EC Number |
Recommended Name |
Source Tissue |
Reference |
---|
6.3.3.2 | 5-formyltetrahydrofolate cyclo-ligase |
CHO cell |
CHO, ovary cell line and its methotrexate resistant subline |
1327 |
5.1.3.7 | UDP-N-acetylglucosamine 4-epimerase |
CHO cell |
ldlD cells are deficient in UDP-N-acetylglucosamine 4-epimerase |
2410 |
3.1.3.35 | thymidylate 5'-phosphatase |
CHO cell |
- |
81087 |
7.2.2.9 | P-type Cu2+ transporter |
CHO cell |
copper-resistant CHO cells which overexpress the enzyme |
246912 |
1.1.1.205 | IMP dehydrogenase |
CHO cell |
- |
347910 |
1.17.4.1 | ribonucleoside-diphosphate reductase |
CHO cell |
- |
437919 |
2.4.1.221 | peptide-O-fucosyltransferase |
CHO cell |
- |
441440, 441442, 703986 |
2.4.1.68 | glycoprotein 6-alpha-L-fucosyltransferase |
CHO cell |
- |
441440, 441442, 702784 |
2.3.1.26 | sterol O-acyltransferase |
CHO cell |
CHO cells, cultured cells |
486677, 486690 |
2.3.1.26 | sterol O-acyltransferase |
CHO cell |
- |
486693, 486703, 674216 |
2.3.1.57 | diamine N-acetyltransferase |
CHO cell |
- |
487265, 662129 |
2.4.1.144 | beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase |
CHO cell |
LEC10 ovary cell line |
488370 |
2.4.1.144 | beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase |
CHO cell |
ricin resistant mutant |
488370 |
2.4.1.101 | alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase |
CHO cell |
wild-type and mutant F6 and F8 |
488371 |
2.4.1.101 | alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase |
CHO cell |
wild-type, Lec1 cells are deficient in enzyme activity, mutant Lec1A cells show weak enzyme activity, 2% compared to wild-type, and produce complex N-glycans |
488380 |
2.4.1.80 | ceramide glucosyltransferase |
CHO cell |
strain K1, and GM3-mutant strain Z65 |
489424 |
2.4.1.198 | phosphatidylinositol N-acetylglucosaminyltransferase |
CHO cell |
CHO-K1 cell lines G9PLAP and mutant G9PLAP.85 |
638133 |
2.4.1.144 | beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase |
CHO cell |
- |
638214 |
2.4.1.102 | beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase |
CHO cell |
- |
638279 |
2.4.1.149 | N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase |
CHO cell |
Pro-5 and Lec2 CHO cells |
638584 |
2.7.1.20 | adenosine kinase |
CHO cell |
- |
641111, 660724, 663319 |
2.7.7.19 | polynucleotide adenylyltransferase |
CHO cell |
- |
642938 |
2.7.8.5 | CDP-diacylglycerol-glycerol-3-phosphate 1-phosphatidyltransferase |
CHO cell |
- |
644299 |
2.7.8.1 | ethanolaminephosphotransferase |
CHO cell |
- |
644415 |
2.7.7.30 | fucose-1-phosphate guanylyltransferase |
CHO cell |
- |
645224 |
2.7.7.43 | N-acylneuraminate cytidylyltransferase |
CHO cell |
- |
645275 |
2.7.8.15 | UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase |
CHO cell |
- |
645359, 645360, 645364, 645366, 645367, 703322 |
2.8.2.8 | [heparan sulfate]-glucosamine N-sulfotransferase |
CHO cell |
- |
645941 |
3.1.2.2 | palmitoyl-CoA hydrolase |
CHO cell |
- |
646175 |
3.1.2.20 | acyl-CoA hydrolase |
CHO cell |
- |
646175 |
1.3.5.1 | succinate dehydrogenase |
CHO cell |
- |
654199 |
1.1.1.8 | glycerol-3-phosphate dehydrogenase (NAD+) |
CHO cell |
- |
654824 |
3.2.1.18 | exo-alpha-sialidase |
CHO cell |
- |
655170, 655171 |
1.7.3.3 | factor-independent urate hydroxylase |
CHO cell |
wild-type and PEX5-defective CHO cell lines each stable producing the enzyme |
657736 |
2.3.1.50 | serine C-palmitoyltransferase |
CHO cell |
- |
658109, 659868 |
1.14.18.2 | CMP-N-acetylneuraminate monooxygenase |
CHO cell |
generation of a stable CHO cell line with significantly reduced levels of CMP-Neu5Ac hydroxylase activity and reduced amounts of N-glycolylneuraminic acid, using a rational antisense RNA strategy |
658179 |
2.4.1.83 | dolichyl-phosphate beta-D-mannosyltransferase |
CHO cell |
- |
658867 |
2.4.1.135 | galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase |
CHO cell |
- |
659141, 659435 |
2.7.8.29 | L-serine-phosphatidylethanolamine phosphatidyltransferase |
CHO cell |
- |
661228, 717758, 717761 |
2.7.11.11 | cAMP-dependent protein kinase |
CHO cell |
- |
661759 |
3.6.5.2 | small monomeric GTPase |
CHO cell |
- |
665471, 719932 |
3.4.22.61 | caspase-8 |
CHO cell |
- |
666402 |
2.7.8.27 | sphingomyelin synthase |
CHO cell |
- |
667767 |
3.4.24.86 | ADAM 17 endopeptidase |
CHO cell |
mutated sublines M1 and M2. M1 contains only one expressible TACE allele encoding an M435I point mutation in the catalytic center of the protease, and M2 cells produce two TACE variants with distinct point mutations in the catalytic domain (C22Y) and the cysteine-rich/disintegrin domain (C600Y) |
669237 |
3.4.24.86 | ADAM 17 endopeptidase |
CHO cell |
- |
669269 |
1.14.13.39 | nitric-oxide synthase (NADPH) |
CHO cell |
- |
675520 |
2.4.1.38 | beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase |
CHO cell |
- |
675791 |
2.4.1.90 | N-acetyllactosamine synthase |
CHO cell |
- |
675952 |
3.1.3.36 | phosphoinositide 5-phosphatase |
CHO cell |
- |
677869 |
4.6.1.1 | adenylate cyclase |
CHO cell |
expresses all nine adenylate cyclase isoforms |
678381 |
4.6.1.1 | adenylate cyclase |
CHO cell |
- |
679659, 695074 |
2.4.1.83 | dolichyl-phosphate beta-D-mannosyltransferase |
CHO cell |
CHO 2.38 cel |
680743 |
3.1.4.3 | phospholipase C |
CHO cell |
stably expressing human imidazoline receptor antisera-selected protein IRAS |
681028 |
3.4.21.75 | Furin |
CHO cell |
- |
681690, 700401 |
3.4.22.61 | caspase-8 |
CHO cell |
inhibition of caspase-8 enhances the viability of the CHO cells in both batch and fed-batch suspension cultures. Caspase-8 is possible involved in the apoptotic cell death in batch and fed-batch cultures of CHO cells |
681759 |
3.4.22.62 | caspase-9 |
CHO cell |
inhibition of caspase-9 enhances the viability of the CHO cells in both batch and fed-batch suspension cultures. Caspase-9 is possible involved in the apoptotic cell death in batch and fed-batch cultures of CHO cells |
681759 |
3.4.23.46 | memapsin 2 |
CHO cell |
inhibitor drugs tested |
683381 |
2.4.1.141 | N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase |
CHO cell |
- |
685092 |
3.6.5.5 | dynamin GTPase |
CHO cell |
- |
686581 |
2.7.1.138 | ceramide kinase |
CHO cell |
- |
690700 |
3.2.1.166 | heparanase |
CHO cell |
- |
690796, 692520 |
3.1.3.4 | phosphatidate phosphatase |
CHO cell |
- |
690815 |
5.6.2.2 | DNA topoisomerase (ATP-hydrolysing) |
CHO cell |
- |
691628 |
6.1.1.4 | leucine-tRNA ligase |
CHO cell |
- |
693164 |
3.2.1.106 | mannosyl-oligosaccharide glucosidase |
CHO cell |
- |
694198 |
3.1.22.1 | deoxyribonuclease II |
CHO cell |
- |
696131 |
3.4.17.12 | carboxypeptidase M |
CHO cell |
- |
696532 |
3.4.22.56 | caspase-3 |
CHO cell |
- |
696881 |
3.4.22.60 | caspase-7 |
CHO cell |
- |
696881 |
3.5.1.23 | ceramidase |
CHO cell |
- |
697229 |
2.4.2.8 | hypoxanthine phosphoribosyltransferase |
CHO cell |
- |
701888 |
2.5.1.26 | alkylglycerone-phosphate synthase |
CHO cell |
- |
702411 |
2.4.1.221 | peptide-O-fucosyltransferase |
CHO cell |
fucosylation-deficient Lec13 chinese hamster ovary cells have wild-type levels of Pofut1 and cell surface Notch receptors |
704420 |
3.4.21.112 | site-1 protease |
CHO cell |
- |
710345 |
3.4.23.46 | memapsin 2 |
CHO cell |
- |
711091, 711303, 734729 |
3.4.23.5 | cathepsin D |
CHO cell |
- |
711533, 753060 |
7.6.2.1 | P-type phospholipid transporter |
CHO cell |
- |
720146 |
2.4.3.1 | beta-galactoside alpha-(2,6)-sialyltransferase |
CHO cell |
- |
721384 |
2.7.7.15 | choline-phosphate cytidylyltransferase |
CHO cell |
- |
721712 |
2.4.2.31 | NAD+-protein-arginine ADP-ribosyltransferase |
CHO cell |
- |
722180 |
2.7.1.67 | 1-phosphatidylinositol 4-kinase |
CHO cell |
- |
723136 |
1.3.1.72 | DELTA24-sterol reductase |
CHO cell |
- |
724442 |
4.1.1.21 | phosphoribosylaminoimidazole carboxylase |
CHO cell |
accumulates 5-aminoimidazole ribotide |
728311 |
3.4.11.3 | cystinyl aminopeptidase |
CHO cell |
- |
731661 |
7.6.2.2 | ABC-type xenobiotic transporter |
CHO cell |
- |
733268 |
3.4.24.85 | S2P endopeptidase |
CHO cell |
- |
735261 |
2.4.1.155 | alpha-1,6-mannosyl-glycoprotein 6-beta-N-acetylglucosaminyltransferase |
CHO cell |
- |
736218 |
2.6.1.2 | alanine transaminase |
CHO cell |
- |
737896 |
1.14.13.9 | kynurenine 3-monooxygenase |
CHO cell |
- |
742349 |
6.1.1.20 | phenylalanine-tRNA ligase |
CHO cell |
- |
744547 |
6.3.2.17 | tetrahydrofolate synthase |
CHO cell |
- |
744775 |
6.1.1.1 | tyrosine-tRNA ligase |
CHO cell |
- |
745300 |
3.4.16.6 | carboxypeptidase D |
CHO cell |
- |
753046 |
3.4.17.22 | metallocarboxypeptidase D |
CHO cell |
- |
753046 |
3.4.22.15 | cathepsin L |
CHO cell |
- |
753061 |