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Literature summary for 3.1.3.25 extracted from

  • Kraft, L.; Roe, S.M.; Gill, R.; Atack, J.R.
    Co-crystallization of human inositol monophosphatase with the lithium mimetic L-690,330 (2018), Acta Crystallogr. Sect. D, 74, 973-978 .
    View publication on PubMed

Crystallization (Commentary)

Crystallization (Comment) Organism
structure in complex with inhibitor L-690330 and manganese ions, at 1.39 A resolution. Presence of L-690330 significantly increases the thermal stability of IMPase Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
L-690330 bisphosphonate substrate-based inhibitor Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens P29218
-
-

Synonyms

Synonyms Comment Organism
IMPA1
-
Homo sapiens