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3.4.23.34: cathepsin E

This is an abbreviated version!
For detailed information about cathepsin E, go to the full flat file.

Word Map on EC 3.4.23.34

Reaction

similar to cathepsin D, but slightly broader specificity =

Synonyms

CatE, Cathepsin D-like acid proteinase, cathepsin D-like aspartic proteinase, cathepsin D-like protease, Cathepsin D-type proteinase, cathepsin E, Cathepsin E-like acid proteinase, CE, CTSE, EMAP, erythrocyte membrane acid proteinase, Erythrocyte membrane aspartic proteinase, gastric mucosa non-pepsin acid proteinase, More, Non-pepsin proteinase, slow moving proteinase, Slow-moving proteinase, SMP

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.23 Aspartic endopeptidases
                3.4.23.34 cathepsin E

Purification

Purification on EC 3.4.23.34 - cathepsin E

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PURIFICATION (Commentary)
ORGANISM
UNIPROT
LITERATURE
2 catalytically active forms CE-I and CE-II
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2 isozymes
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affinity chromatography
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as procathepsin E
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as procathepsin E from spleen
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as procathepsin E with following activation by lowering the pH-value of the solution to 4
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DEAE-Sephacel chromatography and immunodepletion
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gastric enzyme
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immunoaffinity chromatography
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monomeric form
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recombinant
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recombinant from heterologous Chinese hamster ovary cells (3 forms: cytosolic s-CE and vacuolar v-CE-1 and 2)
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recombinant from Pichia pastoris
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wild-type and T284S and D98E mutant proteins
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