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6.2.1.3: long-chain-fatty-acid-CoA ligase

This is an abbreviated version!
For detailed information about long-chain-fatty-acid-CoA ligase, go to the full flat file.

Word Map on EC 6.2.1.3

Reaction

ATP
+
a long-chain fatty acid
+
CoA
=
AMP
+
diphosphate
+
a long-chain fatty acyl-CoA

Synonyms

Abll, ACS, ACS-3, ACS-5, ACS1, ACS2, ACS3, ACS4, ACS5, ACS6, AcsA, ACSL, ACSL1, ACSL2, ACSL3, ACSL4, ACSL5, ACSL6, ACSL6 protein, ACSL6_v1, ACSL6_v2, ACSL6_v3, ACSL6_v5, ACSL6_v6, Acsvl1, Acyl coenzyme A synthetase, Acyl-activating enzyme, Acyl-CoA ligase, acyl-CoA synthase-3, Acyl-CoA synthetase, Acyl-CoA synthetase 3, acyl-CoA synthetase 4, acyl-CoA synthetase 5, acyl-CoA synthetase long-chain, acyl-CoA synthetase long-chain family member 4, acyl-CoA synthetase-1, Acyl-coenzyme A ligase, BGR, bubblegum-related protein, CG6178, dAcsl, FAA1, Faa1p, Faa2p, Faa3p, Faa4p, FaaA, FaaB, Facl1, Facl2, FACL3, FACL3/ACS3, FACL4, FACS, FAdD, FadD2, Fat1p, Fat2p, FatA, FatB, FatC, FatD, FATP, FATP2, FATP4, Fatty acid CoA ligase, fatty acid CoA ligase: AMP forming, fatty acid CoA synthetase, AMP forming, fatty acid thiokinase, Fatty acid thiokinase (long chain), fatty acid transport protein, fatty acid transport protein 2, fatty acid transport protein 4, fatty acid-CoA ligase 4, fatty acid:CoA ligase, AMP-forming, fatty acyl-CoA synthetase, Fatty acyl-coenzyme A synthetase, Fatty-acyl-CoA ligase, gonadotropin-regulated long chain acyl-CoA synthetase, gonadotropin-regulated long-chain acyl CoA synthetase, GR-LACS, LACS, LACS1, LACS2, LACS3, LACS4, LACS6, LACS7, LACS9, LC-FACS, LCFA synthetase, LCFACoAS, lipidosin, long chain acyl-CoA synthetase, long chain acyl-CoA synthetase 1, long chain acyl-CoA synthetase 2, long chain acyl-CoA synthetase 3, long chain acyl-CoA synthetase 4, long chain acyl-CoA synthetase 5, Long chain fatty acyl CoA ligase, Long chain fatty acyl-CoA synthetase, long chain fatty acyl-CoA synthetase 5, long fatty acyl-CoA synthetase, Long-chain acyl CoA synthetase, long-chain acyl coenzyme A synthetase 1, long-chain acyl-CoA synthetase, long-chain acyl-CoA synthetase 1, long-chain acyl-CoA synthetase 4, long-chain acyl-CoA synthetase 5, long-chain acyl-CoA synthetase 6, Long-chain acyl-CoA synthetase I, Long-chain acyl-CoA synthetase II, long-chain acyl-CoA synthetase-1, long-chain acyl-CoA synthetases, Long-chain acyl-coenzyme A synthetase, long-chain fatty acid CoA ligase, long-chain fatty acid:CoA ligase, long-chain fatty acyl coenzyme A ligase, Long-chain fatty acyl coenzyme A synthetase, long-chain fatty acyl-CoA synthetase, long-chain fatty-acid-CoA ligase 3, long-chain polyunsaturated fatty acid acyl-coenzyme A synthetase, luciferase-like gene, luciferase-like protein, mACS4, MenE, More, Oleoyl-CoA synthetase, OPC-8:CoA ligase, OPCL1, Palmitoyl coenzyme A synthetase, Palmitoyl-CoA ligase, Palmityl-coenzyme A synthetase, PhpLL1, Pristanoyl-CoA synthetase, protein At1g20510, putative long-chain acyl-CoA synthetase, R-ibuprofenoyl-CoA synthetase, Stearoyl-CoA synthetase, TbACS1, TbACS3, TbACS4, Thiokinase, very long chain acyl-CoA synthetase 1, YBR041W, YBR222C, YER015W

ECTree

     6 Ligases
         6.2 Forming carbon-sulfur bonds
             6.2.1 Acid-thiol ligases
                6.2.1.3 long-chain-fatty-acid-CoA ligase

Activating Compound

Activating Compound on EC 6.2.1.3 - long-chain-fatty-acid-CoA ligase

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ACTIVATING COMPOUND
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
alpha-synuclein
-
0.0063-0.634 mM
-
phosphatidylcholine
-
absolute requirement, acyl-CoA synthetase II
phosphatidylethanolamine
-
slight stimulation, acyl-CoA synthetase II
phosphatidylserine
-
slight stimulation, acyl-CoA synthetase II
Triacsin C
ACSL activity is 17fold higher in the presence of 0.02 mM triacsin C
Triton X-100
additional information
-