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Literature summary for 1.1.1.205 extracted from

  • Haglund, S.; Taipalensuu, J.; Peterson, C.; Almer, S.
    IMPDH activity in thiopurine-treated patients with inflammatory bowel disease - relation to TPMT activity and metabolite concentrations (2008), Br. J. Clin. Pharmacol., 65, 69-77.
    View publication on PubMedView publication on EuropePMC

Application

Application Comment Organism
medicine study on inosine 5'-phosphate activity in thiopurine-treated patients with inflammatory bowel disease. Negative correlation between inosine 5'-phosphate dehydrogenase activity and dose-normalized 6-methylthioinosine concentrations, no evident correlation to 6-thioguanine nucleotide or the 6-methylthioinosine/6-thioguanine nucleotide ratio Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
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thiopurine-treated patients with inflammatory bowel disease
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Source Tissue

Source Tissue Comment Organism Textmining
blood
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Homo sapiens
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peripheral blood mononuclear cell
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Homo sapiens
-