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3.4.24.11: neprilysin

This is an abbreviated version!
For detailed information about neprilysin, go to the full flat file.

Word Map on EC 3.4.24.11

Reaction

preferential cleavage of polypeptides between hydrophobic residues, particularly with Phe or Tyr at P1' =

Synonyms

Abeta-degrading enzyme, acute lymphoblastic leukemia antigen, antigen, CALLA (common acute lymphoblastic leukemia-associated), atriopeptidase, CALLA, CALLA (common acute lymphoblastic leukemia-associated) antigens, CALLA antigen, CALLA glycoproteins, CD10, CD10/neutral endopeptidase, CD10/neutral endopeptidase 24.11, common acute lymphoblastic leukemia antigen, common acute lymphoblastic leukemia-associated antigens, Common acute lymphocytic leukemia antigen, endopeptidase CD10, Endopeptidase-2, endopeptidase-24.11, enkephalinase, EP24.11, glycoprotein, CALLA, kidney-brush-border neutral endopeptidase, kidney-brush-border neutral peptidase, kidney-brush-border neutral proteinase, membrane metallo-endopeptidase, membrane metalloendopeptidase, MME, NEP, NEP 24.11, NEP, enkephalinase, neutrophil cluster-differentiation antigen 10, common acute lymphoblastic leukemia antigen, NEP-1, NEP/CD10, NEP2, NEP4A, NEP4B, neprilypsin, neprilysin, neprilysin 4, neutral endopeptidase, neutral endopeptidase 24.11, neutral endopeptidase 24.11/CD10, neutral metallendopeptidase, NL-1, peptidase, endo-, peptidase, membrane metalloendo-, SEP, skin fibroblast elastase

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.24 Metalloendopeptidases
                3.4.24.11 neprilysin

Synonyms

Synonyms on EC 3.4.24.11 - neprilysin

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SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
Abeta-degrading enzyme
-
acute lymphoblastic leukemia antigen
-
-
antigen, CALLA (common acute lymphoblastic leukemia-associated)
-
-
-
-
atriopeptidase
-
CALLA
CALLA (common acute lymphoblastic leukemia-associated) antigens
-
-
-
-
CALLA antigen
-
-
-
-
CALLA glycoproteins
-
-
-
-
CD10/neutral endopeptidase
-
-
CD10/neutral endopeptidase 24.11
-
-
common acute lymphoblastic leukemia antigen
common acute lymphoblastic leukemia-associated antigens
-
-
-
-
Common acute lymphocytic leukemia antigen
-
-
-
-
endopeptidase CD10
-
-
Endopeptidase-2
-
-
-
-
endopeptidase-24.11
enkephalinase
EP24.11
-
-
glycoprotein, CALLA
-
-
-
-
kidney-brush-border neutral endopeptidase
-
-
-
-
kidney-brush-border neutral peptidase
-
-
-
-
kidney-brush-border neutral proteinase
-
-
-
-
membrane metallo-endopeptidase
-
membrane metalloendopeptidase
-
-
-
-
NEP 24.11
-
-
NEP, enkephalinase, neutrophil cluster-differentiation antigen 10, common acute lymphoblastic leukemia antigen
-
-
NEP/CD10
-
-
NEP2
-
-
neprilypsin
-
-
neprilysin
neprilysin 4
Q9I7I4
two isoforms exist due to different splice-variants: larger isoform A is expressed as a membrane bound protein and isoform B lacking the N-terminal cytosolic and transmembrane region is expressed as a soluble protein
neutral endopeptidase
neutral endopeptidase 24.11
neutral endopeptidase 24.11/CD10
-
-
neutral metallendopeptidase
-
-
-
-
NL-1
-
-
peptidase, endo-
-
-
-
-
peptidase, membrane metalloendo-
-
-
-
-
skin fibroblast elastase