1.1.1.14: L-iditol 2-dehydrogenase

This is an abbreviated version, for detailed information about L-iditol 2-dehydrogenase, go to the full flat file.

Reaction

L-Iditol
+
NAD+
=
L-sorbose
+
NADH
+
H+

Synonyms

ADH, D-sorbitol dehydrogenase, dehydrogenase, L-iditol, Dgeo_2865, glucitol dehydrogenase, Hxt13, Hxt15, Hxt16, Hxt17, L-iditol 2-dehydrogenase, L-iditol dehydrogenase (sorbitol), L-iditol:NAD oxidoreductase, L-iditol:NAD+ 5-oxidoreductase, LeSDH, MdSDH5, More, NAD+-dependent sorbitol dehydrogenase, NAD-dependent polyol dehydrogenase, NAD-dependent sorbitol dehydrogenase, NAD-SDH, NAD-sorbitol dehydrogenase, PDH-11300, polyol dehydrogenase, Protein tms1, SDH, SldA, SLDH, Sor1, Sor2, sorbitol dehydrogenase, sorbitol transporter, SORD

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.14 L-iditol 2-dehydrogenase

General Stability

General Stability on EC 1.1.1.14 - L-iditol 2-dehydrogenase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
GENERAL STABILITY
ORGANISM
UNIPROT
LITERATURE
0.1 mg/ml bovine serum albumin stabilizes at -20C
-
0.1 mg/ml bovine serum albumin stabilizes at 4C
-
0.1 mg/ml bovine serum albumin stabilizes at room temperature
-
1 mM dithiothreitol reduces stability
-
278 mM maltose stabilizes at 4C
-
30% sucrose stabilizes
6.8 M glycerol stabilizes at 4C
-
alpha-crystallin stabilizes
-
bovine serum albumin stabilizes
-
bovine serum albumin stabilizes at 4C
-
complete renaturation, alpha-crystallin has the ability to elicit protein refolding. This action of alpha-crystallin appears not to be dependent on ATP as energy donor, but essentially associated with intrinsic structural features of this chaperone molecule
-
dithioerythritol protects at 1 mM, inhibits at 100 mM
-
dithiothreitol protects at 1 mM at 4C
-
freezing to -20C, loss of activity
-
freezing, loss of activity
-
Triton X-100, 1%, and D-sorbitol stabilize the enzyme during solubilization and purification, while n-octyl-beta-D-glucopyranoside does not
-