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3.4.23.34: cathepsin E

This is an abbreviated version!
For detailed information about cathepsin E, go to the full flat file.

Word Map on EC 3.4.23.34

Reaction

similar to cathepsin D, but slightly broader specificity =

Synonyms

CatE, Cathepsin D-like acid proteinase, cathepsin D-like aspartic proteinase, cathepsin D-like protease, Cathepsin D-type proteinase, cathepsin E, Cathepsin E-like acid proteinase, CE, CTSE, EMAP, erythrocyte membrane acid proteinase, Erythrocyte membrane aspartic proteinase, gastric mucosa non-pepsin acid proteinase, More, Non-pepsin proteinase, slow moving proteinase, Slow-moving proteinase, SMP

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.23 Aspartic endopeptidases
                3.4.23.34 cathepsin E

Turnover Number

Turnover Number on EC 3.4.23.34 - cathepsin E

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TURNOVER NUMBER [1/s]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
1.55 - 11.9
(7-methoxycoumarin-4-yl)-acetyl-Gly-Lys-Pro-Ile-Ile-Phe-Phe-Arg-Leu-Lys(2,4-dinitrophenyl)-D-Arg-NH2
39.1
(7-methoxycoumarin-4-yl)acetyl-Gly-Lys-Pro-Ile-Ile-Phe-Phe-Arg-Leu-Lys(Dnp)-D-Arg-NH2
-
40°C, pH 4.0, gastric cathepsin E
32.2
(7-methoxycoumarin-4-yl)acetyl-Gly-Lys-Pro-Ile-Leu-Phe-Phe-Arg-Leu-Lys(Dnp)-D-Arg-NH2
-
40°C, pH 4.0, wild-type cathepsin E
0.52 - 20.1
(7-methoxycoumarin-4-yl)acetyl-Gly-Ser-Pro-Ala-Phe-Leu-Ala-Lys(Dnp)-D-Arg-NH2
1.68
(7-methoxycoumarin-4-yl)acetyl-Gly-Ser-Ser-Ala-Phe-Leu-Ala-Phe-Lys(Dnp)-D-Arg-NH2
-
40°C, pH 4.0, gastric cathepsin E
322.5
(7-methoxycoumarin-4-yl)acetyl-L-Ala-Gly-L-Phe-L-Ser-L-Leu-L-Pro-L-Ala-L-Lys(Dnp)-D-Arg-amide
-
pH 4.0, 27°C
26
Acetyl-substance P
-
pH 5
19
Acetyl-substance P(2-11)
-
pH 5
58
Acetyl-substance P(3-11)
-
pH 5
18
acidic fibroblast growth factor
-
pH 5
-
64
Arg-modified substance P
-
pH 5
-
0.13
big ET-1
0.1
big ET-2
-
-
0.14
big ET-3
-
-
10
Eledoisin
-
pH 5
135
Lys-Pro-Ala-Glu-Phe-(4-nitro)Phe-Arg-Leu
-
pH 3.1
26 - 170
Lys-Pro-Ile-Glu-Phe-(4-nitro)Phe-Arg-Leu
360
MOCAc-Gly-Lys-Pro-Ile-Leu-Phe-Phe-Arg-Leu-Lys(Dnp)-D-Arg-NH2
-
25°C, pH 4.0
42
Neurokinin A
-
pH 5
13
Porcine renin substrate
-
pH 5
5 - 132
Pro-Pro-Thr-Ile-Phe-(4-nitro)Phe-Arg-Leu
27
Pro-Thr-Glu-Phe-(4-nitro)Phe-Arg-Leu
-
pH 3.1
22
Substance P(2-11)
-
pH 5
70
Substance P(3-11)
-
pH 5
0.74
Substance P(4-11)
-
pH 5
23
[His10]-substance P
-
pH 5
40
[Tyr8]-substance P
-
pH 5
additional information
additional information
-