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6.2.1.3: long-chain-fatty-acid-CoA ligase

This is an abbreviated version!
For detailed information about long-chain-fatty-acid-CoA ligase, go to the full flat file.

Word Map on EC 6.2.1.3

Reaction

ATP
+
a long-chain fatty acid
 +
CoA
=
AMP
 +
diphosphate
 +
a long-chain fatty acyl-CoA

Synonyms

Abll, ACS, ACS-3, ACS-5, ACS1, ACS2, ACS3, ACS4, ACS5, ACS6, AcsA, ACSL, ACSL1, ACSL2, ACSL3, ACSL4, ACSL5, ACSL6, ACSL6 protein, ACSL6_v1, ACSL6_v2, ACSL6_v3, ACSL6_v5, ACSL6_v6, Acsvl1, Acyl coenzyme A synthetase, Acyl-activating enzyme, Acyl-CoA ligase, acyl-CoA synthase-3, Acyl-CoA synthetase, Acyl-CoA synthetase 3, acyl-CoA synthetase 4, acyl-CoA synthetase 5, acyl-CoA synthetase long-chain, acyl-CoA synthetase long-chain family member 4, acyl-CoA synthetase-1, Acyl-coenzyme A ligase, BGR, bubblegum-related protein, CG6178, dAcsl, FAA1, Faa1p, Faa2p, Faa3p, Faa4p, FaaA, FaaB, Facl1, Facl2, FACL3, FACL3/ACS3, FACL4, FACS, FAdD, FadD2, Fat1p, Fat2p, FatA, FatB, FatC, FatD, FATP, FATP2, FATP4, Fatty acid CoA ligase, fatty acid CoA ligase: AMP forming, fatty acid CoA synthetase, AMP forming, fatty acid thiokinase, Fatty acid thiokinase (long chain), fatty acid transport protein, fatty acid transport protein 2, fatty acid transport protein 4, fatty acid-CoA ligase 4, fatty acid:CoA ligase, AMP-forming, fatty acyl-CoA synthetase, Fatty acyl-coenzyme A synthetase, Fatty-acyl-CoA ligase, gonadotropin-regulated long chain acyl-CoA synthetase, gonadotropin-regulated long-chain acyl CoA synthetase, GR-LACS, LACS, LACS1, LACS2, LACS3, LACS4, LACS6, LACS7, LACS9, LC-FACS, LCFA synthetase, LCFACoAS, lipidosin, long chain acyl-CoA synthetase, long chain acyl-CoA synthetase 1, long chain acyl-CoA synthetase 2, long chain acyl-CoA synthetase 3, long chain acyl-CoA synthetase 4, long chain acyl-CoA synthetase 5, Long chain fatty acyl CoA ligase, Long chain fatty acyl-CoA synthetase, long chain fatty acyl-CoA synthetase 5, long fatty acyl-CoA synthetase, Long-chain acyl CoA synthetase, long-chain acyl coenzyme A synthetase 1, long-chain acyl-CoA synthetase, long-chain acyl-CoA synthetase 1, long-chain acyl-CoA synthetase 4, long-chain acyl-CoA synthetase 5, long-chain acyl-CoA synthetase 6, Long-chain acyl-CoA synthetase I, Long-chain acyl-CoA synthetase II, long-chain acyl-CoA synthetase-1, long-chain acyl-CoA synthetases, Long-chain acyl-coenzyme A synthetase, long-chain fatty acid CoA ligase, long-chain fatty acid:CoA ligase, long-chain fatty acyl coenzyme A ligase, Long-chain fatty acyl coenzyme A synthetase, long-chain fatty acyl-CoA synthetase, long-chain fatty-acid-CoA ligase 3, long-chain polyunsaturated fatty acid acyl-coenzyme A synthetase, luciferase-like gene, luciferase-like protein, mACS4, MenE, More, Oleoyl-CoA synthetase, OPC-8:CoA ligase, OPCL1, Palmitoyl coenzyme A synthetase, Palmitoyl-CoA ligase, Palmityl-coenzyme A synthetase, PhpLL1, Pristanoyl-CoA synthetase, protein At1g20510, putative long-chain acyl-CoA synthetase, R-ibuprofenoyl-CoA synthetase, Stearoyl-CoA synthetase, TbACS1, TbACS3, TbACS4, Thiokinase, very long chain acyl-CoA synthetase 1, YBR041W, YBR222C, YER015W

ECTree

     6 Ligases
         6.2 Forming carbon-sulfur bonds
             6.2.1 Acid-thiol ligases
                6.2.1.3 long-chain-fatty-acid-CoA ligase

Molecular Weight

Molecular Weight on EC 6.2.1.3 - long-chain-fatty-acid-CoA ligase

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MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
118000
-
gel filtration
130000
-
gel filtration, gradient PAGE
145000
-
gel filtration
150000
250000
-
aggregates quite readily to form species with MW of over 1 million, gel filtration
42000
-
x * 42000, SDS-PAGE
45000 - 47000
-
gel filtration
47000
50000
-
sedimentation equilibrium ultracentrifugation
59000
-
2 * 59000, SDS-PAGE
62028
-
x * 62028, calculation from nucleotide sequence
64000
72000
predicted molecular mass
72500
-
2 * 72500, gel filtration
74000
-
2 * 74000, SDS-PAGE
75000
76000
77870
calculated from amino acid sequence
78000
SDS-PAGE
78177
-
x * 78177, liver enzyme, caculation from nucleotide sequence
79000
80000
-
SDS-PAGE
81516
-
x * 81516, calculation from nucleotide sequence
84000
-
x * 84000, SDS-PAGE, enzyme form acyl-CoA synthetase I