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Literature summary for 2.3.1.43 extracted from
- Stereochemical substrate requirements of lecithin:cholesterol acyltransferase and its inhibition by enantiomeric lysolecithins (1980), Can. J. Biochem., 58, 1286-1291.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| lysophosphatidylcholine | both enantiomers, inhibition reversed by albumin | Homo sapiens |  |
| Triton X-100 | inhibition reversed by albumin | Homo sapiens | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 2-sn-phosphorylcholinediacylglycerol + cholesterol | lower activity than the natural substrate | Homo sapiens | ? | - |
? | |
| additional information | no significant activity with 1-sn-phosphorylcholinediacylglycerol | Homo sapiens | ? | - |
? | |
| phosphatidylcholine + sterol | - |
Homo sapiens | 1-acylglycerophosphocholine + sterol ester | - |
r | |
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Release 2023.1 (January 2023)
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