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3.5.1.98: histone deacetylase

This is an abbreviated version!
For detailed information about histone deacetylase, go to the full flat file.

Word Map on EC 3.5.1.98

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hydrolysis of an N6-acetyl-lysine residue of a histone to yield a deacetylated histone =

Synonyms

acetyl-lysine deacetylase, AhHDA1, AtHD1, class I acetyl-lysine deacetylase, class I HDAC, class I histone deacetylase, class II Hda1 HDAC, class II histone deacetylase, class IIa HDAC, class IIa histone deacetylase, Clr6, cytoplasmic deacetylase, deacetylase-like amidohydrolase, dRPD3, FB188 HDAH, Glyma.01 g245100, Glyma.04 g000200, Glyma.04 g187000, Glyma.04 g187100, Glyma.05 g012900, Glyma.05 g021400, Glyma.05 g040600, Glyma.05 g192600, Glyma.06 g000100, Glyma.06 g178700, Glyma.11 g000300, Glyma.11 g187800, Glyma.12 g086700, Glyma.12 g188200, Glyma.17 g078000, Glyma.17 g085700, Glyma.17 g120900, Glyma.17 g229600, GmHDA1, GmHDA10, GmHDA11, GmHDA12, GmHDA13, GmHDA14, GmHDA15, GmHDA16, GmHDA17, GmHDA18, GmHDA2, GmHDA3, GmHDA4, GmHDA5, GmHDA6, GmHDA7, GmHDA8, GmHDA9, GmHDAC, HD1B, HD2, HD8, HDA, HDA-1, HDA-2, HDA-3, HDA-4, hda1, HDA15, HDA19, HDA9, HdaA, HDAC, HDAC 11, HDAC 3, HDAC1, HDAC10, HDAC2, HDAC2-1, HDAC2-2, HDAC3, HDAC4, HDAC5, HDAC6, HDAC6p114, HDAC6p131, HDAC7, HDAC8, HDAC9, HDAH, HDLP, HDT1, HDT2, histone deacetylase, histone deacetylase 1, histone deacetylase 10, histone deacetylase 11, histone deacetylase 2, histone deacetylase 3, histone deacetylase 4, histone deacetylase 6, histone deacetylase 7, histone deacetylase 8, histone deacetylase-1, histone deacetylase-7, histone deacetylase-like amidohydrolase, histone deacetylase-like protein, histone deacetylase1, Hos2, HosB, PA3774, pfHDAC-1, RPD3, Set3 complex, Set3C, tubulin deacetylase, zinc-dependent histone deacetylase, Zn(II)-dependent deacetylase, Zn-HDAC

ECTree

     3 Hydrolases
         3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
             3.5.1 In linear amides
                3.5.1.98 histone deacetylase

Cloned

Cloned on EC 3.5.1.98 - histone deacetylase

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CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
28 HDAC genes from soybean genome are identified, which are asymmetrically distributed on 12 chromosomes, genotyping and phylogenetic analysis, genetic structure, real-time quantitative PCR enzyme expression analysis, recombinant expression of YFP-tagged isozymes in transgenic Glycine max, gene GmHDA1 is located on chromosome 1
28 HDAC genes from soybean genome are identified, which are asymmetrically distributed on 12 chromosomes, genotyping and phylogenetic analysis, genetic structure, real-time quantitative PCR enzyme expression analysis, recombinant expression of YFP-tagged isozymes in transgenic Glycine max, gene GmHDA10 is located on chromosome 6
28 HDAC genes from soybean genome are identified, which are asymmetrically distributed on 12 chromosomes, genotyping and phylogenetic analysis, genetic structure, real-time quantitative PCR enzyme expression analysis, recombinant expression of YFP-tagged isozymes in transgenic Glycine max, gene GmHDA11 is located on chromosome 11
28 HDAC genes from soybean genome are identified, which are asymmetrically distributed on 12 chromosomes, genotyping and phylogenetic analysis, genetic structure, real-time quantitative PCR enzyme expression analysis, recombinant expression of YFP-tagged isozymes in transgenic Glycine max, gene GmHDA12 is located on chromosome 11
28 HDAC genes from soybean genome are identified, which are asymmetrically distributed on 12 chromosomes, genotyping and phylogenetic analysis, genetic structure, real-time quantitative PCR enzyme expression analysis, recombinant expression of YFP-tagged isozymes in transgenic Glycine max, gene GmHDA13 is located on chromosome 12
28 HDAC genes from soybean genome are identified, which are asymmetrically distributed on 12 chromosomes, genotyping and phylogenetic analysis, genetic structure, real-time quantitative PCR enzyme expression analysis, recombinant expression of YFP-tagged isozymes in transgenic Glycine max, gene GmHDA14 is located on chromosome 12
28 HDAC genes from soybean genome are identified, which are asymmetrically distributed on 12 chromosomes, genotyping and phylogenetic analysis, genetic structure, real-time quantitative PCR enzyme expression analysis, recombinant expression of YFP-tagged isozymes in transgenic Glycine max, gene GmHDA15 is located on chromosome 17
28 HDAC genes from soybean genome are identified, which are asymmetrically distributed on 12 chromosomes, genotyping and phylogenetic analysis, genetic structure, real-time quantitative PCR enzyme expression analysis, recombinant expression of YFP-tagged isozymes in transgenic Glycine max, gene GmHDA16 is located on chromosome 17
28 HDAC genes from soybean genome are identified, which are asymmetrically distributed on 12 chromosomes, genotyping and phylogenetic analysis, genetic structure, real-time quantitative PCR enzyme expression analysis, recombinant expression of YFP-tagged isozymes in transgenic Glycine max, gene GmHDA17 is located on chromosome 17
28 HDAC genes from soybean genome are identified, which are asymmetrically distributed on 12 chromosomes, genotyping and phylogenetic analysis, genetic structure, real-time quantitative PCR enzyme expression analysis, recombinant expression of YFP-tagged isozymes in transgenic Glycine max, gene GmHDA18 is located on chromosome 17
28 HDAC genes from soybean genome are identified, which are asymmetrically distributed on 12 chromosomes, genotyping and phylogenetic analysis, genetic structure, real-time quantitative PCR enzyme expression analysis, recombinant expression of YFP-tagged isozymes in transgenic Glycine max, gene GmHDA2 is located on chromosome 4
28 HDAC genes from soybean genome are identified, which are asymmetrically distributed on 12 chromosomes, genotyping and phylogenetic analysis, genetic structure, real-time quantitative PCR enzyme expression analysis, recombinant expression of YFP-tagged isozymes in transgenic Glycine max, gene GmHDA3 is located on chromosome 4
28 HDAC genes from soybean genome are identified, which are asymmetrically distributed on 12 chromosomes, genotyping and phylogenetic analysis, genetic structure, real-time quantitative PCR enzyme expression analysis, recombinant expression of YFP-tagged isozymes in transgenic Glycine max, gene GmHDA4 is located on chromosome 4
28 HDAC genes from soybean genome are identified, which are asymmetrically distributed on 12 chromosomes, genotyping and phylogenetic analysis, genetic structure, real-time quantitative PCR enzyme expression analysis, recombinant expression of YFP-tagged isozymes in transgenic Glycine max, gene GmHDA5 is located on chromosome 5
28 HDAC genes from soybean genome are identified, which are asymmetrically distributed on 12 chromosomes, genotyping and phylogenetic analysis, genetic structure, real-time quantitative PCR enzyme expression analysis, recombinant expression of YFP-tagged isozymes in transgenic Glycine max, gene GmHDA6 is located on chromosome 5
28 HDAC genes from soybean genome are identified, which are asymmetrically distributed on 12 chromosomes, genotyping and phylogenetic analysis, genetic structure, real-time quantitative PCR enzyme expression analysis, recombinant expression of YFP-tagged isozymes in transgenic Glycine max, gene GmHDA7 is located on chromosome 5
28 HDAC genes from soybean genome are identified, which are asymmetrically distributed on 12 chromosomes, genotyping and phylogenetic analysis, genetic structure, real-time quantitative PCR enzyme expression analysis, recombinant expression of YFP-tagged isozymes in transgenic Glycine max, gene GmHDA8 is located on chromosome 5
28 HDAC genes from soybean genome are identified, which are asymmetrically distributed on 12 chromosomes, genotyping and phylogenetic analysis, genetic structure, real-time quantitative PCR enzyme expression analysis, recombinant expression of YFP-tagged isozymes in transgenic Glycine max, gene GmHDA9 is located on chromosome 6
a pET20b-derived HDAC8-His expression plasmid with optimized codon usage, pHD2-His, is modified to add a factor Xa cleavage site, generating pHD2-Xa-His
a synthetic gene coding for HDAC1 is optimised for Escherichia coli codon usage, cloning into pBADHisB, generating vector pBAD-rHDAC1, and recombinant overexpression in Escherichia coli strain TOP10, method evaluation. The overexpression of HDAC1 is induced for 15 h at 30°C with 1.3 mM arabinose, when bacterial populations reach an OD600 equal to 0.8-0.9
DNA and amino acid sequence determination and analysis, sequence comparisons, recombinant expression of GST-tagged isozyme HDAC3 in Escherichia coli
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expression in 293 cells
expression in 293T, HeLa and Neuro2A cells
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expression in baculoviral system, His-tagged protein
expression in Escherichia coli
expression in Escherichia coli, GST fusion protein
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expression in HEK-293 cells and Escherichia coli
expression in HeLa and Sf9 cells, FLAG-tagged protein
expression in Sf9 cells of full-length protein and of Gal4-dHDAC1, consisting of the N-terminal 147 amino acid residues of the yeast Gal4 protein fused to the N terminus of full-length dHDAC1 protein
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expression in SV40 T-Ag Jurkat cells
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expression in U2OS and 293T cells
expression of FLAG-tagged enzyme in T-Ag Jurkat cells
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expression of FLAG-tagged protein in 293 cells
expression with FLAG-tag in HEK-293 cells
FLAG-tagged HDAC1 deletion mutants, aa 1-482, 1-140 and 141-482, are constructed in pcDNA3 FLAG expression plasmid
FLAG-tagged protein, expression in C2 or 10T1/2 cells
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full lengtht cDNAs for hdac1 and hdac3 are cloned into the pGEM-T easy vector and confirmed by sequencing, for functional analysis the genes are subcloned into the vector pCS2
full-length HDAC1 with COOH-terminal His tag is expressed using baculovirus expression system
full-length HDAC2 with COOH-terminal His tag is expressed using baculovirus expression system
full-length HDAC3 with COOH-terminal His tag is expressed using baculovirus expression system
full-length HDAC4 with COOH-terminal His tag is expressed using baculovirus expression system
full-length HDAC8 with COOH-terminal His tag is expressed using baculovirus expression system
gene HDA1, DNA and amino acid sequence dteermination and analysis, sequence comparisons and phylogenetic analysis, functional recombinant expression of His-tagged enzyme in Escherichia coli strain BL21, quantitative RT-PCR enzyme expression analysis
gene HDA15, quantitative expression analysis of wild-type and mutant enzymes at 20°C and 27°C in transgenic Arabidosis thaliana lines
gene HDA19, quantitative expression analysis of wild-type and mutant enzymes at 20°C and 27°C in transgenic Arabidosis thaliana lines, recombinant expression of HA-tagged HDA19 in hda19 or hda9-1 mutants via Agrobacterium tumefaciens strain GV3101 transfection using the floral dip method
gene HDA9, quantitative expression analysis of wild-type and mutant enzymes at 20°C and 27°C in transgenic Arabidosis thaliana lines, recombinant expression of HA-tagged HDA9 in hda19 or hda9-1 mutants via Agrobacterium tumefaciens strain GV3101 transfection using the floral dip method
gene HDAC4, histone deacetylase expression within in vitro and in vivo bladder cancer model systems, quantitative real-time PCR enzyme expression analysis, overview. Basal-squamous bladder cancer (BC) clinical samples are enriched for histone deacetylase (HDAC)4 and HDAC9 expression
gene HDAC7, histone deacetylase expression within in vitro and in vivo bladder cancer model systems, quantitative real-time PCR enzyme expression analysis, overview
gene HDAC9, histone deacetylase expression within in vitro and in vivo bladder cancer model systems, quantitative real-time PCR enzyme expression analysis, overview. Basal-squamous bladder cancer clinical samples are enriched for histone deacetylase (HDAC)4 and HDAC9 expression
gene HDT1, expression analysis
gene HDT2, expression analysis
gene HOS2, DNA and amino acid sequence determination and analysis, recombinant expression of N-terminally His6-atgegd enzyme in Spodoptera frugiperda Sf9 cells
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gene pa3774, DNA and amino acid sequence determination and analysis, recombinant expression of wild-type and mutant enzymes
HDAC1 mutants are cloned into pBJ5HDAC1-F
His-tagged expression in Escherichia coli
into the pAc5.1 expression vector for expression in S2 insect cells
isoform HDAC1
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isoform HDAC3, expression in NIH 3T3 fibroblasts
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isoform HDAC8, expression in Escherichia coli
isoform HDAC8, expression in Escherichia coli. Isoforms HDAC1, HDAC6, expression in HEK-293 cell, HDAC3, expression in insect system, FLAg-tagged proteins
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Myc-, HA- or, GFP-tagged HDAC6 are constructed in a CMV promoter-derrived mammalian expression vector, pCS4+
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overexpression in Escherichia coli as glutathione S-transferase fusion protein
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recombinant expression of His-tagged enzyme
recombinant expression of His-tagged isozyme HDAC8
recombinant expression of His-tagged wild-type and mutant ARB2 domains (residues Hda1457-698) in Escherichia coli strain BL21(DE3)
recombinant expression of His6-tagged enzyme in Escherichia coli strain BL21(DE3)
recombinant HDAC1, HDAC8, HDAC6 and HDAC7
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residues 483 to 903 of isoform 1 of chHDAC7 are cloned into a modified pET28a vector for expression in Escherichia coli BL21DE3 Codon Plus RIL cells
stable expression in MCF-7 cell
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transient and stable expression of green fluorescent protein-tagged enzyme in onion cells and roots, seeds and leaves of Arabidopsis. For control of enzymic activity, expression in bacterial cells. Expression in insect cells does not result in catalytically active enzyme