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BRENDA support

Information on EC 2.3.1.43 - phosphatidylcholine-sterol O-acyltransferase

for references in articles please use BRENDA:EC2.3.1.43

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IUBMB Comments

Palmitoyl, oleoyl and linoleoyl residues can be transferred; a number of sterols, including cholesterol, can act as acceptors. The bacterial enzyme also catalyses the reactions of EC 3.1.1.4 phospholipase A2 and EC 3.1.1.5 lysophospholipase.

The expected taxonomic range for this enzyme is: Bacteria, Eukaryota

Synonyms
lecithin:cholesterol acyltransferase, lecithin-cholesterol acyltransferase, lecithin cholesterol acyltransferase, lecithin cholesterol acyl transferase, lecithin-cholesterol acyl transferase, plasma lecithin-cholesterol acyltransferase, lecithin/cholesterol acyltransferase, lecithin:cholesterol acyl-transferase, tglcat, phospholipid-cholesterol acyltransferase, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
phosphatidylcholine + a sterol = 1-acylglycerophosphocholine + a sterol ester
show the reaction diagram
PATHWAY SOURCE
PATHWAYS