Information on EC 3.5.1.98 - histone deacetylase

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The expected taxonomic range for this enzyme is: Bacteria, Eukaryota

EC NUMBER
COMMENTARY hide
3.5.1.98
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RECOMMENDED NAME
GeneOntology No.
histone deacetylase
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
hydrolysis of an N6-acetyl-lysine residue of a histone to yield a deacetylated histone
show the reaction diagram
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SYSTEMATIC NAME
IUBMB Comments
histone amidohydrolase
A class of enzymes that remove acetyl groups from N6-acetyl-lysine residues on a histone. The reaction of this enzyme is opposite to that of EC 2.3.1.48, histone acetyltransferase. Histone deacetylases (HDACs) can be organized into three classes, HDAC1, HDAC2 and HDAC3, depending on sequence similarity and domain organization. Histone acetylation plays an important role in regulation of gene expression. In eukaryotes, HDACs play a key role in the regulation of transcription and cell proliferation [4]. May be identical to EC 3.5.1.17, acyl-lysine deacylase.
CAS REGISTRY NUMBER
COMMENTARY hide
9076-57-7
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ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
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Automatic Mining of ENzyme DAta
i.e. Bordetella sp. strain FB188
SwissProt
Manually annotated by BRENDA team
Alcaligenes sp. DSM 11172
i.e. Bordetella sp. strain FB188
SwissProt
Manually annotated by BRENDA team
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
bat
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
Candida albicans ATCC 90028
gene HOS2
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Manually annotated by BRENDA team
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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1119669 A+, 1140386 A+, 1162345 A+, 1162353 A+, 1229541 A+, 1229568 A+, 1229650 A+, 1229675 A+, 1229686 A+, 1229687 A+, 1229699 A+, 1229768 A+, 1229772 A+, 1229778 A+, 1229789 A+, 1229805 A+, 1229809 A+, 1229834 A+, 1229846 A+, 1229848 A+, 1229852 A+, 1229885 A+, 1229893 A+, 1229897 A+, 1229935 A+, 1229937 A+, 1229940 A+, 1229945 A+, 1229965 A+, 1229966 A+, 1229981 A+, 1229992 A+, 1229995 A+, 1229996 A+, 1230044 A+, 1230049 A+, 1230058 A+, 1230098 A+, 1230106 A+, 1230117 A+, 1230138 A+, 1230150 A+, 1230153 A+, 1230177 A+, 1230179 A+, 1230186 A+, 1230228 A+, 1230236 A+, 1230240 A+, 1230265 A+, 1230276 A+, 1230278 A+, 1230281 A+, 1230290 A+, 1230292 A+, 1230296 A+, 1230308 A+, 1230315 A+, 1230321 A+, 1230323 A+, 1230358 A+, 1230367 A+, 1230396 A+, 1230399 A+, 1230427 A+, 1230450 A+, 1230463 A+, 1230468 A+, 1230470 A+, 1230502 A+, 1230518 A+, 1230539 A+, 1230590 A+, 1230594 A+, 1230599 A+, 1230612 A+, 1230628 A+, 1230639 A+, 1230642 A+, 1230662 A+, 1230674 A+, 1230683 A+, 1230721 A+, 1230722 A+, 1247082 A+, 1327829 A+, 1366687 A+, 1506223 A+, 1520169 A+, 1540861 A+, 1596766 A+, 1597859 A+, 1614439 A+, 1761222 A+, 1878553 A+, 1878733 A+, 1888199 A+, 1888284 A+, 1933670 A+, 1936636 A+, 1943823 A+, 1973518 A+, 1985287 A+, 1986300 A+, 1994755 A+, 2012658 A+, 2018200 A+, 2040778 A+, 2080504 A+, 2080595 A+, 2080609 A+, 2080624 A+, 2080629 A+, 2080703 A+, 2080766 A+, 2080777 A+, 2080780 A+, 2080785 A+, 2080795 A+, 2080798 A+, 2080907 A+, 2080918 A+, 2080920 A+, 2080946 A+, 2080961 A+, 2080974 A+, 2080975 A+, 2080991 A+, 2081020 A+, 2081022 A+, 2081043 A+, 2081072 A+, 2081129 A+, 2081136 A+, 2081146 A+, 2081158 A+, 2081173 A+, 2081178 A+, 2081203 A+, 2081214 A+, 2081217 A+, 2081255 A+, 2081273 A+, 2081274 A+, 2081302 A+, 2081327 A+, 2081335 A+, 2081382 A+, 2081384 A+, 2081401 A+, 2081441 A+, 2081465 A+, 2081545 A+, 2081575 A+, 2081578 A+, 2081609 A+, 2081634 A+, 2081668 A+, 2081720 A+, 2081741 A+, 2081746 A+, 2108407 A+, 2112836 A+, 2117707 A+, 2163390 A+, 2171320 A+, 2205634 A+, 2226105 A+, 2226739 A+, 2226899 A+, 2296170 A+, 2296199 A+, 2299889 A+, 2309048 A+, 2326248 A+, 2371072 A+, 2380687 A+, 2393650 A+, 2393758 A+, 2393854 A+, 2393919 A+, 2393990 A+, 2394019 A+, 2394035 A+, 2394062 A+, 2394076 A+, 2394139 A+, 2394157 A+, 2394312 A+, 2394315 A+, 2394372 A+, 2394448 A+, 2394452 A+, 2394540 A+, 2394561 A+, 2394597 A+, 2394638 A+, 2394669 A+, 2394671 A+, 2394673 A+, 2394705 A+, 2394715 A+, 2394734 A+, 2394745 A+, 2394753 A+, 2394773 A+, 2394779 A+, 2394818 A+, 2394838 A+, 2394846 A+, 2394868 A+, 2394875 A+, 2394900 A+, 2394906 A+, 2394909 A+, 2394961 A+, 2394963 A+, 2394964 A+, 2394976 A+, 2394994 A+, 2395009 A+, 2395011 A+, 2395028 A+, 2395055 A+, 2395115 A+, 2395117 A+, 2395130 A+, 2395156 A+, 2395161 A+, 2395169 A+, 2395179 A+, 2395187 A+, 2395205 A+, 2395206 A+, 2395216 A+, 2395223 A+, 2395227 A+, 2395236 A+, 2395258 A+, 2395268 A+, 2395282 A+, 2395290 A+, 2395295 A+, 2395301 A+, 2395302 A+, 2395309 A+, 2395324 A+, 2395330 A+, 2395346 A+, 2401580 A+, 2406916 A+, 2407584 A+, 2407730 A+, 2470844 A+, 2490062 A+, 2662401 A+, 2664107 A+, 2686124 A+, 2700770 A+, 2729049 A+, 2748898 A+, 2749434 A+, 2786830 A+, 2793964 A+, 2876578 A+, 2901313 A+, 2901466 A+, 2901544 A+, 2901580 A+, 2911880 A+, 2912417 A+, 2912925 A+, 2919864 A+, 2951728 A+, 2956526 A+, 2964084 A+, 2964679 A+, 2964768 A+, 3008745 A+, 3013414 A+, 3027464 A+, 3029834 A+, 3035198 A+, 3038052 A+, 3090612 A+, 3101786 A+, 3109414 A+, 3109471 A+, 3109527 A+, 3109565 A+, 3109768 A+, 3109938 A+, 3109971 A+, 3110006 A+, 3110063 A+, 3110114 A+, 3110167 A+, 3110193 A+, 3110245 A+, 3110260 A+, 3110262 A+, 3110263 A+, 3110269 A+, 3110298 A+, 3110305 A+, 3110350 A+, 3110353 A+, 3110362 A+, 3110375 A+, 3110395 A+, 3110432 A+, 3110450 A+, 3110461 A+, 3110464 A+, 3110467 A+, 3110474 A+, 3110523 A+, 3110546 A+, 3110560 A+, 3110575 A+, 3110611 A+, 3110645 A+, 3110675 A+, 3110789 A+, 3110790 A+, 3110851 A+, 3110892 A+, 3110899 A+, 3110934 A+, 697607 A+, 713115 A+, 731541 A+, 735001 A+, 736872 A+, 778999 A+, 861418 A+, 870101 A+, 906703 A+, 1032510 A++, 1133469 A++, 1229761 A++, 1229910 A++, 1230031 A++, 1230071 A++, 1230254 A++, 1230345 A++, 1230414 A++, 1230566 A++, 1230582 A++, 1230583 A++, 1585170 A++, 1927904 A++, 2080913 A++, 2081604 A++, 2347412 A++, 2347435 A++, 2394057 A++, 2394092 A++, 2394210 A++, 2394212 A++, 2394228 A++, 2394278 A++, 2394335 A++, 2394352 A++, 2394496 A++, 2394502 A++, 2394546 A++, 2394547 A++, 2394558 A++, 2394615 A++, 2394689 A++, 2394693 A++, 2394694 A++, 2394707 A++, 2394790 A++, 2394799 A++, 2394801 A++, 2394808 A++, 2394812 A++, 2394879 A++, 2394919 A++, 2394929 A++, 2394938 A++, 2394951 A++, 2394952 A++, 2394958 A++, 2394962 A++, 2395092 A++, 2395106 A++, 2395114 A++, 2395121 A++, 2395122 A++, 2395136 A++, 2395253 A++, 2569076 A++, 2956275 A++, 3109795 A++, 3109849 A++, 3110156 A++, 3110514 A++, 3110722 A++, 697354 A++, 1094502 A++, 1230200 A++, 1230304 A++, 1230425 A++, 1230494 A++, 1230591 A++, 1230608 A++, 1230610 A++, 1230661 A++, 1869671 A++, 1879719 A++, 1879720 A++, 2080876 A++, 2080910 A++, 2080914 A++, 2080951 A++, 2081216 A++, 2081227 A++, 2081235 A++, 2081353 A++, 2081451 A++, 2081456 A++, 2081582 A++, 2081586 A++, 2119053 A++, 2126308 A++, 2127016 A++, 2137142 A++, 2185123 A++, 2292096 A++, 2296253 A++, 2320598 A++, 2347538 A++, 2394007 A++, 2394091 A++, 2394147 A++, 2394151 A++, 2394182 A++, 2394198 A++, 2394290 A++, 2394403 A++, 2394545 A++, 2394613 A++, 2394627 A++, 2394641 A++, 2394703 A++, 2394796 A++, 2394837 A++, 2394917 A++, 2394936 A++, 2394944 A++, 2395037 A++, 2395043 A++, 2395048 A++, 2395124 A++, 2395132 A++, 2395173 A++, 2395197 A++, 2397775 A++, 2407557 A++, 2487705 A++, 2546065 A++, 2605886 A++, 2901753 A++, 2902740 A++, 2912895 A++, 2912945 A++, 2957118 A++, 2965565 A++, 3002012 A++, 3043279 A++, 3078897 A++, 3109789 A++, 3109859 A++, 3109921 A++, 3109928 A++, 3109983 A++, 3110067 A++, 3110148 A++, 3110154 A++, 3110221 A++, 3110339 A++, 3110437 A++, 3110533 A++, 3110548 A++, 3110632 A++, 3110638 A++, 3110656 A++, 3110662 A++, 3110685 A++, 3110732 A++, 3110733 A++, 822650 A++, 1094369 A+++, 1229539 A+++, 1229877 A+++, 1229905 A+++, 1229919 A+++, 1229942 A+++, 1229943 A+++, 1229947 A+++, 1229958 A+++, 1230021 A+++, 1230055 A+++, 1230172 A+++, 1230231 A+++, 1230232 A+++, 1230317 A+++, 1230368 A+++, 1230435 A+++, 1230602 A+++, 1230611 A+++, 1230630 A+++, 1230672 A+++, 1230696 A+++, 1230711 A+++, 1229957 A++++, 1230554 A++++, 1230585 A++++
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
variety Minghui63
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Manually annotated by BRENDA team
variety Zhonghua11
UniProt
Manually annotated by BRENDA team
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
protozoa
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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1105520 A+, 1156981 A+, 1204559 A+, 1204742 A+, 1225819 A+, 1229490 A+, 1229517 A+, 1229634 A+, 1229688 A+, 1229706 A+, 1229766 A+, 1229788 A+, 1229821 A+, 1229837 A+, 1229866 A+, 1229898 A+, 1229956 A+, 1229979 A+, 1229991 A+, 1230000 A+, 1230032 A+, 1230052 A+, 1230053 A+, 1230068 A+, 1230090 A+, 1230105 A+, 1230141 A+, 1230149 A+, 1230159 A+, 1230197 A+, 1230199 A+, 1230208 A+, 1230246 A+, 1230279 A+, 1230284 A+, 1230336 A+, 1230340 A+, 1230343 A+, 1230401 A+, 1230412 A+, 1230422 A+, 1230426 A+, 1230429 A+, 1230430 A+, 1230457 A+, 1230466 A+, 1230472 A+, 1230485 A+, 1230504 A+, 1230505 A+, 1230515 A+, 1230519 A+, 1230527 A+, 1230535 A+, 1230538 A+, 1230553 A+, 1230561 A+, 1230594 A+, 1230600 A+, 1230606 A+, 1230607 A+, 1230637 A+, 1230676 A+, 1230699 A+, 1230713 A+, 1230720 A+, 1230721 A+, 1235348 A+, 1319567 A+, 1539033 A+, 1671721 A+, 1673767 A+, 1728527 A+, 1819650 A+, 1827374 A+, 1839278 A+, 1842496 A+, 1878994 A+, 1888225 A+, 1888349 A+, 1932788 A+, 1936008 A+, 1936359 A+, 1939545 A+, 1978571 A+, 2012441 A+, 2080394 A+, 2080401 A+, 2080465 A+, 2080508 A+, 2080637 A+, 2080790 A+, 2080846 A+, 2080895 A+, 2081055 A+, 2081099 A+, 2081111 A+, 2081249 A+, 2081281 A+, 2081316 A+, 2081320 A+, 2081325 A+, 2081328 A+, 2081369 A+, 2081370 A+, 2081416 A+, 2081478 A+, 2081486 A+, 2081588 A+, 2081591 A+, 2081599 A+, 2081714 A+, 2081716 A+, 2081722 A+, 2195977 A+, 2226022 A+, 2253197 A+, 2274891 A+, 2289260 A+, 2296164 A+, 2373812 A+, 2385490 A+, 2393456 A+, 2393539 A+, 2393540 A+, 2393594 A+, 2393683 A+, 2393882 A+, 2394004 A+, 2394164 A+, 2394395 A+, 2394432 A+, 2394565 A+, 2394750 A+, 2394829 A+, 2394830 A+, 2394833 A+, 2394839 A+, 2394844 A+, 2394847 A+, 2394858 A+, 2394862 A+, 2394888 A+, 2394910 A+, 2394913 A+, 2395128 A+, 2395211 A+, 2395224 A+, 2395237 A+, 2397719 A+, 2406098 A+, 2488011 A+, 2545260 A+, 2658572 A+, 2663379 A+, 2670583 A+, 2686756 A+, 2698647 A+, 2799593 A+, 2864896 A+, 2912816 A+, 2912868 A+, 2956438 A+, 3109398 A+, 3109647 A+, 3109837 A+, 3109839 A+, 3109955 A+, 3110039 A+, 3110082 A+, 3110119 A+, 3110208 A+, 3110327 A+, 3110349 A+, 3110365 A+, 3110469 A+, 3110542 A+, 3110572 A+, 3110636 A+, 3110815 A+, 3110839 A+, 3110876 A+, 3110897 A+, 1230080 A++, 1248991 A++, 1719032 A++, 1730400 A++, 1837152 A++, 1888226 A++, 1921617 A++, 1936346 A++, 2081103 A++, 2081174 A++, 2081549 A++, 2081560 A++, 2128276 A++, 2298492 A++, 2325373 A++, 2347456 A++, 2394055 A++, 2394196 A++, 2394197 A++, 2394256 A++, 2394494 A++, 2394921 A++, 2394927 A++, 2394937 A++, 2395069 A++, 2395075 A++, 2395082 A++, 2395142 A++, 2397827 A++, 2487705 A++, 2808592 A++, 2811300 A++, 2894684 A++, 2912637 A++, 2912689 A++, 2912945 A++, 2971040 A++, 3108622 A++, 3110144 A++, 3110517 A++, 3110564 A++, 3110630 A++, 3110714 A++, 1230203 A++, 1230491 A++, 1230610 A++, 1250478 A++, 1927904 A++, 2080927 A++, 2080971 A++, 2127016 A++, 2324670 A++, 2347412 A++, 2394264 A++, 2394344 A++, 2394689 A++, 2394711 A++, 2394796 A++, 2394931 A++, 2394971 A++, 2395044 A++, 2911894 A++, 2912759 A++, 2938624 A++, 3110237 A++, 3110549 A++, 3110629 A++, 3110656 A++, 712498 A++, 1229502 A+++, 1229762 A+++, 1229825 A+++, 1229835 A+++, 1229849 A+++, 1229901 A+++, 1229939 A+++, 1229986 A+++, 1230121 A+++, 1230155 A+++, 1230173 A+++, 1230184 A+++, 1230207 A+++, 1230223 A+++, 1230235 A+++, 1230242 A+++, 1230322 A+++, 1230349 A+++, 1230351 A+++, 1230356 A+++, 1230434 A+++, 1230436 A+++, 1230459 A+++, 1230465 A+++, 1230471 A+++, 1230507 A+++, 1230512 A+++, 1230543 A+++, 1230549 A+++, 1230574 A+++, 1230576 A+++, 1230581 A+++, 1230631 A+++, 1230646 A+++, 1230650 A+++, 1230710 A+++, 1230718 A+++, 969930 A+++, 1230194 A++++, 1230550 A++++, 1230558 A++++, 1230568 A++++, 1230572 A++++, 1230619 A++++
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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1004794 A+, 1100193 A+, 1187625 A+, 1229506 A+, 1229507 A+, 1229508 A+, 1229509 A+, 1229513 A+, 1229530 A+, 1229531 A+, 1229537 A+, 1229554 A+, 1229557 A+, 1229565 A+, 1229571 A+, 1229582 A+, 1229611 A+, 1229612 A+, 1229627 A+, 1229636 A+, 1229640 A+, 1229644 A+, 1229657 A+, 1229674 A+, 1229747 A+, 1229759 A+, 1229787 A+, 1229792 A+, 1229817 A+, 1229855 A+, 1229894 A+, 1229933 A+, 1230095 A+, 1230127 A+, 1230163 A+, 1230541 A+, 1230544 A+, 1230647 A+, 1235249 A+, 1235280 A+, 1235296 A+, 1247053 A+, 1247057 A+, 1247326 A+, 1247601 A+, 1363127 A+, 1591595 A+, 1662328 A+, 1703865 A+, 1819650 A+, 1878297 A+, 1879029 A+, 1887907 A+, 1887924 A+, 1887956 A+, 1888003 A+, 1888025 A+, 1888074 A+, 1888118 A+, 1888130 A+, 1970030 A+, 2003499 A+, 2005570 A+, 2017335 A+, 2080410 A+, 2080434 A+, 2080467 A+, 2080482 A+, 2080491 A+, 2080494 A+, 2080502 A+, 2080516 A+, 2080517 A+, 2080522 A+, 2080537 A+, 2080568 A+, 2080674 A+, 2080715 A+, 2080788 A+, 2080805 A+, 2080837 A+, 2080843 A+, 2080848 A+, 2080859 A+, 2080964 A+, 2080980 A+, 2080990 A+, 2081063 A+, 2081152 A+, 2081239 A+, 2081306 A+, 2081346 A+, 2081358 A+, 2081595 A+, 2137617 A+, 2292082 A+, 2296017 A+, 2309048 A+, 2322158 A+, 2353433 A+, 2358664 A+, 2358942 A+, 2358965 A+, 2360844 A+, 2393440 A+, 2393447 A+, 2393470 A+, 2393476 A+, 2393484 A+, 2393485 A+, 2393507 A+, 2393543 A+, 2393569 A+, 2393586 A+, 2393602 A+, 2393663 A+, 2393682 A+, 2393684 A+, 2393693 A+, 2393844 A+, 2393847 A+, 2393868 A+, 2393956 A+, 2394148 A+, 2394175 A+, 2394177 A+, 2394192 A+, 2394350 A+, 2394529 A+, 2394590 A+, 2395025 A+, 2396347 A+, 2397710 A+, 2397716 A+, 2397727 A+, 2406698 A+, 2406725 A+, 2406783 A+, 2406978 A+, 2406990 A+, 2407060 A+, 2407088 A+, 2407517 A+, 2407523 A+, 2407530 A+, 2448979 A+, 2469028 A+, 2581630 A+, 2606482 A+, 2684594 A+, 2853075 A+, 2893545 A+, 2902176 A+, 2902177 A+, 2912476 A+, 2958967 A+, 2998325 A+, 3035154 A+, 3035354 A+, 3077243 A+, 3109126 A+, 3109127 A+, 3109137 A+, 3109161 A+, 3109177 A+, 3109191 A+, 3109218 A+, 3109228 A+, 3109269 A+, 3109276 A+, 3109298 A+, 3109300 A+, 3109313 A+, 3109350 A+, 3109394 A+, 3109400 A+, 3109408 A+, 3109414 A+, 3109426 A+, 3109506 A+, 3109600 A+, 3109639 A+, 3109669 A+, 3109671 A+, 3109715 A+, 3109725 A+, 3109802 A+, 3109817 A+, 3109832 A+, 3109841 A+, 3109861 A+, 3109927 A+, 3110122 A+, 3110134 A+, 3110164 A+, 3110215 A+, 3110230 A+, 3110254 A+, 3110597 A+, 3110930 A+, 659934 A+, 662851 A+, 670237 A+, 675906 A+, 677824 A+, 679110 A+, 729638 A+, 788086 A+, 1230596 A++, 2081539 A++, 2394204 A++, 2394505 A++, 2394697 A++, 2394935 A++, 2395167 A++, 2911885 A++, 3110690 A++, 972468 A++, 1342046 A++, 1660404 A++, 1927624 A++, 2012266 A++, 2081065 A++, 2081176 A++, 2081179 A++, 2081362 A++, 2358880 A++, 2394259 A++, 2912669 A++, 3109949 A++, 3110513 A++, 3110704 A++, 886138 A++, 1061868 A+++, 1229487 A+++, 1229489 A+++, 1229492 A+++, 1229494 A+++, 1229495 A+++, 1229499 A+++, 1229501 A+++, 1229511 A+++, 1229526 A+++, 1229532 A+++, 1229533 A+++, 1229550 A+++, 1229552 A+++, 1229562 A+++, 1229570 A+++, 1229572 A+++, 1229586 A+++, 1229601 A+++, 1229637 A+++, 1229833 A+++, 1229897 A+++, 1230004 A+++, 1230066 A+++, 1230233 A+++, 1230193 A++++
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
strain GK24
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Manually annotated by BRENDA team
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
trout
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
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Automatic Mining of ENzyme DAta
GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
evolution
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Set3C is a conserved nuclear complex, Set3 interacts with Hos2
malfunction
metabolism
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nitrative/oxidative stress reduce HDAC2 expression via nitration of distinct tyrosine residues. Peroxynitrite, hydrogen peroxide and cigarette smoke-conditioned medium reduce HDAC2 expression in A549 epithelial cells in vitro. This reduction is due to increased proteasomal degradation following ubiquitination rather than reduction of mRNA expression or stability
physiological function
additional information