3.4.17.1: carboxypeptidase A

This is an abbreviated version!
For detailed information about carboxypeptidase A, go to the full flat file.

Word Map on EC 3.4.17.1

3.4.17.1

agonist

cerebellopontine

cyclophosphamide

cyclopiazonic

nerve

artery

cyproterone

pulmonary

n6-cyclopentyladenosine

cryoprotective

cryopreservation

resect

postoperative

hearing

facial

sarcoplasmic

cranial

aspergillosis

vestibular

schwannomas

aversion

auditory

meningioma

ca2+-atpase

dpcpx

cardiopulmonary

preoperative

acoustic

antiandrogenic

vitrification

fossa

resuscitation

rantes

ryanodine

ca2+-free

craniotomy

epidermoids

chymase

serca

hirsutism

neuralgia

post-thawing

lipoma

2-chloroadenosine

tinnitus

radiosurgery

vertigo

mip-1beta

hemifacial

pharmacology

drug development

out-of-hospital

biotechnology

medicine

analysis

synthesis

food industry

Reaction

release of a C-terminal amino acid, but little or no action with -Asp, -Glu, -Arg, -Lys or -Pro =

Synonyms

A-type metallocarboxypeptidase, AcCP, Anson's enzyme, ASPA, aspartoacyclase, carboxypeptidase, carboxypeptidase a, carboxypeptidase A-6, carboxypeptidase A-like activity, carboxypeptidase A1, carboxypeptidase A2, Carboxypeptidase A3, carboxypeptidase A4, carboxypeptidase vitellogenic-like, carboxypeptidase-A, carboxypolypeptidase, colon mast cell carboxypeptidase, CPA, CPA1, CPA3, CPA4, CPA6, CPAI, CPD, CPVL, EC 3.4.12.2, EC 3.4.2.1, hCPA, hCPA4, mast cell carboxypeptidase A, mast cell CPA, mast cell-CPA, mast-cell carboxypeptidase A, mast-cell CPA, MC-CP, MC-CPA, MCCPA, MCP-2, mCPA, MDCP-A1, MDCP-A2, MeCPA, MF-CPA, molting carboxypeptidase A, molting fluid carboxypeptidase A, More, Nna1/CCP1, ochratoxin A hydrolytic enzyme, PTD012, RMC-CP, vitellogenic-like carboxypeptidase

ECTree

3 Hydrolases

3.4 Acting on peptide bonds (peptidases)

3.4.17 Metallocarboxypeptidases

3.4.17.1 carboxypeptidase A

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Results	in table
20	Activating Compound
121	AA Sequence
32	Application
2	CAS Registry Number
30	Cloned(Commentary)
31	Crystallization (Commentary)
6802	Disease/ Diagnostics
8	Expression
4	General Information
9	General Stability
8	IC50 Value
325	Inhibitors
12	kcat/KM [mM/s]
177	Ki Value [mM]
105	KM Value [mM]
28	Localization
87	Metals/Ions
58	Molecular Weight [Da]
15	Natural Substrates/ Products (Substrates)
172	Organism
62	PDB ID
53	pH Optimum
13	pH Range
9	pH Stability
15	pI Value
9	Posttranslational Modification
40	Protein Variants
37	Purification (Commentary)
27	Reaction
27	Reaction Type
168	Reference
2	Renatured (Commentary)
168	Source Tissue
36	Specific Activity [micromol/min/mg]
9	Storage Stability
232	Substrates and Products (Substrate)
25	Subunits
156	Synonyms
35	Temperature Optimum [°C]
1	Temperature Range [°C]
12	Temperature Stability [°C]
90	Turnover Number [1/s]

Natural Substrates Products

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of the Enzyme Summary Page.

Natural Substrates Products on EC 3.4.17.1 - carboxypeptidase A

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angiotensin I + H2O

Homo sapiens

706874

apolipoprotein B + H2O

endothelin-1 + H2O

hippuryl-L-phenylalanine + H2O

kinetensin + H2O

methotrexate-phenylalanine + H2O

methotrexate + phenylalanine

Homo sapiens

prodrug activation in SW122 cells

neuromedin N + H2O

neurotensin + H2O

peptidyl-L-amino acid + H2O

Bos taurus

rapid release: Tyr, Phe, Trp, Leu, Ile, Thr, Gln, His, Ala, Val, homoserine, slow release: Asn, Ser, Lys, MetSO2, very slow release: Gly, Asp, Glu, CysSO3, S-carboxymethylcysteine, not released: Pro, hydroxyproline, Arg, enzyme generally releases C-terminal amino acids, with the exception of C-terminal arginine, lysine and proline

36318

sarafotoxin 6b + H2O

Homo sapiens

706874

snake venom toxin + H2O

Homo sapiens

706874

vasoconstrictive factor endothelin 1 + H2O

xenopsin + H2O

additional information

3 entries