3.4.23.34: cathepsin E
This is an abbreviated version!
For detailed information about cathepsin E, go to the full flat file.
Word Map on EC 3.4.23.34
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3.4.23.34
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cathepsins
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proteinases
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pepstatin
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pepsinogen
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procathepsin
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molecular biology
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gastricsin
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medicine
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foveolar
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non-lysosomal
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3.4.23.5
- 3.4.23.34
- cathepsins
- proteinases
- pepstatin
- pepsinogen
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procathepsin
- molecular biology
- gastricsin
- medicine
-
foveolar
-
non-lysosomal
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3.4.23.5
Reaction
similar to cathepsin D, but slightly broader specificity =
Synonyms
CatE, Cathepsin D-like acid proteinase, cathepsin D-like aspartic proteinase, cathepsin D-like protease, Cathepsin D-type proteinase, cathepsin E, Cathepsin E-like acid proteinase, CE, CTSE, EMAP, erythrocyte membrane acid proteinase, Erythrocyte membrane aspartic proteinase, gastric mucosa non-pepsin acid proteinase, More, Non-pepsin proteinase, slow moving proteinase, Slow-moving proteinase, SMP
ECTree
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Turnover Number
Turnover Number on EC 3.4.23.34 - cathepsin E
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1.55 - 11.9
(7-methoxycoumarin-4-yl)-acetyl-Gly-Lys-Pro-Ile-Ile-Phe-Phe-Arg-Leu-Lys(2,4-dinitrophenyl)-D-Arg-NH2
39.1
(7-methoxycoumarin-4-yl)acetyl-Gly-Lys-Pro-Ile-Ile-Phe-Phe-Arg-Leu-Lys(Dnp)-D-Arg-NH2
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40°C, pH 4.0, gastric cathepsin E
32.2
(7-methoxycoumarin-4-yl)acetyl-Gly-Lys-Pro-Ile-Leu-Phe-Phe-Arg-Leu-Lys(Dnp)-D-Arg-NH2
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40°C, pH 4.0, wild-type cathepsin E
1.68
(7-methoxycoumarin-4-yl)acetyl-Gly-Ser-Ser-Ala-Phe-Leu-Ala-Phe-Lys(Dnp)-D-Arg-NH2
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40°C, pH 4.0, gastric cathepsin E
322.5
(7-methoxycoumarin-4-yl)acetyl-L-Ala-Gly-L-Phe-L-Ser-L-Leu-L-Pro-L-Ala-L-Lys(Dnp)-D-Arg-amide
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pH 4.0, 27°C
1.55
(7-methoxycoumarin-4-yl)-acetyl-Gly-Lys-Pro-Ile-Ile-Phe-Phe-Arg-Leu-Lys(2,4-dinitrophenyl)-D-Arg-NH2
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pH 3.5, 40°C, mutant D98E
6.4
(7-methoxycoumarin-4-yl)-acetyl-Gly-Lys-Pro-Ile-Ile-Phe-Phe-Arg-Leu-Lys(2,4-dinitrophenyl)-D-Arg-NH2
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pH 3.5, 40°C, mutant T284S
11.9
(7-methoxycoumarin-4-yl)-acetyl-Gly-Lys-Pro-Ile-Ile-Phe-Phe-Arg-Leu-Lys(2,4-dinitrophenyl)-D-Arg-NH2
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pH 3.5, 40°C, wild-type
0.52
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40°C, pH 4.0, wild-type cathepsin E
13.58
(7-methoxycoumarin-4-yl)acetyl-Gly-Ser-Pro-Ala-Phe-Leu-Ala-Lys(Dnp)-D-Arg-NH2
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40°C, pH 4.0, wild-type cathepsin E
18.8
(7-methoxycoumarin-4-yl)acetyl-Gly-Ser-Pro-Ala-Phe-Leu-Ala-Lys(Dnp)-D-Arg-NH2
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40°C, pH 4.0, erythrocyte cathepsin E
19.4
(7-methoxycoumarin-4-yl)acetyl-Gly-Ser-Pro-Ala-Phe-Leu-Ala-Lys(Dnp)-D-Arg-NH2
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40°C, pH 4.0, erythrocyte cathepsin E
20.1
(7-methoxycoumarin-4-yl)acetyl-Gly-Ser-Pro-Ala-Phe-Leu-Ala-Lys(Dnp)-D-Arg-NH2
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40°C, pH 4.0, gastric cathepsin E
82
Lys-Pro-Ile-Glu-Phe-(4-nitro)Phe-Arg-Leu
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Cys4-Ala mutant cathepsin E, pH 3.1
11
Pro-Pro-Thr-Ile-Phe-(4-nitro)Phe-Arg-Leu
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with ATP, pH 6.6 and without ATP, pH 5
70
Pro-Pro-Thr-Ile-Phe-(4-nitro)Phe-Arg-Leu
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Cys4-Ala mutant cathepsin E, pH 3.1
additional information
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pH-dependence of kinetic constants
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additional information
additional information
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pH-dependence of kinetic constants
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additional information
additional information
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pH-dependence of kinetic constants
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