Cloned (Comment) | Organism |
---|---|
expression in U2OS and 293T cells | Homo sapiens |
Protein Variants | Comment | Organism |
---|---|---|
H135A | loss of catalytic activity | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
additional information | isoform HDAC10 is resistant to inhibitors trapoxin B and sodium butyrate | Homo sapiens | |
trichostatin A | - |
Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytoplasm | - |
Homo sapiens | 5737 | - |
nucleus | - |
Homo sapiens | 5634 | - |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
70000 | - |
x * 70000, SDS-PAGE | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | Q969S8 | isoform HDAC10, enzyme is most similar to isoform HDAC6 | - |
Posttranslational Modification | Comment | Organism |
---|---|---|
additional information | sequence contains a potential N-glycosylation site at D616, 3 putative protein kinase C phosphorylation sites, and several putative casein kinase phosphorylation sites | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | isoform HDAC10 represses transcription independent of its deacetylase activity | Homo sapiens | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 70000, SDS-PAGE | Homo sapiens |