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3.4.22.60: caspase-7

This is an abbreviated version!
For detailed information about caspase-7, go to the full flat file.

Word Map on EC 3.4.22.60

Reaction

strict requirement for an Asp residue at position P1 and has a preferred cleavage sequence of Asp-Glu-Val-Asp-/- =

Synonyms

apoptotic protease Mch-3, C14.004, Casp-7, Casp7, caspase 7, caspase-7, CMH-1, cystein aspartic-specific protease-7, DEVDase, ICE-LAP3, ICE-like apoptotic protease 3, LICE2 cysteine protease, More, SCA-2, SREBP cleavage activity 2

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.22 Cysteine endopeptidases
                3.4.22.60 caspase-7

KI Value

KI Value on EC 3.4.22.60 - caspase-7

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Ki VALUE [mM]
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
5.5
2-[(2-acetylphenyl)sulfanyl]benzoic acid
pH not specified in the publication, temperature not specified in the publication
0.000425
acetyl-AEVD-aldehyde
-
pH 7.5, 25°C
0.133
acetyl-Ala-Pro-Nle-Asp-aldehyde
-
pH 7.5
0.0000016 - 0.000035
acetyl-DEVD-aldehyde
0.00328
acetyl-IETD-aldehyde
-
pH 7.5, 25°C
0.126
benzyloxycarbonyl-Pro-Nle-Asp-aldehyde
-
pH 7.5, 25°C
0.0000018
DEVD-aldehyde
pH 7.5, 37°C
0.0044
N-acetyl-Trp-Glu-His-Asp-CHO
-
-
0.0124
N-acetyl-Tyr-Val-Ala-Asp-CHO
-
-
0.667
[2-(phenylsulfanyl)phenyl]acetic acid
pH not specified in the publication, temperature not specified in the publication