoyl-CoA
?
-
-
-
?
linear long-chain alcohol + stearoyl-CoA
?
-
-
-
?
linolenoyl-CoA + decanol
decyl linolenate + CoA
-
-
-
?
linolenoyl-CoA + docosanol
docosyl linolenate + CoA
-
-
-
?
linolenoyl-CoA + docosenol
docosenyl linolenate + CoA
-
-
-
?
linolenoyl-CoA + dodecanol
dodecyl linolenate + CoA
-
-
-
?
linolenoyl-CoA + eicosanol
eicosanyl linolenate + CoA
-
-
-
?
linolenoyl-CoA + eicosenol
eicosenyl linolenate + CoA
-
-
-
?
linolenoyl-CoA + hexadecanol
hexadecyl linolenate + CoA
-
-
-
?
linolenoyl-CoA + hexadecenol
hexadecenyl linolenate + CoA
-
-
-
?
linolenoyl-CoA + linolenyl alcohol
linolenyl linolenate + CoA
-
-
-
?
linolenoyl-CoA + linoleyl alcohol
linoleyl linolenate + CoA
-
-
-
?
linolenoyl-CoA + octadecanol
octadecyl linolenate + CoA
-
-
-
?
linolenoyl-CoA + octadecenol
octadecenyl linolenate + CoA
-
-
-
?
linolenoyl-CoA + phytol
phytyl linolenate + CoA
-
-
-
?
linolenoyl-CoA + ricinoleyl alcohol
ricinoleyl linolenate + CoA
-
-
-
?
linolenoyl-CoA + tetracosanol
tetracosyl linolenate + CoA
-
-
-
?
linolenoyl-CoA + tetracosenol
tetracosenyl linolenate + CoA
-
-
-
?
linolenoyl-CoA + tetradecanol
tetradecyl linolenate + CoA
-
-
-
?
linoleoyl-CoA + decanol
decyl linoleate + CoA
-
-
-
?
linoleoyl-CoA + docosanol
docosyl linoleate + CoA
-
-
-
?
linoleoyl-CoA + docosenol
docosenyl linoleate + CoA
-
-
-
?
linoleoyl-CoA + dodecanol
dodecyl linoleate + CoA
-
high activity
-
-
?
linoleoyl-CoA + dodecanol
dodecyl linolenate + CoA
-
-
-
?
linoleoyl-CoA + eicosanol
eicosanyl linoleate + CoA
-
-
-
?
linoleoyl-CoA + eicosenol
eicosenyl linoleate + CoA
-
-
-
?
linoleoyl-CoA + hexadecanol
hexadecanyl linoleate + CoA
-
high activity
-
-
?
linoleoyl-CoA + hexadecanol
hexadecyl linoleate + CoA
-
-
-
?
linoleoyl-CoA + hexadecenol
hexadecenyl linoleate + CoA
-
-
-
?
linoleoyl-CoA + linolenyl alcohol
linolenyl linoleate + CoA
-
-
-
?
linoleoyl-CoA + linoleyl alcohol
linoleyl linoleate + CoA
-
-
-
?
linoleoyl-CoA + octadecanol
octadecyl linoleate + CoA
-
-
-
?
linoleoyl-CoA + octadecenol
octadecenyl linoleate + CoA
-
-
-
?
linoleoyl-CoA + phytol
phytyl linoleate + CoA
-
-
-
?
linoleoyl-CoA + ricinoleyl alcohol
ricinoleyl linoleate + CoA
-
-
-
?
linoleoyl-CoA + tetracosanol
tetracosyl linoleate + CoA
-
-
-
?
linoleoyl-CoA + tetracosenol
tetracosenyl linoleate + CoA
-
-
-
?
linoleoyl-CoA + tetradecanol
tetradecyl linoleate + CoA
myristoyl-CoA + (9Z)-hexadec-9-en-1-ol
(9Z)-hexadec-9-en-1-yl tetradecanoate + CoA
-
-
-
?
myristoyl-CoA + 11-cis-retinol
11-cis-retinyl myristate + CoA
preferred substrate
-
-
?
myristoyl-CoA + 13-cis-retinol
13-cis-retinyl myristate + CoA
-
-
-
?
myristoyl-CoA + 9-cis-retinol
9-cis-retinyl myristate + CoA
-
-
-
?
myristoyl-CoA + all-trans-retinol
all-trans-retinyl myristate + CoA
-
-
-
?
myristoyl-CoA + decanol
decyl myristate + CoA
high activity
-
-
?
myristoyl-CoA + docosanol
docosyl myristate + CoA
low activity
-
-
?
myristoyl-CoA + docosenol
docosenyl myristate + CoA
myristoyl-CoA + dodecan-1-ol
dodecan-1-yl myristate + CoA
myristoyl-CoA + dodecanol
dodecyl myristate + CoA
high activity
-
-
?
myristoyl-CoA + eicosanol
eicosanyl myristate + CoA
low activity
-
-
?
myristoyl-CoA + eicosenol
eicosenyl myristate + CoA
myristoyl-CoA + hexadecan-1-ol
?
-
-
-
?
myristoyl-CoA + hexadecan-1-ol
hexadecyl myristate + CoA
-
-
-
?
myristoyl-CoA + hexadecanol
CoA + hexadecyl myristate
myristoyl-CoA + hexadecanol
hexadecanyl myristate + CoA
-
high activity
-
-
?
myristoyl-CoA + hexadecanol
hexadecyl myristate + CoA
high activity
-
-
?
myristoyl-CoA + hexadecenol
hexadecenyl myristate + CoA
myristoyl-CoA + linolenyl alcohol
linolenoyl myristate + CoA
-
high activity
-
-
?
myristoyl-CoA + linolenyl alcohol
linolenyl myristate + CoA
high activity
-
-
?
myristoyl-CoA + linoleyl alcohol
linoleoyl myristate + CoA
-
high activity
-
-
?
myristoyl-CoA + linoleyl alcohol
linoleyl myristate + CoA
high activity
-
-
?
myristoyl-CoA + octadecanol
octadecyl myristate + CoA
myristoyl-CoA + octadecenol
octadecenyl myristate + CoA
myristoyl-CoA + phytol
phytyl myristate + CoA
myristoyl-CoA + ricinoleyl alcohol
ricinoleyl myristate + CoA
-
-
-
?
myristoyl-CoA + tetracosanol
tetracosyl myristate + CoA
very low activity
-
-
?
myristoyl-CoA + tetracosenol
tetracosenyl myristate + CoA
myristoyl-CoA + tetradecan-1-ol
tetradecyl myristate + CoA
-
-
-
?
myristoyl-CoA + tetradecanol
myristyl myristate + CoA
100% conversion efficiency
-
-
?
myristoyl-CoA + tetradecanol
tetradecanyl myristate + CoA
-
-
-
?
myristoyl-CoA + tetradecanol
tetradecyl myristate + CoA
highest activity
-
-
?
nonan-1-ol + palmitoyl-CoA
CoA + nonyl palmitate
octadecatrienoyl-CoA + hexadecan-1-ol
?
-
-
-
?
octadecatrienoyl-CoA + hexadecanol
CoA + hexadecyl octadecatrienoate
-
-
-
?
octadecenoyl-CoA + dodecanol
dodecanyl octadecanoate + CoA
-
-
-
-
ir
octanoyl-CoA + hexadecan-1-ol
?
-
-
-
?
octanoyl-CoA + hexadecanol
CoA + hexadecyl octanoate
-
-
-
?
oleoyl-CoA + (9Z)-hexadec-9-en-1-ol
CoA + (9Z)-hexadec-9-en-1-yl (9Z)-octadec-9-enoate
-
-
-
?
oleoyl-CoA + 1,2-dipalmitoyl-sn-glycerol
CoA + 1,2-dipalmitoyl-3-oleoyl-sn-glycerol
-
-
-
-
?
oleoyl-CoA + 1-decanol
CoA + decyl oleate
-
-
-
?
oleoyl-CoA + 1-octadecanol
CoA + octadecyl oleate
-
-
-
?
oleoyl-CoA + cetyl alcohol
CoA + cetyl oleate
-
-
-
?
oleoyl-CoA + decanol
CoA + decyl oleate
-
-
-
?
oleoyl-CoA + decanol
decyl oleate + CoA
-
-
-
?
oleoyl-CoA + docosanol
docosyl oleate + CoA
-
-
-
?
oleoyl-CoA + docosenol
docosenyl oleate + CoA
-
-
-
?
oleoyl-CoA + dodecanol
dodecyl oleate + CoA
high activity
-
-
?
oleoyl-CoA + eicosanol
CoA + icosyl (9Z)-octadec-9-enoate
-
-
-
?
oleoyl-CoA + eicosanol
eicosanyl oleate + CoA
low activity
-
-
?
oleoyl-CoA + eicosenol
eicosenyl oleate + CoA
high activity
-
-
?
oleoyl-CoA + hexadecanol
hexadecyl oleate + CoA
-
-
-
?
oleoyl-CoA + hexadecenol
hexadecenyl oleate + CoA
-
-
-
?
oleoyl-CoA + linolenyl alcohol
linolenyl oleate + CoA
high activity
-
-
?
oleoyl-CoA + linoleyl alcohol
linoleyl oleate + CoA
high activity
-
-
?
oleoyl-CoA + octadecanol
octadecyl oleate + CoA
-
-
-
?
oleoyl-CoA + octadecenol
octadecenyl oleate + CoA
-
-
-
?
oleoyl-CoA + oleic alcohol
CoA + (9Z)-octadec-9-en-1-yl (9Z)-octadec-9-enoate
-
-
-
?
oleoyl-CoA + phytol
phytyl oleate + CoA
-
-
-
?
oleoyl-CoA + ricinoleyl alcohol
ricinoleyl oleate + CoA
-
-
-
?
oleoyl-CoA + tetracosanol
tetracosyl oleate + CoA
-
-
-
?
oleoyl-CoA + tetracosenol
tetracosenyl oleate + CoA
-
-
-
?
oleoyl-CoA + tetradecanol
tetradecyl oleate + CoA
oleyl-CoA + oleyl alcohol
oleyl oleate + CoA
-
-
-
-
?
palmitoleoyl-CoA + cetyl alcohol
CoA + cetyl palmitoleate
-
-
-
?
palmitoleoyl-CoA + tetradecanol
tetradecyl (9Z)-hexadec-9-enoate + CoA
enzyme shows preference towards myristic acid and palmitoleyl-CoA
-
-
?
palmitoleyl alcohol + oleoyl-CoA
CoA + palmitoleyl oleate
-
-
-
?
palmitoyl-CoA + 1,2-dipalmitin
?
-
-
-
-
?
palmitoyl-CoA + 1,2-dipalmitoyl-sn-glycerol
?
-
high activity
-
-
?
palmitoyl-CoA + 1,2-hexadecandiol
?
-
-
-
?
palmitoyl-CoA + 1-hexadecanol
?
-
-
-
-
?
palmitoyl-CoA + 1-hexadecanol
palmitic acid hexadecyl ester + CoA
-
highest activity
-
-
?
palmitoyl-CoA + 11-cis-retinol
11-cis-retinyl palmitate + CoA
-
-
-
-
?
palmitoyl-CoA + all-trans-retinol
?
-
-
-
?
palmitoyl-CoA + butanol
butyl palmitate + CoA
50% of the rate with decanol
-
-
?
palmitoyl-CoA + cetyl alcohol
CoA + cetyl palmitate
-
-
-
?
palmitoyl-CoA + decanol
decyl palmitate + CoA
palmitoyl-CoA + dioleoylglycerol
?
-
-
-
?
palmitoyl-CoA + docosanol
docosyl palmitate + CoA
low activity
-
-
?
palmitoyl-CoA + docosenol
docosenyl palmitate + CoA
high activity
-
-
?
palmitoyl-CoA + dodecanol
CoA + dodecyl palmitate
-
-
-
-
?
palmitoyl-CoA + dodecanol
dodecyl palmitate + CoA
palmitoyl-CoA + eicosanol
eicosanyl palmitate + CoA
low activity
-
-
?
palmitoyl-CoA + eicosenol
eicosenyl palmitate + CoA
palmitoyl-CoA + ethanol
ethyl palmitate + CoA
24% of the rate with decanol
-
-
?
palmitoyl-CoA + hexadecan-1-ol
CoA + hexadecyl palmitate
-
-
-
?
palmitoyl-CoA + hexadecanol
CoA + hexadecyl palmitate
palmitoyl-CoA + hexadecanol
hexadecanyl palmitate + CoA
palmitoyl-CoA + hexadecanol
hexadecyl palmitate + CoA
palmitoyl-CoA + hexadecanol
palmityl palmitate + CoA
about 25% conversion efficiency compared to myristoyl-CoA plus tetradecanol
-
-
?
palmitoyl-CoA + hexadecenol
hexadecenyl palmitate + CoA
palmitoyl-CoA + hexanol
hexyl palmitate + CoA
87% of the rate with decanol
-
-
?
palmitoyl-CoA + isoamyl alcohol
isoamyl palmitate + CoA
57% of the rate with decanol
-
-
?
palmitoyl-CoA + linolenyl alcohol
linolenyl palmitate + CoA
-
-
-
?
palmitoyl-CoA + linoleyl alcohol
linoleyl palmitate + CoA
-
-
-
?
palmitoyl-CoA + long-chain fatty alcohol
CoA + long-chain palmitoyl ester
-
-
-
-
?
palmitoyl-CoA + monooleoylglycerol
?
-
-
-
?
palmitoyl-CoA + octadecanol
CoA + octadecyl palmitate
-
-
-
-
?
palmitoyl-CoA + octadecanol
octadecyl palmitate + CoA
palmitoyl-CoA + octadecenol
octadecenyl palmitate + CoA
palmitoyl-CoA + octanol
octyl palmitate + CoA
79% of the rate with decanol
-
-
?
palmitoyl-CoA + palmitoleyl alcohol
?
-
-
-
-
?
palmitoyl-CoA + phytol
phytyl palmitate + CoA
palmitoyl-CoA + ricinoleyl alcohol
ricinoleyl palmitate + CoA
high activity
-
-
?
palmitoyl-CoA + tetracosanol
tetracosyl palmitate + CoA
very low activity
-
-
?
palmitoyl-CoA + tetracosenol
tetracosenyl palmitate + CoA
high activity
-
-
?
palmitoyl-CoA + tetradecanol
CoA + tetradecyl palmitate
-
-
-
-
?
palmitoyl-CoA + tetradecanol
tetradecyl palmitate
-
-
-
?
palmitoyl-CoA + tetradecanol
tetradecyl palmitate + CoA
phenol + palmitoyl-CoA
phenyl palmitate + CoA
4.1% the rate of hexacedanol
-
-
?
phenylethanol + palmitoyl-CoA
phenylethyl palmitate + CoA
99% the rate of hexacedanol
-
-
?
phytanoyl-CoA + phytol
?
-
-
-
-
?
ricinoleyl-CoA + decanol
decyl ricinoleate + CoA
-
-
-
?
ricinoleyl-CoA + docosanol
docosyl ricinoleate + CoA
-
-
-
?
ricinoleyl-CoA + docosenol
docosenyl ricinoleate + CoA
-
-
-
?
ricinoleyl-CoA + dodecanol
dodecyl ricinoleate + CoA
-
-
-
?
ricinoleyl-CoA + eicosanol
eicosanyl ricinoleate + CoA
-
-
-
?
ricinoleyl-CoA + eicosenol
eicosenyl ricinoleate + CoA
-
-
-
?
ricinoleyl-CoA + hexadecanol
hexadecyl ricinoleate + CoA
-
-
-
?
ricinoleyl-CoA + hexadecenol
hexadecenyl ricinoleate + CoA
-
-
-
?
ricinoleyl-CoA + linolenyl alcohol
linolenyl ricinoleate + CoA
-
-
-
?
ricinoleyl-CoA + linoleyl alcohol
linoleyl ricinoleate + CoA
-
-
-
?
ricinoleyl-CoA + octadecanol
octadecyl ricinoleate + CoA
-
-
-
?
ricinoleyl-CoA + octadecenol
octadecenyl ricinoleate + CoA
-
-
-
?
ricinoleyl-CoA + phytol
phytyl ricinoleate + CoA
-
-
-
?
ricinoleyl-CoA + ricinoleyl alcohol
ricinoleyl ricinoleate + CoA
-
-
-
?
ricinoleyl-CoA + tetracosanol
tetracosyl ricinoleate + CoA
-
-
-
?
ricinoleyl-CoA + tetracosenol
tetracosenyl ricinoleate + CoA
-
-
-
?
ricinoleyl-CoA + tetradecanol
tetradecyl ricinoleate + CoA
-
-
-
?
stearoyl-CoA + cetyl alcohol
CoA + cetyl stearate
-
-
-
?
stearoyl-CoA + decanol
decyl stearate + CoA
-
-
-
?
stearoyl-CoA + docosanol
docosyl stearate + CoA
-
-
-
?
stearoyl-CoA + docosenol
docosenyl stearate + CoA
-
-
-
?
stearoyl-CoA + dodecanol
dodecyl stearate + CoA
-
-
-
?
stearoyl-CoA + eicosanol
eicosanyl stearate + CoA
low activity
-
-
?
stearoyl-CoA + eicosenol
eicosenyl stearate + CoA
high activity
-
-
?
stearoyl-CoA + hexadecan-1-ol
?
-
-
-
?
stearoyl-CoA + hexadecanol
CoA + stearoyl hexadecanate
-
-
-
?
stearoyl-CoA + hexadecanol
hexadecyl stearate + CoA
-
-
-
?
stearoyl-CoA + hexadecenol
hexadecenyl stearate + CoA
-
-
-
?
stearoyl-CoA + linolenyl alcohol
linolenyl stearate + CoA
-
-
-
?
stearoyl-CoA + linoleyl alcohol
linoleyl stearate + CoA
-
-
-
?
stearoyl-CoA + octadecanol
octadecyl stearate + CoA
-
-
-
?
stearoyl-CoA + octadecenol
octadecenyl stearate + CoA
-
-
-
?
stearoyl-CoA + phytol
phytyl stearate + CoA
-
-
-
?
stearoyl-CoA + ricinoleyl alcohol
ricinoleyl stearate + CoA
-
-
-
?
stearoyl-CoA + tetracosanol
tetracosyl stearate + CoA
-
-
-
?
stearoyl-CoA + tetracosenol
tetracosenyl stearate + CoA
-
-
-
?
stearoyl-CoA + tetradecanol
tetradecyl stearate + CoA
tetradecanol + palmitoyl-CoA
tetradecanyl palmitate + CoA
undecanol + palmitoyl-CoA
undecanyl palmitate + CoA
undecanol + palmitoyl-CoA
undecanyl palmitate + CoASH
additional information
?
-
1,2-hexadecandiol + palmitoyl-CoA

?
-
-
-
?
1,2-hexadecandiol + palmitoyl-CoA
?
-
-
-
-
?
1-hexadecanethiol + palmitoyl-CoA

palmitic acid hexadecyl thio ester + CoA
-
-
-
-
?
1-hexadecanethiol + palmitoyl-CoA
palmitic acid hexadecyl thio ester + CoA
-
mutant strain ADP1acr1omegaKm
-
-
?
1-hexadecanol + palmitoyl-CoA

CoA + hexadecylpalmitate
-
-
-
?
1-hexadecanol + palmitoyl-CoA
CoA + hexadecylpalmitate
-
-
-
-
?
1-hexadecanol + palmitoyl-CoA

palmitic acid hexadecyl ester + CoA
-
best substrate
-
-
?
1-hexadecanol + palmitoyl-CoA
palmitic acid hexadecyl ester + CoA
-
mutant strain ADP1acr1omegaKm
-
-
?
1-S-monopalmitoyloctanedithiol + palmitoyl-CoA

1,8-S-dipalmitoyloctanedithiol + CoA
-
-
-
-
?
1-S-monopalmitoyloctanedithiol + palmitoyl-CoA
1,8-S-dipalmitoyloctanedithiol + CoA
-
mutant strain ADP1acr1omegaKm
-
-
?
2 1,8-octanedithiol + 3 palmitoyl-CoA

1-S-monopalmitoyloctanedithiol + 1,8-S-dipalmitoyloctanedithiol + 3 CoA
-
-
1-S-monopalmitoyloctanedithiol is the main product
-
?
2 1,8-octanedithiol + 3 palmitoyl-CoA
1-S-monopalmitoyloctanedithiol + 1,8-S-dipalmitoyloctanedithiol + 3 CoA
-
mutant strain ADP1acr1omegaKm
1-S-monopalmitoyloctanedithiol is the main product
-
?
2 1,8-octanedithiol + 3 palmitoyl-CoA
1-S-monopalmitoyloctanedithiol + 1,8-S-dipalmitoyloctanedithiol + 3 CoA
-
-
1-S-monopalmitoyloctanedithiol is the main product
-
?
2-phenylethanol + palmitoyl-CoA

2-phenylethyl palmitate + CoA
-
-
-
?
2-phenylethanol + palmitoyl-CoA
2-phenylethyl palmitate + CoA
-
-
-
?
acyl-CoA + a long-chain alcohol

CoA + a long-chain ester
-
-
-
?
acyl-CoA + a long-chain alcohol
CoA + a long-chain ester
-
-
-
?
acyl-CoA + a long-chain alcohol
CoA + a long-chain ester
-
-
-
?
acyl-CoA + a long-chain alcohol
CoA + a long-chain ester
-
-
-
-
?
acyl-CoA + a long-chain alcohol
CoA + a long-chain ester
-
-
-
?
acyl-CoA + a long-chain alcohol
CoA + a long-chain ester
-
-
-
-
?
acyl-CoA + a long-chain alcohol
CoA + a long-chain ester
-
-
-
-
?
acyl-CoA + a long-chain alcohol
CoA + a long-chain ester
-
-
-
-
?
acyl-CoA + a long-chain alcohol
CoA + a long-chain ester
-
-
-
-
?
acyl-CoA + a long-chain alcohol
CoA + a long-chain ester
-
-
-
?
acyl-CoA + long-chain diacylglycerol

CoA + long-chain triacylglycerol
-
-
-
-
?
acyl-CoA + long-chain diacylglycerol
CoA + long-chain triacylglycerol
-
-
-
?
acyl-CoA + long-chain fatty alcohol

CoA + long-chain fatty ester
-
-
-
-
?
acyl-CoA + long-chain fatty alcohol
CoA + long-chain fatty ester
-
-
-
?
acyl-CoA + long-chain fatty alcohol
CoA + long-chain fatty ester
-
-
-
-
?
dodecan-1-ol + palmitoyl-CoA

CoA + dodecanyl palmitate
-
-
-
?
dodecan-1-ol + palmitoyl-CoA
CoA + dodecanyl palmitate
-
-
-
?
dodecan-1-ol + palmitoyl-CoA
CoA + dodecanyl palmitate
-
-
-
?
dodecanol + palmitoyl-CoA

dodecanyl palmitate + CoA
-
best substrate
-
-
?
dodecanol + palmitoyl-CoA
dodecanyl palmitate + CoA
-
and undecanol, best substrates for both isoforms Ma1 and Ma2
-
-
?
dodecanol + palmitoyl-CoA
dodecanyl palmitate + CoA
-
-
-
-
?
dodecanol + palmitoyl-CoA
dodecanyl palmitate + CoA
-
-
-
-
?
dodecanol + palmitoyl-CoA
dodecanyl palmitate + CoA
-
-
-
-
?
eicosenoyl-CoA + docosenol

docosenyl eicosenoate + CoA
-
-
-
?
eicosenoyl-CoA + docosenol
docosenyl eicosenoate + CoA
-
-
-
ir
eicosenoyl-CoA + docosenol
docosenyl eicosenoate + CoA
-
high activity
-
-
?
eicosenoyl-CoA + dodecanol

dodecyl eicosenoate + CoA
-
-
-
?
eicosenoyl-CoA + dodecanol
dodecyl eicosenoate + CoA
-
high activity
-
-
?
eicosenoyl-CoA + octadecenol

octadecenyl eicosenoate + CoA
-
-
-
?
eicosenoyl-CoA + octadecenol
octadecenyl eicosenoate + CoA
best substrates
-
-
?
ethanol + palmitoyl-CoA

ethyl palmitate + CoA
-
-
-
?
ethanol + palmitoyl-CoA
ethyl palmitate + CoA
-
-
-
?
hexadecan-1-ol + palmitoyl-CoA

CoA + hexadecyl palmitate
-
-
-
?
hexadecan-1-ol + palmitoyl-CoA
CoA + hexadecyl palmitate
-
-
-
?
hexadecan-1-ol + palmitoyl-CoA
CoA + hexadecyl palmitate
-
-
-
?
hexadecanol + palmitoyl-CoA

hexadecanyl palmitate + CoA
-
-
-
-
?
hexadecanol + palmitoyl-CoA
hexadecanyl palmitate + CoA
-
-
-
-
?
hexadecanol + palmitoyl-CoA
hexadecanyl palmitate + CoA
-
-
-
-
?
hexadecanol + palmitoyl-CoA
hexadecanyl palmitate + CoA
-
-
-
-
?
hexan-1-ol + palmitoyl-CoA

hexyl palmitate + CoA
-
-
-
?
hexan-1-ol + palmitoyl-CoA
hexyl palmitate + CoA
-
-
-
?
isoamyl alcohol + palmitoyl-CoA

isoamyl palmitate + CoA
-
-
-
?
isoamyl alcohol + palmitoyl-CoA
isoamyl palmitate + CoA
-
-
-
?
lauroyl-CoA + hexadecanol

CoA + hexadecyl laurate
-
-
-
?
lauroyl-CoA + hexadecanol
CoA + hexadecyl laurate
best acyl-CoA substrate
-
-
?
lauroyl-CoA + tetradecanol

tetradecyl laurate + CoA
-
-
-
?
lauroyl-CoA + tetradecanol
tetradecyl laurate + CoA
-
-
-
?
linoleoyl-CoA + tetradecanol

tetradecyl linoleate + CoA
-
-
-
?
linoleoyl-CoA + tetradecanol
tetradecyl linoleate + CoA
-
high activity
-
-
?
linoleoyl-CoA + tetradecanol
tetradecyl linoleate + CoA
-
second highest activity
-
-
?
myristoyl-CoA + docosenol

docosenyl myristate + CoA
high activity
-
-
?
myristoyl-CoA + docosenol
docosenyl myristate + CoA
-
-
-
-
?
myristoyl-CoA + dodecan-1-ol

dodecan-1-yl myristate + CoA
-
-
-
?
myristoyl-CoA + dodecan-1-ol
dodecan-1-yl myristate + CoA
-
-
-
?
myristoyl-CoA + eicosenol

eicosenyl myristate + CoA
high activity
-
-
?
myristoyl-CoA + eicosenol
eicosenyl myristate + CoA
-
highest activity
-
-
?
myristoyl-CoA + hexadecanol

CoA + hexadecyl myristate
-
-
-
?
myristoyl-CoA + hexadecanol
CoA + hexadecyl myristate
preferred acyl-CoA substrate
-
-
?
myristoyl-CoA + hexadecenol

hexadecenyl myristate + CoA
high activity
-
-
?
myristoyl-CoA + hexadecenol
hexadecenyl myristate + CoA
-
high activity
-
-
?
myristoyl-CoA + octadecanol

octadecyl myristate + CoA
high activity
-
-
?
myristoyl-CoA + octadecanol
octadecyl myristate + CoA
-
high activity
-
-
?
myristoyl-CoA + octadecenol

octadecenyl myristate + CoA
high activity
-
-
?
myristoyl-CoA + octadecenol
octadecenyl myristate + CoA
-
high activity
-
-
?
myristoyl-CoA + phytol

phytyl myristate + CoA
-
-
-
?
myristoyl-CoA + phytol
phytyl myristate + CoA
-
-
-
-
?
myristoyl-CoA + tetracosenol

tetracosenyl myristate + CoA
-
-
-
?
myristoyl-CoA + tetracosenol
tetracosenyl myristate + CoA
-
-
-
-
?
nonan-1-ol + palmitoyl-CoA

CoA + nonyl palmitate
-
-
-
?
nonan-1-ol + palmitoyl-CoA
CoA + nonyl palmitate
-
-
-
?
nonan-1-ol + palmitoyl-CoA
CoA + nonyl palmitate
-
-
-
?
oleoyl-CoA + tetradecanol

tetradecyl oleate + CoA
high activity
-
-
?
oleoyl-CoA + tetradecanol
tetradecyl oleate + CoA
-
high activity
-
-
?
palmitoyl-CoA + decanol

decyl palmitate + CoA
best substrate
-
-
?
palmitoyl-CoA + decanol
decyl palmitate + CoA
-
-
-
?
palmitoyl-CoA + dodecanol

dodecyl palmitate + CoA
-
-
-
?
palmitoyl-CoA + dodecanol
dodecyl palmitate + CoA
-
-
-
-
?
palmitoyl-CoA + eicosenol

eicosenyl palmitate + CoA
high activity
-
-
?
palmitoyl-CoA + eicosenol
eicosenyl palmitate + CoA
-
high activity
-
-
?
palmitoyl-CoA + hexadecanol

CoA + hexadecyl palmitate
-
-
-
?
palmitoyl-CoA + hexadecanol
CoA + hexadecyl palmitate
-
-
-
-
?
palmitoyl-CoA + hexadecanol
CoA + hexadecyl palmitate
-
-
-
-
?
palmitoyl-CoA + hexadecanol
CoA + hexadecyl palmitate
-
-
-
?
palmitoyl-CoA + hexadecanol
CoA + hexadecyl palmitate
-
-
-
?
palmitoyl-CoA + hexadecanol

hexadecanyl palmitate + CoA
-
-
-
?
palmitoyl-CoA + hexadecanol
hexadecanyl palmitate + CoA
-
high activity
-
-
?
palmitoyl-CoA + hexadecanol

hexadecyl palmitate + CoA
79% of the rate with decanol
-
-
?
palmitoyl-CoA + hexadecanol
hexadecyl palmitate + CoA
-
-
-
?
palmitoyl-CoA + hexadecenol

hexadecenyl palmitate + CoA
-
-
-
?
palmitoyl-CoA + hexadecenol
hexadecenyl palmitate + CoA
-
-
-
-
?
palmitoyl-CoA + octadecanol

octadecyl palmitate + CoA
-
-
-
?
palmitoyl-CoA + octadecanol
octadecyl palmitate + CoA
-
high activity
-
-
?
palmitoyl-CoA + octadecanol
octadecyl palmitate + CoA
-
lowest activity
-
-
?
palmitoyl-CoA + octadecenol

octadecenyl palmitate + CoA
-
-
-
?
palmitoyl-CoA + octadecenol
octadecenyl palmitate + CoA
-
high activity
-
-
?
palmitoyl-CoA + phytol

phytyl palmitate + CoA
-
-
-
-
?
palmitoyl-CoA + phytol
phytyl palmitate + CoA
-
-
-
?
palmitoyl-CoA + tetradecanol

tetradecyl palmitate + CoA
-
-
-
?
palmitoyl-CoA + tetradecanol
tetradecyl palmitate + CoA
-
high activity
-
-
?
stearoyl-CoA + tetradecanol

tetradecyl stearate + CoA
-
-
-
?
stearoyl-CoA + tetradecanol
tetradecyl stearate + CoA
-
high activity
-
-
?
tetradecanol + palmitoyl-CoA

tetradecanyl palmitate + CoA
-
-
-
-
?
tetradecanol + palmitoyl-CoA
tetradecanyl palmitate + CoA
-
best substrate
-
-
?
tetradecanol + palmitoyl-CoA
tetradecanyl palmitate + CoA
-
best substrate
-
-
?
undecanol + palmitoyl-CoA

undecanyl palmitate + CoA
-
-
-
-
?
undecanol + palmitoyl-CoA
undecanyl palmitate + CoA
-
and dodecanol, best substrates for both isoforms Ma1 and Ma2
-
-
?
undecanol + palmitoyl-CoA
undecanyl palmitate + CoA
-
and decanol, best substrates
-
-
?
undecanol + palmitoyl-CoA

undecanyl palmitate + CoASH
-
-
-
-
?
undecanol + palmitoyl-CoA
undecanyl palmitate + CoASH
-
-
-
-
?
additional information

?
-
-
key enzyme in the biosynthesis of neutral lipid storage compounds, triacylglycerols and wax esters, overview
-
-
?
additional information
?
-
-
a bifunctional enzyme also catalyzing the reaction of EC 2.3.1.20
-
-
?
additional information
?
-
-
WS/DGAT is a very unspecific enzyme and accepts a wide variety of hydrophobic substrates, although also several compounds, e.g. hydroxylamine, sugars, and astaxanthine, do not serve as substrates, substrate specificity, overview. The highly conserved HHXXXDG motif is located at the enzyme's active site, it possesses two histidine residues that are essential for catalysis
-
-
?
additional information
?
-
-
the order of addition, i.e.the substrate that the protein is incubated with during the first minute while the background absorbance is measured, has a significant impact on the rate of reaction. No substrate: hexanol
-
-
?
additional information
?
-
the enzyme has high preference for C18 substrates
-
-
-
additional information
?
-
no substrate: resorcinol
-
-
?
additional information
?
-
the enzyme has high preference for C18 substrates
-
-
-
additional information
?
-
-
the bifunctional wax ester synthase/acyl coenzyme A (acyl-CoA):diacylglycerol acyltransferase from Acinetobacter sp. strain ADP1 mediates the biosyntheses of wax esters and triacylglycerols
-
-
?
additional information
?
-
-
the bifunctional enzyme catalyzes the reactions of the diacylglycerol transferase, EC 2.3.1.20, and of the wax synthase, EC 2.3.1.75, substrate specificity of the wax ester synthase activity with alkanethiols as alternative acyl acceptors
-
-
?
additional information
?
-
-
the bifunctional wax ester synthase/acyl coenzyme A (acyl-CoA):diacylglycerol acyltransferase from Acinetobacter sp. strain ADP1 mediates the biosyntheses of wax esters and triacylglycerols
-
-
?
additional information
?
-
-
the bifunctional enzyme catalyzes the reactions of the diacylglycerol transferase, EC 2.3.1.20, and of the wax synthase, EC 2.3.1.75, substrate specificity of the wax ester synthase activity with alkanethiols as alternative acyl acceptors
-
-
?
additional information
?
-
-
the enzyme plays the key role in the biosynthesis of triacylglycerols and wax esters, overview
-
-
?
additional information
?
-
-
acyl acceptor specificities of isozymes AtfA1 and AtfA2 from A. borkumensis SK2 for glycerol and acylglycerols, overview
-
-
?
additional information
?
-
-
WSD1, a member of the bifunctional wax ester synthase/diacylglycerol acyltransferase gene family, plays a key role in wax ester synthesis in Arabidopsis
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-
?
additional information
?
-
-
the enzyme has a high level of wax synthase activity and approximately 10fold lower level of diacylglycerol acyltransferase activity
-
-
?
additional information
?
-
isoform WSD2 has a high specificity toward shorter chain length fatty acids and alcohols and readily utilize C14 fatty acid and C14 alcohol as substrates, show low activity with C16 substrates, and almost negligible reaction toward C18 substrates
-
-
-
additional information
?
-
isoform WSD2 has a high specificity toward shorter chain length fatty acids and alcohols and readily utilize C14 fatty acid and C14 alcohol as substrates, show low activity with C16 substrates, and almost negligible reaction toward C18 substrates
-
-
-
additional information
?
-
-
isoform WSD2 has a high specificity toward shorter chain length fatty acids and alcohols and readily utilize C14 fatty acid and C14 alcohol as substrates, show low activity with C16 substrates, and almost negligible reaction toward C18 substrates
-
-
-
additional information
?
-
isoform WSD5 has a high specificity toward shorter chain length fatty acids and alcohols and readily utilize C14 fatty acid and C14 alcohol as substrates, show low activity with C16 substrates, and almost negligible reaction toward C18 substrates
-
-
-
additional information
?
-
isoform WSD5 has a high specificity toward shorter chain length fatty acids and alcohols and readily utilize C14 fatty acid and C14 alcohol as substrates, show low activity with C16 substrates, and almost negligible reaction toward C18 substrates
-
-
-
additional information
?
-
-
isoform WSD5 has a high specificity toward shorter chain length fatty acids and alcohols and readily utilize C14 fatty acid and C14 alcohol as substrates, show low activity with C16 substrates, and almost negligible reaction toward C18 substrates
-
-
-
additional information
?
-
no activity with stearoyl-CoA and octadecanol as substrates
-
-
-
additional information
?
-
no activity with stearoyl-CoA and octadecanol as substrates
-
-
-
additional information
?
-
-
no activity with stearoyl-CoA and octadecanol as substrates
-
-
-
additional information
?
-
prefers monounsaturated and polyunsaturated C18:1 and C18:2 fatty alcohols over C18:0, and prefers 20:1 fatty alcohol over C20:0. Enzyme prefers shorter chain fatty acyl-CoA substrates and does not discriminate between monounsaturated and polyunsaturated fatty acyl CoA substrates. Enzyme also uses 10, 15, and 20 carbon isoprenoid alcohols
-
-
?
additional information
?
-
-
the enzyme plays an important role in lipid metabolism in human skin, overview
-
-
?
additional information
?
-
the enzyme plays an important role in lipid metabolism in human skin, overview
-
-
?
additional information
?
-
-
the multifunctional enzyme plays an important role in lipid metabolism in human skin
-
-
?
additional information
?
-
the multifunctional enzyme plays an important role in lipid metabolism in human skin
-
-
?
additional information
?
-
AWAT 1 predominantly esterifies long chain, wax alcohols with acyl-CoA-derived fatty acids to produce wax esters, AWAT1 and AWAT2 have very distinct substrate preferences in terms of alcohol chain length and fatty acyl saturation, overview
-
-
?
additional information
?
-
AWAT 1 predominantly esterifies long chain, wax alcohols with acyl-CoA-derived fatty acids to produce wax esters, AWAT1 and AWAT2 have very distinct substrate preferences in terms of alcohol chain length and fatty acyl saturation, overview
-
-
?
additional information
?
-
AWAT 1 predominantly esterifies long chain, wax alcohols with acyl-CoA-derived fatty acids to produce wax esters, AWAT1 and AWAT2 have very distinct substrate preferences in terms of alcohol chain length and fatty acyl saturation, overview
-
-
?
additional information
?
-
-
AWAT 1 predominantly esterifies long chain, wax alcohols with acyl-CoA-derived fatty acids to produce wax esters, AWAT1 and AWAT2 have very distinct substrate preferences in terms of alcohol chain length and fatty acyl saturation, overview
-
-
?
additional information
?
-
AWAT 2 predominantly esterifies long chain, wax alcohols with acyl-CoA-derived fatty acids to produce wax esters, AWAT1 and AWAT2 have very distinct substrate preferences in terms of alcohol chain length and fatty acyl saturation, overview, no activity of AWAT2 with 1-decanol
-
-
?
additional information
?
-
AWAT 2 predominantly esterifies long chain, wax alcohols with acyl-CoA-derived fatty acids to produce wax esters, AWAT1 and AWAT2 have very distinct substrate preferences in terms of alcohol chain length and fatty acyl saturation, overview, no activity of AWAT2 with 1-decanol
-
-
?
additional information
?
-
AWAT 2 predominantly esterifies long chain, wax alcohols with acyl-CoA-derived fatty acids to produce wax esters, AWAT1 and AWAT2 have very distinct substrate preferences in terms of alcohol chain length and fatty acyl saturation, overview, no activity of AWAT2 with 1-decanol
-
-
?
additional information
?
-
-
AWAT 2 predominantly esterifies long chain, wax alcohols with acyl-CoA-derived fatty acids to produce wax esters, AWAT1 and AWAT2 have very distinct substrate preferences in terms of alcohol chain length and fatty acyl saturation, overview, no activity of AWAT2 with 1-decanol
-
-
?
additional information
?
-
bifunctional enzyme also catalyzing the reaction of EC 2.3.1.20
-
-
?
additional information
?
-
bifunctional enzyme also catalyzing the reaction of EC 2.3.1.20
-
-
?
additional information
?
-
bifunctional enzyme also catalyzing the reaction of EC 2.3.1.20
-
-
?
additional information
?
-
-
bifunctional enzyme also catalyzing the reaction of EC 2.3.1.20
-
-
?
additional information
?
-
substrate specificity of AWAT1, overview, AWAT1 and AWAT2 have very distinct substrate preferences in terms of alcohol chain length and fatty acyl saturation and predominantly esterify long chain alcohols with acyl-CoA-derived fatty acids to produce wax esters, bifunctional enzyme also catalyzing the reaction of EC 2.3.1.20
-
-
?
additional information
?
-
substrate specificity of AWAT1, overview, AWAT1 and AWAT2 have very distinct substrate preferences in terms of alcohol chain length and fatty acyl saturation and predominantly esterify long chain alcohols with acyl-CoA-derived fatty acids to produce wax esters, bifunctional enzyme also catalyzing the reaction of EC 2.3.1.20
-
-
?
additional information
?
-
substrate specificity of AWAT1, overview, AWAT1 and AWAT2 have very distinct substrate preferences in terms of alcohol chain length and fatty acyl saturation and predominantly esterify long chain alcohols with acyl-CoA-derived fatty acids to produce wax esters, bifunctional enzyme also catalyzing the reaction of EC 2.3.1.20
-
-
?
additional information
?
-
-
substrate specificity of AWAT1, overview, AWAT1 and AWAT2 have very distinct substrate preferences in terms of alcohol chain length and fatty acyl saturation and predominantly esterify long chain alcohols with acyl-CoA-derived fatty acids to produce wax esters, bifunctional enzyme also catalyzing the reaction of EC 2.3.1.20
-
-
?
additional information
?
-
substrate specificity of AWAT2, overview, AWAT1 and AWAT2 have very distinct substrate preferences in terms of alcohol chain length and fatty acyl saturation and predominantly esterify long chain alcohols with acyl-CoA-derived fatty acids to produce wax esters, bifunctional enzyme also catalyzing the reaction of EC 2.3.1.20
-
-
?
additional information
?
-
substrate specificity of AWAT2, overview, AWAT1 and AWAT2 have very distinct substrate preferences in terms of alcohol chain length and fatty acyl saturation and predominantly esterify long chain alcohols with acyl-CoA-derived fatty acids to produce wax esters, bifunctional enzyme also catalyzing the reaction of EC 2.3.1.20
-
-
?
additional information
?
-
substrate specificity of AWAT2, overview, AWAT1 and AWAT2 have very distinct substrate preferences in terms of alcohol chain length and fatty acyl saturation and predominantly esterify long chain alcohols with acyl-CoA-derived fatty acids to produce wax esters, bifunctional enzyme also catalyzing the reaction of EC 2.3.1.20
-
-
?
additional information
?
-
-
substrate specificity of AWAT2, overview, AWAT1 and AWAT2 have very distinct substrate preferences in terms of alcohol chain length and fatty acyl saturation and predominantly esterify long chain alcohols with acyl-CoA-derived fatty acids to produce wax esters, bifunctional enzyme also catalyzing the reaction of EC 2.3.1.20
-
-
?
additional information
?
-
-
substrate specificity, overview, a human skin multifunctional O-acyltransferase that catalyzes the synthesis of acylglycerols, waxes, and retinyl esters, overview, the enzyme catalyzes also the reactions of EC 2.3.1.20 and EC 2.3.1.22
-
-
?
additional information
?
-
substrate specificity, overview, a human skin multifunctional O-acyltransferase that catalyzes the synthesis of acylglycerols, waxes, and retinyl esters, overview, the enzyme catalyzes also the reactions of EC 2.3.1.20 and EC 2.3.1.22
-
-
?
additional information
?
-
-
the multifunctional O-acetyltransferase is catalyzing the reactions of the wax synthase, of the diacylglycerol transferase, EC 2.3.1.20, of the monoacylglycerol transferase, EC 2.3.1.22, and of the acyl-CoA:retinol acyltransferase, EC 2.3.1.76, overview
-
-
?
additional information
?
-
the multifunctional O-acetyltransferase is catalyzing the reactions of the wax synthase, of the diacylglycerol transferase, EC 2.3.1.20, of the monoacylglycerol transferase, EC 2.3.1.22, and of the acyl-CoA:retinol acyltransferase, EC 2.3.1.76, overview
-
-
?
additional information
?
-
-
the enzyme is involved in synthesis of isoprenoid wax ester storage compounds, pathway, overview
-
-
?
additional information
?
-
-
substrate profiles of isozymes WS1 and WS2, acyl-CoA specificity of isozyme WS2 with preference for palmitoyl-CoA and broad activity with alcohols of various chain lengths, bifunctional enzyme also catalyzing the reaction of EC 2.3.1.20
-
-
?
additional information
?
-
-
the order of addition, i.e.the substrate that the protein is incubated with during the first minute while the background absorbance is measured, has a significant impact on the rate of reaction. No substrate: hexanol
-
-
?
additional information
?
-
-
the enzyme has high preference for C18 substrates
-
-
-
additional information
?
-
the enzyme shows no diacylglycerol acyltransferase activity
-
-
-
additional information
?
-
-
the enzyme shows no diacylglycerol acyltransferase activity
-
-
-
additional information
?
-
prefers monounsaturated and polyunsaturated C18:1 and C18:2 fatty alcohols over C18:0, and prefers 20:1 fatty alcohol over C20:0. Enzyme prefers shorter chain fatty acyl-CoA substrates and does not discriminate between monounsaturated and polyunsaturated fatty acyl CoA substrates. Enzyme also uses 10, 15, and 20 carbon isoprenoid alcohols
-
-
?
additional information
?
-
-
prefers monounsaturated and polyunsaturated C18:1 and C18:2 fatty alcohols over C18:0, and prefers 20:1 fatty alcohol over C20:0. Enzyme prefers shorter chain fatty acyl-CoA substrates and does not discriminate between monounsaturated and polyunsaturated fatty acyl CoA substrates. Enzyme also uses 10, 15, and 20 carbon isoprenoid alcohols
-
-
?
additional information
?
-
-
DGAT1 is catalyzing the reactions of the monoacylglycerol transferase, EC 2.3.1.22, of the diacylglycerol transferase, EC 2.3.1.20, of the wax synthase, EC 2.3.1.75, and of the acyl-CoA:retinol acyltransferase, EC 2.3.1.76, DGAT2 catalyzes the wax ester synthase reaction, overview
-
-
?
additional information
?
-
the highest activity is observed for 14:0-CoA, 12:0-CoA, and 16:0-CoA in combination with medium chain alcohols (up to 5.2, 3.4, and 3.3 nmol wax esters/min/mg microsomal protein, respectively). Unsaturated alcohols longer than 18C are better utilized by the enzyme in comparison to the saturated ones. Combinations of all tested alcohols with 20:0-CoA, 22:1-CoA, or ricinoleoyl-CoA are poorly utilized by the enzyme, and conjugated acyl-CoAs are not utilized at all
-
-
?
additional information
?
-
-
the highest activity is observed for 14:0-CoA, 12:0-CoA, and 16:0-CoA in combination with medium chain alcohols (up to 5.2, 3.4, and 3.3 nmol wax esters/min/mg microsomal protein, respectively). Unsaturated alcohols longer than 18C are better utilized by the enzyme in comparison to the saturated ones. Combinations of all tested alcohols with 20:0-CoA, 22:1-CoA, or ricinoleoyl-CoA are poorly utilized by the enzyme, and conjugated acyl-CoAs are not utilized at all
-
-
?
additional information
?
-
-
the order of addition, i.e.the substrate that the protein is incubated with during the first minute while the background absorbance is measured, has a significant impact on the rate of reaction. No substrate: hexanol
-
-
?
additional information
?
-
-
the order of addition, i.e.the substrate that the protein is incubated with during the first minute while the background absorbance is measured, has a significant impact on the rate of reaction. No substrate: hexanol
-
-
?
additional information
?
-
substrate specificity, overview
-
-
?
additional information
?
-
-
substrate specificity, overview
-
-
?
additional information
?
-
-
eicosanoyl-CoA can be replaced by stearoyl-CoA or cis-11-eicosenoyl-CoA with equal reactivity
-
-
?
additional information
?
-
-
the purified enzyme AtfG25 shows acyltransferase activity with C12- or C16-acyl-CoA (cf. EC 2.3.1.20), C2 to C18 alcohols (ethanol, butanol, hexanol, octanol, decanol, dodecanol, tetradecanol, hexadecanol, palmitoleyl alcohol, and octadecanol), and dipalmitoyl glycerol. Substrate specificity, overview. The DGAT activity of AtfG25 corresponds to about 70% of itsWS activity
-
-
-
additional information
?
-
the recombinant protein purified from Escherichia coli strain Rosetta (DE3) has substantial wax synthase (WS) and lower diacylglycerol acyltransferase (DGAT) activity. Acyl-CoA substrate specificity, overview. TrWSD4 accepts four linear alcohols as substrates and the highest WS activity is observed for octadecanol (C18:0-OH), which is 2fold higher than the activity using decanol as substrate (C10:0-OH)
-
-
-
additional information
?
-
the recombinant protein purified from Escherichia coli strain Rosetta (DE3) has substantial wax synthase (WS) and lower diacylglycerol acyltransferase (DGAT) activity. Acyl-CoA substrate specificity, overview. TrWSD4 accepts four linear alcohols as substrates and the highest WS activity is observed for octadecanol (C18:0-OH), which is 2fold higher than the activity using decanol as substrate (C10:0-OH)
-
-
-
additional information
?
-
-
the recombinant protein purified from Escherichia coli strain Rosetta (DE3) has substantial wax synthase (WS) and lower diacylglycerol acyltransferase (DGAT) activity. Acyl-CoA substrate specificity, overview. TrWSD4 accepts four linear alcohols as substrates and the highest WS activity is observed for octadecanol (C18:0-OH), which is 2fold higher than the activity using decanol as substrate (C10:0-OH)
-
-
-
additional information
?
-
the recombinant protein purified from Escherichia coli strain Rosetta (DE3) has substantial wax synthase (WS) and lower diacylglycerol acyltransferase (DGAT) activity. Acyl-CoA substrate specificity, overview. TrWSD5 accepts four linear alcohols as substrates and the highest WS activity is observed for octadecanol (C18:0-OH), which is 2fold higher than the activity using decanol as substrate (C10:0-OH)
-
-
-
additional information
?
-
the recombinant protein purified from Escherichia coli strain Rosetta (DE3) has substantial wax synthase (WS) and lower diacylglycerol acyltransferase (DGAT) activity. Acyl-CoA substrate specificity, overview. TrWSD5 accepts four linear alcohols as substrates and the highest WS activity is observed for octadecanol (C18:0-OH), which is 2fold higher than the activity using decanol as substrate (C10:0-OH)
-
-
-
additional information
?
-
-
the recombinant protein purified from Escherichia coli strain Rosetta (DE3) has substantial wax synthase (WS) and lower diacylglycerol acyltransferase (DGAT) activity. Acyl-CoA substrate specificity, overview. TrWSD5 accepts four linear alcohols as substrates and the highest WS activity is observed for octadecanol (C18:0-OH), which is 2fold higher than the activity using decanol as substrate (C10:0-OH)
-
-
-
additional information
?
-
the recombinant protein purified from Escherichia coli strain Rosetta (DE3) has substantial wax synthase (WS) and lower diacylglycerol acyltransferase (DGAT) activity. Acyl-CoA substrate specificity, overview. TrWSD4 accepts four linear alcohols as substrates and the highest WS activity is observed for octadecanol (C18:0-OH), which is 2fold higher than the activity using decanol as substrate (C10:0-OH)
-
-
-
additional information
?
-
the recombinant protein purified from Escherichia coli strain Rosetta (DE3) has substantial wax synthase (WS) and lower diacylglycerol acyltransferase (DGAT) activity. Acyl-CoA substrate specificity, overview. TrWSD4 accepts four linear alcohols as substrates and the highest WS activity is observed for octadecanol (C18:0-OH), which is 2fold higher than the activity using decanol as substrate (C10:0-OH)
-
-
-
additional information
?
-
the recombinant protein purified from Escherichia coli strain Rosetta (DE3) has substantial wax synthase (WS) and lower diacylglycerol acyltransferase (DGAT) activity. Acyl-CoA substrate specificity, overview. TrWSD5 accepts four linear alcohols as substrates and the highest WS activity is observed for octadecanol (C18:0-OH), which is 2fold higher than the activity using decanol as substrate (C10:0-OH)
-
-
-
additional information
?
-
the recombinant protein purified from Escherichia coli strain Rosetta (DE3) has substantial wax synthase (WS) and lower diacylglycerol acyltransferase (DGAT) activity. Acyl-CoA substrate specificity, overview. TrWSD5 accepts four linear alcohols as substrates and the highest WS activity is observed for octadecanol (C18:0-OH), which is 2fold higher than the activity using decanol as substrate (C10:0-OH)
-
-
-
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