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Literature summary for 3.4.24.11 extracted from

  • Sansoe, G.; Aragno, M.; Mastrocola, R.; Cutrin, J.C.; Silvano, S.; Mengozzi, G.; Smedile, A.; Rosina, F.; Danni, O.; Rizzetto, M.
    Overexpression of kidney neutral endopeptidase (EC 3.4.24.11) and renal function in experimental cirrhosis (2006), Am. J. Physiol. Renal Physiol., 290, F1337-F1343.
    View publication on PubMed
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Rattus norvegicus neutral endopeptidase inhibition has natriuretic and aquaretic actions in cirrhosis without any effect on blood pressure and kidney perfusion due to a significant overexpression of thgis enzyme in renal cortex ?
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Organism

Organism UniProt Comment Textmining
Rattus norvegicus
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 adult male Wilstar
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Source Tissue

Source Tissue Comment Organism Textmining
kidney cortex Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
atrial natriuretic peptide + H2O
-
 Rattus norvegicus ?
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 ?
bradykinin + H2O
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 Rattus norvegicus ?
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 ?
additional information neutral endopeptidase inhibition has natriuretic and aquaretic actions in cirrhosis without any effect on blood pressure and kidney perfusion due to a significant overexpression of thgis enzyme in renal cortex Rattus norvegicus ?
-
 ?

Synonyms

Synonyms Comment Organism
neutral endopeptidase
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 Rattus norvegicus