EC Number   |
Natural Substrates |
|---|
   3.4.24.3 | Collagen + H2O |
- |
| 3.4.24.3 | Collagen + H2O |
degradation of helical regions of native collagen to small fragments, preferential cleavage: -Gly in the sequence Pro-Xaa-Gly-Pro |
| 3.4.24.3 | Collagen + H2O |
clostridial collagenase A is effective in degrading collagen in eschar tissue and promoting healing in partial-thickness burns, CCA aggravates the systemic inflammatory response in rats with partial-thickness burns, inflammatory reactions such as fever, leukocytosis or leukocytopenia and increased CRP levels in sera are often observed in a significant proportion of burn victims treated with CCA ointment, although synchronous wound swab cultures show no signs of infection, overview |
| 3.4.24.3 | Collagen + H2O |
proteolytic degradation, the enzyme helps the skin to heal after burns and dermal ulcers, but can cause allergic reactions, overview |
| 3.4.24.3 | Collagen + H2O |
type II collagenase ColH acts inside of the collagen triple helix molecule |
| 3.4.24.3 | Collagen type I + H2O |
- |
| 3.4.24.3 | Collagen type I + H2O |
type I collagenase ColG acts on the N-terminal level of the triple helix of collagen |
| 3.4.24.3 | collagen type II + H2O |
- |
| 3.4.24.3 | Collagen type III + H2O |
- |
| 3.4.24.3 | Gelatin + H2O |
- |
