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Literature summary for 6.2.1.3 extracted from

  • Normann, P.T.; Norseth, J.; Flatmark, T.
    Acyl-CoA synthetase activity of rat heart mitochondria. Substrate specificity with special reference to very-long-chain and isomeric fatty acids (1983), Biochim. Biophys. Acta, 752, 474-481.
    View publication on PubMed

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion
-
Rattus norvegicus 5739
-

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+ most effective activator of all cations Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
heart
-
Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + laurate + CoA
-
Rattus norvegicus AMP + diphosphate + lauroyl-CoA
-
?
ATP + long-chain carboxylic acid + CoA 18:1 Rattus norvegicus AMP + diphosphate + long-chain acyl-CoA
-
?
ATP + long-chain carboxylic acid + CoA among the saturated fatty acids highest activity is obtained with 12:0 fatty acid, monounsaturated fatty acids (16:1, 18:1, 20:1 and 22:1) are equally good or slightly better substrates than the corresponding saturated fatty acids, polyunsaturated fatty acids are rather poor substrates Rattus norvegicus AMP + diphosphate + long-chain acyl-CoA
-
?
ATP + palmitate + CoA
-
Rattus norvegicus AMP + diphosphate + palmitoyl-CoA
-
?
ATP + stearate + CoA
-
Rattus norvegicus AMP + diphosphate + stearoyl-CoA
-
?