Literature summary for 3.1.3.11 extracted from

Movahedzadeh, F.; Rison, S.C.; Wheeler, P.R.; Kendall, S.L.; Larson, T.J.; Stoker, N.G.
The Mycobacterium tuberculosis Rv1099c gene encodes a GlpX-like class II fructose 1,6-bisphosphatase (2004), Microbiology, 150, 3499-3505.

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Inhibitors

Inhibitors	Comment	Organism	Structure
Li+	50% inhibition at 1.1 mM	Mycobacterium tuberculosis
additional information	phosphoenolpyruvate, AMP, ADP, citrate, not inhibitory up to 1 mM	Mycobacterium tuberculosis

KM Value [mM]

KM Value [mM]	KM Value Maximum [mM]	Substrate	Comment	Organism	Structure
0.015	-	D-fructose 1,6-bisphosphate	37°C	Mycobacterium tuberculosis

Organism

Organism	UniProt	Comment	Textmining
Mycobacterium tuberculosis	P9WN21	product of Rv1099c gene	-
Mycobacterium tuberculosis H37Rv	P9WN21	product of Rv1099c gene	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
D-fructose 1,6-bisphosphate + H2O	-	Mycobacterium tuberculosis	D-fructose 6-phosphate + phosphate	-	?
D-fructose 1,6-bisphosphate + H2O	-	Mycobacterium tuberculosis H37Rv	D-fructose 6-phosphate + phosphate	-	?

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Release 2023.1 (January 2023)