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3.4.23.34: cathepsin E

This is an abbreviated version!
For detailed information about cathepsin E, go to the full flat file.

Word Map on EC 3.4.23.34

Reaction

similar to cathepsin D, but slightly broader specificity =

Synonyms

CatE, Cathepsin D-like acid proteinase, cathepsin D-like aspartic proteinase, cathepsin D-like protease, Cathepsin D-type proteinase, cathepsin E, Cathepsin E-like acid proteinase, CE, CTSE, EMAP, erythrocyte membrane acid proteinase, Erythrocyte membrane aspartic proteinase, gastric mucosa non-pepsin acid proteinase, More, Non-pepsin proteinase, slow moving proteinase, Slow-moving proteinase, SMP

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.23 Aspartic endopeptidases
                3.4.23.34 cathepsin E

pH Range

pH Range on EC 3.4.23.34 - cathepsin E

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pH RANGE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
1 - 4
-
83% of maximal activity at pH 1 and 55% of maximal activity at pH 4, hemoglobin as substrate
1.6 - 3.9
-
half-maximal activity at pH 1.6 and 3.9, hemoglobin as substrate
2 - 4
-
90% of maximal activity at pH 2 and half-maximal activity at pH 4, hemoglobin as substrate
2 - 5
-
pH 2.0 and 5.0: approximately 80% of maximal activity
3.5 - 4.8
-
pH 3.5.-4.5: optimum, pH 4.8: about 25% of maximal activity
5 - 7
-
active in the presence of ATP
5.8
-
and above, no activity in the absence of ATP
additional information