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3.4.22.60: caspase-7

This is an abbreviated version!
For detailed information about caspase-7, go to the full flat file.

Word Map on EC 3.4.22.60

Reaction

strict requirement for an Asp residue at position P1 and has a preferred cleavage sequence of Asp-Glu-Val-Asp-/- =

Synonyms

apoptotic protease Mch-3, C14.004, Casp-7, Casp7, caspase 7, caspase-7, CMH-1, cystein aspartic-specific protease-7, DEVDase, ICE-LAP3, ICE-like apoptotic protease 3, LICE2 cysteine protease, More, SCA-2, SREBP cleavage activity 2

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.22 Cysteine endopeptidases
                3.4.22.60 caspase-7

Expression

Expression on EC 3.4.22.60 - caspase-7

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EXPRESSION
ORGANISM
UNIPROT
LITERATURE
challenging with Aeromonas hydrophila induces apoptosis in the blood and kidney and results in the significant upregulation of Casp-7 expression. Expression is also upregulated in the kidney leukocytes following in vitro stimulation with lipopolysaccharide and inactivated Aeromonas hydrophila
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