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3.4.17.1: carboxypeptidase A

This is an abbreviated version!
For detailed information about carboxypeptidase A, go to the full flat file.

Word Map on EC 3.4.17.1

Reaction

release of a C-terminal amino acid, but little or no action with -Asp, -Glu, -Arg, -Lys or -Pro =

Synonyms

A-type metallocarboxypeptidase, AcCP, Anson's enzyme, ASPA, aspartoacyclase, carboxypeptidase, carboxypeptidase a, carboxypeptidase A-6, carboxypeptidase A-like activity, carboxypeptidase A1, carboxypeptidase A2, Carboxypeptidase A3, carboxypeptidase A4, carboxypeptidase vitellogenic-like, carboxypeptidase-A, carboxypolypeptidase, colon mast cell carboxypeptidase, CPA, CPA1, CPA3, CPA4, CPA6, CPAI, CPD, CPVL, EC 3.4.12.2, EC 3.4.2.1, hCPA, hCPA4, mast cell carboxypeptidase A, mast cell CPA, mast cell-CPA, mast-cell carboxypeptidase A, mast-cell CPA, MC-CP, MC-CPA, MCCPA, MCP-2, mCPA, MDCP-A1, MDCP-A2, MeCPA, MF-CPA, molting carboxypeptidase A, molting fluid carboxypeptidase A, More, Nna1/CCP1, ochratoxin A hydrolytic enzyme, PTD012, RMC-CP, vitellogenic-like carboxypeptidase

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.17 Metallocarboxypeptidases
                3.4.17.1 carboxypeptidase A

Source Tissue

Source Tissue on EC 3.4.17.1 - carboxypeptidase A

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SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SOURCE
-
liver cancer cell line, high expression level
Manually annotated by BRENDA team
during molting periods
Manually annotated by BRENDA team
-
low expression level
Manually annotated by BRENDA team
low expression levels in cingulate cortex, lateral septum, pontine nucleus, and inferior olivary nucleus
Manually annotated by BRENDA team
low expression level
Manually annotated by BRENDA team
low expression level
Manually annotated by BRENDA team
-
in primary macrophages, CPVL is glycosylated with high mannose residues
Manually annotated by BRENDA team
-
CPVL is up-regulated during the maturation of monocytes to macrophages. Expression in monocyte-derived dendritic cells
Manually annotated by BRENDA team
-
vaginal mucosa
Manually annotated by BRENDA team
-
PC-3m human prostate cancer cell line
Manually annotated by BRENDA team
low CPA6 expression level
Manually annotated by BRENDA team
-
antigen A33-prositive colon carcinoma cell line
Manually annotated by BRENDA team
-
expressed in phorbol myristate acetate-stimulated cells
Manually annotated by BRENDA team
the enzyme expression is induced during pupal ecdysis
Manually annotated by BRENDA team
additional information