Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
mitochondrial membrane | - |
Mus musculus | 31966 | - |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
74000 | - |
2 * 74000, SDS-PAGE | Mus musculus |
150000 | - |
gel filtration | Mus musculus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + arachidonate + CoA | Mus musculus | preferred substrate | AMP + diphosphate + arachidonoyl-CoA | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Posttranslational Modification | Comment | Organism |
---|---|---|
phosphoprotein | the phosphorylation of the enzyme by protein kinase A and protein kinase C is hormone-dependent. Phosphorylation occurs after active dimer formation | Mus musculus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
adrenocortical tumor cell | - |
Mus musculus | - |
Y-1 cell | - |
Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + arachidonate + CoA | preferred substrate | Mus musculus | AMP + diphosphate + arachidonoyl-CoA | - |
? |
Subunits | Comment | Organism |
---|---|---|
homodimer | 2 * 74000, SDS-PAGE | Mus musculus |
Synonyms | Comment | Organism |
---|---|---|
ACSL4 | - |
Mus musculus |
long-chain acyl-CoA synthetase 4 | - |
Mus musculus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | - |
Mus musculus |
General Information | Comment | Organism |
---|---|---|
metabolism | long chain acyl CoA synthetase 4 is a key enzyme in steroidogenesis. It participates in steroid synthesis through of arachidonic acid release and steroidogenic acute regulatory protein induction | Mus musculus |