1.1.1.14: L-iditol 2-dehydrogenase

This is an abbreviated version, for detailed information about L-iditol 2-dehydrogenase, go to the full flat file.

Reaction

L-Iditol
+
NAD+
=
L-sorbose
+
NADH
+
H+

Synonyms

ADH, D-sorbitol dehydrogenase, dehydrogenase, L-iditol, Dgeo_2865, glucitol dehydrogenase, Hxt13, Hxt15, Hxt16, Hxt17, L-iditol 2-dehydrogenase, L-iditol dehydrogenase (sorbitol), L-iditol:NAD oxidoreductase, L-iditol:NAD+ 5-oxidoreductase, LeSDH, MdSDH5, More, NAD+-dependent sorbitol dehydrogenase, NAD-dependent polyol dehydrogenase, NAD-dependent sorbitol dehydrogenase, NAD-SDH, NAD-sorbitol dehydrogenase, PDH-11300, polyol dehydrogenase, Protein tms1, SDH, SldA, SLDH, Sor1, Sor2, sorbitol dehydrogenase, sorbitol transporter, SORD

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.14 L-iditol 2-dehydrogenase

KM Value

KM Value on EC 1.1.1.14 - L-iditol 2-dehydrogenase

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KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
15.5
2-deoxy-D-sorbitol
-
-
15.5
2-fluoro-D-sorbitol
-
-
1.9
3-deoxy-D-sorbitol
-
-
15.5
3-fluoro-D-sorbitol
-
-
26.4
4-deoxy-D-sorbitol
-
-
11.7
4-fluoro-D-sorbitol
-
-
0.48
6-deoxy-D-sorbitol
-
-
0.74
6-fluoro-D-sorbitol
-
-
1 - 1500
D-fructose
1.5 - 500
D-galactitol
6.2 - 9.1
D-glucitol
16 - 555
D-mannitol
1.3 - 125
D-ribitol
34 - 260
D-ribulose
0.0032 - 785
D-sorbitol
10 - 13
D-tagatose
0.17 - 37
D-xylitol
1
D-xylulose
-
-
20
L-arabitol
-
-
25
L-erythrulose
-
-
9 - 20
L-Iditol
110 - 800
L-sorbose
268
L-Threitol
-
-
0.041 - 0.6
NAD+
0.007 - 0.28
NADH
0.41
NADP+
substrate-binding loop chimera plus mutation D55N, pH 9.0, temperature not specified in the publication
additional information
additional information
-
kinetic mechanism
-