Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

3.4.22.60: caspase-7

This is an abbreviated version!
For detailed information about caspase-7, go to the full flat file.

Word Map on EC 3.4.22.60

Reaction

strict requirement for an Asp residue at position P1 and has a preferred cleavage sequence of Asp-Glu-Val-Asp-/- =

Synonyms

apoptotic protease Mch-3, C14.004, Casp-7, Casp7, caspase 7, caspase-7, CMH-1, cystein aspartic-specific protease-7, DEVDase, ICE-LAP3, ICE-like apoptotic protease 3, LICE2 cysteine protease, More, SCA-2, SREBP cleavage activity 2

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.22 Cysteine endopeptidases
                3.4.22.60 caspase-7

Crystallization

Crystallization on EC 3.4.22.60 - caspase-7

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
CRYSTALLIZATION (Commentary)
ORGANISM
UNIPROT
LITERATURE
2.9 A crystal structure of recombinant C285A procaspase, sitting drop vapor diffusion method
hanging drop method, crystal structures of caspase-7 are determined in complexes with six peptide analogs (acetyl-DMQD-CHO, acetyl-DQMD-CHO, acetyl-DNLD-CHO, acetyl-IEPD-CHO, acetyl-ESMD-CHO, acetyl-WEHD-CHO)
-
hanging drop vapor diffusion method
-
in complex with inhibitor 2-[(2-acetylphenyl)sulfanyl]benzoic acid