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1.1.1.205: IMP dehydrogenase
This is an abbreviated version, for detailed information about IMP dehydrogenase, go to the full flat file.
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Synonyms
A1S_3321, BTH_I2056, class I IMPDH, class II IMPDH, dehydrogenase, inosinate, DR63_268, EC 1.2.1.14, GBAA_0008, guaB, guaB2, IMD2, IMD3, IMD4, IMP dehydrogenase, IMP DH, IMP oxidoreductase, IMP-DH, IMP:NAD oxidoreductase, IMP:NAD+ oxidoreductase, IMPD, IMPDH, IMPDH II, IMPDH-1, IMPDH-B, IMPDH-S, IMPDH1, IMPDH2, IMPDHab, IMPDHba, IMPDHbt, IMPDHI, IMPDHII, IMPDHkp, IMPDHlpp, IMPDHnm, IMPDHpa, inosinate dehydrogenase, inosine 5' monophosphate dehydrogenase, inosine 5'-monophosphate dehydrogenase, inosine 5'-monophosphate dehydrogenase 2, inosine 5'-phosphate dehydrogenase, inosine 5-monophosphate dehydrogenase, inosine 5-monophosphate dehydrogenase type I, inosine 5’ -monophosphate dehydrogenase, inosine 5’-monophosphate dehydrogenase 2, inosine monophosphate dehydrogenase, inosine monophosphate oxidoreductase, inosine-5'-monophosphate dehydrogenase, inosine-5'-phosphate dehydrogenase, inosinic acid 5’-monophosphate dehydrogenase, inosinic acid dehydrogenase, lpg1723, mpaF, NMC1103, Raspberry protein, Rv3411c, SOI12, Superoxide-inducible protein 12, type 1 inosine monophosphate, type 2 inosine monophosphate dehydrogenase
ECTree
1.1.1.205 IMP dehydrogenaseAdvanced search results
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in table
28
17735
85
256
850
297
244
11
23
74
260
Source Tissue
Source Tissue on EC 1.1.1.205 - IMP dehydrogenase
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SOURCE TISSUE 
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
SOURCE
additional information
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type II isoform predominates in proliferating cells and is upregulated in neoplastic cells
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from healthy adults and paediatric patients on thiopurine therapy; from healthy adults and paediatric patients on thiopurine therapy
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isoform IMPDH1 undergoes alternate splicing to produce at least two retinal isoforms. The abundance of isoforms differs between the species
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isoform IMPDH1 undergoes alternate splicing to produce at least two retinal isoforms. The abundance of isoforms differs between the species
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isoform IMPDH1 undergoes alternate splicing to produce at least two retinal isoforms. The abundance of isoforms differs between the species
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isoform IMPDH1 undergoes alternate splicing to produce at least two retinal isoforms. The abundance of isoforms differs between the species
inosine monophosphate dehydrogenase is present in all immature cells throughout the retina during embryonic and neonatal development. Following eye opening and cell differentiation, its distribution is restricted to the photoreceptors and bipolar cell, becoming prominent in Muller cells with ageing. Type I enzyme does not play a role in early retinal development but type Igamma has greater activity after postnatal day 10. All forms of type I show an increased propensity to form intracellular macrostructures compared to type II
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isoform IMPDH1 undergoes alternate splicing to produce at least two retinal isoforms. The abundance of isoforms differs between the species
Information
