Reference on EC 1.1.1.205 - IMP dehydrogenase

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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Wilson, K.; Collart, F.R.; Huberman, E.; Stringer, J.R.; Ullman, B.
Amplification and molecular cloning of the IMP dehydrogenase gene of Leishmania donovani
J. Biol. Chem.
266
1665-1671
1991
Leishmania donovani, Leishmania donovani MPA100
Manually annotated by BRENDA team
Collart, F.R.; Huberman, E.
Cloning and sequence analysis of the human and Chinese hamster inosine-5-monophosphate dehydrogenase cDNAs
J. Biol. Chem.
263
15769-15772
1988
Cricetulus griseus, Homo sapiens
Manually annotated by BRENDA team
Miyagawa, K.; Kimura, H.; Nakahama, K.; Kikuchi, M.; Doi, M.; Akiyama, S.; Nakao, Y.
Cloning of the Bacillus subtilis IMP dehydrogenase gene and its application to increased production of guanosine
Bio/Technology
4
225-228
1986
Bacillus subtilis, Bacillus subtilis NA7821
-
Manually annotated by BRENDA team
Kanzaki, N.; Miyagawa, K.
Nucleotide sequence of the Bacillus subtilis IMP dehydrogenase gene
Nucleic Acids Res.
18
6710
1990
Bacillus subtilis
Manually annotated by BRENDA team
Hampton, A.; Nomura, A.
Inosine 5-phosphate dehydrogenase. Site of inhibition by guanosine 5-phosphate and of inactivation by 6-chloro- and 6-mercaptopurine ribonucleoside 5-phosphates
Biochemistry
6
679-689
1967
Enterobacter aerogenes
Manually annotated by BRENDA team
Lambden, P.R.; Drabble, W.T.
Inosine 5-monophosphate dehydrogenase of Escherichia coli K12: the nature of the inhibition by guanosine 5-monophosphate
Biochem. J.
133
607-608
1973
Escherichia coli
Manually annotated by BRENDA team
Kuttan, R.; Robins, R.K.; Saunders, P.P.
Inhibition of inosinate dehydrogenase by metabolites of 2-beta-D-ribofuranosyl thiazole-4-carboxamide
Biochem. Biophys. Res. Commun.
107
862-868
1982
Cricetulus griseus
Manually annotated by BRENDA team
Cooney, D.A.; Jayaram, H.N.; Glazer, R.I.; Kelley, J.A.; Marquez, V.E.; Gebeyehu, G.; Van Cott, A.C.; Zwelling, L.A.; Johns, D.G.
Studies on the mechanism of action of tiazofurin metabolism to an analog of NAD with potent IMP dehydrogenase-inhibitory activity
Adv. Enzyme Regul.
21
271-303
1983
Escherichia coli
Manually annotated by BRENDA team
Lui, M.S.; Faderan, M.A.; Liepnieks, J.J.; Natsumeda, Y.; Olah, E.; Jayaram, H.N.; Weber, G.
Modulation of IMP dehydrogenase activity and guanylate metabolism by tiazofurin (2-beta-D-ribofuranosylthiazole-4-carboxamide)
J. Biol. Chem.
259
5078-5082
1984
Homo sapiens
Manually annotated by BRENDA team
Hupe, D.J.; Azzolina, B.A.; Behrens, N.D.
IMP dehydrogenase from the intracellular parasitic protozoan Eimeria tenella and its inhibition by mycophenolic acid
J. Biol. Chem.
261
8363-8369
1986
Eimeria tenella
Manually annotated by BRENDA team
Page, J.D.; Chaney, S.G.; Hall, I.H.; Lee, K.H.; Holbrook, D.J.
Inhibition of inosine monophosphate dehydrogenase by sesquiterpene lactones
Biochim. Biophys. Acta
926
186-194
1987
Mus musculus
Manually annotated by BRENDA team
Yamada, Y.; Natsumeda, Y.; Weber, G.
Action of the active metabolites of tiazofurin and ribavirin on purified IMP dehydrogenase
Biochemistry
27
2193-2196
1988
Rattus norvegicus
Manually annotated by BRENDA team
Weber, G.; Yamaji, Y.; Olah, E.; Natsumeda, Y.; Jayaram, H.N.; Lapis, E.; Zhen, W.; Prajda, N.; Hoffman, R.; Tricot, G.J.
Clinical and molecular impact of inhibition of IMP dehydrogenase activity by tiazofurin
Adv. Enzyme Regul.
28
335-356
1989
Homo sapiens, Rattus norvegicus
Manually annotated by BRENDA team
Robins, R.K.; Revankar, G.R.; McKernan, P.A.; Murray, B.K.; Kirsi, J.J.; North, J.A.
The importance of IMP dehydrogenase inhibition in the broad spectrum antiviral activity of ribavirin and selenazofurin
Adv. Enzyme Regul.
24
29-43
1985
Chlorocebus aethiops, Parainfluenza virus, Vaccinia virus, Vaccinia virus Elstree
Manually annotated by BRENDA team
Yamada, Y.; Goto, H.; Yoshino, M.; Ogasawara, N.
IMP dehydrogenase and action of antimetabolites in human cultured blast cells
Biochim. Biophys. Acta
1051
209-214
1990
Homo sapiens
Manually annotated by BRENDA team
Cooney, D.; Hamel, E.; Cohen, M.; Kang, G.J.; Dalal, M.; Marquez, V.
A simple method for the rapid determination of the stereospecificity of NAD-dependent dehydrogenases applied to mammalian IMP dehydrogenase and bacterial NADH peroxidase
Biochim. Biophys. Acta
916
89-93
1987
Escherichia coli, Mus musculus
Manually annotated by BRENDA team
Nichol, A.W.; Nomura, A.; Hampton, A.
Studies on phosphate binding sites of inosinic acid dehydrogenase and adenylosuccinate synthetase
Biochemistry
6
1008-1015
1967
Enterobacter aerogenes
Manually annotated by BRENDA team
Buzzee, D.H.; Levin, A.P.
Demonstration of an effector site for the enzyme inosine 5-phosphate dehydrogenase
Biochem. Biophys. Res. Commun.
30
673-677
1968
Salmonella enterica subsp. enterica serovar Typhimurium
Manually annotated by BRENDA team
Ishii, K.; Shiio, I.
Regulation of purine ribonucleotide synthesis by end product inhibition. I. Effect of purine nucleotides on inosine-5-phosphate dehydrogenase, xanthosine-5-phosphate aminase and adenylosuccinate lyase of Bacillus subtilis
J. Biochem.
63
661-669
1968
Bacillus subtilis, Bacillus subtilis M
Manually annotated by BRENDA team
Brox, L.W.; Hampton, A.
Inosine 5-phosphate dehydrogenase. Kinetic mechanism and evidence for selective reaction of the 6-chloro analog of inosine 5-phosphate with a cysteine residue at the inosine 5-phosphate site
Biochemistry
7
2589-2596
1968
Enterobacter aerogenes
Manually annotated by BRENDA team
Heyde, E.; Nagabhushanam, A.; Vonarx, M.; Morrison, J.F.
Studies on inosine monophosphate dehydrogenase. Steady state kinetics
Biochim. Biophys. Acta
429
645-660
1976
Enterobacter aerogenes
Manually annotated by BRENDA team
Heyde, E.; Morrison, J.F.
Studies on inosine monophosphate dehydrogenase. Isotope exchange at equilibrium
Biochim. Biophys. Acta
429
661-671
1976
Enterobacter aerogenes
Manually annotated by BRENDA team
Brox, L.W.; Hampton, A.
Inosine-5-phosphate dehydrogenase of Aerobacter aerogenes. Studies of tertiary structure
Biochim. Biophys. Acta
206
215-223
1970
Enterobacter aerogenes
Manually annotated by BRENDA team
Nagata, K.; Mitsui, A.; Tsushima, K.
Intracellular localization of inosine-5-phosphate dehydrogenase in chicken liver
Biochim. Biophys. Acta
177
680-682
1969
Gallus gallus
Manually annotated by BRENDA team
Hampton, A.; Brox, L.W.; Bayer, M.
Analogs of inosine 5-phosphate with phosphorus-nitrogen and phosphorus-sulfur bonds. Binding and kinetic studies with inosine 5-phosphate dehydrogenase
Biochemistry
8
2303-2311
1969
Enterobacter aerogenes
Manually annotated by BRENDA team
Gilbert, H.J.; Drabble, W.T.
Active-site modification of native and mutant forms of inosine 5-monophosphate dehydrogenase from Escherichia coli K12
Biochem. J.
191
533-541
1980
Escherichia coli
Manually annotated by BRENDA team
Pourquie, J.
Regulation of the biosynthesis of purine nucleotides in Schizosaccharomyces pombe. II. Kinetic studies of IMP dehydrogenase
Biochim. Biophys. Acta
185
310-315
1969
Schizosaccharomyces pombe
Manually annotated by BRENDA team
Holmes, E.W.; Pehlke, D.M.; Kelley, W.N.
Human IMP dehydrogenase. Kinetics and regulatory properties
Biochim. Biophys. Acta
364
209-217
1974
Homo sapiens
Manually annotated by BRENDA team
Jackson, R.C.; Weber, G.
IMP dehydrogenase, an enzyme linked with proliferation and malignancy
Nature
256
331-333
1975
Rattus norvegicus
Manually annotated by BRENDA team
Shelp, B.J.; Atkin, C.A.
Role of inosine monophosphate oxidoreductase in the formation of ureides in nitrogen-fixing nodules of Cowpea (Vigna unguiculata L. Walp.)
Plant Physiol.
72
1029-1034
1983
Vigna unguiculata
Manually annotated by BRENDA team
Powell, G.F.
Subunit structure of inosinic acid dehydrogenase from Escherichia coli
Biochemistry
12
1592-1595
1973
Escherichia coli
Manually annotated by BRENDA team
Heyde, E.; Morrison, J.F.
Studies on inosine monophosphate dehydrogenase. An associating-dissociating system
Biochim. Biophys. Acta
429
635-644
1976
Enterobacter aerogenes
Manually annotated by BRENDA team
Atkins, C.A.; Shelp, B.J.; Storer, P.J.
Purification and properties of inosine monophosphate oxidoreductase from nitrogen-fixing nodules of cowpea (Vigna unguiculata L. Walp)
Arch. Biochem. Biophys.
236
807-814
1985
Vigna unguiculata
Manually annotated by BRENDA team
Okada, M.; Shimura, K.; Shiraki, H.; Nakagawa, H.
IMP dehydrogenase. II. Purification and properties of the enzyme from Yoshida sarcoma ascites tumor cells
J. Biochem.
94
1605-1613
1983
Rattus norvegicus
Manually annotated by BRENDA team
Lowe, C.R.; Hans, M.; Spibey, N.; Drabble, W.T.
The purification of inosine 5-monophosphate dehydrogenase from Escherichia coli by affinity chromatography on immobilized Procion dyes
Anal. Biochem.
104
23-28
1980
Escherichia coli
Manually annotated by BRENDA team
Gilbert, H.J.; Lowe, C.R.; Drabble, W.T.
Inosine 5-monophosphate dehydrogenase of Escherichia coli. Purification by affinity chromatography, subunit structure and inhibition by guanosine 5-monophosphate
Biochem. J.
183
481-494
1979
Escherichia coli
Manually annotated by BRENDA team
Jackson, R.C.; Morris, H.P.; Weber, G.
Partial purification, properties and regulation of inosine 5-phosphate dehydrogenase in normal and malignant rat tissues
Biochem. J.
166
1-10
1977
Rattus norvegicus
Manually annotated by BRENDA team
Krishnaiah, K.V.
Inosinic acid 5-monophosphate dehydrogenase of Escherichia coli: purification by affinity chromatography and some properties
Arch. Biochem. Biophys.
170
567-575
1975
Escherichia coli
Manually annotated by BRENDA team
Yokosawa, H.; Tobita, T.; Yamada, T.
Studies on inosine-5-phosphate dehydrogenase of Bacillus subtilis. Purification and general properties
Biochim. Biophys. Acta
227
538-553
1971
Bacillus subtilis
Manually annotated by BRENDA team
Turner, J.F.; King, J.E.
Inosine 5'-phosphate dehydrogenase of pea seeds
Biochem. J.
79
147-151
1961
Pisum sativum
Manually annotated by BRENDA team
Magasanik, B.; Moyed, H.S.; Gehring, L.B.
Enzymes essential for the biosynthesis of nucleic acid guanine; inosine 5'-phosphate dehydrogenase of Aerobacter aerogenes
J. Biol. Chem.
226
339-350
1957
Enterobacter aerogenes
Manually annotated by BRENDA team
Anderson, J.H.; Sartorelli, A.C.
Inosinic acid dehydrogenase of sarcoma 180 cells
J. Biol. Chem.
243
4762-4768
1968
Mus musculus
Manually annotated by BRENDA team
Powell, G.; Rajagopalan, K.V.; Handler, P.
Rajagopalan KV, Handler P: Purification and properties of inosinic acid dehydrogenase from Escherichia coli
J. Biol. Chem.
244
4793-4797
1969
Escherichia coli
Manually annotated by BRENDA team
Pugh, M.E.; Skibo, E.B.
Inosine monophosphate dehydrogenase from porcine (Sus scrofa domestica) thymus: Purification and properties
Comp. Biochem. Physiol. B
2
381-387
1993
Sus scrofa
Manually annotated by BRENDA team
Hager, P.W.; Collafrt, F.R.; Huberman, E.; Bitchell, B.S.
Recombinant human inosine monophosphate dehydrogenase type I and type II proteins
Biochem. Pharmacol.
49
1323-1329
1995
Homo sapiens
Manually annotated by BRENDA team
Beck, J.T.; Zhao, S.; Wang, C.C.
Cloning, swquencing, and structural analysis of the DNA encoding inosine monophosphate dehydrogenase (EC 1.1.1.205) from Tritrichomonas foetus
Exp. Parasitol.
78
101-112
1994
Tritrichomonas suis
Manually annotated by BRENDA team
Nelson, P.H.; Carr, S.F.; Devens, B.H.; Eugui, E.M.; Franco, F.; Gonzalez, C.; Hawley, R.C.; Loughhead, D.G.; Milan, D.J.; Papp, E.; Patterson, J.W.; Rouhafza, S.; Sjogren, E.B.; Smith, D.B.; Stephenson, R.A.; Talamas, F.X.; Wastos, A.M.; Weikert, R.J.;
Structure-activity relationships for inhibition of inosine monophosphate dehydrogenase by nuclear variants of mycophenolic acid
J. Med. Chem.
39
4181-4196
1996
Homo sapiens
Manually annotated by BRENDA team
Xiang,B.; Taylor, J.C.; Markham, G.D.
Monovalent cation activation and kinetic mechanism of inosine 5'-monophosphate dehydrogenase
J. Biol. Chem.
271
1435-1440
1996
Homo sapiens
Manually annotated by BRENDA team
Griesmacher, A.; Weigel, G.; Seebacher, G.; Muller, M.M.
IMP-dehydrogenase inhibition in human lymphocytes and lymphoblasts by mycophenolic acid and mycophenolic acid glucuronide
Clin. Chem.
43
2312-2317
1997
Homo sapiens
Manually annotated by BRENDA team
Farazi, t.; Leichman, J.; Harris, T.; Cahoon, M.; Hedstrom, L.
Isolation and characterization onf mycophenolic acid-resistant mutants of inosine-5'-monophosphate dehydrogenase
J. Biol. Chem.
272
961-965
1997
Homo sapiens
Manually annotated by BRENDA team
Bruzzese, F.J.; Connelley, P.R.
Allosteric properties of inosine monophosphate dehydrogenase revealed through the thermodynamics of binding of inosine 5'-monophosphate and mycophenolic acid. Temperature dependent heat capacity of binding as a signature of ligand-coupled conformational equilibria
Biochemistry
36
10428-10438
1997
Cricetulus griseus
Manually annotated by BRENDA team
Zhou, X.; Cahoon, M.; Rosa, P.; Hedstrom, L.
Expression, purification, and characterization of inosine 5'-monophosphate dehydrogenase from Borrelia burgdorferi
J. Biol. Chem.
35
21977-21981
1997
Borreliella burgdorferi
Manually annotated by BRENDA team
Carr, S.F.; Papp, E.; Wu, J.C.; Natsumeda, Y.
Characterization of human type I and type II IMP dehydrogenases
J. Biol. Chem.
36
27286-27290
1993
Homo sapiens
Manually annotated by BRENDA team
O'Gara, M.J.; Lee, C.H.; Weinberg, G.A.; Nott, J.M.; Queener, S.F.
IMP dehydrogenase from Pneumocystis carinii as a potential drug target
Antimicrob. Agents Chemother.
41
40-48
1997
Pneumocystis carinii
Manually annotated by BRENDA team
Miyamoto, T.; Mtsuno, K.; Kim S.I.; Honjoh, K.I.; Hatano, S.
Purification and some properties of IMP dehydrogenase of Bacillus cereus
Microbiol. Res.
153
23-27
1998
Bacillus cereus
Manually annotated by BRENDA team
Zhang, R.G.; Evans, G.; Rotella, F.J.; Westbrook, E.M.; Beno, D.; Huberman, E; Joachimiak, A.; Collart, F.R.
Characteristics and crystal structure of bacterial inosine-5'-monophosphate dehydrogenase
Biochemistry
38
4691-4700
1999
Streptococcus pyogenes (P0C0H6), Streptococcus pyogenes
Manually annotated by BRENDA team
Goldstein, B.M.; Colby, T.D.
IMP dehydrogenase: Structural aspects of inhibitor binding
Curr. Med. Chem.
6
519-536
1999
Borreliella burgdorferi, Cricetulus griseus, Homo sapiens, Streptococcus pyogenes, Tritrichomonas suis
Manually annotated by BRENDA team
Hedstrom, L.
IMP dehydrogenase: Mechanism of action and inhibition
Curr. Med. Chem.
6
545-560
1999
Borreliella burgdorferi, Eimeria tenella, Escherichia coli, Homo sapiens, Rattus norvegicus, Tritrichomonas suis
Manually annotated by BRENDA team
Digits J.A.; Hedstrom L.
Species-specific inhibition of inosine 5'-monophosphate dehydrogenase by mycophenolic acid
Biochemistry
38
15388-15397
1999
Homo sapiens, Tritrichomonas suis
Manually annotated by BRENDA team
Kim, S.I.; Miyamoto, T.; Jonjoh, K.I.; Hatano, S.
Molecular cloning, overproduction and characterization of the Bacillus cereus IMP dehydrogenase
Biosci. Biotechnol. Biochem.
64
1210-1216
2000
Bacillus cereus
Manually annotated by BRENDA team
Barnes, B.J.; Eakin, A.E.; Izydore, R.A.; Hall, I.H.
Implications of selective type II IMP dehydrogenase (IPDH) inhibition by the 6-ethoxycarbonyl-3,3-disubstituted-1,5-diazabicyclo[3.1.0.]hexane-2,4-diones on tumor cell death
Biochem. Pharmacol.
62
91-100
2001
Homo sapiens
Manually annotated by BRENDA team
Albrecht,W.; Storck, M.; Pretsch, E.; Martin, W.; Abendroth, D.
Development and application of a hight-performance liquid chromatography-based assay for determination of the activity of inosine 5'-monophosphate dehydrogenase in whole blood and isolated mononuclear cells
Ther. Drug Monit.
22
283-294
2000
Homo sapiens
Manually annotated by BRENDA team
Colby, T.D.; Vanderveen, K.; Strickler, M.D.; Markham, G.D.; Goldstein, B.M.
Crystal structure of human type II inosine monophosphate dehydrogenase: Implications for ligand binding and drug design
Proc. Natl. Acad. Sci. USA
30
3531-3536
1999
Homo sapiens, Homo sapiens (P12268)
Manually annotated by BRENDA team
Sullivan, W.J.; Dixon, S.E.; Li, C.; Striepen, B.; Queener, S.F.
IMP dehydrogenase from the protozoan parasite Toxoplasma gondii
Antimicrob. Agents Chemother.
49
2172-2179
2005
Toxoplasma gondii (Q4VRV8), Toxoplasma gondii
Manually annotated by BRENDA team
McLean, J.E.; Hamaguchi, N.; Belenky, P.; Mortimer, S.E.; Stanton, M.; Hedstrom, L.
Inosine 5'-monophosphate dehydrogenase binds nucleic acids in vitro and in vivo
Biochem. J.
379
243-251
2004
Escherichia coli, Homo sapiens, Tritrichomonas suis
Manually annotated by BRENDA team
Mortimer, S.E.; Hedstrom, L.
Autosomal dominant retinitis pigmentosa mutations in inosine 5-monophosphate dehydrogenase type I disrupt nucleic acid binding
Biochem. J.
390
41-47
2005
Homo sapiens (P20839)
Manually annotated by BRENDA team
Gan, L.; Petsko, G.A.; Hedstrom, L.
Crystal structure of a ternary complex of Tritrichomonas foetus inosine 5'-monophosphate dehydrogenase: NAD+ orients the active site loop for catalysis
Biochemistry
41
13309-13317
2002
Tritrichomonas suis
Manually annotated by BRENDA team
Guillen Schlippe, Y.V.; Hedstrom, L.
Is Arg418 the catalytic base required for the hydrolysis step of the IMP dehydrogenase reaction?
Biochemistry
44
11700-11707
2005
Tritrichomonas suis
Manually annotated by BRENDA team
Guillen Schlippe, Y.V.; Hedstrom, L.
Guanidine derivatives rescue the Arg418Ala mutation of Tritrichomonas foetus IMP dehydrogenase
Biochemistry
44
16695-16700
2005
Tritrichomonas suis
Manually annotated by BRENDA team
Franchetti, P.; Cappellacci, L.; Pasqualini, M.; Petrelli, R.; Jayaprakasan, V.; Jayaram, H.N.; Boyd, D.B.; Jain, M.D.; Grifantini, M.
Synthesis, conformational analysis, and biological activity of new analogues of thiazole-4-carboxamide adenine dinucleotide (TAD) as IMP dehydrogenase inhibitors
Bioorg. Med. Chem.
13
2045-2053
2005
Homo sapiens
Manually annotated by BRENDA team
Iwanowicz, E.J.; Watterson, S.H.; Guo, J.; Pitts, W.J.; Dhar, T.G.M.; Shen, Z.; Chen, P.; Gu, H.H.; Fleener, C.A.; Rouleau, K.A.; Cheney, D.L.; Townsend, R.M.; Hollenbaugh, D.M.
Inhibitors of inosine monophosphate dehydrogenase: SARs about the N-[3-methoxy-4-(5-oxazolyl)phenyl] moiety
Bioorg. Med. Chem. Lett.
13
2059-2063
2003
Homo sapiens
Manually annotated by BRENDA team
Dhar, T.G.M.; Shen, Z.; Gu, H.H.; Chen, P.; Norris, D.; Watterson, S.H.; Ballentine, S.K.; Fleener, C.A.; Rouleau, K.A.; Barrish, J.C.; Townsend, R.; Hollenbaugh, D.L.; Iwanowicz, E.J.
3-Cyanoindole-based inhibitors of inosine monophosphate dehydrogenase: synthesis and initial structure–activity relationships
Bioorg. Med. Chem. Lett.
13
3557-3560
2003
Homo sapiens
Manually annotated by BRENDA team
Watterson,S.H.; Carlsen, M.; Dhar, T.G.M.; Shen, Z.; Pitts, W.J.; Guo, J.; Gu, H.H.; Norris, D.; Chorba, J.; Chen, P.; Cheney, D.; Witmer, M.; Fleener, C.A.; Rouleau, K.; Townsend, R.; Hollenbaugh D.L.; Iwanowicz, E.J.
Novel inhibitors of IMPDH: a highly potent and selective quinolone-based series
Bioorg. Med. Chem. Lett.
13
543-546
2003
Homo sapiens
Manually annotated by BRENDA team
Birch, H.L.; Buckley, G.M.; Davies, N.; Dyke, H.J.; Frost, E.J.; Gilbert, P.J.; Hannah, D.R.; Haughan, A.F.; Madigan, M.J.; Morgan, T.; Pitt, W.R.; Ratcliffe, A.J.; Ray, N.C.; Richard, M.D.; Sharpe, A.; Taylor, A.J.; Whitworth, J.M.; Williams, S.C.
Novel 7-methoxy-6-oxazol-5-yl-2,3-dihydro-1H-quinazolin-4-ones as IMPDH inhibitors
Bioorg. Med. Chem. Lett.
15
5335-5339
2005
Homo sapiens
Manually annotated by BRENDA team
Buckley, G.M.; Davies, N.; Dyke, H.J.; Gilbert, P.J.; Hannah, D.R.; Haughan, A.F.; Hunt, C.A.; Pitt, W.R.; Profit, R.H.; Ray, N.C.; Richard, M.D.; Sharpe, A.; Taylor, A.J.; Whitworth, J.M.; Williams, S.C.
Quinazolinethiones and quinazolinediones, novel inhibitors of inosine monophosphate dehydrogenase: synthesis and initial structure-activity relationships
Bioorg. Med. Chem. Lett.
15
751-754
2005
Homo sapiens
Manually annotated by BRENDA team
Beevers, R.E.; Buckley, G.M.; Davies, N.; Fraser, J.L.; Galvin, F.C.; Hannah, D.R.; Haughan, A.F.; Jenkins, K.; Mack, S.R.; Pitt, W.R.; Ratcliffe, A.J.; Richard, M.D.; Sabin, V.; Sharpe, A.; Williams, S.C.
Low molecular weight indole fragments as IMPDH inhibitors
Bioorg. Med. Chem. Lett.
16
2535-2538
2006
Homo sapiens
Manually annotated by BRENDA team
Watkins, W.J.; Chen, J.M.; Cho, A.; Chong, L.; Collins, N.; Fardis, M.; Huang, W.; Hung, M.; Kirschberg, T.; Lee, W.A.; Liu, X.; Thomas, W.; Xu, J.; Zeynalzadegan, A.; Zhang, J.
Phosphonic acid-containing analogues of mycophenolic acid as inhibitors of IMPDH
Bioorg. Med. Chem. Lett.
16
3479-3483
2006
Homo sapiens
Manually annotated by BRENDA team
Dubsky, P.C.; Friedl, J.; Stift, A.; Bachleitner-Hofmann, T.; Jakesz, R.; Gnant, M.F.; Weigel, G.
Inosine 5-monophosphate dehydrogenase inhibition by mycophenolic acid impairs maturation and function of dendritic cells
Clin. Chim. Acta
364
139-147
2006
Homo sapiens
Manually annotated by BRENDA team
Hedstrom, L.; Gan, L.
IMP dehydrogenase: structural schizophrenia and an unusual base
Curr. Opin. Chem. Biol.
10
520-525
2006
Homo sapiens, Tritrichomonas suis
Manually annotated by BRENDA team
Koehler, G.A.; Gong, X.; Bentink, S.; Theiss, S.; Pagani, G.M.; Agabian, N.; Hedstrom, L.
The functional basis of mycophenolic acid resistance in Candida albicans IMP dehydrogenase
J. Biol. Chem.
280
11295-11302
2005
Candida albicans, Candida albicans (Q59Q46), Candida albicans CAI4 (Q59Q46)
Manually annotated by BRENDA team
Ji, Y.; Gu, J.; Makhov, A.M.; Griffith, J.D.; Mitchell, B.S.
Regulation of the interaction of inosine monophosphate dehydrogenase with mycophenolic acid by GTP
J. Biol. Chem.
281
206-212
2006
Homo sapiens
Manually annotated by BRENDA team
Chong, C.R.; Qian, D.Z.; Pan, F.; Wei, Y.; Pili, R.; Sullivan, D.J.; Liu, J.O.
Identification of type 1 inosine monophosphate dehydrogenase as an antiangiogenic drug target
J. Med. Chem.
49
2677-2680
2006
Homo sapiens
Manually annotated by BRENDA team
Rejman, D.; Olesiak, M.; Chen, L.; Patterson, S.E.; Wilson, D.; Jayaram, H.N.; Hedstrom, L.; Pankiewicz, K.W.
Novel methylenephosphophosphonate analogues of mycophenolic adenine dinucleotide. Inhibition of inosine monophosphate dehydrogenase
J. Med. Chem.
49
5018-5022
2006
Homo sapiens
Manually annotated by BRENDA team
Penuelas, S.; Noe, V.; Morales, R.; Ciudad, C.J.
Sensitization of human erythroleukemia K562 cells resistant to methotrexate by inhibiting IMPDH
Med. Sci. Monit.
11
BR6-BR12
2005
Homo sapiens
Manually annotated by BRENDA team
Vethe, N.T.; Mandla, R.; Line, P.D.; Midtvedt, K.; Hartmann, A.; Bergan, S.
Inosine monophosphate dehydrogenase activity in renal allograft recipients during mycophenolate treatment
Scand. J. Clin. Lab. Invest.
66
31-44
2006
Homo sapiens
Manually annotated by BRENDA team
Xu, D.; Cobb, G.; Spellicy, C.J.; Bowne, S.J.; Daiger, S.P.; Hedstrom, L.
Retinal isoforms of inosine 5-monophosphate dehydrogenase type 1 are poor nucleic acid binding proteins
Arch. Biochem. Biophys.
472
100-104
2008
Homo sapiens
Manually annotated by BRENDA team
Mizushina, Y.; Dairaku, I.; Yanaka, N.; Takeuchi, T.; Ishimaru, C.; Sugawara, F.; Yoshida, H.; Kato, N.
Inhibitory action of polyunsaturated fatty acids on IMP dehydrogenase
Biochimie
89
581-590
2007
Mus musculus
Manually annotated by BRENDA team
Chen, L.; Petrelli, R.; Olesiak, M.; Wilson, D.J.; Labello, N.P.; Pankiewicz, K.W.
Bis(sulfonamide) isosters of mycophenolic adenine dinucleotide analogues: Inhibition of inosine monophosphate dehydrogenase
Bioorg. Med. Chem.
16
7462-7469
2008
Homo sapiens, Homo sapiens (P12268)
Manually annotated by BRENDA team
Haglund, S.; Taipalensuu, J.; Peterson, C.; Almer, S.
IMPDH activity in thiopurine-treated patients with inflammatory bowel disease - relation to TPMT activity and metabolite concentrations
Br. J. Clin. Pharmacol.
65
69-77
2008
Homo sapiens
Manually annotated by BRENDA team
Bremer, S.; Rootwelt, H.; Bergan, S.
Real-time PCR determination of IMPDH1 and IMPDH2 expression in blood cells
Clin. Chem.
53
1023-1029
2007
Homo sapiens
Manually annotated by BRENDA team
Sanquer, S.; Maison, P.; Tomkiewicz, C.; Macquin-Mavier, I.; Legendre, C.; Barouki, R.; Lang, P.
Expression of inosine monophosphate dehydrogenase type I and type II after mycophenolate mofetil treatment: a 2-year follow-up in kidney transplantation
Clin. Pharmacol. Ther.
83
328-335
2008
Homo sapiens
Manually annotated by BRENDA team
Gunter, J.H.; Thomas, E.C.; Lengefeld, N.; Kruger, S.J.; Worton, L.; Gardiner, E.M.; Jones, A.; Barnett, N.L.; Whitehead, J.P.
Characterisation of inosine monophosphate dehydrogenase expression during retinal development: Differences between variants and isoforms
Int. J. Biochem. Cell Biol.
40
1716-1728
2008
Rattus norvegicus (Q6P9U9)
Manually annotated by BRENDA team
Chen, L.; Gao, G.; Felczak, K.; Bonnac, L.; Patterson, S.E.; Wilson, D.; Bennett, E.M.; Jayaram, H.N.; Hedstrom, L.; Pankiewicz, K.W.
Probing binding requirements of type I and type II isoforms of inosine monophosphate dehydrogenase with adenine-modified nicotinamide adenine dinucleotide analogues
J. Med. Chem.
50
5743-5751
2007
Homo sapiens
Manually annotated by BRENDA team
Chen, L.; Wilson, D.; Jayaram, H.N.; Pankiewicz, K.W.
Dual inhibitors of inosine monophosphate dehydrogenase and histone deacetylases for cancer treatment
J. Med. Chem.
50
6685-6691
2007
Homo sapiens
Manually annotated by BRENDA team
Dobie, F.; Berg, A.; Boitz, J.M.; Jardim, A.
Kinetic characterization of inosine monophosphate dehydrogenase of Leishmania donovani
Mol. Biochem. Parasitol.
152
11-21
2007
Leishmania donovani
Manually annotated by BRENDA team
Pimkin, M.; Markham, G.D.
The CBS subdomain of inosine 5-monophosphate dehydrogenase regulates purine nucleotide turnover
Mol. Microbiol.
68
342-359
2008
Escherichia coli
Manually annotated by BRENDA team
Spellicy, C.J.; Daiger, S.P.; Sullivan, L.S.; Zhu, J.; Liu, Q.; Pierce, E.A.; Bowne, S.J.
Characterization of retinal inosine monophosphate dehydrogenase 1 in several mammalian species
Mol. Vis.
13
1866-1872
2007
Canis lupus familiaris, Homo sapiens, Mus musculus, Ovis aries, Rattus norvegicus
Manually annotated by BRENDA team
Wang, J.; Zeevi, A.; Webber, S.; Girnita, D.M.; Addonizio, L.; Selby, R.; Hutchinson, I.V.; Burckart, G.J.
A novel variant L263F in human inosine 5-monophosphate dehydrogenase 2 is associated with diminished enzyme activity
Pharmacogenet. Genomics
17
283-290
2007
Homo sapiens
Manually annotated by BRENDA team
Vethe, N.T.; Bremer, S.; Bergan, S.
IMP dehydrogenase basal activity in MOLT-4 human leukaemia cells is altered by mycophenolic acid and 6-thioguanosine
Scand. J. Clin. Lab. Invest.
68
277-285
2007
Homo sapiens
Manually annotated by BRENDA team
Patel, C.G.; Richman, K.; Yang, D.; Yan, B.; Gohh, R.Y.; Akhlaghi, F.
Effect of Diabetes mellitus on mycophenolate sodium pharmacokinetics and inosine monophosphate dehydrogenase activity in stable kidney transplant recipients
Ther. Drug Monit.
29
735-742
2007
Homo sapiens
Manually annotated by BRENDA team
Bremer, S.; Mandla, R.; Vethe, N.T.; Rasmussen, I.; Rootwelt, H.; Line, P.D.; Midtvedt, K.; Bergan, S.
Expression of IMPDH1 and IMPDH2 after transplantation and initiation of immunosuppression
Transplantation
85
55-61
2008
Homo sapiens
Manually annotated by BRENDA team
Pimkin, M.; Markham, G.
Inosine 5-monophosphate dehydrogenase
Adv. Enzymol. Relat. Areas Mol. Biol.
76
1-53
2009
Borreliella burgdorferi, Candida albicans, Cricetulus griseus, Cryptosporidium parvum, Enterobacter aerogenes, Escherichia coli, Homo sapiens, Mus musculus, Saccharomyces cerevisiae, Streptococcus pyogenes, Tritrichomonas suis
Manually annotated by BRENDA team
Su, H.; Gunter, J.H.; de Vries, M.; Connor, T.; Wanyonyi, S.; Newell, F.S.; Segal, D.; Molero, J.C.; Reizes, O.; Prins, J.B.; Hutley, L.J.; Walder, K.; Whitehead, J.P.
Inhibition of inosine monophosphate dehydrogenase reduces adipogenesis and diet-induced obesity
Biochem. Biophys. Res. Commun.
386
351-355
2009
Mus musculus
Manually annotated by BRENDA team
Riera, T.V.; Wang, W.; Josephine, H.R.; Hedstrom, L.
A kinetic alignment of orthologous inosine-5-monophosphate dehydrogenases
Biochemistry
47
8689-8696
2008
Cryptosporidium parvum, Homo sapiens
Manually annotated by BRENDA team
Hedstrom, L.
IMP dehydrogenase: Structure, mechanism, and inhibition
Chem. Rev.
109
2903-2928
2009
Borreliella burgdorferi (P49058), Candida albicans, Cricetulus griseus, Cryptosporidium parvum (Q8T6T2), Eimeria tenella, Enterobacter aerogenes, Escherichia coli, Homo sapiens (P12268), Homo sapiens (P20839), Leishmania donovani (P21620), no activity in Giardia lamblia, no activity in Trichomonas vaginalis, Plasmodium falciparum, Pneumocystis carinii (Q12658), Pyrococcus horikoshii, Staphylococcus aureus, Streptococcus pyogenes (P0C0H6), Toxoplasma gondii, Tritrichomonas suis (P50097), Trypanosoma brucei (P50098)
Manually annotated by BRENDA team
Gensburger, O.; Picard, N.; Marquet, P.
Effect of mycophenolate acyl-glucuronide on human recombinant type 2 inosine monophosphate dehydrogenase
Clin. Chem.
55
986-993
2009
Homo sapiens
Manually annotated by BRENDA team
Mino, Y.; Naito, T.; Otsuka, A.; Ozono, S.; Kagawa, Y.; Kawakami, J.
Inosine monophosphate dehydrogenase activity depends on plasma concentrations of mycophenolic acid and its glucuronides in kidney transplant recipients
Clin. Chim. Acta
409
56-61
2009
Homo sapiens
Manually annotated by BRENDA team
Pimkin, M.; Pimkina, J.; Markham, G.D.
A regulatory role of the Bateman domain of IMP dehydrogenase in adenylate nucleotide biosynthesis
J. Biol. Chem.
284
7960-7969
2009
Escherichia coli
Manually annotated by BRENDA team
Bairagya, H.R.; Mukhopadhyay, B.P.; Sekar, K.
An insight to the dynamics of conserved water molecular triad in IMPDH II (human): recognition of cofactor and substrate to catalytic Arg 322
J. Biomol. Struct. Dyn.
27
149-158
2009
Homo sapiens, Homo sapiens (P12268)
Manually annotated by BRENDA team
Maurya, S.K.; Gollapalli, D.R.; Kirubakaran, S.; Zhang, M.; Johnson, C.R.; Benjamin, N.N.; Hedstrom, L.; Cuny, G.D.
Triazole inhibitors of Cryptosporidium parvum inosine 5-monophosphate dehydrogenase
J. Med. Chem.
52
4623-4630
2009
Cryptosporidium parvum
Manually annotated by BRENDA team
Shu, Q.; Nair, V.
Inosine monophosphate dehydrogenase (IMPDH) as a target in drug discovery
Med. Res. Rev.
28
219-232
2008
Borreliella burgdorferi, Cricetulus griseus, Escherichia coli, Homo sapiens (P12268), Homo sapiens (P20839), Leishmania donovani, Mus musculus, Mycobacterium tuberculosis, Pyrococcus horikoshii OT3, Rattus norvegicus, Streptococcus pyogenes, Thermotoga maritima, Tritrichomonas suis
Manually annotated by BRENDA team
Zhang, X.H.; He, K.W.; Duan, Z.T.; Zhou, J.M.; Yu, Z.Y.; Ni, Y.X.; Lu, C.P.
Identification and characterization of inosine 5-monophosphate dehydrogenase in Streptococcus suis type 2
Microb. Pathog.
7
267-273
2009
Streptococcus suis, Streptococcus suis 2
Manually annotated by BRENDA team
Winnicki, W.; Weigel, G.; Sunder-Plassmann, G.; Bajari, T.; Winter, B.; Herkner, H.; Sengoelge, G.
An inosine 5-monophosphate dehydrogenase 2 single-nucleotide polymorphism impairs the effect of mycophenolic acid
Pharmacogenomics J.
10
70-76
2010
Homo sapiens
Manually annotated by BRENDA team
Brandhorst, G.; Marquet, P.; Shaw, L.M.; Liebisch, G.; Schmitz, G.; Coffing, M.J.; Domke, I.; Streit, F.; Luthe, H.; Oellerich, M.
Multicenter evaluation of a new inosine monophosphate dehydrogenase inhibition assay for quantification of total mycophenolic acid in plasma
Ther. Drug Monit.
30
428-433
2008
Homo sapiens
Manually annotated by BRENDA team
Glander, P.; Sombogaard, F.; Budde, K.; van Gelder, T.; Hambach, P.; Liefeldt, L.; Lorkowski, C.; Mai, M.; Neumayer, H.H.; Vulto, A.G.; Mathot, R.A.
Improved assay for the nonradioactive determination of inosine 5-monophosphate dehydrogenase activity in peripheral blood mononuclear cells
Ther. Drug Monit.
31
351-359
2009
Homo sapiens
Manually annotated by BRENDA team
Morrow, C.A.; Stamp, A.; Valkov, E.; Kobe, B.; Fraser, J.A.
Crystallization and preliminary X-ray analysis of mycophenolic acid-resistant and mycophenolic acid-sensitive forms of IMP dehydrogenase from the human fungal pathogen Cryptococcus
Acta Crystallogr. Sect. F
66
1104-1107
2010
Cryptococcus gattii VGIII (E3P6S3), Cryptococcus neoformans, Cryptococcus neoformans H99
Manually annotated by BRENDA team
Park, J.H.; Ahn, S.H.
IMP dehydrogenase is recruited to the transcription complex through serine 2 phosphorylation of RNA polymerase II
Biochem. Biophys. Res. Commun.
392
588-592
2010
Saccharomyces cerevisiae
Manually annotated by BRENDA team
Josephine, H.R.; Ravichandran, K.R.; Hedstrom, L.
The Cys319 loop modulates the transition between dehydrogenase and hydrolase conformations in inosine 5-monophosphate dehydrogenase
Biochemistry
49
10674-10681
2010
Tritrichomonas suis
Manually annotated by BRENDA team
Mitsuhashi, S.; Takenaka, J.; Iwamori, K.; Nakajima, N.; Ubukata, M.
Structure-activity relationships for inhibition of inosine monophosphate dehydrogenase and differentiation induction of K562 cells among the mycophenolic acid derivatives
Bioorg. Med. Chem.
18
8106-8111
2010
Homo sapiens (P12268), Homo sapiens (P20839)
Manually annotated by BRENDA team
Felczak, K.; Chen, L.; Wilson, D.; Williams, J.; Vince, R.; Petrelli, R.; Jayaram, H.N.; Kusumanchi, P.; Kumar, M.; Pankiewicz, K.W.
Cofactor-type inhibitors of inosine monophosphate dehydrogenase via modular approach: Targeting the pyrophosphate binding sub-domain
Bioorg. Med. Chem.
19
1594-1605
2011
Homo sapiens, Homo sapiens (P12268), Homo sapiens (P20839)
Manually annotated by BRENDA team
Dairaku, I.; Han, Y.; Yanaka, N.; Kato, N.
Inhibitory effect of curcumin on IMP dehydrogenase, the target for anticancer and antiviral chemotherapy agents
Biosci. Biotechnol. Biochem.
74
185-187
2010
Homo sapiens, Mus musculus (P24547)
Manually annotated by BRENDA team
Gollapalli, D.R.; Macpherson, I.S.; Liechti, G.; Gorla, S.K.; Goldberg, J.B.; Hedstrom, L.
Structural determinants of inhibitor selectivity in prokaryotic IMP dehydrogenases
Chem. Biol.
17
1084-1091
2010
Borreliella burgdorferi, Escherichia coli, Helicobacter pylori, Streptococcus pyogenes
Manually annotated by BRENDA team
Macpherson, I.S.; Kirubakaran, S.; Gorla, S.K.; Riera, T.V.; DAquino, J.A.; Zhang, M.; Cuny, G.D.; Hedstrom, L.
The structural basis of Cryptosporidium-specific IMP dehydrogenase inhibitor selectivity
J. Am. Chem. Soc.
132
1230-1231
2010
Cryptosporidium parvum, Cryptosporidium parvum (Q8T6T2)
Manually annotated by BRENDA team
Maiguma, T.; Yosida, T.; Otsubo, K.; Okabe, Y.; Sugitani, A.; Tanaka, M.; Oishi, R.; Teshima, D.
Evaluation of inosin-5-monophosphate dehydrogenase activity during maintenance therapy with tacrolimus
J. Clin. Pharm. Ther.
35
79-85
2010
Homo sapiens
Manually annotated by BRENDA team
Chen, L.; Wilson, D.J.; Xu, Y.; Aldrich, C.C.; Felczak, K.; Sham, Y.Y.; Pankiewicz, K.W.
Triazole-linked inhibitors of inosine monophosphate dehydrogenase from human and Mycobacterium tuberculosis
J. Med. Chem.
53
4768-4778
2010
Homo sapiens, Homo sapiens (P12268), Homo sapiens (P20839), Mycobacterium tuberculosis, Mycobacterium tuberculosis H37Rv
Manually annotated by BRENDA team
Collart, F.R.; Osipiuk, J.; Trent, J.; Olsen, G.J.; Huberman, E.
Cloning, characterization and sequence comparison of the gene coding for IMP dehydrogenase from Pyrococcus furiosus
Gene
174
209-216
1996
Pyrococcus furiosus (P42851), Pyrococcus furiosus
Manually annotated by BRENDA team
Rao, V.A.; Shepherd, S.M.; Owen, R.; Hunter, W.N.
Structure of Pseudomonas aeruginosa inosine 5-monophosphate dehydrogenase
Acta Crystallogr. Sect. F
69
243-247
2013
Pseudomonas aeruginosa, Pseudomonas aeruginosa (Q9HXM5)
Manually annotated by BRENDA team
Riera, T.V.; Zheng, L.; Josephine, H.R.; Min, D.; Yang, W.; Hedstrom, L.
Allosteric activation via kinetic control: potassium accelerates a conformational change in IMP dehydrogenase
Biochemistry
50
8508-8518
2011
Cryptosporidium parvum (Q8T6T2)
Manually annotated by BRENDA team
Makowska-Grzyska, M.; Kim, Y.; Wu, R.; Wilton, R.; Gollapalli, D.R.; Wang, X.K.; Zhang, R.; Jedrzejczak, R.; Mack, J.C.; Maltseva, N.; Mulligan, R.; Binkowski, T.A.; Gornicki, P.; Kuhn, M.L.; Anderson, W.F.; Hedstrom, L.; Joachimiak, A.
Bacillus anthracis inosine 5-monophosphate dehydrogenase in action: the first bacterial series of structures of phosphate ion-, substrate-, and product-bound complexes
Biochemistry
51
6148-6163
2012
Bacillus anthracis, Bacillus anthracis (Q81W29), Campylobacter jejuni
Manually annotated by BRENDA team
Johnson, C.R.; Gorla, S.K.; Kavitha, M.; Zhang, M.; Liu, X.; Striepen, B.; Mead, J.R.; Cuny, G.D.; Hedstrom, L.
Phthalazinone inhibitors of inosine-5-monophosphate dehydrogenase from Cryptosporidium parvum
Bioorg. Med. Chem. Lett.
23
1004-1007
2013
Cryptosporidium parvum, Cryptosporidium parvum (Q8T6T2)
Manually annotated by BRENDA team
Hansen, B.; Genee, H.; Kaas, C.; Nielsen, J.; Regueira, T.; Mortensen, U.; Frisvad, J.; Patil, K.
A new class of IMP dehydrogenase with a role in self-resistance of mycophenolic acid producing fungi
BMC Microbiol.
11
202
2011
Penicillium brevicompactum (F1DBB2), Penicillium brevicompactum
Manually annotated by BRENDA team
Gorla, S.K.; Kavitha, M.; Zhang, M.; Liu, X.; Sharling, L.; Gollapalli, D.R.; Striepen, B.; Hedstrom, L.; Cuny, G.D.
Selective and potent urea inhibitors of cryptosporidium parvum inosine 5-monophosphate dehydrogenase
J. Med. Chem.
55
7759-7771
2012
Cryptosporidium parvum, Cryptosporidium parvum (Q8T6T2)
Manually annotated by BRENDA team
Gorla, S.K.; Kavitha, M.; Zhang, M.; Chin, J.E.; Liu, X.; Striepen, B.; Makowska-Grzyska, M.; Kim, Y.; Joachimiak, A.; Hedstrom, L.; Cuny, G.D.
Optimization of benzoxazole-based inhibitors of Cryptosporidium parvum inosine 5-monophosphate dehydrogenase
J. Med. Chem.
56
4028-4043
2013
Cryptosporidium parvum, Cryptosporidium parvum (Q8T6T2)
Manually annotated by BRENDA team
Cao, S.; Aboge, G.O.; Terkawi, M.A.; Zhou, M.; Luo, Y.; Yu, L.; Li, Y.; Goo, Y.; Kamyingkird, K.; Masatani, T.; Suzuki, H.; Igarashi, I.; Nishikawa, Y.; Xuan, X.
Cloning, characterization and validation of inosine 5-monophosphate dehydrogenase of Babesia gibsoni as molecular drug target
Parasitol. Int.
62
87-94
2013
Babesia gibsoni, Babesia gibsoni (I3WTS0)
Manually annotated by BRENDA team
Bessho, T.; Morii, S.; Kusumoto, T.; Shinohara, T.; Noda, M.; Uchiyama, S.; Shuto, S.; Nishimura, S.; Djikeng, A.; Duszenko, M.; Martin, S.K.; Inui, T.; Kubata, K.B.
Characterization of the novel Trypanosoma brucei inosine 5-monophosphate dehydrogenase
Parasitology
140
735-745
2013
Trypanosoma brucei (Q387Q3), Trypanosoma brucei
Manually annotated by BRENDA team
Thomas, E.C.; Gunter, J.H.; Webster, J.A.; Schieber, N.L.; Oorschot, V.; Parton, R.G.; Whitehead, J.P.
Different characteristics and nucleotide binding properties of inosine monophosphate dehydrogenase (IMPDH) isoforms
PLoS ONE
7
e51096
2012
Homo sapiens, Homo sapiens (P12268), Homo sapiens (P20839)
Manually annotated by BRENDA team
Park, S.J.; Joo, W.A.; Choi, J.; Lee, S.H.; Kim, C.W.
Identification and characterization of inosine monophosphate dehydrogenase from Halobacterium salinarum
Proteomics
4
3632-3641
2004
Halobacterium salinarum, Halobacterium salinarum NRC 34002
Manually annotated by BRENDA team