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Information on EC 3.4.24.3 - microbial collagenase

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EC Tree
     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.24 Metalloendopeptidases
                3.4.24.3 microbial collagenase
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Word Map
The enzyme appears in viruses and cellular organisms
Reaction Schemes
Digestion of native collagen in the triple helical region at -/-Gly bonds. With synthetic peptides, a preference is shown for Gly at P3 and P1', Pro and Ala at P2 and P2', and hydroxyproline, Ala or Arg at P3'
Synonyms
bacterial collagenase, collagenase i, clostridium histolyticum collagenase, collagenase g, collagenase h, collagenase t, collagen protease, thermophilic collagenolytic protease, clostridial collagenase a, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
Digestion of native collagen in the triple helical region at -/-Gly bonds. With synthetic peptides, a preference is shown for Gly at P3 and P1', Pro and Ala at P2 and P2', and hydroxyproline, Ala or Arg at P3'
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