Application | Comment | Organism |
---|---|---|
medicine | histone deacetylase 1 is a gene therapy target in pancreatic ductal adenocarcinoma | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
pancreatic ductal adenocarcinoma cell | - |
Homo sapiens | - |
Patu-8988 cell | - |
Homo sapiens | - |
Synonyms | Comment | Organism |
---|---|---|
HDAC1 | - |
Homo sapiens |
histone deacetylase 1 | - |
Homo sapiens |
Organism | Comment | Expression |
---|---|---|
Homo sapiens | histone deacetylase 1 mRNA in pancreatic cancer tissues are significantly higher than in paracancerous tissues | up |
General Information | Comment | Organism |
---|---|---|
malfunction | knockdown of HDAC1 can generate a remarkable defect in proliferation and also can significantly induce apoptosis and S-phase arrest in PaTu-8988 cells | Homo sapiens |
physiological function | the HDAC1 overexpression plays an important role in tumorigenesis of pancreatic cancer | Homo sapiens |