Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Mycophenolic acid | mixed type inhibition | Mus musculus | |
Sesquiterpene lactones | a class of anti-neoplastic drugs, overview | Mus musculus | |
xanthosine 5'-phosphate | competitive inhibition | Mus musculus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.012 | - |
IMP | - |
Mus musculus | |
0.025 | - |
NAD+ | - |
Mus musculus |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
56000 | - |
SDS-PAGE | Mus musculus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
P-388 lymphocytic leucemia tumor cells | Mus musculus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
P-388 cell | - |
Mus musculus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.236 | - |
- |
Mus musculus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
inosine 5'-phosphate + NAD+ + H2O | - |
Mus musculus | xanthosine 5'-phosphate + NADH | - |
? |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NAD+ | - |
Mus musculus |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.000002 | - |
Mycophenolic acid | for the competitive component | Mus musculus | |
0.000008 | - |
Mycophenolic acid | for the non-competitive component | Mus musculus |