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6.2.1.3: long-chain-fatty-acid-CoA ligase

This is an abbreviated version!
For detailed information about long-chain-fatty-acid-CoA ligase, go to the full flat file.

Word Map on EC 6.2.1.3

Reaction

ATP
+
a long-chain fatty acid
+
CoA
=
AMP
+
diphosphate
+
a long-chain fatty acyl-CoA

Synonyms

Abll, ACS, ACS-3, ACS-5, ACS1, ACS2, ACS3, ACS4, ACS5, ACS6, AcsA, ACSL, ACSL1, ACSL2, ACSL3, ACSL4, ACSL5, ACSL6, ACSL6 protein, ACSL6_v1, ACSL6_v2, ACSL6_v3, ACSL6_v5, ACSL6_v6, Acsvl1, Acyl coenzyme A synthetase, Acyl-activating enzyme, Acyl-CoA ligase, acyl-CoA synthase-3, Acyl-CoA synthetase, Acyl-CoA synthetase 3, acyl-CoA synthetase 4, acyl-CoA synthetase 5, acyl-CoA synthetase long-chain, acyl-CoA synthetase long-chain family member 4, acyl-CoA synthetase-1, Acyl-coenzyme A ligase, BGR, bubblegum-related protein, CG6178, dAcsl, FAA1, Faa1p, Faa2p, Faa3p, Faa4p, FaaA, FaaB, Facl1, Facl2, FACL3, FACL3/ACS3, FACL4, FACS, FAdD, FadD2, Fat1p, Fat2p, FatA, FatB, FatC, FatD, FATP, FATP2, FATP4, Fatty acid CoA ligase, fatty acid CoA ligase: AMP forming, fatty acid CoA synthetase, AMP forming, fatty acid thiokinase, Fatty acid thiokinase (long chain), fatty acid transport protein, fatty acid transport protein 2, fatty acid transport protein 4, fatty acid-CoA ligase 4, fatty acid:CoA ligase, AMP-forming, fatty acyl-CoA synthetase, Fatty acyl-coenzyme A synthetase, Fatty-acyl-CoA ligase, gonadotropin-regulated long chain acyl-CoA synthetase, gonadotropin-regulated long-chain acyl CoA synthetase, GR-LACS, LACS, LACS1, LACS2, LACS3, LACS4, LACS6, LACS7, LACS9, LC-FACS, LCFA synthetase, LCFACoAS, lipidosin, long chain acyl-CoA synthetase, long chain acyl-CoA synthetase 1, long chain acyl-CoA synthetase 2, long chain acyl-CoA synthetase 3, long chain acyl-CoA synthetase 4, long chain acyl-CoA synthetase 5, Long chain fatty acyl CoA ligase, Long chain fatty acyl-CoA synthetase, long chain fatty acyl-CoA synthetase 5, long fatty acyl-CoA synthetase, Long-chain acyl CoA synthetase, long-chain acyl coenzyme A synthetase 1, long-chain acyl-CoA synthetase, long-chain acyl-CoA synthetase 1, long-chain acyl-CoA synthetase 4, long-chain acyl-CoA synthetase 5, long-chain acyl-CoA synthetase 6, Long-chain acyl-CoA synthetase I, Long-chain acyl-CoA synthetase II, long-chain acyl-CoA synthetase-1, long-chain acyl-CoA synthetases, Long-chain acyl-coenzyme A synthetase, long-chain fatty acid CoA ligase, long-chain fatty acid:CoA ligase, long-chain fatty acyl coenzyme A ligase, Long-chain fatty acyl coenzyme A synthetase, long-chain fatty acyl-CoA synthetase, long-chain fatty-acid-CoA ligase 3, long-chain polyunsaturated fatty acid acyl-coenzyme A synthetase, luciferase-like gene, luciferase-like protein, mACS4, MenE, More, Oleoyl-CoA synthetase, OPC-8:CoA ligase, OPCL1, Palmitoyl coenzyme A synthetase, Palmitoyl-CoA ligase, Palmityl-coenzyme A synthetase, PhpLL1, Pristanoyl-CoA synthetase, protein At1g20510, putative long-chain acyl-CoA synthetase, R-ibuprofenoyl-CoA synthetase, Stearoyl-CoA synthetase, TbACS1, TbACS3, TbACS4, Thiokinase, very long chain acyl-CoA synthetase 1, YBR041W, YBR222C, YER015W

ECTree

     6 Ligases
         6.2 Forming carbon-sulfur bonds
             6.2.1 Acid-thiol ligases
                6.2.1.3 long-chain-fatty-acid-CoA ligase

Source Tissue

Source Tissue on EC 6.2.1.3 - long-chain-fatty-acid-CoA ligase

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SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SOURCE
-
tissue expression patterns of acs-3, overview
Manually annotated by BRENDA team
-
type II cell
Manually annotated by BRENDA team
-
highly expressed in vascular endothelium
Manually annotated by BRENDA team
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coronary microvessel, cell culture
Manually annotated by BRENDA team
-
low FACT3 expression level
Manually annotated by BRENDA team
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highly expressed in vascular endothelium of heart and aorta
Manually annotated by BRENDA team
-
highest expression level in enterocytes at the villus tip
Manually annotated by BRENDA team
-
isoenzyme LACS2
Manually annotated by BRENDA team
high expression level of ACSL4
Manually annotated by BRENDA team
-
tissue expression patterns of acs-3, overview
Manually annotated by BRENDA team
-
peritoneal
Manually annotated by BRENDA team
-
low FACT3 expression level
Manually annotated by BRENDA team
-
-
Manually annotated by BRENDA team
-
aortic, levels of isozymes ACSL1, ACSL3, and ACSL5, overview
Manually annotated by BRENDA team
-
-
Manually annotated by BRENDA team
-
-
Manually annotated by BRENDA team
additional information