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inositol 1-phosphate phosphatase
inositol monophosphatase/fructose-1,6-bisphosphatase
inositol monophosphate phosphatase
inositol monophsphatase
-
-
inositol phosphohydrolase
-
-
-
-
inositol-1(or 4)-monophosphatase
inositol-1-phosphatase
-
-
-
-
L-myo-inositol 1-phosphate phosphatase
-
-
L-myo-inositol-1-phosphate phosphatase
-
-
-
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Lithium-sensitive myo-inositol monophosphatase A1
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-
-
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myo-inositol 1 (or 4) -monophosphatase
-
-
-
-
myo-inositol 1 (or 4) monophosphatase
-
-
myo-inositol 1-phosphatase
-
-
-
-
myo-inositol monophosphatase
myo-inositol monophosphatase 1
-
-
myo-inositol monophosphatase 2
-
-
Myo-inositol monophosphatase A2
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-
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myo-inositol monophosphatase-1
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myo-inositol monophosphate phosphatase
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myo-inositol-1(or 4)-phosphate phosphohydrolase
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myo-inositol-1-phosphatase
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myo-inositol-1-phosphatase/aryl-phosphatase
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exhibits also Zn-dependent aryl-phosphatase activity at acidic pH
myo-inositol-1-phosphate phosphohydrolase
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myo-inositol-phosphatase
-
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TM1415
exhibits dual specificity with both IMPase and fructose-1,6-bisphosphatase activities
AF2372

-
AF2372
exhibits NADP(H) phosphatase and fructose-1,6-bisphosphatase activities in addition to inositol monophosphatase activitity, but not 3'-phosphoadenosine 5'-phosphate phosphatase activity
All2917

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IMP

-
-
-
-
ImpA

-
IMPA1

-
-
IMPA2

-
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IMPase

-
-
-
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IMPase 1

-
IMPase A

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IMPase I

-
IMPase/FBPase

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-
inositol 1-phosphate phosphatase

-
-
-
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inositol 1-phosphate phosphatase
-
inositol monophosphatase

-
-
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inositol monophosphatase
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inositol monophosphatase
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inositol monophosphatase
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-
inositol monophosphatase
-
inositol monophosphatase
-
inositol monophosphatase
-
inositol monophosphatase
-
-
inositol monophosphatase
-
-
inositol monophosphatase
-
inositol monophosphatase
-
inositol monophosphatase
-
-
inositol monophosphatase
-
inositol monophosphatase
-
-
inositol monophosphatase
-
-
-
inositol monophosphatase
-
inositol monophosphatase
-
-
inositol monophosphatase
-
-
inositol monophosphatase/fructose-1,6-bisphosphatase

-
-
inositol monophosphatase/fructose-1,6-bisphosphatase
-
-
-
inositol monophosphate phosphatase

-
-
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-
inositol monophosphate phosphatase
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-
inositol monophosphate phosphatase
-
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inositol phosphatase

-
-
-
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inositol-1(or 4)-monophosphatase

-
-
-
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inositol-1(or 4)-monophosphatase
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-
MJ0109

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MJ0109
-
exhibits NADP(H) phosphatase and fructose-1,6-bisphosphatase activities in addition to the inositol monophosphatase activity, but not 3'-phosphoadenosine 5'-phosphate phosphatase activity
myo-inositol monophosphatase

-
myo-inositol monophosphatase
-
myo-inositol monophosphatase
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-
myo-inositol monophosphatase
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-
myo-inositol monophosphatase
-
SAS2203

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SuhB

-
additional information

-
archeal enzyme displays inositol monophosphatase as well as fructose 1,6-bisphosphatase activity
additional information
archeal enzyme displays inositol monophosphatase as well as fructose 1,6-bisphosphatase activity
additional information
archeal enzyme displays inositol monophosphatase as well as fructose 1,6-bisphosphatase activity
additional information
archeal enzyme displays inositol monophosphatase as well as fructose 1,6-bisphosphatase activity
-
additional information
-
archeal enzyme displays inositol monophosphatase as well as fructose 1,6-bisphosphatase activity
-
additional information
the enzyme belongs to the FIG superfamily of proteins
additional information
the enzyme belongs to the FIG superfamily of proteins
-
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(-)-(1R,2R,4R,6R)-2,4,6-trihydroxycyclohexyl cyclohexylammonium 1-hydroxyphosphonate + H2O
?
-
-
-
-
?
(-)-(1R,2R,4R,6R)-2,4,6-trihydroxycyclohexyl-1-hydroxyphosphonate cyclohexylammonium salt + H2O
?
-
-
-
-
?
1-L-chiro-inositol 3-phosphate
1-L-chiro-inositol + phosphate
-
-
-
-
?
2'-AMP + H2O
adenosine + phosphate
2'-CMP + H2O
cytidine + phosphate
2'-GMP + H2O
guanosine + phosphate
2'-phosphoadenosine 5'-phosphate + H2O
?
2'-UMP + H2O
uridine + phosphate
2,3-diphosphoglycerate + H2O
?
-
-
-
-
?
2-phosphoglycerate + H2O
?
2-phosphoglycerol + H2O
glycerol + phosphate
-
-
-
-
?
2-phosphoglycolate + H2O
?
-
-
-
-
?
3'-AMP + H2O
adenosine + phosphate
3'-CMP + H2O
cytidine + phosphate
-
-
-
-
?
3'-GMP + H2O
guanosine + phosphate
-
-
-
-
?
3'-UMP + H2O
uridine + phosphate
-
-
-
-
?
3,5-dideoxy-D-myo-inositol 1-phosphate + H2O
3,5-dideoxy-D-myo-inositol + phosphate
3,5-dideoxy-L-myo-inositol 1-phosphate + H2O
3,5-dideoxy-L-myo-inositol + phosphate
3-deoxy-D-myo-inositol 1-phosphate + H2O
3-deoxy-D-myo-inositol + phosphate
3-deoxy-L-myo-inositol 1-phosphate + H2O
3-deoxy-L-myo-inositol + phosphate
3-phosphoglycerate + H2O
?
-
-
-
-
?
4-nitrophenyl phosphate + H2O
4-nitrophenol + phosphate
5'-CMP + H2O
cytidine + phosphate
-
-
-
-
?
5'-dAMP + H2O
adenosine + phosphate
-
-
-
-
?
5'-GMP + H2O
guanosine + phosphate
-
-
-
-
?
5'-UMP + H2O
uridine + phosphate
-
-
-
-
?
6-phosphogluconate + H2O
?
-
-
-
-
?
alpha-D-galactose 1-phosphate + H2O
alpha-D-galactose + phosphate
-
-
-
-
?
alpha-D-glucose 1-phosphate
alpha-D-glucose + phosphate
IMPA1 shows intermediate activity towards alpha-D-glucose 1-phosphate, whereas IMPA2 shows significantly lower affinity
-
-
?
alpha-D-glucose 1-phosphate + H2O
alpha-D-glucose + phosphate
ATP + H2O
ADP + phosphate
-
-
-
-
?
D-alpha-galactose 1-phosphate + H2O
?
-
-
-
-
?
D-alpha-glucose 1-phosphate + H2O
?
-
-
-
-
?
D-beta glucose 1-phosphate + H2O
?
-
-
-
-
?
D-erythrose 4-phosphate + H2O
D-erythrose + phosphate
-
-
-
-
?
D-fructose 1,6-bisphosphate + H2O
D-fructose 6-phosphate + phosphate
D-fructose 1-phosphate + H2O
D-fructose + phosphate
D-fructose 2,6-bisphosphate + H2O
D-fructose 6-phosphate + phosphate
D-fructose 6-phosphate + H2O
?
-
-
-
-
?
D-fructose 6-phosphate + H2O
D-fructose + phosphate
-
-
-
-
?
D-galactose 1-phosphate + H2O
D-galactose + phosphate
105% of the activity with D-myo-inositol 1-phosphate
-
-
?
D-glucitol-6-phosphate + H2O
D-glucitol + phosphate
-
hydrolyzed very slowly
-
-
?
D-glucose 1-phosphate + H2O
D-glucose + phosphate
D-glucose 6-phosphate + H2O
?
D-glucose 6-phosphate + H2O
D-glucose + phosphate
-
-
-
-
?
D-glucose-6-phosphate + H2O
D-glucose + phosphate
-
-
-
-
?
D-inositol 1-phosphate + H2O
D-inositol + phosphate
-
-
-
-
?
D-mannitol-6-phosphate + H2O
D-mannitol + phosphate
-
hydrolyzed very slowly
-
-
?
D-mannose 6-phosphate + H2O
?
-
-
-
-
?
D-myo-inositol 1,2,3,4,5,6-hexakisphosphate + H2O
D-myo-inositol 1,2,3,4,5-pentakisphosphate + phosphate
-
-
-
-
?
D-myo-inositol 1,4-bisphosphate + H2O
?
D-myo-inositol 1-phosphate + H2O
D-myo-inositol + phosphate
D-myo-inositol 2-phosphate + H2O
D-myo-inositol + phosphate
D-myo-inositol 3-phosphate + H2O
D-myo-inositol + phosphate
D-ribose 5-phosphate + H2O
?
-
-
-
-
?
D-ribose 5-phosphate + H2O
D-ribose + phosphate
-
-
-
-
?
D-xylose 5-phosphate + H2O
D-xylose + phosphate
-
-
-
-
?
diphosphate + H2O
2 phosphate
-
-
-
-
?
DL-myo-inositol 1-phosphate + H2O
DL-myo-inositol + phosphate
fructose 1-phosphate + H2O
?
-
-
-
-
?
fructose 6-phosphate + H2O
?
-
-
-
-
?
glucitol 6-phosphate + H2O
glucitol + phosphate
-
-
-
?
glucose 1-phosphate + H2O
?
glycerol 2-phosphate + H2O
glycerol + phosphate
inosine 5'-phosphate + H2O
?
-
-
-
-
?
inositol 1,3-thiophosphate + H2O
?
-
-
-
-
?
inositol 1-phosphate + H2O
inositol + phosphate
inositol 1-phosphate + H2O
myo-inositol + phosphate
inositol 2-phosphate + H2O
?
inositol 4-phosphate + H2O
myo-inositol + phosphate
-
the inositol ring docks to the enzyme by forming four hydrogen bonds: the 2-OH group with Asp104, the 3-OH with Asp231, the 5-OH group with Thr106, and the 6-OH with the carbonyl group of main chain of Gly205
-
-
?
L-chiro-inositol-3-phosphate + H2O
?
L-glycerol 1-phosphate + H2O
glycerol + phosphate
L-histidinol phosphate + H2O
L-histidinol + phosphate
-
-
-
?
L-myo-inositol 1-phosphate + H2O
L-myo-inositol + phosphate
mannitol 1-phosphate + H2O
mannitol + phosphate
-
-
-
?
myo-inositol 1,3-thiophosphate + H2O
?
-
reaction 3times slower than reaction with inositol 1-phosphate
-
?
myo-inositol 1,4-bisphosphate + H2O
?
-
-
-
?
myo-inositol 1-phosphate + H2O
myo-inositol + phosphate
myo-inositol 2-phosphate + H2O
myo-inositol + phosphate
myo-inositol 3-phosphate + H2O
myo-inositol + phosphate
myo-inositol 4-phosphate + H2O
myo-inositol + phosphate
myo-inositol 5-phosphate + H2O
myo-inositol + phosphate
myo-inositol 6-phosphate + H2O
myo-inositol + phosphate
myo-inositol phosphate + H2O
myo-inositol + phosphate
p-nitrophenyl phosphate + H2O
p-nitrophenol + phosphate
phosphatidylinositol 4,5-bisphosphate + H2O
?
-
-
-
-
?
phosphatidylinositol 4-phosphate + H2O
phosphatidylinositol + phosphate
-
-
-
?
propan-1-ol 2-phosphate + H2O
1-propanol + phosphate
-
-
-
-
?
purine nucleotides + H2O
?
-
-
-
-
?
pyrimidine ribonucleotides + H2O
?
-
-
-
-
?
scyllo-inositol 1-phosphate + H2O
scyllo-inositol + phosphate
IMPA1 shows strong activity towards scyllo-inositol 1-phosphate, whereas IMPA2 shows almost no affinity
-
-
?
additional information
?
-
2'-AMP + H2O

adenosine + phosphate
-
-
-
?
2'-AMP + H2O
adenosine + phosphate
-
-
-
-
?
2'-AMP + H2O
adenosine + phosphate
-
-
-
?
2'-AMP + H2O
adenosine + phosphate
-
-
-
-
?
2'-AMP + H2O
adenosine + phosphate
-
-
-
-
?
2'-AMP + H2O
adenosine + phosphate
-
-
-
-
?
2'-AMP + H2O
adenosine + phosphate
600% of the rate with inositol 1-phosphate
-
?
2'-AMP + H2O
adenosine + phosphate
600% of the rate with inositol 1-phosphate
-
?
2'-AMP + H2O
adenosine + phosphate
600% of the rate with inositol 1-phosphate
-
?
2'-AMP + H2O
adenosine + phosphate
-
-
-
?
2'-AMP + H2O
adenosine + phosphate
-
-
-
-
?
2'-AMP + H2O
adenosine + phosphate
-
18% of the rate with inositol 1-phosphate
-
?
2'-AMP + H2O
adenosine + phosphate
-
-
-
-
?
2'-CMP + H2O

cytidine + phosphate
-
-
-
-
?
2'-CMP + H2O
cytidine + phosphate
-
-
-
-
?
2'-GMP + H2O

guanosine + phosphate
-
-
-
-
?
2'-GMP + H2O
guanosine + phosphate
-
-
-
-
?
2'-phosphoadenosine 5'-phosphate + H2O

?
-
-
-
?
2'-phosphoadenosine 5'-phosphate + H2O
?
-
-
-
-
?
2'-UMP + H2O

uridine + phosphate
-
-
-
-
?
2'-UMP + H2O
uridine + phosphate
-
-
-
-
?
2-phosphoglycerate + H2O

?
-
-
-
-
?
2-phosphoglycerate + H2O
?
-
-
-
-
?
3'-AMP + H2O

adenosine + phosphate
-
-
-
-
?
3'-AMP + H2O
adenosine + phosphate
-
-
-
-
?
3'-AMP + H2O
adenosine + phosphate
-
-
-
-
?
3,5-dideoxy-D-myo-inositol 1-phosphate + H2O

3,5-dideoxy-D-myo-inositol + phosphate
-
-
-
-
?
3,5-dideoxy-D-myo-inositol 1-phosphate + H2O
3,5-dideoxy-D-myo-inositol + phosphate
-
-
-
?
3,5-dideoxy-D-myo-inositol 1-phosphate + H2O
3,5-dideoxy-D-myo-inositol + phosphate
-
-
-
-
?
3,5-dideoxy-L-myo-inositol 1-phosphate + H2O

3,5-dideoxy-L-myo-inositol + phosphate
-
-
-
-
?
3,5-dideoxy-L-myo-inositol 1-phosphate + H2O
3,5-dideoxy-L-myo-inositol + phosphate
-
-
-
?
3,5-dideoxy-L-myo-inositol 1-phosphate + H2O
3,5-dideoxy-L-myo-inositol + phosphate
-
-
-
-
?
3-deoxy-D-myo-inositol 1-phosphate + H2O

3-deoxy-D-myo-inositol + phosphate
-
-
-
-
?
3-deoxy-D-myo-inositol 1-phosphate + H2O
3-deoxy-D-myo-inositol + phosphate
-
-
-
-
?
3-deoxy-L-myo-inositol 1-phosphate + H2O

3-deoxy-L-myo-inositol + phosphate
-
-
-
-
?
3-deoxy-L-myo-inositol 1-phosphate + H2O
3-deoxy-L-myo-inositol + phosphate
-
-
-
-
?
4-nitrophenyl phosphate + H2O

4-nitrophenol + phosphate
-
-
-
?
4-nitrophenyl phosphate + H2O
4-nitrophenol + phosphate
-
very effective substrate
-
?
4-nitrophenyl phosphate + H2O
4-nitrophenol + phosphate
-
very effective substrate
-
?
4-nitrophenyl phosphate + H2O
4-nitrophenol + phosphate
-
-
-
?
4-nitrophenyl phosphate + H2O
4-nitrophenol + phosphate
-
-
-
-
?
4-nitrophenyl phosphate + H2O
4-nitrophenol + phosphate
-
-
-
-
?
4-nitrophenyl phosphate + H2O
4-nitrophenol + phosphate
-
high rate of hydrolysis
-
-
?
4-nitrophenyl phosphate + H2O
4-nitrophenol + phosphate
very effective substrate
-
?
4-nitrophenyl phosphate + H2O
4-nitrophenol + phosphate
very effective substrate
-
?
4-nitrophenyl phosphate + H2O
4-nitrophenol + phosphate
very effective substrate
-
?
4-nitrophenyl phosphate + H2O
4-nitrophenol + phosphate
-
-
-
-
?
4-nitrophenyl phosphate + H2O
4-nitrophenol + phosphate
-
-
-
-
?
4-nitrophenyl phosphate + H2O
4-nitrophenol + phosphate
-
very effective substrate
-
?
4-nitrophenyl phosphate + H2O
4-nitrophenol + phosphate
-
very effective substrate
-
?
alpha-D-glucose 1-phosphate + H2O

alpha-D-glucose + phosphate
-
-
-
?
alpha-D-glucose 1-phosphate + H2O
alpha-D-glucose + phosphate
-
-
-
?
alpha-D-glucose 1-phosphate + H2O
alpha-D-glucose + phosphate
-
-
?
alpha-D-glucose 1-phosphate + H2O
alpha-D-glucose + phosphate
-