Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Ca2+ | strong competitive against Mg2+ | Rattus norvegicus | |
Cu2+ | - |
Rattus norvegicus | |
Li+ | inhibits 50% of activity at 1 mM, uncompetitive inhibitor | Rattus norvegicus | |
Mn2+ | strong competitive against Mg2+ | Rattus norvegicus | |
NaF | inhibits by 60% and 100% at 1 mM and 5 mM respectively | Rattus norvegicus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.12 | - |
DL-myo-inositol 1-phosphate | - |
Rattus norvegicus | |
0.19 | - |
2'-AMP | - |
Rattus norvegicus | |
0.77 | - |
Glycerol 2-phosphate | - |
Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytoplasm | - |
Rattus norvegicus | 5737 | - |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Co2+ | 40% stimulation | Rattus norvegicus | |
Co2+ | less effective than Mg2+, cannot substitute for Mg2+ | Rattus norvegicus | |
Fe2+ | less effective than Mg2+, cannot substitute for Mg2+ | Rattus norvegicus | |
Mg2+ | stimulates | Rattus norvegicus | |
Mn2+ | stimulates slightly | Rattus norvegicus | |
Zn2+ | 40% stimulation | Rattus norvegicus |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
29000 | - |
2 * 29000, SDS-PAGE | Rattus norvegicus |
55000 | - |
gel filtration | Rattus norvegicus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
myo-inositol 1-phosphate + H2O | Rattus norvegicus | - |
myo-inositol + phosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
6000 and 2563fold | Rattus norvegicus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | - |
Rattus norvegicus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.85 | - |
- |
Rattus norvegicus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
2'-AMP + H2O | - |
Rattus norvegicus | adenosine + phosphate | - |
? | |
2'-GMP + H2O | - |
Rattus norvegicus | guanosine + phosphate | - |
? | |
DL-myo-inositol 1-phosphate + H2O | - |
Rattus norvegicus | DL-myo-inositol + phosphate | - |
? | |
glycerol 2-phosphate + H2O | - |
Rattus norvegicus | glycerol + phosphate | - |
? | |
L-glycerol 1-phosphate + H2O | - |
Rattus norvegicus | glycerol + phosphate | - |
? | |
additional information | - |
Rattus norvegicus | ? | - |
? | |
myo-inositol 1-phosphate + H2O | - |
Rattus norvegicus | myo-inositol + phosphate | - |
? |
Subunits | Comment | Organism |
---|---|---|
dimer | 2 * 29000, SDS-PAGE | Rattus norvegicus |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
- |
Rattus norvegicus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.4 | - |
for L-myo-inositol-1-phosphate | Rattus norvegicus |
8 | - |
for 2-AMP, beta-glycerophosphate | Rattus norvegicus |