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Literature summary for 6.2.1.3 extracted from

  • Nchoutmboube, J.A.; Viktorova, E.G.; Scott, A.J.; Ford, L.A.; Pei, Z.; Watkins, P.A.; Ernst, R.K.; Belov, G.A.
    Increased long chain acyl-CoA synthetase activity and fatty acid import is linked to membrane synthesis for development of picornavirus replication organelles (2013), PLoS Pathog., 9, e1003401.
    View publication on PubMedView publication on EuropePMC

Localization

Localization Comment Organism GeneOntology No. Textmining

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
HeLa cell
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + Bodipy 500/510 C4-C9 + CoA
-
Homo sapiens ?
-
?

Synonyms

Synonyms Comment Organism
ACSL3
-
Homo sapiens
FATP
-
Homo sapiens
long chain acyl-CoA synthetase 3
-
Homo sapiens

Cofactor

Cofactor Comment Organism Structure
ATP
-
Homo sapiens

Expression

Organism Comment Expression
Homo sapiens long chain acyl-CoA synthetase activity is upregulated in poliovirus-infected cells up

General Information

General Information Comment Organism
physiological function isoform Acsl3 is required to support effective poliovirus replication Homo sapiens