3.4.17.1: carboxypeptidase A

This is an abbreviated version!
For detailed information about carboxypeptidase A, go to the full flat file.

Word Map on EC 3.4.17.1

3.4.17.1

agonist

cerebellopontine

cyclophosphamide

cyclopiazonic

nerve

artery

cyproterone

pulmonary

n6-cyclopentyladenosine

cryoprotective

cryopreservation

resect

postoperative

hearing

facial

sarcoplasmic

cranial

aspergillosis

vestibular

schwannomas

aversion

auditory

meningioma

ca2+-atpase

dpcpx

cardiopulmonary

preoperative

acoustic

antiandrogenic

vitrification

fossa

resuscitation

rantes

ryanodine

ca2+-free

craniotomy

epidermoids

chymase

serca

hirsutism

neuralgia

post-thawing

lipoma

2-chloroadenosine

tinnitus

radiosurgery

vertigo

mip-1beta

hemifacial

pharmacology

drug development

out-of-hospital

biotechnology

medicine

analysis

synthesis

food industry

Reaction

release of a C-terminal amino acid, but little or no action with -Asp, -Glu, -Arg, -Lys or -Pro =

Synonyms

A-type metallocarboxypeptidase, AcCP, Anson's enzyme, ASPA, aspartoacyclase, carboxypeptidase, carboxypeptidase a, carboxypeptidase A-6, carboxypeptidase A-like activity, carboxypeptidase A1, carboxypeptidase A2, Carboxypeptidase A3, carboxypeptidase A4, carboxypeptidase vitellogenic-like, carboxypeptidase-A, carboxypolypeptidase, colon mast cell carboxypeptidase, CPA, CPA1, CPA3, CPA4, CPA6, CPAI, CPD, CPVL, EC 3.4.12.2, EC 3.4.2.1, hCPA, hCPA4, mast cell carboxypeptidase A, mast cell CPA, mast cell-CPA, mast-cell carboxypeptidase A, mast-cell CPA, MC-CP, MC-CPA, MCCPA, MCP-2, mCPA, MDCP-A1, MDCP-A2, MeCPA, MF-CPA, molting carboxypeptidase A, molting fluid carboxypeptidase A, More, Nna1/CCP1, ochratoxin A hydrolytic enzyme, PTD012, RMC-CP, vitellogenic-like carboxypeptidase

ECTree

3 Hydrolases

3.4 Acting on peptide bonds (peptidases)

3.4.17 Metallocarboxypeptidases

3.4.17.1 carboxypeptidase A

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Results	in table
20	Activating Compound
121	AA Sequence
32	Application
2	CAS Registry Number
30	Cloned(Commentary)
31	Crystallization (Commentary)
6802	Disease/ Diagnostics
8	Expression
4	General Information
9	General Stability
8	IC50 Value
325	Inhibitors
12	kcat/KM [mM/s]
177	Ki Value [mM]
105	KM Value [mM]
28	Localization
87	Metals/Ions
58	Molecular Weight [Da]
15	Natural Substrates/ Products (Substrates)
172	Organism
62	PDB ID
53	pH Optimum
13	pH Range
9	pH Stability
15	pI Value
9	Posttranslational Modification
40	Protein Variants
37	Purification (Commentary)
27	Reaction
27	Reaction Type
168	Reference
2	Renatured (Commentary)
168	Source Tissue
36	Specific Activity [micromol/min/mg]
9	Storage Stability
232	Substrates and Products (Substrate)
25	Subunits
156	Synonyms
35	Temperature Optimum [°C]
1	Temperature Range [°C]
12	Temperature Stability [°C]
90	Turnover Number [1/s]

Specific Activity

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Specific Activity on EC 3.4.17.1 - carboxypeptidase A

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0.0064

Cosmopolites sordidus

gut extract

668430

0.09

Aspergillus niger

carboxypeptidase A, pH 5.6

683283

10.8

Aspergillus niger

carboxypeptidase A, pH 8.5

108

11.7

recombinant enzyme secreted from Pichia pastoris, cell-free supernatant

14.4

culture filtrate

17.24

2.8

33.5

35.8

purification step Macro-Prep High Q

42.5

59.8

7.2

purified recombinant enzyme, substrate hippuryl-L-phenylalanine

7.54

8.9

850

purified recombinant enzyme, substrate hippuryl-L-phenyllactate

667298

9.2

Aspergillus niger

Aspergillus niger extract, pH 8.5

683283

additional information

16 entries