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Literature summary for 3.4.24.3 extracted from

  • Yi, E.; Sato, S.; Takahashi, A.; Parameswaran, H.; Blute, T.A.; Bartolak-Suki, E.; Suki, B.
    Mechanical forces accelerate collagen digestion by bacterial collagenase in lung tissue strips (2016), Front. Physiol., 7, 287 .
    View publication on PubMedView publication on EuropePMC

Organism

Organism UniProt Comment Textmining
Hathewaya histolytica
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Source Tissue

Source Tissue Comment Organism Textmining
commercial preparation
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Hathewaya histolytica
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Synonyms

Synonyms Comment Organism
bacterial collagenase
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Hathewaya histolytica
collagenase
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Hathewaya histolytica

General Information

General Information Comment Organism
physiological function the bacterial collagenase affects the extracellular matrix (ECM) in the lungs of C57BL/6 mice. Mechanical loading increases the effects of enzyme activity characterized by an irreversible decline in stiffness and tissue deterioration. Physiological levels of mechanical forces are capable of modifying the activity of collagenase, a key remodeling enzyme of the ECM. Role of collagen degradation in general tissue remodeling and disease progression, overview Hathewaya histolytica