Reference on EC 3.1.3.11 - fructose-bisphosphatase
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Pontremoli, S.; Traniello, S.
Fructose-1,6-diphosphatase and sedoheptulose-1,7-diphosphatase from Candida utilis
Methods Enzymol.
42C
347-353
1975
Cyberlindnera jadinii
Nishizawa, A.N.; Buchanan, B.B.
Enzyme regulation in C4 photosynthesis. Purification and properties of thioredoxin-linked fructose bisphosphatase and sedoheptulose bisphosphatase from corn leaves
J. Biol. Chem.
256
6119-6126
1981
Zea mays
Mizunuma, H.; Tashima, Y.
Mouse thymoma cell line expresses a gluconeogenic enzyme, fructose 1,6-bisphosphatase
Biochem. Biophys. Res. Commun.
158
929-935
1989
Mus musculus
Marcus, F.; Rittenhouse, J.; Moberly, L.; Edelstein, I.; Hiller, E.; Rogers, D.T.
Yeast (Saccharomyces cerevisiae) fructose-1,6-bisphosphatase. Properties of phospho and dephospho forms and of two mutants in which serine 11 has been changed by site-directed mutagenesis
J. Biol. Chem.
263
6058-6062
1988
Saccharomyces cerevisiae
Rogers, D.T.; Hiller, E.; Mitsock, L.; Orr, E.
Characterization of the gene for fructose-1,6-bisphosphatase from Saccharomyces cerevisiae and Schizosaccharomyces pombe. Sequence, protein homology, and expression during growth on glucose
J. Biol. Chem.
263
6051-6057
1988
Saccharomyces cerevisiae, Schizosaccharomyces pombe
Liu, F.; Fromm, H.J.
Purification and characterization of fructose-1,6-bisphosphatase from bovine brain
Arch. Biochem. Biophys.
260
609-615
1988
Bos taurus
Brown, D.; Kershaw, K.A.
Isolation and characterization of two enzymes capable of hydrolyzing fructose-1,6-bisphosphate from the lichen Peltigera rufescens
Plant Physiol.
82
462-467
1986
Peltigera rufescens
Mizunuma, H.; Tashima, Y.
Characterization of rat muscle fructose 1,6-bisphosphatase
J. Biochem.
99
1781-1788
1986
Rattus norvegicus
Van Tonder, A.; Terblanche, S.E.; Oelofsen, W.
Isolation and partial characterization of rat muscle fructose bisphosphatase
Biochim. Biophys. Acta
831
186-191
1985
Rattus norvegicus
Marques, I.A.; Anderson, L.E.
Changing kinetic properties of fructose-1,6-bisphosphatase from pea chloroplasts during photosynthetic induction
Plant Physiol.
77
807-810
1985
Pisum sativum
Ganson, N.J.; Fromm, H.J.
Mechanism and regulation of bovine liver fructose-1,6-bisphosphatase
Curr. Top. Cell. Regul.
24
197-207
1984
Bos taurus
Kruger, N.J.; Beevers, H.
Effect of fructose 2,6-bisphosphate on the kinetic properties of cytoplasmic fructose 1,6-bisphosphatase from germinating castor bean endosperm
Plant Physiol.
76
49-54
1984
Ricinus communis
Toyoda, Y.; Sy, J.
Purification and phosphorylation of fructose-1,6-bisphosphatase from Kluyveromyces fragilis
J. Biol. Chem.
259
8718-8723
1984
Kluyveromyces marxianus
Noda, T.; Hoffschulte, H.; Holzer, H.
Characterization of fructose 1,6-bisphosphatase from bakers yeast
J. Biol. Chem.
259
7191-7197
1984
Saccharomyces cerevisiae
Babul, J.; Guixe, V.
Fructose bisphosphatase from Escherichia coli. Purification and characterization
Arch. Biochem. Biophys.
225
944-949
1983
Escherichia coli
Villeret, V.; Huang, S.; Zhang, Y.; Lipscomb, W.N.
Structural aspects of the allosteric inhibition of fructose-1,6-bisphosphatase by AMP: the binding of both the substrate analogue 2,5-anhydro-D-glucitol 1,6-bisphosphate and catalytic metal ions monitored by X-ray crystallography
Biochemistry
34
4307-4315
1995
Sus scrofa
Attwood, M.M.; VanDijken, J.P.
Characteristics of fructose-1,6-bisphosphatase from the methanol-ultilizing yeast Hansenula polymorpha
J. Gen. Microbiol.
128
2313-2317
1982
Ogataea angusta
-
Opheim, D.J.; Bernlohr, R.W.
Fructose-1,6-bisphosphatase from Bacillus licheniformis
Methods Enzymol.
90
384-391
1982
Bacillus licheniformis, Bacillus licheniformis A5
Springate, C.F.; Stachow, C.S.
Fructose-bisphosphatase from Rhodopseudomonas palustris
Methods Enzymol.
90
378-384
1982
Rhodopseudomonas palustris
Kelly, G.J.; Zimmermann, G.; Latzko, E.
Fructose-bisphosphatase from spinach leaf chloroplast and cytoplasm
Methods Enzymol.
90
371-378
1982
Spinacia oleracea
Storey, K.B.
Fructose-1,6-bisphosphatase from bumblebee flight muscle
Methods Enzymol.
90
366-371
1982
Bombus terrestris
Tashima, Y.; Mizunuma, H.
Fructose-1,6-bisphosphatase from mouse and rabbit intestinal mucosa
Methods Enzymol.
90
357-365
1982
Oryctolagus cuniculus, Mus musculus
Marcus, F.; Rittenhouse, J.; Chatterjee, T.; Hosey, M.M.
Fructose-1,6-bisphosphatase from rat liver
Methods Enzymol.
90
352-357
1982
Rattus norvegicus
Xu, G.J.; Shi, J.P.; Wang, Y.L.
Fructose-1,6-bisphosphatase from snake muscle (Zaocys dhumnades)
Methods Enzymol.
90
349-351
1982
Ptyas dhumnades
Horecker, B.L.; McGregor, W.C.; Traniello, S.; Melloni, E.; Pontremoli, S.
Fructose-1,6-bisphosphatase from rabbit liver (neutral form)
Methods Enzymol.
90
345-348
1982
Oryctolagus cuniculus
MacGregor, J.S.; Annamalai, A.E.; van Tol, A.; Black, W.J.; Horecker, B.L.
Fructose-1,6-bisphosphatase from chicken and rabbit muscle
Methods Enzymol.
90
340-345
1982
Gallus gallus, Oryctolagus cuniculus
Han, P.F.; Johnson, J.
Fructose-1,6-bisphosphatase from turkey liver
Methods Enzymol.
90
334-340
1982
Meleagris gallopavo
Nimmo, H.G.; Tipton, K.F.
Fructose-bisphosphatase from ox liver
Methods Enzymol.
90
330-334
1982
Bos taurus
DeMaine, M.M.; Caperelli, C.A.; Benkovic, S.J.
Fructose-bisphosphatase, zinc-free, from rabbit liver
Methods Enzymol.
90
327-329
1982
Oryctolagus cuniculus
Woodrow, I.E.; Kelly, G.J.; Latzko, E.
Fructosebisphosphatase of plant roots
Z. Pflanzenphysiol.
106
119-127
1982
Pisum sativum, Zea mays
-
Dzugaj, A.; Kochman, M.
Purification of human liver fructose-1,6-bisphosphatase
Biochim. Biophys. Acta
614
407-412
1980
Homo sapiens
Mizunuma, H.; Hasegawa, M.; Tashima, Y.
Properties of rabbit intestinal fructose 1,6-bisphosphatase
Arch. Biochem. Biophys.
201
296-303
1980
Oryctolagus cuniculus
Amachi, T.; Bowien, B.
Characterization of two fructose bisphosphatase isoenzymes from the hydrogen bacterium Nocardia opaca 1b
J. Gen. Microbiol.
113
347-356
1979
Rhodococcus opacus
-
Tashima, Y.; Mizunuma, H.; Hasegawa, M.
Purification and properties of mouse liver fructose 1,6-bisphosphatase
J. Biochem.
86
1089-1099
1979
Mus musculus
Funayama, S.; Molano, J.; Gancedo, C.
Purification and properties of a D-fructose 1,6-bisphosphatase from Saccharomyces cerevisiae
Arch. Biochem. Biophys.
197
170-177
1979
Saccharomyces cerevisiae
Fujita, Y.; Freese, E.
Purification and properties of fructose-1,6-bisphosphatase of Bacillus subtilis
J. Biol. Chem.
254
5340-5349
1979
Bacillus subtilis
Zimmermann, G.; Kelly, G.J.; Latzko, E.
Purification and properties of spinach leaf cytoplasmic fructose-1,6-bisphosphatase
J. Biol. Chem.
253
5952-5956
1978
Spinacia oleracea
Mizunuma, H.; Tashima, Y.
Fructose-1,6-biphosphatase of the small intestine. Purification and comparison with liver and muscle fructose-1,6-bisphosphatases
J. Biochem.
84
327-336
1978
Mus musculus
Storey, K.B.
Purification and properties of fructose diphosphatase from bumblebee flight muscle. Role of the enzyme in control of substrate cycling
Biochim. Biophys. Acta
523
443-453
1978
Bombus terrestris
McPherson, A.; Burkey, D.; Stankiewicz, P.
Crystalline alkaline form fructose-1,6-diphosphatase. A simple purification procedure and preliminary x-ray diffraction analysis
J. Biol. Chem.
252
7031-7034
1977
Meleagris gallopavo
Annamalai, A.E.; Tsolas, O.; Horecker, B.L.
Crystalline fructose 1,6-bisposphatase from chicken breast muscle
Arch. Biochem. Biophys.
183
48-56
1977
Gallus gallus
Tejwani, G.A.; Pedrosa, F.O.; Pontremoli, S.; Horecker, B.L.
The purification of properties of rat liver fructose 1,6-bisphosphatase
Arch. Biochem. Biophys.
177
255-264
1976
Rattus norvegicus
-
Skalecki, K.; Rakus, D.; Wisniewski, J.R.; Kolodziej, J.; Dzugaj, A.
cDNA sequence and kinetic properties of human lung fructose(1,6)bisphosphatase
Arch. Biochem. Biophys.
365
1-9
1999
Homo sapiens (P09467)
Han, P.F.; Murthy, V.V.; Johnson, J.
Chicken liver fructose 1,6-bisphosphatase: purfication and some properties
Arch. Biochem. Biophys.
173
293-300
1976
Gallus gallus
Buchanan, B.B.
Ferredoxin-activated fructose-1,6-diphosphatase system of spinach chloroplasts
Methods Enzymol.
42C
397-405
1975
Spinacia oleracea
-
Mendicino, J.; Abou-Issa, H.; Medicus, R.; Kratowich, N.
Fructose-1,6-bisphosphatase, phosphofructokinase, glycogen synthetase, phosphorylase, and protein kinase from swine kidney
Methods Enzymol.
42C
375-397
1975
Sus scrofa
-
Ulm, E.H.; Pogell, B.M.; DeMaine, M.M.; Libby, C.B.; Benkovic, S.J.
Fructose-1,6-diphosphatase from rabbit liver
Methods Enzymol.
42C
369-374
1975
Oryctolagus cuniculus
-
Geller, A.M.; Byrne, W.L.
Fructose-1,6-diphosphate from bovine liver
Methods Enzymol.
42C
363-368
1975
Bos taurus
Rosen, O.M.
Purification of fructose-1,6-diphosphate from Polysphondylium pallidum
Methods Enzymol.
42C
360-363
1975
Heterostelium pallidum
Pontremoli, S.; Melloni, E.
Fructose-1,6-diphosphatase from rabbit liver
Methods Enzymol.
42C
354-359
1975
Oryctolagus cuniculus
Han, P.F.; Owen, G.S.; Johnson, J.
Purification and properties of fructose 1,6-bisphosphatase from turkey liver
Arch. Biochem. Biophys.
168
171-179
1975
Meleagris gallopavo
Nimmo, H.G.; Tipton, K.F.
The purification of fructose 1,6-diphosphatase from ox liver and its activation by ethylenediaminetetra-acetate
Biochem. J.
145
323-334
1975
Bos taurus
Traniello, S.
Fructose-1,6-diphosphatase from rat liver. Purification and properties
Biochim. Biophys. Acta
341
129-137
1974
Rattus norvegicus
El-Badry, A.M.
Hexosediphosphatase from spinach chloroplasts. Purification, crystallization and some properties
Biochim. Biophys. Acta
333
366-377
1974
Spinacia oleracea
Springgate, C.F.; Stachow, C.S.
Fructose 1,6-diphosphatase from Rhodopseudomonas palustris. I. Purification and properties
Arch. Biochem. Biophys.
152
1-12
1972
Rhodopseudomonas palustris
Tashima, Y.; Tholey, G.; Drummond, G.; Bertrand, H.; Rosenberg, J.S.; Horecker, B.L.
Purification and properties of a rabbit kidney fructose diphosphatase with neutral pH optimum
Arch. Biochem. Biophys.
149
118-126
1972
Oryctolagus cuniculus
Byrne, W.L.; Rajagopalan, G.T.; Griffin, L.D.; Ellis, E.H.; Harris, R.M.; Hochachka, P.; Reid, L.; Geller, A.M.
Bovine hepatic fructose 1,6-diphosphatase: purification and properties
Arch. Biochem. Biophys.
146
118-133
1971
Bos taurus
Hur, Y.; Vasconcelos, A.C.
Spinach cytosolic fructose-1,6-bisphosphatase: I. Its organ-specific and developmental expression characteristics
Mol. Cells
8
138-147
1998
Spinacia oleracea
Casazza, J.P.; Stone, S.R.; Fromm, H.J.
Kinetic studies of bovine liver fructose-1,6-bisphosphatase
J. Biol. Chem.
254
4661-4665
1979
Bos taurus
Caperelli, C.A.; Frey, W.A.; Benkovic, S.J.
Isotope-tapping experiments with rabbit liver fructose bisphosphatase
Biochemistry
17
1699-1704
1978
Oryctolagus cuniculus
Benkovic, S.J.; deMaine, M.M.
Mechanism of action of fructose 1,6-bisphosphatase
Adv. Enzymol. Relat. Areas Mol. Biol.
53
45-82
1981
Bos taurus, Canis lupus familiaris, Gallus gallus, Oryctolagus cuniculus, Ovis aries, Mus musculus, Rattus norvegicus, Phocidae, Sus scrofa
Vargas, A.M.; Sola, M.M.; Bounias, M.
Inhibition by substrate of fructose 1,6-bisphosphatase purified from rat kidney cortex
J. Biol. Chem.
265
15368-15370
1990
Rattus norvegicus
Fisher, W.K.; Thompson, E.P.
Amino acid sequence studies on sheep liver fructose-bisphosphatase. II. The complete sequence
Aust. J. Biol. Sci.
36
235-250
1983
Ovis aries
Marcus, F.; Edelstein, I.; Reardon, I.; Heinrikson, R.L.
Complete amino acid sequence of pig kidney fructose-1,6-bisphosphatase
Proc. Natl. Acad. Sci. USA
79
7161-7165
1982
Sus scrofa
Horecker, B.L.; MacGregor, J.S.; Singh, V.N.; Tsolas, O.; Sun, S.C.; Crivellaro, O.; Pontremoli, S.
Partial amino acid sequence of rabbit liver fructose 1,6-bisphosphatase (FruP2ase, EC 3.1.3.11) and sites of cleavage by proteinases
Enzyme Regul. and Mechanism of Action (Mildner, P. , Ries, B. , eds. )
60
3-14
1980
Oryctolagus cuniculus
-
Lee, S.W.; Man-Ho, C.; Kang, H.C.; Hahn, T.R.
Purification and general properties of pea cytoplasmic fructose-1,6-bisphosphatase
Korean Biochem. J.
27
538-543
1994
Pisum sativum
-
Rodriguez-Suarez, R.J.; Mora-Garcia, S.; Wolosiuk, R.A.
Characterization of cysteine residues involved in the reductive activation and the structural stability of rapeseed (Brassica napus) chloroplast fructose-1,6-bisphosphatase
Biochem. Biophys. Res. Commun.
232
388-393
1997
Brassica napus
Kurbanov, F.T.; Choe, J.; Honzatko, R.B.; Fromm, H.J.
Directed mutations in the poorly defined region of porcine liver fructose-1,6-bisphosphatase significantly affect catalysis and the mechanism of AMP inhibition
J. Biol. Chem.
273
17511-17516
1998
Sus scrofa
Villeret, V.; Huang, S.; Fromm, H.J.; Lipscomb, W.N.
Crystallographic evidence for the action of potassium, thallium, and lithium ions on fructose-1,6-bisphosphatase
Proc. Natl. Acad. Sci. USA
92
8916-8920
1995
Sus scrofa
Iversen, L.F.; Brzozowski, M.; Hastrup, S.; Hubbard, R.; Kastrup, J.S.; Larsen, I.K.; Naerum, L.; Norskov-Lauridsen, L.; Rasmussen, P.B.; Thim, L.; Wiberg, F.C.; Lundgren, K.
Characterization of the allosteric binding pocket of human liver fructose-1,6-bisphosphatase by protein crystallography and inhibitor activity studies
Protein Sci.
6
971-982
1997
Homo sapiens
Skalecki, K.; Mularczyk, W.; Dzugaj, A.
Kinetic properties of D-fructose-1,6-bisphosphate 1-phosphohydrolase isolated from human muscle
Biochem. J.
310
1029-1035
1995
Homo sapiens
Burton, V.A.; Chen, M.; Ong, W.C.; Ling, T.; Fromm, H.J.; Stayton, M.M.
High-level expression of porcine fructose-1,6-bisphosphatase in Escherichia coli: purification and characterization of the enzyme
Biochem. Biophys. Res. Commun.
192
511-517
1993
Sus scrofa
Adams, A.; Redden, C.; Menahem, S.
Characterization of human fructose 1,6-bisphosphatase in control and deficient tissues
J. Inherit. Metab. Dis.
13
829-848
1990
Homo sapiens
Ashton, A.R.
A simple procedure for purifying the major chloroplast fructose-1,6-bisphosphatase from spinach (Spinacia oleracea) and characterization of its stimulation by sub-femtomolar mercuric ions
Arch. Biochem. Biophys.
357
207-224
1998
Spinacia oleracea (P22418), Spinacia oleracea
Tamoi, M.; Ishikawa, T.; Takeda, T.; Shigeoka, S.
Molecular characterization and resistance to hydrogen peroxide of two fructose-1,6-bisphosphatases from Synechococcus PCC 7942
Arch. Biochem. Biophys.
334
27-36
1996
Synechococcus sp.
Prado, F.E.; Lazaro, J.J.; Hermoso, R.; Chueca, A.; Lopez Gorge, J.
Purification and properties of pea (Pisum sativum L.) thioredoxin f, a plant thioredoxin with unique features in the activation of chloroplast fructose-1,6-bisphosphatase
Planta
188
345-353
1992
Pisum sativum, Spinacia oleracea
Hermoso, R.; Lazaro, J.J.; Chueca, A.; Sahrawy, M.; Lopez-Gorge, J.
Purification and binding features of a pea fructose-1,6-bisphosphatase domain involved in the interaction with thioredoxin f
Physiol. Plant.
105
756-762
1999
Pisum sativum
-
Tamoi, M.; Murakami, A.; Takeda, T.; Shigeoka, S.
Acquisition of a new type of fructose-1,6-bisphosphatase with resistance to hydrogen peroxide in cyanobacteria: molecular charactarization of the enzyme from Synechocystis PCC 6803
Biochim. Biophys. Acta
1383
232-244
1998
Anabaena sp., Leptolyngbya boryana, Synechococcus sp., Anabaena sp. 7120
Dziewulska-Szwajkowska, D.; Dzugaj, A.
Regulatory properties of Rana esculenta liver D-fructose-1,6-bisphosphate 1-phosphohydrolase and their comparison with properties of other vertebrate liver isoenzymes
Comp. Biochem. Physiol. B
122
241-251
1999
Pelophylax lessonae
Preiss, J.; Greenberg, E.
Spinach leaf D-fructose 1,6-diphosphate 1-phosphohydrolase (FDPase) EC 3.1.3.11
Methods Enzymol.
23
691-696
1971
Spinacia oleracea
-
Lazaro, J.J.; Chueca, A.; Lopez Gorge, J.; Mayor, F.
Properties of spinach chloroplast fructose-1,6-diphosphatase
Phytochemistry
14
2579-2583
1975
Spinacia oleracea
-
Mazon, M.J.
Regulation of yeast fructose-1,6-bisphosphatase by phosphorylation-dephosphorylation
Curr. Top. Cell. Regul.
27
159-169
1985
Saccharomyces cerevisiae
Han, J.; Lawson, L.; Chu, T.C.; Potter, D.; Han, G.; Han, P.
Modification of catalytic properties of chicken liver fructose 1,6-bisphosphatase by allicin
Biochem. Mol. Biol. Int.
31
1007-1015
1993
Gallus gallus
Van Praag, E.
Kinetic properties of cytosolic fructose 1,6-bisphosphatase from grapefruit. Effect of citrate
Biochem. Mol. Biol. Int.
43
625-631
1997
Citrus x paradisi
Zhang, R.; Villeret, V.; Lipscomb, W.N.; Fromm, H.J.
Kinetics and mechanism of activation and inhibition of porcine liver fructose-1,6-bisphosphatase by monovalent cations
Biochemistry
35
3038-3043
1996
Sus scrofa
Ladror, U.S.; Latshaw, S.P.; Marcus, F.
Spinach cytosolic fructose-1,6-bisphosphatase. Purification, enzyme properties and structural comparison
Eur. J. Biochem.
189
89-94
1990
Spinacia oleracea
Nel, W.; Terblanche, S.E.
Plant fructose-1,6-bisphosphatases: characteristics and properties
Int. J. Biochem.
24
1267-1283
1992
Pisum sativum, Rhodopseudomonas palustris, Spinacia oleracea, Zea mays
Barcia, R.; Villamarin, J.A.; Vazquez-Illanes, M.D.; Ibarguren, I.; Ramos-Martinez, J.I.
Fructose-1,6-bisphosphatase in mantle of the sea mussel Mytilus galloprovincial is Lmk - I. Purification and ion requirements
Comp. Biochem. Physiol. B
100
635-639
1991
Mytilus galloprovincialis
-
Koekemoer, T.C.; Stanton, L.A.; Oelofsen, W.
Kinetic properties of ovine adipose tissue fructose-1,6-bisphosphatase
Comp. Biochem. Physiol. B
109
443-450
1994
Oryctolagus cuniculus, Ovis aries, Homo sapiens, Rattus norvegicus
-
Van Tonder, A.; Naude, R.J.; Oelofsen, W.
Ostrich fructose-1,6-bisphosphatase: kinetic characterization of the liver isoenzyme
Int. J. Biochem.
23
991-995
1991
Struthio camelus
-
Reyes, A.; Rodriguez, P.; Siebe, J.C.
The interaction of monovalent cations with fructose 1,6-bisphosphatase modified by N-ethylmaleimide and its relation with AMP inhibition
Biochem. Int.
26
347-356
1992
Sus scrofa
Shyur, L.F.; Aleshin, A.E.; Honzatko, R.B.; Fromm, H.J.
Biochemical properties of mutant and wild-type fructose-1,6-bisphosphatases are consistent with the coupling of intra- and intersubunit conformational changes in the T- and R-state transition
J. Biol. Chem.
271
33301-33307
1996
Sus scrofa (P00636), Sus scrofa
Shyur, L.F.; Poland, B.W.; Honzatko, R.B.; Fromm, H.J.
Major changes in the kinetic mechanism of AMP inhibition and AMP cooperativity attends the mutation of Arg49 in fructose-1,6-bisphosphatase
J. Biol. Chem.
272
26295-26299
1997
Sus scrofa
Zhu, D.W.; Xu, G.J.; Rehse, P.H.; Shi, R.; Zhao, F.K.; Lin, S.X.
Crystallization and preliminary crystallographic data of fructose-1,6-bisphosphatase from human muscle
Acta Crystallogr. Sect. D
57
847-849
2001
Homo sapiens
Shin, E.H.; Yoo, Y.C.; Lee, S.W.; Hahn, T.R.
Purification and characterization of a recombinant pea chloroplastic fructose-1, 6-bisphosphatase
Agric. Chem. Biotechnol.
44
167-172
2001
Pisum sativum
-
Rittmann, D.; Schaffer, S.; Wendisch, V.F.; Sahm, H.
Fructose-1,6-bisphosphatase from Corynebacterium glutamicum: expression and deletion of the fbp gene and biochemical characterization of the enzyme
Arch. Microbiol.
180
285-292
2003
Corynebacterium glutamicum
Choe, J.Y.; Fromm, H.J.; Honzatko, R.B.
Crystal structures of fructose 1,6-bisphosphatase: mechanism of catalysis and allosteric inhibition revealed in product complexes
Biochemistry
39
8565-8574
2000
Sus scrofa (P00636)
Balmer, Y.; Stritt-Etter, A.L.; Hirasawa, M.; Jacquot, J.P.; Keryer, E.; Knaff, D.B.; Schurmann, P.
Oxidation-reduction and activation properties of chloroplast fructose 1,6-bisphosphatase with mutated regulatory site
Biochemistry
40
15444-15450
2001
Spinacia oleracea
Kelley-Loughnane, N.; Biolsi, S.A.; Gibson, K.M.; Lu, G.; Hehir, M.J.; Phelan, P.; Kantrowitz, E.R.
Purification, kinetic studies, and homology model of Escherichia coli fructose-1,6-bisphosphatase
Biochim. Biophys. Acta
1594
6-16
2002
Escherichia coli, Sus scrofa (P00636), Sus scrofa
Reichert, A.; Dennes, A.; Vetter, S.; Scheibe, R.
Chloroplast fructose 1,6-bisphosphatase with changed redox modulation: comparison of the Galdieria enzyme with cysteine mutants from spinach
Biochim. Biophys. Acta
1645
212-217
2003
Arabidopsis thaliana, Brassica napus, Galdieria sulphuraria (Q95AJ2), Galdieria sulphuraria, Glycine max, Oryza sativa, Pisum sativum, Solanum tuberosum, Spinacia oleracea, Triticum aestivum
Zhang, F.W.; Zhao, F.K.; Xu, G.J.
Molecular cloning, expression and purification of muscle fructose-1,6-bisphosphatase from Zaocys dhumnades: the role of the N-terminal sequence in AMP activation at alkaline pH
Biol. Chem.
381
561-566
2000
Homo sapiens, Rattus norvegicus, Sus scrofa, Ptyas dhumnades
Wright, S.W.; Hageman, D.L.; McClure, L.D.; Carlo, A.A.; Treadway, J.L.; Mathiowetz, A.M.; Withka, J.M.; Bauer, P.H.
Allosteric inhibition of fructose-1,6-bisphosphatase by anilinoquinazolines
Bioorg. Med. Chem. Lett.
11
17-21
2001
Oryctolagus cuniculus, Homo sapiens, Rattus norvegicus
Rakus, D.; Skalecki, K.; Dzugaj, A.
Kinetic properties of pig (Sus scrofa domestica) and bovine (Bos taurus) D-fructose-1,6-bisphosphate 1-phosphohydrolase (F1,6BPase): liver-like isozymes in mammalian lung tissue
Comp. Biochem. Physiol. B
127
123-134
2000
Bos taurus, Oryctolagus cuniculus, Homo sapiens, Sus scrofa domesticus
Gizak, A.; Rakus, D.; Kolodziej, J.; Zabel, M.; Ogorzalek, A.; Dzugaj, A.
Human lung fructose-1,6-bisphosphatase is localized in pneumocytes II
Histol. Histopathol.
16
53-55
2001
Homo sapiens
Gizak, A.; Rakus, D.; Dzugaj, A.
Immunohistochemical localization of human fructose-1,6-bisphosphatase in subcellular structures of myocytes
Histol. Histopathol.
18
135-142
2003
Homo sapiens
Donahue, J.L.; Bownas, J.L.; Niehaus, W.G.; Larson, T.J.
Purification and characterization of glpX-encoded fructose 1, 6-bisphosphatase, a new enzyme of the glycerol 3-phosphate regulon of Escherichia coli
J. Bacteriol.
182
5624-5627
2000
Escherichia coli (P0A9C9), Escherichia coli
Verhees, C.H.; Akerboom, J.; Schiltz, E.; de Vos, W.M.; van der Oost, J.
Molecular and biochemical characterization of a distinct type of fructose-1,6-bisphosphatase from Pyrococcus furiosus
J. Bacteriol.
184
3401-3405
2002
Sus scrofa (P00636), Pyrococcus furiosus (Q8TZH9), Pyrococcus furiosus
Nelson, S.W.; Choe, J.Y.; Honzatko, R.B.; Fromm, H.J.
Mutations in the hinge of a dynamic loop broadly influence functional properties of fructose-1,6-bisphosphatase
J. Biol. Chem.
275
29986-29992
2000
Sus scrofa (P00636), Sus scrofa
Nelson, S.W.; Honzatko, R.B.; Fromm, H.J.
Hybrid tetramers of porcine liver fructose-1,6-bisphosphatase reveal multiple pathways of allosteric inhibition
J. Biol. Chem.
277
15539-15545
2002
Sus scrofa
Rashid, N.; Imanaka, H.; Kanai, T.; Fukui, T.; Atomi, H.; Imanaka, T.
A novel candidate for the true fructose-1,6-bisphosphatase in Archaea
J. Biol. Chem.
277
30649-30655
2002
Thermococcus kodakarensis (Q8NKR9), Thermococcus kodakarensis
Choe, J.Y.; Nelson, S.W.; Arienti, K.L.; Axe, F.U.; Collins, T.L.; Jones, T.K.; Kimmich, R.D.; Newman, M.J.; Norvell, K.; Ripka, W.C.; Romano, S.J.; Short, K.M.; Slee, D.H.; Fromm, H.J.; Honzatko, R.B.
Inhibition of fructose-1,6-bisphosphatase by a new class of allosteric effectors
J. Biol. Chem.
278
51176-51183
2003
Escherichia coli
Reichert, A.; Baalmann, E.; Vetter, S.; Backhausen, J.E.; Scheibe, R.
Activation properties of the redox-modulated chloroplast enzymes glyceraldehyde 3-phosphate dehydrogenase and fructose-1,6-bisphosphatase
Physiol. Plant.
110
330-341
2000
Spinacia oleracea
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Ghosh, S.; Bagchi, S.; Lahiri Majumder, A.
Chloroplast fructose-1,6-bisphosphatase from Oryza differs in salt tolerance property from the Porteresia enzyme and is protected by osmolytes
Plant Sci.
160
1171-1181
2001
Oryza sativa, Oryza coarctata
Obiadalla-Ali, H.; Fernie, A.R.; Lytovchenko, A.; Kossmann, J.; Lloyd, J.R.
Inhibition of chloroplastic fructose 1,6-bisphosphatase in tomato fruits leads to decreased fruit size, but only small changes in carbohydrate metabolism
Planta
219
533-540
2004
Solanum lycopersicum
Tang, G.L.; Wang, Y.F.; Bao, J.S.; Chen, H.B.
Overexpression in Escherichia coli and characterization of the chloroplast fructose-1,6-bisphosphatase from wheat
Protein Expr. Purif.
19
411-418
2000
Triticum aestivum
Jang, H.K.; Lee, S.W.; Lee, Y.H.; Hahn, T.R.
Purification and characterization of a recombinant pea cytoplasmic fructose-1,6-bisphosphatase
Protein Expr. Purif.
28
42-48
2003
Escherichia coli, Spinacia oleracea, Sus scrofa, Pisum sativum (Q8RW99), Pisum sativum
Kelley-Loughnane, N.; Kantrowitz, E.R.
Binding of AMP to two of the four subunits of pig kidney fructose-1,6-bisphosphatase induces the allosteric transition
Proteins Struct. Funct. Genet.
44
255-261
2001
Sus scrofa
Becker, J.; Klopprogge, C.; Zelder, O.; Heinzle, E.; Wittmann, C.
Amplified expression of fructose 1,6-bisphosphatase in Corynebacterium glutamicum increases in vivo flux through the pentose phosphate pathway and lysine production on different carbon sources
Appl. Environ. Microbiol.
71
8587-8596
2005
Corynebacterium glutamicum
Gu, X.; Chen, M.; Shen, H.; Jiang, X.; Huang, Y.; Wang, H.
Rv2131c gene product: an unconventional enzyme that is both inositol monophosphatase and fructose-1,6-bisphosphatase
Biochem. Biophys. Res. Commun.
339
897-904
2006
Mycobacterium tuberculosis
Rakus, D.; Pasek, M.; Krotkiewski, H.; Dzugaj, A.
Interaction between muscle aldolase and muscle fructose 1,6-bisphosphatase results in the substrate channeling
Biochemistry
43
14948-14957
2004
Oryctolagus cuniculus
Wang, Y.K.; Morgan, A.; Stieglitz, K.; Stec, B.; Thompson, B.; Miller, S.J.; Roberts, M.F.
The temperature dependence of the inositol monophosphatase Km correlates with accumulation of di-myo-inositol 1,1'-phosphate in Archaeoglobus fulgidus
Biochemistry
45
3307-3314
2006
Archaeoglobus fulgidus
von Geldern, T.W.; Lai, C.; Gum, R.J.; Daly, M.; Sun, C.; Fry, E.H.; Abad-Zapatero, C.
Benzoxazole benzenesulfonamides are novel allosteric inhibitors of fructose-1,6-bisphosphatase with a distinct binding mode
Bioorg. Med. Chem. Lett.
16
1811-1815
2006
Homo sapiens
Muindi, J.R.; Peng, Y.; Wilson, J.W.; Johnson, C.S.; Branch, R.A.; Trump, D.L.
Monocyte fructose 1,6-bisphosphatase and cytidine deaminase enzyme activities: potential pharmacodynamic measures of calcitriol effects in cancer patients
Cancer Chemother. Pharmacol.
59
97-104
2006
Homo sapiens
Dziewulska-Szwajkowska, D.; Ogorzalek, A.
F-actin, beta-tubulin, aldolase, and fructose-1,6-bisphosphatase in heteropteran ovarioles--I. Immunocytochemical investigations of whole-mounted ovarioles
Cell Tissue Res.
321
311-321
2005
Ilyocoris cimicoides, Coreus marginatus, Lygus pratensis, Notostira elongata
Dziewulska-Szwajkowska, D.; Zmojdzian, M.; Dobryszycki, P.; Kochman, M.; Dzugaj, A.
The interaction of FBPase with aldolase: A kinetic and fluorescence investigation on chicken muscle enzymes
Comp. Biochem. Physiol. B
137B
115-129
2004
Gallus gallus
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Zmojdzian, M.; Dziewulska-Szwajkowska, D.; Dzugaj, A.
Localization of chicken muscle FBPase in cardiomyocyte nuclei
Comp. Biochem. Physiol. B
140
37-43
2005
Gallus gallus (Q9I8D3), Gallus gallus
Adamowicz, A.; Gizak, A.; Dzugaj, A.
Subcellular localization of muscle FBPase in carp (Cyprinus carpio) tissues
Comp. Biochem. Physiol. B
144
223-228
2006
Cyprinus carpio
Gizak, A.; Majkowski, M.; Dus, D.; Dzugaj, A.
Calcium inhibits muscle FBPase and affects its intracellular localization in cardiomyocytes
FEBS Lett.
576
445-448
2004
Oryctolagus cuniculus
Yanez, A.J.; Garcia-Rocha, M.; Bertinat, R.; Droppelmann, C.; Concha, II; Guinovart, J.J.; Slebe, J.C.
Subcellular localization of liver FBPase is modulated by metabolic conditions
FEBS Lett.
577
154-158
2004
Rattus norvegicus
Mamczur, P.; Rakus, D.; Gizak, A.; Dus, D.; Dzugaj, A.
The effect of calcium ions on subcellular localization of aldolase-FBPase complex in skeletal muscle
FEBS Lett.
579
1607-1612
2005
Oryctolagus cuniculus
Rakus, D.; Maciaszczyk, E.; Wawrzycka, D.; Ulaszewski, S.; Eschrich, K.; Dzugaj, A.
The origin of the high sensitivity of muscle fructose 1,6-bisphosphatase towards AMP
FEBS Lett.
579
5577-5581
2005
Homo sapiens (P09467)
Rakus, D.; Gizak, A.; Dzugaj, A.
The regulation of the interaction between F-actin and muscle fructose 1,6-bisphosphatase
Int. J. Biol. Macromol.
35
33-38
2005
Oryctolagus cuniculus
Sato, T.; Imanaka, H.; Rashid, N.; Fukui, T.; Atomi, H.; Imanaka, T.
Genetic evidence identifying the true gluconeogenic fructose-1,6-bisphosphatase in Thermococcus kodakaraensis and other hyperthermophiles
J. Bacteriol.
186
5799-5807
2004
Thermococcus kodakarensis
Nelson, S.W.; Honzatko, R.B.; Fromm, H.J.
Origin of cooperativity in the activation of fructose-1,6-bisphosphatase by Mg2+
J. Biol. Chem.
279
18481-18487
2004
Sus scrofa (P00636), Sus scrofa
Iancu, C.V.; Mukund, S.; Fromm, H.J.; Honzatko, R.B.
R-state AMP complex reveals initial steps of the quaternary transition of fructose-1,6-bisphosphatase
J. Biol. Chem.
280
19737-19745
2005
Escherichia coli
Hines, J.K.; Fromm, H.J.; Honzatko, R.B.
Novel allosteric activation site in Escherichia coli fructose-1,6-bisphosphatase
J. Biol. Chem.
281
18386-18393
2006
Escherichia coli (P0A993), Escherichia coli
Yanez, A.J.; Bertinat, R.; Spichiger, C.; Carcamo, J.G.; de Los Angeles Garcia, M.; Concha, II; Nualart, F.; Slebe, J.C.
Novel expression of liver FBPase in Langerhans islets of human and rat pancreas
J. Cell. Physiol.
205
19-24
2005
Homo sapiens, Rattus norvegicus
Sahrawy, M.; Avila, C.; Chueca, A.; Canovas, F.M.; Lopez-Gorge, J.
Increased sucrose level and altered nitrogen metabolism in Arabidopsis thaliana transgenic plants expressing antisense chloroplastic fructose-1,6-bisphosphatase
J. Exp. Bot.
55
2495-2503
2004
Arabidopsis thaliana
Gizak, A.; Rakus, D.; Dzugaj, A.
Nuclear Localization of fructose 1,6-bisphosphatase in smooth muscle cells
J. Mol. Histol.
36
243-248
2005
Sus scrofa
Cazalis, R.; Chueca, A.; Sahrawy, M.; Lopez-Gorge, J.
Construction of chimeric cytosolic fructose-1,6-bisphosphatases by insertion of a chloroplastic redox regulatory cluster
J. Physiol. Biochem.
60
7-22
2004
Beta vulgaris, Homo sapiens
Georgi, T.; Rittmann, D.; Wendisch, V.F.
Lysine and glutamate production by Corynebacterium glutamicum on glucose, fructose and sucrose: roles of malic enzyme and fructose-1,6-bisphosphatase
Metab. Eng.
7
291-301
2005
Corynebacterium glutamicum
Movahedzadeh, F.; Rison, S.C.; Wheeler, P.R.; Kendall, S.L.; Larson, T.J.; Stoker, N.G.
The Mycobacterium tuberculosis Rv1099c gene encodes a GlpX-like class II fructose 1,6-bisphosphatase
Microbiology
150
3499-3505
2004
Mycobacterium tuberculosis (P9WN21), Mycobacterium tuberculosis, Mycobacterium tuberculosis H37Rv (P9WN21)
Kitanovic, A.; Wolfl, S.
Fructose-1,6-bisphosphatase mediates cellular responses to DNA damage and aging in Saccharomyces cerevisiae
Mutat. Res.
594
135-147
2006
Saccharomyces cerevisiae
Zhou, R.; Cheng, L.
Biochemical characterization of cytosolic fructose-1,6-bisphosphatase from apple (Malus domestica) leaves
Plant Cell Physiol.
45
879-886
2004
Malus domestica
Tamoi, M.; Nagaoka, M.; Miyagawa, Y.; Shigeoka, S.
Contribution of fructose-1,6-bisphosphatase and sedoheptulose-1,7-bisphosphatase to the photosynthetic rate and carbon flow in the calvin cycle in transgenic plants
Plant Cell Physiol.
47
380-390
2006
Synechococcus elongatus PCC 7942 = FACHB-805 (Q59943)
Anderson, L.E.; Yousefzai, R.; Ringenberg, M.R.; Carol, A.A.
Both chloroplastic and cytosolic fructose bisphosphatase isozymes are present in the pea leaf nucleus
Plant Sci.
166
721-730
2004
Pisum sativum
Naderer, T.; Ellis, M.A.; Sernee, M.F.; De Souza, D.P.; Curtis, J.; Handman, E.; McConville, M.J.
Virulence of Leishmania major in macrophages and mice requires the gluconeogenic enzyme fructose-1,6-bisphosphatase
Proc. Natl. Acad. Sci. USA
103
5502-5507
2006
Leishmania major
Nishimasu, H.; Fushinobu, S.; Shoun, H.; Wakagi, T.
The first crystal structure of the novel class of fructose-1,6-bisphosphatase present in thermophilic archaea
Structure
12
949-959
2004
Sulfurisphaera tokodaii, Sulfurisphaera tokodaii 7
Gomez-Milan, E.; Cardenete, G.; Sanchez-Muros, M.J.
Annual variations in the specific activity of fructose 1,6-bisphosphatase, alanine aminotransferase and pyruvate kinase in the Sparus aurata liver
Comp. Biochem. Physiol. B
147B
49-55
2007
Sparus aurata (Q8AYI5)
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Caporaletti, D.; D'Alessio, A.C.; Rodriguez-Suarez, R.J.; Senn, A.M.; Duek, P.D.; Wolosiuk, R.A.
Non-reductive modulation of chloroplast fructose-1,6-bisphosphatase by 2-Cys peroxiredoxin
Biochem. Biophys. Res. Commun.
355
722-727
2007
Brassica napus (P46267)
Rosini, M.; Mancini, F.; Tarozzi, A.; Colizzi, F.; Andrisano, V.; Bolognesi, M.L.; Hrelia, P.; Melchiorre, C.
Design, synthesis, and biological evaluation of substituted 2,3-dihydro-1H-cyclopenta[b]quinolin-9-ylamine related compounds as fructose-1,6-bisphosphatase inhibitors
Bioorg. Med. Chem.
14
7846-7853
2006
Oryctolagus cuniculus
Lai, C.; Gum, R.J.; Daly, M.; Fry, E.H.; Hutchins, C.; Abad-Zapatero, C.; von Geldern, T.W.
Benzoxazole benzenesulfonamides as allosteric inhibitors of fructose-1,6-bisphosphatase
Bioorg. Med. Chem. Lett.
16
1807-1810
2006
Homo sapiens, Rattus norvegicus
Sybirna, N.; Dziewulska-Szwajkowska, D.; Barska, M.; Dzugaj, A.
Mononuclear and polymorphonuclear leukocytes show increased fructose-1,6-bisphosphatase activity in patients with type 1 diabetes mellitus
Cell Biol. Int.
30
624-630
2006
Homo sapiens
van Poelje, P.D.; Dang, Q.; Erion, M.D.
Discovery of fructose-1,6-bisphosphatase inhibitors for the treatment of type 2 diabetes
Curr. Opin. Drug Discov. Devel.
10
430-437
2007
Homo sapiens
van Poelje, P.D.; Potter, S.C.; Chandramouli, V.C.; Landau, B.R.; Dang, Q.; Erion, M.D.
Inhibition of fructose 1,6-bisphosphatase reduces excessive endogenous glucose production and attenuates hyperglycemia in Zucker diabetic fatty rats
Diabetes
55
1747-1754
2006
Rattus norvegicus
Lamont, B.J.; Visinoni, S.; Fam, B.C.; Kebede, M.; Weinrich, B.; Papapostolou, S.; Massinet, H.; Proietto, J.; Favaloro, J.; Andrikopoulos, S.
Expression of human fructose-1,6-bisphosphatase in the liver of transgenic mice results in increased glycerol gluconeogenesis
Endocrinology
147
2764-2772
2006
Homo sapiens
Ludwig, H.C.; Pardo, F.N.; Asenjo, J.L.; Maureira, M.A.; Yanez, A.J.; Slebe, J.C.
Unraveling multistate unfolding of pig kidney fructose-1,6-bisphosphatase using single tryptophan mutants
FEBS J.
274
5337-5349
2007
Sus scrofa (P00636), Sus scrofa
Gizak, A.; Wrobel, E.; Moraczewski, J.; Dzugaj, A.
Changes in subcellular localization of fructose 1,6-bisphosphatase during differentiation of isolated muscle satellite cells
FEBS Lett.
580
4042-4046
2006
Rattus norvegicus
Zarzycki, M.; Maciaszczyk, E.; Dzugaj, A.
Glu 69 is essential for the high sensitivity of muscle fructose-1,6-bisphosphatase inhibition by calcium ions
FEBS Lett.
581
1347-1350
2007
Oryctolagus cuniculus
Erion, M.D.; Dang, Q.; Reddy, M.R.; Kasibhatla, S.R.; Huang, J.; Lipscomb, W.N.; van Poelje, P.D.
Structure-guided design of AMP mimics that inhibit fructose-1,6-bisphosphatase with high affinity and specificity
J. Am. Chem. Soc.
129
15480-15490
2007
Homo sapiens (P09467), Homo sapiens
Dang, Q.; Kasibhatla, S.R.; Reddy, K.R.; Jiang, T.; Reddy, M.R.; Potter, S.C.; Fujitaki, J.M.; van Poelje, P.D.; Huang, J.; Lipscomb, W.N.; Erion, M.D.
Discovery of potent and specific fructose-1,6-bisphosphatase inhibitors and a series of orally-bioavailable phosphoramidase-sensitive prodrugs for the treatment of type 2 diabetes
J. Am. Chem. Soc.
129
15491-15502
2007
Homo sapiens, Rattus norvegicus
Dougherty, M.J.; Boyd, J.M.; Downs, D.M.
Inhibition of fructose-1,6-bisphosphatase by aminoimidazole carboxamide ribotide prevents growth of Salmonella enterica purH mutants on glycerol
J. Biol. Chem.
281
33892-33899
2006
Salmonella enterica
Hines, J.K.; Fromm, H.J.; Honzatko, R.B.
Structures of activated fructose-1,6-bisphosphatase from Escherichia coli. Coordinate regulation of bacterial metabolism and the conservation of the R-state
J. Biol. Chem.
282
11696-11704
2007
Escherichia coli (P0A993), Escherichia coli
Hines, J.K.; Kruesel, C.E.; Fromm, H.J.; Honzatko, R.B.
Structure of inhibited fructose-1,6-bisphosphatase from Escherichia coli: distinct allosteric inhibition sites for AMP and glucose 6-phosphate and the characterization of a gluconeogenic switch
J. Biol. Chem.
282
24697-24706
2007
Escherichia coli (P0A993), Escherichia coli
Hines, J.K.; Chen, X.; Nix, J.C.; Fromm, H.J.; Honzatko, R.B.
Structures of mammalian and bacterial fructose-1,6-bisphosphatase reveal the basis for synergism in AMP/fructose 2,6-bisphosphate inhibition
J. Biol. Chem.
282
36121-36131
2007
Sus scrofa (P00636), Sus scrofa, Escherichia coli (P0A993), Escherichia coli
Yanez, A.J.; Bustamante, X.; Bertinat, R.; Werner, E.; Rauch, M.C.; Concha, I.I.; Reyes, J.G.; Slebe, J.C.
Expression of key substrate cycle enzymes in rat spermatogenic cells: fructose 1,6 bisphosphatase and 6 phosphofructose 1-kinase
J. Cell. Physiol.
212
807-816
2007
Rattus norvegicus
Mutyala, R.; Reddy, R.N.; Sumakanth, M.; Reddanna, P.; Reddy, M.R.
Calculation of relative binding affinities of fructose 1,6-bisphosphatase mutants with adenosine monophosphate using free energy perturbation method
J. Comput. Chem.
28
932-937
2007
Homo sapiens
Gizak, A.; Maciaszczyk, E.; Dzugaj, A.; Eschrich, K.; Rakus, D.
Evolutionary conserved N-terminal region of human muscle fructose 1,6-bisphosphatase regulates its activity and the interaction with aldolase
Proteins
72
209-216
2008
Homo sapiens
Qi, S.W.; Chaudhry, M.T.; Zhang, Y.; Meng, B.; Huang, Y.; Zhao, K.X.; Poetsch, A.; Jiang, C.Y.; Liu, S.; Liu, S.J.
Comparative proteomes of Corynebacterium glutamicum grown on aromatic compounds revealed novel proteins involved in aromatic degradation and a clear link between aromatic catabolism and gluconeogenesis via fructose-1,6-bisphosphatase
Proteomics
7
3775-3787
2007
Corynebacterium glutamicum
Anderson, L.E.; Gibbons, J.T.
Effect of leaf position on levels of the chloroplast and cytosolic fructose bisphosphatase isozymes in the pea leaf nucleus
Protoplasma
231
113-121
2007
Pisum sativum
Visinoni, S.; Fam, B.C.; Blair, A.; Rantzau, C.; Lamont, B.J.; Bouwman, R.; Watt, M.J.; Proietto, J.; Favaloro, J.M.; Andrikopoulos, S.
Increased glucose production in mice overexpressing human fructose-1,6-bisphosphatase in the liver
Am. J. Physiol. Endocrinol. Metab.
295
E1132-E1141
2008
Homo sapiens
Bigl, M.; Jandrig, B.; Horn, L.C.; Eschrich, K.
Aberrant methylation of human L- and M-fructose 1,6-bisphosphatase genes in cancer
Biochem. Biophys. Res. Commun.
377
720-724
2008
Homo sapiens
Kepka, A.; Dariusz Szajda, S.; Stypu?kowska, A.; Waszkiewicz, N.; Jankowska, A.; Chojnowska, S.; Zwierz, K.
Urinary fructose-1,6-bisphosphatase activity as a marker of the damage to the renal proximal tubules in children with idiopathic nephrotic syndrome
Clin. Chem. Lab. Med.
46
831-835
2008
Homo sapiens
Kebede, M.; Favaloro, J.; Gunton, J.E.; Laybutt, D.R.; Shaw, M.; Wong, N.; Fam, B.C.; Aston-Mourney, K.; Rantzau, C.; Zulli, A.; Proietto, J.; Andrikopoulos, S.
Fructose-1,6-bisphosphatase overexpression in pancreatic beta-cells results in reduced insulin secretion: a new mechanism for fat-induced impairment of beta-cell function
Diabetes
57
1887-1895
2008
Homo sapiens
Jardon, R.; Gancedo, C.; Flores, C.L.
The gluconeogenic enzyme fructose-1,6-bisphosphatase is dispensable for growth of the yeast Yarrowia lipolytica in gluconeogenic substrates
Eukaryot. Cell
7
1742-1749
2008
Yarrowia lipolytica (Q7Z8Q0), Yarrowia lipolytica
Yoshida, T.; Okuno, A.; Izumi, M.; Takahashi, K.; Hagisawa, Y.; Ohsumi, J.; Fujiwara, T.
CS-917, a fructose 1,6-bisphosphatase inhibitor, improves postprandial hyperglycemia after meal loading in non-obese type 2 diabetic Goto-Kakizaki rats
Eur. J. Pharmacol.
601
192-197
2008
Rattus norvegicus
Jang, H.; Cho, M.; Kwon, Y.; Bhoo, S.H.; Jeon, J.; Hahn, T.
Roles of the residues Lys115 and Tyr116 in the binding of an allosteric inhibitor AMP to pea cytosolic D-fructose-1,6-bisphosphatase
J. Appl. Biol. Chem.
51
45-49
2008
Pisum sativum
-
Brown, C.R.; Wolfe, A.B.; Cui, D.; Chiang, H.L.
The vacuolar import and degradation pathway merges with the endocytic pathway to deliver fructose-1,6-bisphosphatase to the vacuole for degradation
J. Biol. Chem.
283
26116-26127
2008
Saccharomyces cerevisiae (P09201)
Brown, G.; Singer, A.; Lunin, V.V.; Proudfoot, M.; Skarina, T.; Flick, R.; Kochinyan, S.; Sanishvili, R.; Joachimiak, A.; Edwards, A.M.; Savchenko, A.; Yakunin, A.F.
Structural and biochemical characterization of the type II D-fructose-1,6-bisphosphatase GlpX from Escherichia coli
J. Biol. Chem.
284
3784-3792
2009
Escherichia coli (P0A9C9), Escherichia coli (P21437), Escherichia coli
Dang, Q.; Kasibhatla, S.R.; Jiang, T.; Fan, K.; Liu, Y.; Taplin, F.; Schulz, W.; Cashion, D.K.; Reddy, K.R.; van Poelje, P.D.; Fujitaki, J.M.; Potter, S.C.; Erion, M.D.
Discovery of phosphonic diamide prodrugs and their use for the oral delivery of a series of fructose 1,6-bisphosphatase inhibitors
J. Med. Chem.
51
4331-4339
2008
Homo sapiens, Rattus norvegicus
Rudnitskaya, A.; Huynh, K.; Toeroek, B.; Stieglitz, K.
Novel heteroaromatic organofluorine inhibitors of fructose-1,6-bisphosphatase
J. Med. Chem.
52
878-882
2009
Mus musculus
Nadas, E.; Balogh, A.; Kiss, F.; Szente, K.; Nagy, Z.; Martinez-Carrasco, R.; Tuba, Z.
Role of fructose-1,6-bisphosphatase, fructose phosphotransferase, and phosphofructokinase in saccharide metabolism of four C3 grassland species under elevated CO2
Photosynthetica
46
255-261
2008
Dactylis glomerata, Filipendula vulgaris, Festuca rupicola, Salvia nemorosa
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