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Literature summary for 3.4.24.3 extracted from

  • Appel, W.
    Kollagenasen (1974), Methods Enzym. Anal. , 3rd Ed. (Bergmeyer, H. U. , ed. ), 1, 1098-1104.
No PubMed abstract available

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
Collagen + H2O Pseudomonas aeruginosa degradation of helical regions of native collagen to small fragments, preferential cleavage: -Gly in the sequence Pro-Xaa-Gly-Pro ?
-
?
Collagen + H2O Mycobacterium tuberculosis degradation of helical regions of native collagen to small fragments, preferential cleavage: -Gly in the sequence Pro-Xaa-Gly-Pro ?
-
?
Collagen + H2O Clostridium perfringens degradation of helical regions of native collagen to small fragments, preferential cleavage: -Gly in the sequence Pro-Xaa-Gly-Pro ?
-
?
Collagen + H2O Clostridium capitorale degradation of helical regions of native collagen to small fragments, preferential cleavage: -Gly in the sequence Pro-Xaa-Gly-Pro ?
-
?
Collagen + H2O Clostridium welchii degradation of helical regions of native collagen to small fragments, preferential cleavage: -Gly in the sequence Pro-Xaa-Gly-Pro ?
-
?
Collagen + H2O Hathewaya histolytica degradation of helical regions of native collagen to small fragments, preferential cleavage: -Gly in the sequence Pro-Xaa-Gly-Pro ?
-
?

Organism

Organism UniProt Comment Textmining
Clostridium capitorale
-
-
-
Clostridium perfringens
-
-
-
Clostridium welchii
-
-
-
Hathewaya histolytica
-
-
-
Mycobacterium tuberculosis
-
-
-
Pseudomonas aeruginosa
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Collagen + H2O degradation of helical regions of native collagen to small fragments, preferential cleavage: -Gly in the sequence-Pro-Xaa-Gly-Pro, nondenatured triple helical form Pseudomonas aeruginosa Hydrolyzed collagen
-
?
Collagen + H2O degradation of helical regions of native collagen to small fragments, preferential cleavage: -Gly in the sequence-Pro-Xaa-Gly-Pro, nondenatured triple helical form Mycobacterium tuberculosis Hydrolyzed collagen
-
?
Collagen + H2O degradation of helical regions of native collagen to small fragments, preferential cleavage: -Gly in the sequence-Pro-Xaa-Gly-Pro, nondenatured triple helical form Clostridium perfringens Hydrolyzed collagen
-
?
Collagen + H2O degradation of helical regions of native collagen to small fragments, preferential cleavage: -Gly in the sequence-Pro-Xaa-Gly-Pro, nondenatured triple helical form Clostridium capitorale Hydrolyzed collagen
-
?
Collagen + H2O degradation of helical regions of native collagen to small fragments, preferential cleavage: -Gly in the sequence-Pro-Xaa-Gly-Pro, nondenatured triple helical form Clostridium welchii Hydrolyzed collagen
-
?
Collagen + H2O degradation of helical regions of native collagen to small fragments, preferential cleavage: -Gly in the sequence-Pro-Xaa-Gly-Pro, nondenatured triple helical form Hathewaya histolytica Hydrolyzed collagen
-
?
Collagen + H2O degradation of helical regions of native collagen to small fragments, preferential cleavage: -Gly in the sequence Pro-Xaa-Gly-Pro Pseudomonas aeruginosa ?
-
?
Collagen + H2O degradation of helical regions of native collagen to small fragments, preferential cleavage: -Gly in the sequence Pro-Xaa-Gly-Pro Mycobacterium tuberculosis ?
-
?
Collagen + H2O degradation of helical regions of native collagen to small fragments, preferential cleavage: -Gly in the sequence Pro-Xaa-Gly-Pro Clostridium perfringens ?
-
?
Collagen + H2O degradation of helical regions of native collagen to small fragments, preferential cleavage: -Gly in the sequence Pro-Xaa-Gly-Pro Clostridium capitorale ?
-
?
Collagen + H2O degradation of helical regions of native collagen to small fragments, preferential cleavage: -Gly in the sequence Pro-Xaa-Gly-Pro Clostridium welchii ?
-
?
Collagen + H2O degradation of helical regions of native collagen to small fragments, preferential cleavage: -Gly in the sequence Pro-Xaa-Gly-Pro Hathewaya histolytica ?
-
?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
6.5 8.8
-
Pseudomonas aeruginosa
6.5 8.8
-
Mycobacterium tuberculosis
6.5 8.8
-
Clostridium perfringens
6.5 8.8
-
Clostridium capitorale
6.5 8.8
-
Clostridium welchii
6.5 8.8
-
Hathewaya histolytica