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Literature summary for 3.1.3.25 extracted from

  • Stieglitz, K.A.; Roberts, M.F.; Li, W.; Stec, B.
    Crystal structure of the tetrameric inositol 1-phosphate phosphatase (TM1415) from the hyperthermophile, Thermotoga maritima (2007), FEBS J., 274, 2461-2469.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli Thermotoga maritima

Crystallization (Commentary)

Crystallization (Comment) Organism
standing drop vapour diffusion method with 15% (w /v) PEG 4000, 15% (v /v) PEG 400, 0.2 M MgSO4, and 50 mM (NH4)2SO4, in 50 mM cacodylate buffer, pH 8 Thermotoga maritima

Organism

Organism UniProt Comment Textmining
Thermotoga maritima O33832
-
-

Purification (Commentary)

Purification (Comment) Organism
Sepharose Q FF column chromatography Thermotoga maritima

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
glycerol 2-phosphate + H2O
-
Thermotoga maritima glycerol + phosphate
-
?
L-myo-inositol 1-phosphate + H2O
-
Thermotoga maritima L-myo-inositol + phosphate
-
?

Subunits

Subunits Comment Organism
tetramer x-ray crystallography Thermotoga maritima

Synonyms

Synonyms Comment Organism
IMPase
-
Thermotoga maritima
inositol 1-phosphate phosphatase
-
Thermotoga maritima
TM1415 exhibits dual specificity with both IMPase and fructose-1,6-bisphosphatase activities Thermotoga maritima